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The map label for this gene is cdsA [H]

Identifier: 21242169

GI number: 21242169

Start: 1631539

End: 1632366

Strand: Reverse

Name: cdsA [H]

Synonym: XAC1416

Alternate gene names: 21242169

Gene position: 1632366-1631539 (Counterclockwise)

Preceding gene: 21242170

Following gene: 21242168

Centisome position: 31.54

GC content: 67.15

Gene sequence:

>828_bases
ATGACCAAGACTCGCGTGATTGCCGCGCTGATCATGGCGCCGCTCGCGATTTGCGCGATCGTGCTGCTGCCCACCCAATG
GCTGGCAGCGCTGGCGGCGGTCCTGTTCCTGACCGGTCTGTGGGAGTGGCTCAAGCTCTCCGGCATCGACGACAGCCTGC
CGCGCACCGTGCTGCTGATGCTCAATCTGCTGCTGATGGTGCTGATGGTGTGGGCCTCGGCCGGCTCCATGGTGCTGTTC
CAGATTGCGTCGCTGGTGGGCGTGGCGTGGTGGCTGTTGGCGCTGCTGTGGCTGCGTTTTTTCACCTTCGGTGCCGATCA
TGGCAACGGCCAGGCGCGCGCACTCAAGCTGGCCGCCGGCACCCTGGCAGTGCTGCCGGCGTGGGCGGCGCTGGTGCTGC
TGCATGCCAGCCCGGACAAGGGCAACCTGTGGTTGCTGACCGCGCTGACCATGGTGTGGGCGGCTGACTCCGGCGCCTAT
TTCGCTGGCCGCGCGTTCGGCAAGCACAAGCTGGCGCCGCGGGTCAGCCCCAACAAGACCATCGAAGGGTTGCTCGGAGG
CCTGCTCGCCGGCATTGCGGTTGCCTGCGCGTTCGGCTGGCTGGCCGGGCTGACGCTGGCACATGTGCCGCAGCTGGTGC
TGGTCTCCGCACTGGCAGTGCTGGCATCGGTGCTGGGCGACCTGTTCGAAAGCCTGCTCAAGCGCCACGCCGGCGCCAAG
GACTCGGGCACGCTGATTCCGGGCCATGGCGGCGTACTGGACCGCATCGATGGCGTGCTCGCTGCCCTGCCGGTGTTCGC
ACTCGGCAAGGAAATTCTCGGATTCTAG

Upstream 100 bases:

>100_bases
GCGTGCTGCAGCAAGCGCTGGACGACTATGCCGGGCGTGAACGTCGCTTCGGCCTGACCAGCGCACAGATCGCCGACAAG
GCGACGGAGAGCTCCTCCGC

Downstream 100 bases:

>100_bases
GCATGGCTGGCTCCTCTCCCCGTCAGGTCGCCGTGTTCGGCGCCACCGGCTCGATCGGCACATCGGCGCTGGACGTGATC
GCCCGCCACCCCGAGCGGCT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTKTRVIAALIMAPLAICAIVLLPTQWLAALAAVLFLTGLWEWLKLSGIDDSLPRTVLLMLNLLLMVLMVWASAGSMVLF
QIASLVGVAWWLLALLWLRFFTFGADHGNGQARALKLAAGTLAVLPAWAALVLLHASPDKGNLWLLTALTMVWAADSGAY
FAGRAFGKHKLAPRVSPNKTIEGLLGGLLAGIAVACAFGWLAGLTLAHVPQLVLVSALAVLASVLGDLFESLLKRHAGAK
DSGTLIPGHGGVLDRIDGVLAALPVFALGKEILGF

Sequences:

>Translated_275_residues
MTKTRVIAALIMAPLAICAIVLLPTQWLAALAAVLFLTGLWEWLKLSGIDDSLPRTVLLMLNLLLMVLMVWASAGSMVLF
QIASLVGVAWWLLALLWLRFFTFGADHGNGQARALKLAAGTLAVLPAWAALVLLHASPDKGNLWLLTALTMVWAADSGAY
FAGRAFGKHKLAPRVSPNKTIEGLLGGLLAGIAVACAFGWLAGLTLAHVPQLVLVSALAVLASVLGDLFESLLKRHAGAK
DSGTLIPGHGGVLDRIDGVLAALPVFALGKEILGF
>Mature_274_residues
TKTRVIAALIMAPLAICAIVLLPTQWLAALAAVLFLTGLWEWLKLSGIDDSLPRTVLLMLNLLLMVLMVWASAGSMVLFQ
IASLVGVAWWLLALLWLRFFTFGADHGNGQARALKLAAGTLAVLPAWAALVLLHASPDKGNLWLLTALTMVWAADSGAYF
AGRAFGKHKLAPRVSPNKTIEGLLGGLLAGIAVACAFGWLAGLTLAHVPQLVLVSALAVLASVLGDLFESLLKRHAGAKD
SGTLIPGHGGVLDRIDGVLAALPVFALGKEILGF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=277, Percent_Identity=42.5992779783394, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=41.5929203539823, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28919; Mature: 28788

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKTRVIAALIMAPLAICAIVLLPTQWLAALAAVLFLTGLWEWLKLSGIDDSLPRTVLLM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LNLLLMVLMVWASAGSMVLFQIASLVGVAWWLLALLWLRFFTFGADHGNGQARALKLAAG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TLAVLPAWAALVLLHASPDKGNLWLLTALTMVWAADSGAYFAGRAFGKHKLAPRVSPNKT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHH
IEGLLGGLLAGIAVACAFGWLAGLTLAHVPQLVLVSALAVLASVLGDLFESLLKRHAGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSGTLIPGHGGVLDRIDGVLAALPVFALGKEILGF
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]