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The map label for this gene is dcp [H]

Identifier: 21242208

GI number: 21242208

Start: 1680515

End: 1682713

Strand: Reverse

Name: dcp [H]

Synonym: XAC1456

Alternate gene names: 21242208

Gene position: 1682713-1680515 (Counterclockwise)

Preceding gene: 21242210

Following gene: 21242204

Centisome position: 32.51

GC content: 62.03

Gene sequence:

>2199_bases
TTGACCACCCGTCTCGCTTTTGCCCTGGCCGCCTCCCTGGGACTTGCCATGCCGTCCTACAGCATCGCCGCCCCCGCTGC
CACGCAGGCCGCCACCCAAGCCAACCCCTTCTTCGCCGACAGCACGCTGCCGCTGCATTACCCGCAGTTCGACAAAATTA
AGGACAGCGATTTCGCACCTGCCTTCGATGCGGGCATGGCCGAGCAGTTGAAGGAAGTGGAAAAAATCGCCAGCCAGAAG
GCCAAGCCCAGTTTCGACAACACCATCATCGCGCTGGAAAAGAGCGGTGCCACGCTCGACCGCGCCACCACGGTGTTCTT
CAACCTGGTCGGCGCAGACACCAACGACGCACGCAAGAAATTGCAAGCCGACTATTCGGCGAAGTTCGCAGCGCACCGCG
ATGCGATTTCGCTCAACGGCAAGCTGTTCGCACGCATCCAGACCTTGTACGACCAACGCGCCAAGCTGGGGCTGGATGCG
CAGGGCGTGCGCCTGGTCGAGAAGTACTACAGCGACTTCGTGCGCGACGGCGCCAAGCTCTCCGACGCCGACAAGACCAC
GCTCAAGGCTATGAATGCCGAGCTGGCCAACCTGGGCACCACTTTCAGCCAGAACGTGCTGGCCGAAGTGAATGCTGCCG
CTGTGGTCGTGGACGACGTCAAGCAACTGGATGGTTTGTCGCAGGAGCAGATTGCCGCTGCCGCCGAAGCCGCCAAGGCA
CGCAAGCTCGACGGCAAGTACGTCATCGCGCTGCTCAATACCACCGGCCAACCGCCGCTGACCCAGCTGAAGAATCGCGA
GCTGCGCAAGAAGATCTACGACGCCTCGGTGTCGCGCGGCAGCCACGGCGGCCAGTACGACAACACCGCGCTGGTGGCGC
GCATCATGAAGCTGCGTGCCGACAAGGCCAAGTTGCTGGGCTTCCCAACCTATGCCGCCTACTCGCTGGAAAACCAGACC
GCCAAGACCCCCGAAGCGGTCAACGCGATGCTGGGCAAACTGGCACCGGCCGCGGTGGCCAATGCCAAGCGCGAAGCCGC
CGATCTGCAGGCGATGATCGACAAGGAACAAAAGGCCGCGCGCAAGCCGACCTTCAAGCTCGAAGCCTGGGATTGGGCCT
ACTACAGCGAGAAGGTGCGCCAGGCCAAGTACAACTTCGACGAATCGCAGCTCAAGCCGTACTTCGAGTTGAAGAACGTG
CTGGAAAACGGCGTGTTCTATGCGGCCAATCAGGAATACGGCCTGACCTTCAAGCAGCGCACCGACCTGCCGACCTACCG
CGACGACATCACCGTCTACGACGTGTTCGACGCGGACGGCAAGCAGTTGGCGATCTTCATTGCCGACATGTATGCGCGCG
AATCCAAGCGCGGTGGCGCATGGATGAACTCCTATGTGTCGCAGTCGGACCTGACCGGCTTCAAGCCGGTGGTGGCCAAC
CACCTCAACATTCCCAAGCCGCCGGCCGGCCAGCCGACGCTGCTGACCTGGGATGAGGTGACCACCATGTTCCATGAGTT
CGGGCATGCGCTGCACGGCATGTTTTCCGACGTCAAATACCCGTATTTCTCCGGTACCAGCGTGCCGCGCGACTTCGTCG
AGTTCCCCTCGCAGGTCAACGAGATGTGGGCCGACGAGCCGTCCATCCTGAAGAACTACGCCAAGCATTATCAGAACGGC
ACGCCGATGCCACAGGCATTGCTGGACAAGGTGATTGCCGCATCCAAGTTCAACCAGGGCTTTGCCACCACCGAGTACCT
GGGTGCGGCAATGCTGGATCAGAACTGGCACCAGGTCAGCGCCAACCAGGTGCCAGACGCCGCTGGCGTGATGGCATTCG
AAGCCAAGGCGCTGCAGCAGGACGGCATTGCTTATGCACCGGTGCCGCCGCGCTACAAGACCCCGTATTTCAGCCACATC
ATGGGCGGTTACGCGGCAGGCTACTACGCCTACATCTGGTCGGAAGTGCTGGACGCCAACACCCAGCAGTGGTTCAAGCA
GCACGGTGGCCTGAGCCGCGCCAATGGCGATCGTTTCCGCAAAACCCTGCTTTCGCGCGGCGGTAGCGTGGATGCGATGG
AGCTGTTCCAGAACTTCGCCGGGCATGCCCCGCAGATCGAGCCGCTGCTCGAAAAGCGCGGTCTCAGCGCGCAAGGCGGC
GATGGTGCGACACCGGAAGCGCCGCAGTCCAGGCCGTAA

