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The map label for this gene is cadC [H]

Identifier: 21244171

GI number: 21244171

Start: 4059601

End: 4061955

Strand: Reverse

Name: cadC [H]

Synonym: XAC3446

Alternate gene names: 21244171

Gene position: 4061955-4059601 (Counterclockwise)

Preceding gene: 21244172

Following gene: 21244170

Centisome position: 78.48

GC content: 66.92

Gene sequence:

>2355_bases
ATGCCATCGGGCCGGCTACGGGTCGGCCAGTGCGTGGTCGACGTTGCCTCGCGCGAGGTGCACGCACCTGGCGCAAAGCG
TCCGCTGCGGCTGGCGCCCAAATCCCTGGCAGTGTTGCTGACCCTGGCGCGGCAGCCGGGCCAGGTGGTCACGCGCGAGC
AACTGCTGGCCGAGGTTTGGCCCGATACATTGCCGACCAACGATGTGGTGACCCAGGCGGTCACGCAGCTGCGCAAGGCG
TTTGCCAGCCACGGCGGGCAGCGCTCGGAGCACATCGAGACCATCGCCAAGACCGGGTATCGCTTGATGGCGGCGGTTGT
GTGGGAAGCGCATGCACCTGCATCGGCAACGCTGCCGGATGAGGCACCTGATTCGGATGCGTTCGAGCCGGCTCAGCCAC
ACGCAGGCGTGGCGTCGGTCCCCGCGCAGTCCGATACTGTTGCACCACCCATCCGCGCCGCGCGTGGTCAGCCTGTGGCG
CCCGTCGCTGCGGAACCGGCCGCTTCGACGCCGGCCGCGCCGCGGCAACGGCGCTCGATGGCGCTGGCAGTCGCCTGCGT
GGCGTTGCTGGTCGTGCTGGGGCTTGCGGCATGGACCTCATGGCGACGTGCCCCGGCGCCTGAGGCCGCGCAAGCGCCTG
CGGTCTTGGGCAGCCCCAAGCGGCCGTATCAGGTGATTACCGCAGGCGGTGGCTTCGATCTCACGCCAAGCCTGTCGCCC
GATGGCGCGATGGTGGCGTACGCCTCATTGACCGGCGATCGTGCCGGCACCTCGATCCTGGTCAAGACCACCGACAACGC
CTATCCGCGGGTACTGGAGACGCCTGGACCCGGCGTCTCCGATCGTTTGCCGGCGTGGTCGCCGGATGGCCGCCAGATCG
CGTTTTCCAGGCAGGCGCCCGATGGGAGCTGCCGGATCATGATCGCTGCGGCCACCGGGCCGGCGGCCTCGCGCGAGCTC
GTGCGGTGCGATGGTGCCGACATGCTGAGTTTCAGCTGGTCGCCGGATGGGCGCGCGCTGGTATTTGGCAGCATGACCGG
CACGCGCGGCGCGGTCCGCATGCGTCGCCTGGATCTGGCAACCAGGCAGTGGCAGGCGCTGGACTACCCGGCGCAGGCGG
GTGATTTCGATTACGCGCCGCGGTATTCGCCCGATGGGAATTGGATTGTCTTTCTACGTAATCCGCAGCTCGGGGACCTG
TGGCGGATTCCGGCCGAAGGCGGCGTTGCCGAACGGCTCACCCATGACAACGCCGATATCCGTGGATGGAGTTGGCTGCC
CGACGGCAGCGGTTTGATCTTCGGGCGTCGCGTGGACAGCGAGGCGCGGCTGTATCGCCTCGATCTGCGAGACCACAGCT
TGCACGATGTGGGCGTGGACGATGCGCAGGCACCGGACGTGGCGCACGGCCATCTGGTGTTCGTGCAACGCAAGCCGCAA
TTCGGCGTCTACCAGGTCATTGGCGACACGATGAACGGCGGCTACATTCGACGCCGCCTGTTTCCATCCAGCGGGCGCGA
CGATCAGCCGATGATCGCGCCGGACGGGCGCCAGCTGATCTTTGCATCCAATCGATCCGGTGCGTACGGGCTGTGGTGGG
GCGATGTCAGCAAGCCCGGCTCGGTGCGCTTGATCGAAGGGCTGCGCCCGGATTCTCGCCAGGCCGCCGACTGGTCAGCC
GATTCGCAACGCGTGCTGGTCAGCGGCAGCGATGCAGCCGGGCATGCCGCGTTGTTCGAAGTGACCCCCGGTAGCGGCCA
GGTGGTGCGACTGCCTGTGCCGCAGCCGCGCCCGCTGCAGGCGATCCATCTTCCCGACCCCCACCGGTTGCTGGTGCTTG
CTGCTGCCGACGACGGGCATACCTTCGCAACGCTGTACGACCGGCGCAGCAGCCCATGGCGCGCGCTGGCAACGCTGCAG
GACGTTTCGCAACTACGCCTGGACCGCGTCAGCGGACAGGTGTTGCTGACTCGTCTCAGCGGCGGCGGTGTCTGGCAGGT
CGCTCCGTCGCTGGCGGCCGATACCTTGCATGCCGTCGATCCGCAGCAGCCGTCGCGCTGGCGGTATCGCAGTTGGGCGC
CGGGCGTGAATGGCCAGCTGCATTACCTGTCGTCGACCGACAGTTGCGCTGCCTACGATAGCGAGCTGCGCAGCGGTCGC
GGCCAGTGTCTGGATGCGGTCAAGTTCACCACCATCAACGGTTTCAGCCTGAACCAGCATGACGGGACGCTGTATGTGTC
GCTGGCCGAAGAAGATGGCAGCGCTATTGCGTACATGGCGCTGCCGCAGCATTCCGTGGCGCCTGTTGGCGTCATTGCTA
ACTTATTGTCGGTATTGAGAAAAATTACCTCGTAA

