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The map label for this gene is fhuA [H]

Identifier: 21242188

GI number: 21242188

Start: 1654973

End: 1657111

Strand: Reverse

Name: fhuA [H]

Synonym: XAC1435

Alternate gene names: 21242188

Gene position: 1657111-1654973 (Counterclockwise)

Preceding gene: 21242189

Following gene: 21242187

Centisome position: 32.02

GC content: 63.3

Gene sequence:

>2139_bases
ATGCGCCCCACGCTTCTTGTCACCGCGCTCGCCGCCGCGCTCGCTCTGCACACCCTGTCCGCCTTCGCTCAACACACCAC
CACGCCAGCCGTGACCGAGCTGGATGGCGTGGATGTCATCGGCCGTGCGCAGACGCTCTACAAGTCCGAAGACGCCGCTG
TTGCCACGCGCACCGATACCCCGCTGGCGCTGGTGCCGCAATCGGTGCAGGTGCTGCCGCGCGAGTTGATCGACGACCAG
GCCGCGCGGCAGATCACCGATCTGTATCGCAGCATCAGCGGCATCAGTTTCTTCAGCTATGCCGGTGTGACCTTGCGCGG
TTTCCGCCAGGAAAACGTGCTGTACGACGGTCTGCGCGGCGACCCGTATGCCGGGTTCTCGGTGCCGCAGCTGTTCAACA
TCGAACGCGTGGAAGTGCTCAAGGGTCCAGCCGGAGCGCTGTACGGCGGTGGCGAACCCGGGGGTGTGATCAACTATGTC
ACGCGCAAGCCCGGTCATCAGGCGGCGCGCCGCATCGAACTGCAGCTGGGCAATCAATCCTTCGGTGCAGCCTCCTTCGA
GGCCACCGGCCCTGCGCGCGAAGATGGCCGCATCCGTTACCGCATCGGCGCCTATGTCGATGGCGAAGACGGGTTTCGTT
GGAATACCGACAGCCAGAGCAAGATCGGCGATGCGTCGGTGGCCTTCGATCTGGGCGATACCGGCGAGCTCACCCTGCAA
TATACCGACATCACCCAGAACCTGGGCGGCAACCGACTGCGCGGCGTGCCGGTCGATAACGACGGCAACTTCCTCACCGA
CCGGCGCTGGAACCACAACGAACCTACCGATTTCCTGGACATGCGTGCCAAGGTGGCGCTTGCGCAGTATCGGTTTGCAC
CGTCCAGCGCGTGGGAGGTGGACATGGCGCTGCGTTGGTTCAAGAACCGAGAGCATCAGATCTATCACGAGCCGATGGGT
CTGATCGACCGCGATCGCGACGGCACCGCCGAATGGATGACCCGGCAGCTGCGCAATCAATACCGCGACAACGATGCGAT
CTCCAGCAACGTCAACGCGATATTCCGCACCAGTACCGGGGCGATCGAGCACAAGCTGCTGATGGGCGCGGACTACTACC
GGCTGGACGCGGATTTCCGCGCGCAAACCGCCAACACCGCAGACACCGGACGCGTGCGCGGCCCGGTGCCTGGCATCGAT
TTGTTCAACCCGGTATACGGCCGCAGCGGCTTCTACGATTACGGTTTGGATGCCCTGCCCTGGCGCGCCACCAGCACGCG
CAGTCAACGCTACGGCGCATATCTGCAGGACGAACTCACGCTGACGCCGCGCTGGTATGCAATGGCGGGGCTACGCTGGG
ACGGCTTCAAGGACGACAACCTGCTGGGTGGTTCGCGCGTCACCGGCAACGATGTCAGTTGGCGCGTCGGCAGCACCGTG
GTGTTACGCGATGGCATCAATGCCTACGCAAGCTATGCCAGCGGTTTCCTGCCGCAGGACGCGGCCAATCAGGACAGCAG
CGTGGGCGGACCGTTCGCTCCGGAACGCAGTACGCAATGGGAAATGGGCCTGAAGACTGCGCTCAACGATGGCGGACTCA
CCCTCAACACGGCGTTGTATCGCATCGAGCGCAGCAACATCGTGCAGGCGAACGGACGCGTCGTCGAGGGTGTCAATCAG
CTCTCTGCGCTTGGCTTGGTGCGCAGCGAAGGACTCGAAGTCGACCTGCTGGCCGACCTGACCGAGCGCTGGGTGCTCAA
TCTCACGTATGCCTACAACGATGCACGTGTGCTCGATGCAGGCACCAATGGCATCACCAATGCCTCTGGCGATCGCTTCG
CCAATGCACCGCGCAACACCTTCGGCCTGTGGACGCGCTACGACCTGCCGATGTGGCGCTCGGCGATCGCCTTCGGTGCC
GACTACGTGGGCGAACGCGTCAGCCTGGATGGCCAACGCGTCAAACCGTATGCCATTTACGACATCAGCTGGCAGACGCA
GTGGGACGCGTGGAAACTGCAGATCAACGTCAAGAACCTGTTCGACAAGGTCTATGCGGCGAGCGGGTTCAATACGCGCG
CCGGACACTTCCCCGGCGAGCCGCGTCGCATTTACGCGCAGCTGGCTTACAGCTTCTGA