Upstream 100 bases:

>100_bases
CCTGATGGCGTTGCATTGGCTTGGCAGCCATGCCTTTTGTCACACGCCTGTCCCGACTGGCTGGGTTAGCCTCGGCGGTT
CGCACTTTGGAGCAACTCTC

Downstream 100 bases:

>100_bases
ATCGGCTGCACGATCCGCGCGCGGTGGTGAGGCCGCGCGTGTGGCGGCAGGATCGGCATATCCCCTTCGGGCATGCCGAT
CTTGGACATCAGACGAGACA

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MTTRLAFALAASLGLAMPSYSIAAPAATQAATQANPFFADSTLPLHYPQFDKIKDSDFAPAFDAGMAEQLKEVEKIASQK
AKPSFDNTIIALEKSGATLDRATTVFFNLVGADTNDARKKLQADYSAKFAAHRDAISLNGKLFARIQTLYDQRAKLGLDA
QGVRLVEKYYSDFVRDGAKLSDADKTTLKAMNAELANLGTTFSQNVLAEVNAAAVVVDDVKQLDGLSQEQIAAAAEAAKA
RKLDGKYVIALLNTTGQPPLTQLKNRELRKKIYDASVSRGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAAYSLENQT
AKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQAKYNFDESQLKPYFELKNV
LENGVFYAANQEYGLTFKQRTDLPTYRDDITVYDVFDADGKQLAIFIADMYARESKRGGAWMNSYVSQSDLTGFKPVVAN
HLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKNYAKHYQNG
TPMPQALLDKVIAASKFNQGFATTEYLGAAMLDQNWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPPRYKTPYFSHI
MGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRANGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLSAQGG
DGATPEAPQSRP

Sequences:

>Translated_732_residues
MTTRLAFALAASLGLAMPSYSIAAPAATQAATQANPFFADSTLPLHYPQFDKIKDSDFAPAFDAGMAEQLKEVEKIASQK
AKPSFDNTIIALEKSGATLDRATTVFFNLVGADTNDARKKLQADYSAKFAAHRDAISLNGKLFARIQTLYDQRAKLGLDA
QGVRLVEKYYSDFVRDGAKLSDADKTTLKAMNAELANLGTTFSQNVLAEVNAAAVVVDDVKQLDGLSQEQIAAAAEAAKA
RKLDGKYVIALLNTTGQPPLTQLKNRELRKKIYDASVSRGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAAYSLENQT
AKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQAKYNFDESQLKPYFELKNV
LENGVFYAANQEYGLTFKQRTDLPTYRDDITVYDVFDADGKQLAIFIADMYARESKRGGAWMNSYVSQSDLTGFKPVVAN
HLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKNYAKHYQNG
TPMPQALLDKVIAASKFNQGFATTEYLGAAMLDQNWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPPRYKTPYFSHI
MGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRANGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLSAQGG
DGATPEAPQSRP
>Mature_731_residues
TTRLAFALAASLGLAMPSYSIAAPAATQAATQANPFFADSTLPLHYPQFDKIKDSDFAPAFDAGMAEQLKEVEKIASQKA
KPSFDNTIIALEKSGATLDRATTVFFNLVGADTNDARKKLQADYSAKFAAHRDAISLNGKLFARIQTLYDQRAKLGLDAQ
GVRLVEKYYSDFVRDGAKLSDADKTTLKAMNAELANLGTTFSQNVLAEVNAAAVVVDDVKQLDGLSQEQIAAAAEAAKAR
KLDGKYVIALLNTTGQPPLTQLKNRELRKKIYDASVSRGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAAYSLENQTA
KTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQAKYNFDESQLKPYFELKNVL
ENGVFYAANQEYGLTFKQRTDLPTYRDDITVYDVFDADGKQLAIFIADMYARESKRGGAWMNSYVSQSDLTGFKPVVANH
LNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKNYAKHYQNGT
PMPQALLDKVIAASKFNQGFATTEYLGAAMLDQNWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPPRYKTPYFSHIM
GGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRANGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLSAQGGD
GATPEAPQSRP