Upstream 100 bases:

>100_bases
TTGCCGAATTTGGCGTTTCGCGAAAAGCGCGGGGCGCTCTTTGTTGTTCTTGCATGCCGACGCGTGTTTTTTGCCGATGA
GTGTTCCTCCCGTCATTGCA

Downstream 100 bases:

>100_bases
GTTCTTCGGAAAGGCTTCGTGGCAATTTCGGCACAGTTTCGTCAAAACTTCCTGACCGACGCCACATTCGGCAAAACACT
ACGCCCTCTTTTGTACAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MPSGRLRVGQCVVDVASREVHAPGAKRPLRLAPKSLAVLLTLARQPGQVVTREQLLAEVWPDTLPTNDVVTQAVTQLRKA
FASHGGQRSEHIETIAKTGYRLMAAVVWEAHAPASATLPDEAPDSDAFEPAQPHAGVASVPAQSDTVAPPIRAARGQPVA
PVAAEPAASTPAAPRQRRSMALAVACVALLVVLGLAAWTSWRRAPAPEAAQAPAVLGSPKRPYQVITAGGGFDLTPSLSP
DGAMVAYASLTGDRAGTSILVKTTDNAYPRVLETPGPGVSDRLPAWSPDGRQIAFSRQAPDGSCRIMIAAATGPAASREL
VRCDGADMLSFSWSPDGRALVFGSMTGTRGAVRMRRLDLATRQWQALDYPAQAGDFDYAPRYSPDGNWIVFLRNPQLGDL
WRIPAEGGVAERLTHDNADIRGWSWLPDGSGLIFGRRVDSEARLYRLDLRDHSLHDVGVDDAQAPDVAHGHLVFVQRKPQ
FGVYQVIGDTMNGGYIRRRLFPSSGRDDQPMIAPDGRQLIFASNRSGAYGLWWGDVSKPGSVRLIEGLRPDSRQAADWSA
DSQRVLVSGSDAAGHAALFEVTPGSGQVVRLPVPQPRPLQAIHLPDPHRLLVLAAADDGHTFATLYDRRSSPWRALATLQ
DVSQLRLDRVSGQVLLTRLSGGGVWQVAPSLAADTLHAVDPQQPSRWRYRSWAPGVNGQLHYLSSTDSCAAYDSELRSGR
GQCLDAVKFTTINGFSLNQHDGTLYVSLAEEDGSAIAYMALPQHSVAPVGVIANLLSVLRKITS

Sequences:

>Translated_784_residues
MPSGRLRVGQCVVDVASREVHAPGAKRPLRLAPKSLAVLLTLARQPGQVVTREQLLAEVWPDTLPTNDVVTQAVTQLRKA
FASHGGQRSEHIETIAKTGYRLMAAVVWEAHAPASATLPDEAPDSDAFEPAQPHAGVASVPAQSDTVAPPIRAARGQPVA
PVAAEPAASTPAAPRQRRSMALAVACVALLVVLGLAAWTSWRRAPAPEAAQAPAVLGSPKRPYQVITAGGGFDLTPSLSP
DGAMVAYASLTGDRAGTSILVKTTDNAYPRVLETPGPGVSDRLPAWSPDGRQIAFSRQAPDGSCRIMIAAATGPAASREL
VRCDGADMLSFSWSPDGRALVFGSMTGTRGAVRMRRLDLATRQWQALDYPAQAGDFDYAPRYSPDGNWIVFLRNPQLGDL
WRIPAEGGVAERLTHDNADIRGWSWLPDGSGLIFGRRVDSEARLYRLDLRDHSLHDVGVDDAQAPDVAHGHLVFVQRKPQ
FGVYQVIGDTMNGGYIRRRLFPSSGRDDQPMIAPDGRQLIFASNRSGAYGLWWGDVSKPGSVRLIEGLRPDSRQAADWSA
DSQRVLVSGSDAAGHAALFEVTPGSGQVVRLPVPQPRPLQAIHLPDPHRLLVLAAADDGHTFATLYDRRSSPWRALATLQ
DVSQLRLDRVSGQVLLTRLSGGGVWQVAPSLAADTLHAVDPQQPSRWRYRSWAPGVNGQLHYLSSTDSCAAYDSELRSGR
GQCLDAVKFTTINGFSLNQHDGTLYVSLAEEDGSAIAYMALPQHSVAPVGVIANLLSVLRKITS
>Mature_783_residues
PSGRLRVGQCVVDVASREVHAPGAKRPLRLAPKSLAVLLTLARQPGQVVTREQLLAEVWPDTLPTNDVVTQAVTQLRKAF
ASHGGQRSEHIETIAKTGYRLMAAVVWEAHAPASATLPDEAPDSDAFEPAQPHAGVASVPAQSDTVAPPIRAARGQPVAP
VAAEPAASTPAAPRQRRSMALAVACVALLVVLGLAAWTSWRRAPAPEAAQAPAVLGSPKRPYQVITAGGGFDLTPSLSPD
GAMVAYASLTGDRAGTSILVKTTDNAYPRVLETPGPGVSDRLPAWSPDGRQIAFSRQAPDGSCRIMIAAATGPAASRELV
RCDGADMLSFSWSPDGRALVFGSMTGTRGAVRMRRLDLATRQWQALDYPAQAGDFDYAPRYSPDGNWIVFLRNPQLGDLW
RIPAEGGVAERLTHDNADIRGWSWLPDGSGLIFGRRVDSEARLYRLDLRDHSLHDVGVDDAQAPDVAHGHLVFVQRKPQF
GVYQVIGDTMNGGYIRRRLFPSSGRDDQPMIAPDGRQLIFASNRSGAYGLWWGDVSKPGSVRLIEGLRPDSRQAADWSAD
SQRVLVSGSDAAGHAALFEVTPGSGQVVRLPVPQPRPLQAIHLPDPHRLLVLAAADDGHTFATLYDRRSSPWRALATLQD
VSQLRLDRVSGQVLLTRLSGGGVWQVAPSLAADTLHAVDPQQPSRWRYRSWAPGVNGQLHYLSSTDSCAAYDSELRSGRG
QCLDAVKFTTINGFSLNQHDGTLYVSLAEEDGSAIAYMALPQHSVAPVGVIANLLSVLRKITS

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: COG3710

COG function: function code K; DNA-binding winged-HTH domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=157, Percent_Identity=28.0254777070064, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 84095; Mature: 83964

