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The map label for this gene is ybhD [H]

Identifier: 21244201

GI number: 21244201

Start: 4109222

End: 4110124

Strand: Reverse

Name: ybhD [H]

Synonym: XAC3476

Alternate gene names: 21244201

Gene position: 4110124-4109222 (Counterclockwise)

Preceding gene: 21244205

Following gene: 21244196

Centisome position: 79.41

GC content: 64.89

Gene sequence:

>903_bases
GTGACCATCAAATTCGACCTCAACGATCTGCAGGCATTCCGTGCCGTCGCCGAGAACGGCAGCTTTCGCCGCGCTGCCGA
ACGCATCCGCATCACGCAGCCGGCGCTCAGCCGCAGGATCGACAAGCTCGAGTCGGCGTTGAACGTCAAGCTGTTCGAGC
GCACCACGCGCAAGGTTGCGCTCACCACCGTCGGCCAGGCGTTCATGCCGCAGGTCGAGCGCATGCTCGACGATCTGGAT
ATGGCGCTGATGAACATCGGCGATGCAGGGTCCAGCAGGATGGGCACGGTGACCGTGGCCTGCGTGCCGTCTGCGGCGTA
CTACTTCATGCCGCAGGCAATCCACGGGCTGCATCAGCTGTTTCCGAAGATCCGCATCCGGCTGTTCGACGGCAGCGCCA
GTCATGTCAGTGCGGCAGTGGCCTCCGGCGAAGCGGATTTCGGGGTCAGCTTCAGCGGTAACCTGGCGCCGGAGGTGGAG
TTCGAGCCGTTGTTGCAGGAGCGCTATGTGATTGCCTGCCGCCAGGACCATCCGCTGTCCGGGCGCGCACAGGTCAGCTG
GCAGGAGGCCTACGGTTACGACTACATCACGTTGGACAAGACATCGGGCAACCGGCTGGTGCTGGATCGGGCGCTGGCTG
CATTCACGCCGGACAAGCCCAGCATCTGCGAGACCCGCCATGTCACCACGTTGCTGGGGTTGGTGGAGGCCGGCGTCGGT
ATTGCCGCCGTGCCTTCCATTGCCATGCCCTCCGGCCCGCATCCGGTGCTGGCGGCGGTGCCGCTGGTCGAACCGGAGGT
ATCGCGCAACGTGGGACTTCTCAAACGTCGCGGACGCACGCTGACACCGACCGCGCTGGAACTGGCGGAACTGGTGCGAC
GGATGCCCGCACGTTCAAGGTGA

Upstream 100 bases:

>100_bases
CAATGCATCCGAATGCAGCGACTTGTCGGCGTCAGACGCAGCACCGCAGGCAAGCGTCTATGCTATGGCGACCGCCATCG
AACACTGAAGCTGCGGCACC

Downstream 100 bases:

>100_bases
CACCGGATCCAGGCCGGTCGCGCGCGCAACCGCCTGCGCCTCGCCCGACTGCAGGTACGTAAGCAGGCGCCTGGCCGCTT
CGGGGTGCTGCGCGTTGACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVALTTVGQAFMPQVERMLDDLD
MALMNIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVE
FEPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSR

Sequences:

>Translated_300_residues
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVALTTVGQAFMPQVERMLDDLD
MALMNIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVE
FEPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSR
>Mature_299_residues
TIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVALTTVGQAFMPQVERMLDDLDM
ALMNIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQLFPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEF
EPLLQERYVIACRQDHPLSGRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVGI
AAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=42.1602787456446, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI1788748, Length=291, Percent_Identity=32.9896907216495, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=30.6122448979592, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787601, Length=302, Percent_Identity=27.4834437086093, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789204, Length=239, Percent_Identity=25.1046025104602, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.1604938271605, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081904, Length=178, Percent_Identity=29.7752808988764, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787530, Length=259, Percent_Identity=24.3243243243243, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790208, Length=266, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=26.0162601626016, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=26.9709543568465, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787589, Length=154, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788296, Length=215, Percent_Identity=25.1162790697674, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789506, Length=177, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=153, Percent_Identity=30.718954248366, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786713, Length=192, Percent_Identity=32.8125, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787128, Length=126, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=147, Percent_Identity=31.2925170068027, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790262, Length=249, Percent_Identity=21.285140562249, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=169, Percent_Identity=26.0355029585799, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786401, Length=122, Percent_Identity=31.9672131147541, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786508, Length=184, Percent_Identity=26.6304347826087, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=172, Percent_Identity=29.0697674418605, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32813; Mature: 32682

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVA
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTVGQAFMPQVERMLDDLDMALMNIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHH
FPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEFEPLLQERYVIACRQDHPLS
HHHHEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEECCCCCCC
GRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
CCEEEEEHHHCCCEEEEEECCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSR
CEECCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TIKFDLNDLQAFRAVAENGSFRRAAERIRITQPALSRRIDKLESALNVKLFERTTRKVA
EEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTVGQAFMPQVERMLDDLDMALMNIGDAGSSRMGTVTVACVPSAAYYFMPQAIHGLHQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHH
FPKIRIRLFDGSASHVSAAVASGEADFGVSFSGNLAPEVEFEPLLQERYVIACRQDHPLS
HHHHEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHCCEEEEECCCCCCC
GRAQVSWQEAYGYDYITLDKTSGNRLVLDRALAAFTPDKPSICETRHVTTLLGLVEAGVG
CCEEEEEHHHCCCEEEEEECCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
IAAVPSIAMPSGPHPVLAAVPLVEPEVSRNVGLLKRRGRTLTPTALELAELVRRMPARSR
CEECCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]