Upstream 100 bases:

>100_bases
ATCCTCCACCAAGCATCGCGCCCGGCACCTCGGCGATCTCCGTGATCAAGCAACCACATCATGCTAAGATGCATTTGATA
ACCATTCCCATTAGTGACCA

Downstream 100 bases:

>100_bases
CGAGCGCGCGGCGAATATGTGGCGCGCCACCAGCCAGCTGCGATGGCAACGCAAACAGCGCATCGTGCCTGCGGTTGCCA
CCCGCTCAAATCACGTGTTT

Product: iron receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MRPTLLVTALAAALALHTLSAFAQHTTTPAVTELDGVDVIGRAQTLYKSEDAAVATRTDTPLALVPQSVQVLPRELIDDQ
AARQITDLYRSISGISFFSYAGVTLRGFRQENVLYDGLRGDPYAGFSVPQLFNIERVEVLKGPAGALYGGGEPGGVINYV
TRKPGHQAARRIELQLGNQSFGAASFEATGPAREDGRIRYRIGAYVDGEDGFRWNTDSQSKIGDASVAFDLGDTGELTLQ
YTDITQNLGGNRLRGVPVDNDGNFLTDRRWNHNEPTDFLDMRAKVALAQYRFAPSSAWEVDMALRWFKNREHQIYHEPMG
LIDRDRDGTAEWMTRQLRNQYRDNDAISSNVNAIFRTSTGAIEHKLLMGADYYRLDADFRAQTANTADTGRVRGPVPGID
LFNPVYGRSGFYDYGLDALPWRATSTRSQRYGAYLQDELTLTPRWYAMAGLRWDGFKDDNLLGGSRVTGNDVSWRVGSTV
VLRDGINAYASYASGFLPQDAANQDSSVGGPFAPERSTQWEMGLKTALNDGGLTLNTALYRIERSNIVQANGRVVEGVNQ
LSALGLVRSEGLEVDLLADLTERWVLNLTYAYNDARVLDAGTNGITNASGDRFANAPRNTFGLWTRYDLPMWRSAIAFGA
DYVGERVSLDGQRVKPYAIYDISWQTQWDAWKLQINVKNLFDKVYAASGFNTRAGHFPGEPRRIYAQLAYSF

Sequences:

>Translated_712_residues
MRPTLLVTALAAALALHTLSAFAQHTTTPAVTELDGVDVIGRAQTLYKSEDAAVATRTDTPLALVPQSVQVLPRELIDDQ
AARQITDLYRSISGISFFSYAGVTLRGFRQENVLYDGLRGDPYAGFSVPQLFNIERVEVLKGPAGALYGGGEPGGVINYV
TRKPGHQAARRIELQLGNQSFGAASFEATGPAREDGRIRYRIGAYVDGEDGFRWNTDSQSKIGDASVAFDLGDTGELTLQ
YTDITQNLGGNRLRGVPVDNDGNFLTDRRWNHNEPTDFLDMRAKVALAQYRFAPSSAWEVDMALRWFKNREHQIYHEPMG
LIDRDRDGTAEWMTRQLRNQYRDNDAISSNVNAIFRTSTGAIEHKLLMGADYYRLDADFRAQTANTADTGRVRGPVPGID
LFNPVYGRSGFYDYGLDALPWRATSTRSQRYGAYLQDELTLTPRWYAMAGLRWDGFKDDNLLGGSRVTGNDVSWRVGSTV
VLRDGINAYASYASGFLPQDAANQDSSVGGPFAPERSTQWEMGLKTALNDGGLTLNTALYRIERSNIVQANGRVVEGVNQ
LSALGLVRSEGLEVDLLADLTERWVLNLTYAYNDARVLDAGTNGITNASGDRFANAPRNTFGLWTRYDLPMWRSAIAFGA
DYVGERVSLDGQRVKPYAIYDISWQTQWDAWKLQINVKNLFDKVYAASGFNTRAGHFPGEPRRIYAQLAYSF
>Mature_712_residues
MRPTLLVTALAAALALHTLSAFAQHTTTPAVTELDGVDVIGRAQTLYKSEDAAVATRTDTPLALVPQSVQVLPRELIDDQ
AARQITDLYRSISGISFFSYAGVTLRGFRQENVLYDGLRGDPYAGFSVPQLFNIERVEVLKGPAGALYGGGEPGGVINYV
TRKPGHQAARRIELQLGNQSFGAASFEATGPAREDGRIRYRIGAYVDGEDGFRWNTDSQSKIGDASVAFDLGDTGELTLQ
YTDITQNLGGNRLRGVPVDNDGNFLTDRRWNHNEPTDFLDMRAKVALAQYRFAPSSAWEVDMALRWFKNREHQIYHEPMG
LIDRDRDGTAEWMTRQLRNQYRDNDAISSNVNAIFRTSTGAIEHKLLMGADYYRLDADFRAQTANTADTGRVRGPVPGID
LFNPVYGRSGFYDYGLDALPWRATSTRSQRYGAYLQDELTLTPRWYAMAGLRWDGFKDDNLLGGSRVTGNDVSWRVGSTV
VLRDGINAYASYASGFLPQDAANQDSSVGGPFAPERSTQWEMGLKTALNDGGLTLNTALYRIERSNIVQANGRVVEGVNQ
LSALGLVRSEGLEVDLLADLTERWVLNLTYAYNDARVLDAGTNGITNASGDRFANAPRNTFGLWTRYDLPMWRSAIAFGA
DYVGERVSLDGQRVKPYAIYDISWQTQWDAWKLQINVKNLFDKVYAASGFNTRAGHFPGEPRRIYAQLAYSF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=794, Percent_Identity=23.2997481108312, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787344, Length=771, Percent_Identity=24.3839169909209, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1787024, Length=711, Percent_Identity=23.0661040787623, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78990; Mature: 78990