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=667, Percent_Identity=29.0854572713643, Blast_Score=247, Evalue=3e-65,
Organism=Homo sapiens, GI14149738, Length=594, Percent_Identity=30.8080808080808, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI156105687, Length=599, Percent_Identity=24.7078464106845, Blast_Score=160, Evalue=5e-39,
Organism=Escherichia coli, GI1787819, Length=686, Percent_Identity=46.9387755102041, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=682, Percent_Identity=32.9912023460411, Blast_Score=338, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6319793, Length=593, Percent_Identity=26.3069139966273, Blast_Score=178, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6322715, Length=503, Percent_Identity=25.4473161033797, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20129717, Length=412, Percent_Identity=27.4271844660194, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21356111, Length=588, Percent_Identity=23.8095238095238, Blast_Score=152, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 80530; Mature: 80398

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRLAFALAASLGLAMPSYSIAAPAATQAATQANPFFADSTLPLHYPQFDKIKDSDFAP
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AFDAGMAEQLKEVEKIASQKAKPSFDNTIIALEKSGATLDRATTVFFNLVGADTNDARKK
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHH
LQADYSAKFAAHRDAISLNGKLFARIQTLYDQRAKLGLDAQGVRLVEKYYSDFVRDGAKL
HHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
SDADKTTLKAMNAELANLGTTFSQNVLAEVNAAAVVVDDVKQLDGLSQEQIAAAAEAAKA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEHHHHHHHCCCCHHHHHHHHHHHHH
RKLDGKYVIALLNTTGQPPLTQLKNRELRKKIYDASVSRGSHGGQYDNTALVARIMKLRA
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DKAKLLGFPTYAAYSLENQTAKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAA
CHHHHCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPTFKLEAWDWAYYSEKVRQAKYNFDESQLKPYFELKNVLENGVFYAANQEYGLTFKQR
CCCCEEEECCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCEEEEECCCCCCEECCC
TDLPTYRDDITVYDVFDADGKQLAIFIADMYARESKRGGAWMNSYVSQSDLTGFKPVVAN
CCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHCCCCCHHHHHHHCHHCCCCCCHHHHC
HLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVN
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EMWADEPSILKNYAKHYQNGTPMPQALLDKVIAASKFNQGFATTEYLGAAMLDQNWHQVS
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCC
ANQVPDAAGVMAFEAKALQQDGIAYAPVPPRYKTPYFSHIMGGYAAGYYAYIWSEVLDAN
CCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TQQWFKQHGGLSRANGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLSAQGG
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
DGATPEAPQSRP
CCCCCCCCCCCC
>Mature Secondary Structure 
TTRLAFALAASLGLAMPSYSIAAPAATQAATQANPFFADSTLPLHYPQFDKIKDSDFAP
CHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AFDAGMAEQLKEVEKIASQKAKPSFDNTIIALEKSGATLDRATTVFFNLVGADTNDARKK
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHH
LQADYSAKFAAHRDAISLNGKLFARIQTLYDQRAKLGLDAQGVRLVEKYYSDFVRDGAKL
HHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
SDADKTTLKAMNAELANLGTTFSQNVLAEVNAAAVVVDDVKQLDGLSQEQIAAAAEAAKA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEHHHHHHHCCCCHHHHHHHHHHHHH
RKLDGKYVIALLNTTGQPPLTQLKNRELRKKIYDASVSRGSHGGQYDNTALVARIMKLRA
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DKAKLLGFPTYAAYSLENQTAKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAA
CHHHHCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPTFKLEAWDWAYYSEKVRQAKYNFDESQLKPYFELKNVLENGVFYAANQEYGLTFKQR
CCCCEEEECCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCEEEEECCCCCCEECCC
TDLPTYRDDITVYDVFDADGKQLAIFIADMYARESKRGGAWMNSYVSQSDLTGFKPVVAN
CCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHCCCCCHHHHHHHCHHCCCCCCHHHHC
HLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVN
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EMWADEPSILKNYAKHYQNGTPMPQALLDKVIAASKFNQGFATTEYLGAAMLDQNWHQVS
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCC
ANQVPDAAGVMAFEAKALQQDGIAYAPVPPRYKTPYFSHIMGGYAAGYYAYIWSEVLDAN
CCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TQQWFKQHGGLSRANGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLSAQGG
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
DGATPEAPQSRP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]