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The map label for this gene is fabZ

Identifier: 21242163

GI number: 21242163

Start: 1624658

End: 1625116

Strand: Reverse

Name: fabZ

Synonym: XAC1410

Alternate gene names: 21242163

Gene position: 1625116-1624658 (Counterclockwise)

Preceding gene: 21242164

Following gene: 21242162

Centisome position: 31.4

GC content: 60.35

Gene sequence:

>459_bases
ATGAGCCACCACGTTTACGAACTGCCGATCGACGTCAGTCAGATCCAGACGCTGCTCCCGCACCGTTACCCGTTTCTGCT
GGTCGACCGCATCCTCGAACTCGATCTTGAAACCAAGTGGATCGTGGCGCAGAAGAACGTCAGCATCAACGAGCCGTTCT
TCCAGGGCCATTTTCCGAACCGTCCGGTCATGCCTGGCGTGCTGATCATCGAGGCGCTGGCGCAGGTCGGCGGCGTAATG
ACCCAGCTCGGCCTGGGCCGCGATGCCTTGTCGCAGCTGTTCTATATGGTCAAGGTGGACAAGGCCCGCTTCAACAAGCA
GGTGGTGCCGGGCGACGTGTTGATCATGGAAGTGCAGATGAAGCGCCTGATCCGCAACGTGGGATGCTTCTACGGCGAAG
CCAAGGTCGATGGCGAAGTGGTGGCCAGTGCCGAGGTGATGTGCGCCGGCGCCAGGTAA

Upstream 100 bases:

>100_bases
CCCCTCTCACCGACAATCGCACGTGGCGCAAAAACGCCGCGCGCTTCAAGCAGCTTGATGTGCTCGCTAGGCGCATCCTG
GCTGTGGGCAAGGAGAAAGA

Downstream 100 bases:

>100_bases
TCACCCGCTTTCGGAGTAAGACACGATGCGCGATTCAACACCTTTGATTCATCCGACGGCGGTCATCGATCCATCGGCAA
CGCTGGCGGACGACGTGCGC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSHHVYELPIDVSQIQTLLPHRYPFLLVDRILELDLETKWIVAQKNVSINEPFFQGHFPNRPVMPGVLIIEALAQVGGVM
TQLGLGRDALSQLFYMVKVDKARFNKQVVPGDVLIMEVQMKRLIRNVGCFYGEAKVDGEVVASAEVMCAGAR

Sequences:

>Translated_152_residues
MSHHVYELPIDVSQIQTLLPHRYPFLLVDRILELDLETKWIVAQKNVSINEPFFQGHFPNRPVMPGVLIIEALAQVGGVM
TQLGLGRDALSQLFYMVKVDKARFNKQVVPGDVLIMEVQMKRLIRNVGCFYGEAKVDGEVVASAEVMCAGAR
>Mature_151_residues
SHHVYELPIDVSQIQTLLPHRYPFLLVDRILELDLETKWIVAQKNVSINEPFFQGHFPNRPVMPGVLIIEALAQVGGVMT
QLGLGRDALSQLFYMVKVDKARFNKQVVPGDVLIMEVQMKRLIRNVGCFYGEAKVDGEVVASAEVMCAGAR

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=49.6503496503497, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_XANAC (Q8PML6)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641745.1
- ProteinModelPortal:   Q8PML6
- SMR:   Q8PML6
- GeneID:   1155481
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1410
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   XAXO190486:XAC1410-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17064; Mature: 16933

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: ACT_SITE 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHHVYELPIDVSQIQTLLPHRYPFLLVDRILELDLETKWIVAQKNVSINEPFFQGHFPN
CCCCEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
RPVMPGVLIIEALAQVGGVMTQLGLGRDALSQLFYMVKVDKARFNKQVVPGDVLIMEVQM
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
KRLIRNVGCFYGEAKVDGEVVASAEVMCAGAR
HHHHHHHHHHCCCCCCCCCEEECEEEEEECCC
>Mature Secondary Structure 
SHHVYELPIDVSQIQTLLPHRYPFLLVDRILELDLETKWIVAQKNVSINEPFFQGHFPN
CCCEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
RPVMPGVLIIEALAQVGGVMTQLGLGRDALSQLFYMVKVDKARFNKQVVPGDVLIMEVQM
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
KRLIRNVGCFYGEAKVDGEVVASAEVMCAGAR
HHHHHHHHHHCCCCCCCCCEEECEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217