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTLLVTALAAALALHTLSAFAQHTTTPAVTELDGVDVIGRAQTLYKSEDAAVATRTDT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCEEEEECCC
PLALVPQSVQVLPRELIDDQAARQITDLYRSISGISFFSYAGVTLRGFRQENVLYDGLRG
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCEEEECCCCCCCEEECCCC
DPYAGFSVPQLFNIERVEVLKGPAGALYGGGEPGGVINYVTRKPGHQAARRIELQLGNQS
CCCCCCCCCHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHEEEEEECCCC
FGAASFEATGPAREDGRIRYRIGAYVDGEDGFRWNTDSQSKIGDASVAFDLGDTGELTLQ
CCCCEECCCCCCCCCCEEEEEEEEEEECCCCCEECCCCCCCCCCCEEEEECCCCCEEEEE
YTDITQNLGGNRLRGVPVDNDGNFLTDRRWNHNEPTDFLDMRAKVALAQYRFAPSSAWEV
EEEHHHCCCCCEEECEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCH
DMALRWFKNREHQIYHEPMGLIDRDRDGTAEWMTRQLRNQYRDNDAISSNVNAIFRTSTG
HHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
AIEHKLLMGADYYRLDADFRAQTANTADTGRVRGPVPGIDLFNPVYGRSGFYDYGLDALP
CHHEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WRATSTRSQRYGAYLQDELTLTPRWYAMAGLRWDGFKDDNLLGGSRVTGNDVSWRVGSTV
CCCCCCCHHHCCCEEECCEEECCCHHEEECCEECCCCCCCCCCCCEECCCCCEEECCCEE
VLRDGINAYASYASGFLPQDAANQDSSVGGPFAPERSTQWEMGLKTALNDGGLTLNTALY
EEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHEEE
RIERSNIVQANGRVVEGVNQLSALGLVRSEGLEVDLLADLTERWVLNLTYAYNDARVLDA
EEECCCEEECCCEEEHHHHHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEEEECCCEEEEC
GTNGITNASGDRFANAPRNTFGLWTRYDLPMWRSAIAFGADYVGERVSLDGQRVKPYAIY
CCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCHHHCCCEECCCCCCCCCEEEE
DISWQTQWDAWKLQINVKNLFDKVYAASGFNTRAGHFPGEPRRIYAQLAYSF
EECEEECCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEHHCC
>Mature Secondary Structure
MRPTLLVTALAAALALHTLSAFAQHTTTPAVTELDGVDVIGRAQTLYKSEDAAVATRTDT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCEEEEECCC
PLALVPQSVQVLPRELIDDQAARQITDLYRSISGISFFSYAGVTLRGFRQENVLYDGLRG
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCEEEECCCCCCCEEECCCC
DPYAGFSVPQLFNIERVEVLKGPAGALYGGGEPGGVINYVTRKPGHQAARRIELQLGNQS
CCCCCCCCCHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHEEEEEECCCC
FGAASFEATGPAREDGRIRYRIGAYVDGEDGFRWNTDSQSKIGDASVAFDLGDTGELTLQ
CCCCEECCCCCCCCCCEEEEEEEEEEECCCCCEECCCCCCCCCCCEEEEECCCCCEEEEE
YTDITQNLGGNRLRGVPVDNDGNFLTDRRWNHNEPTDFLDMRAKVALAQYRFAPSSAWEV
EEEHHHCCCCCEEECEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCH
DMALRWFKNREHQIYHEPMGLIDRDRDGTAEWMTRQLRNQYRDNDAISSNVNAIFRTSTG
HHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
AIEHKLLMGADYYRLDADFRAQTANTADTGRVRGPVPGIDLFNPVYGRSGFYDYGLDALP
CHHEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WRATSTRSQRYGAYLQDELTLTPRWYAMAGLRWDGFKDDNLLGGSRVTGNDVSWRVGSTV
CCCCCCCHHHCCCEEECCEEECCCHHEEECCEECCCCCCCCCCCCEECCCCCEEECCCEE
VLRDGINAYASYASGFLPQDAANQDSSVGGPFAPERSTQWEMGLKTALNDGGLTLNTALY
EEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHEEE
RIERSNIVQANGRVVEGVNQLSALGLVRSEGLEVDLLADLTERWVLNLTYAYNDARVLDA
EEECCCEEECCCEEEHHHHHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEEEECCCEEEEC
GTNGITNASGDRFANAPRNTFGLWTRYDLPMWRSAIAFGADYVGERVSLDGQRVKPYAIY
CCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCHHHCCCEECCCCCCCCCEEEE
DISWQTQWDAWKLQINVKNLFDKVYAASGFNTRAGHFPGEPRRIYAQLAYSF
EECEEECCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]