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGRLRVGQCVVDVASREVHAPGAKRPLRLAPKSLAVLLTLARQPGQVVTREQLLAEVW
CCCCCEEHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PDTLPTNDVVTQAVTQLRKAFASHGGQRSEHIETIAKTGYRLMAAVVWEAHAPASATLPD
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEHHHHHHCCCCCCCCCCC
EAPDSDAFEPAQPHAGVASVPAQSDTVAPPIRAARGQPVAPVAAEPAASTPAAPRQRRSM
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
ALAVACVALLVVLGLAAWTSWRRAPAPEAAQAPAVLGSPKRPYQVITAGGGFDLTPSLSP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHCCCCCCCEEEEEECCCCCCCCCCCC
DGAMVAYASLTGDRAGTSILVKTTDNAYPRVLETPGPGVSDRLPAWSPDGRQIAFSRQAP
CCCEEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
DGSCRIMIAAATGPAASRELVRCDGADMLSFSWSPDGRALVFGSMTGTRGAVRMRRLDLA
CCCEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
TRQWQALDYPAQAGDFDYAPRYSPDGNWIVFLRNPQLGDLWRIPAEGGVAERLTHDNADI
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHCCCCCCC
RGWSWLPDGSGLIFGRRVDSEARLYRLDLRDHSLHDVGVDDAQAPDVAHGHLVFVQRKPQ
CCEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
FGVYQVIGDTMNGGYIRRRLFPSSGRDDQPMIAPDGRQLIFASNRSGAYGLWWGDVSKPG
CCEEEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCEEEEECCCCCEEEEEECCCCCCC
SVRLIEGLRPDSRQAADWSADSQRVLVSGSDAAGHAALFEVTPGSGQVVRLPVPQPRPLQ
CEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCE
AIHLPDPHRLLVLAAADDGHTFATLYDRRSSPWRALATLQDVSQLRLDRVSGQVLLTRLS
EEECCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GGGVWQVAPSLAADTLHAVDPQQPSRWRYRSWAPGVNGQLHYLSSTDSCAAYDSELRSGR
CCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCC
GQCLDAVKFTTINGFSLNQHDGTLYVSLAEEDGSAIAYMALPQHSVAPVGVIANLLSVLR
CCEEEEEEEEEECCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KITS
HHCC
>Mature Secondary Structure 
PSGRLRVGQCVVDVASREVHAPGAKRPLRLAPKSLAVLLTLARQPGQVVTREQLLAEVW
CCCCEEHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PDTLPTNDVVTQAVTQLRKAFASHGGQRSEHIETIAKTGYRLMAAVVWEAHAPASATLPD
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEHHHHHHCCCCCCCCCCC
EAPDSDAFEPAQPHAGVASVPAQSDTVAPPIRAARGQPVAPVAAEPAASTPAAPRQRRSM
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
ALAVACVALLVVLGLAAWTSWRRAPAPEAAQAPAVLGSPKRPYQVITAGGGFDLTPSLSP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHCCCCCCCEEEEEECCCCCCCCCCCC
DGAMVAYASLTGDRAGTSILVKTTDNAYPRVLETPGPGVSDRLPAWSPDGRQIAFSRQAP
CCCEEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
DGSCRIMIAAATGPAASRELVRCDGADMLSFSWSPDGRALVFGSMTGTRGAVRMRRLDLA
CCCEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
TRQWQALDYPAQAGDFDYAPRYSPDGNWIVFLRNPQLGDLWRIPAEGGVAERLTHDNADI
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHCCCCCCC
RGWSWLPDGSGLIFGRRVDSEARLYRLDLRDHSLHDVGVDDAQAPDVAHGHLVFVQRKPQ
CCEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
FGVYQVIGDTMNGGYIRRRLFPSSGRDDQPMIAPDGRQLIFASNRSGAYGLWWGDVSKPG
CCEEEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCEEEEECCCCCEEEEEECCCCCCC
SVRLIEGLRPDSRQAADWSADSQRVLVSGSDAAGHAALFEVTPGSGQVVRLPVPQPRPLQ
CEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCE
AIHLPDPHRLLVLAAADDGHTFATLYDRRSSPWRALATLQDVSQLRLDRVSGQVLLTRLS
EEECCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GGGVWQVAPSLAADTLHAVDPQQPSRWRYRSWAPGVNGQLHYLSSTDSCAAYDSELRSGR
CCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCC
GQCLDAVKFTTINGFSLNQHDGTLYVSLAEEDGSAIAYMALPQHSVAPVGVIANLLSVLR
CCEEEEEEEEEECCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KITS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]