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The map label for this gene is cfa [H]

Identifier: 21242125

GI number: 21242125

Start: 1580576

End: 1581646

Strand: Reverse

Name: cfa [H]

Synonym: XAC1372

Alternate gene names: 21242125

Gene position: 1581646-1580576 (Counterclockwise)

Preceding gene: 21242126

Following gene: 77748581

Centisome position: 30.56

GC content: 65.45

Gene sequence:

>1071_bases
ATGTCTACCGTTACCGTCCCGCCCTCCGCGCAGCCTGAAGAAGCCTTCGCCACGCGGCTCGCCGAATCCGGTGTGCTGCC
CGATGCCGTCTTGCGCCACGGCATCCGTCGCCTGTGCGCGCAGCGCCTGCGCGATGAGCGCGGCAACGATGCCGATGTCA
ACGGCGAGCGGCAGCGCGCCTTCATCGACAGCCTGCGGGCCAGCGCGATCGCGATCGAAACCGATGCGGCCAATCGCCAG
CATTACGAATTGCCGCCGCAGTTCTTCACCCTGTGCCTGGGCCGCCGGCTCAAGTACAGCAGCTGCTATTGGGACGCCAC
CACGCCCAATCTGGATGCCGCCGAAGAACGCATGCTGGCGCTGTACGGCGAGCGCGCCGAACTGGCCGATGGTCAACGCA
TCCTGGAACTGGGCTGCGGCTGGGGCTCGTTGACCCTGTGGATGGCCGAGCGCTATCCGAACGCCAGCATCACGGCGGTC
TCCAACTCGCGCCCGCAGCGCGCGCACATTCTGGAGCAGTGTCGCGTGCGCGGGCTGAGCAACGTGCAGGTGATCACTGC
CGACGTCAACGCGCTGACCCTGCCATCGGGCGACTTCGACCGCGTGGTCTCGGTGGAGATGTTCGAGCACATGCGCAACT
ACCGCGACCTGCTCGCACGCGTCGGCAGCTGGCTGGCACCGGGCGGCAAGCTGTTCGTGCACATTTTTTGCCACCGTGAT
CTGGCCTACCCGTTCGAAGTGGCCGGCGAAGACAACTGGATGGGCCGGCATTTCTTTACCGGCGGGCTGATGCCGGCTGC
CGATACCCTGCTGCATTTCCAGCAGGACGTGGTGATCGAACAACGCTGGCTGCTGTCGGGCGAGCATTACGAGAAGACCG
CCAACGCCTGGCTGGAAAACCAGGACCGCCACCGCGACCAGATCATGCCGCTGTTGAAGCAGACCTACGGCGACGACGCG
CAGCGTTGGTGGCAGCGCTGGCGGATGTTCTGGCTGGCCTGCGCGGAATTGTTCGGCTACGACCAGGGCCGCGAATGGGG
CGTGGCGCACTACCGTTTCGTCAAACGTTGA

Upstream 100 bases:

>100_bases
AGGCGCTGCGCTCGCGTGGCGAGGACTATGCGCAGTACCAGCGCAGCACCAGCGCGTTCTTTCCACTTCCCCCTTCGTCC
TGAGTTGCCTGGAGAGTTGC

Downstream 100 bases:

>100_bases
CTGCACCGCCGGCAGTTGTTGCGACCATGACTGCCGGCCACCCTTGCACCACGCGTACGTGCGCGCACCGCGACAACCGC
GCAGCAGTCACTTGGTTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSTVTVPPSAQPEEAFATRLAESGVLPDAVLRHGIRRLCAQRLRDERGNDADVNGERQRAFIDSLRASAIAIETDAANRQ
HYELPPQFFTLCLGRRLKYSSCYWDATTPNLDAAEERMLALYGERAELADGQRILELGCGWGSLTLWMAERYPNASITAV
SNSRPQRAHILEQCRVRGLSNVQVITADVNALTLPSGDFDRVVSVEMFEHMRNYRDLLARVGSWLAPGGKLFVHIFCHRD
LAYPFEVAGEDNWMGRHFFTGGLMPAADTLLHFQQDVVIEQRWLLSGEHYEKTANAWLENQDRHRDQIMPLLKQTYGDDA
QRWWQRWRMFWLACAELFGYDQGREWGVAHYRFVKR

Sequences:

>Translated_356_residues
MSTVTVPPSAQPEEAFATRLAESGVLPDAVLRHGIRRLCAQRLRDERGNDADVNGERQRAFIDSLRASAIAIETDAANRQ
HYELPPQFFTLCLGRRLKYSSCYWDATTPNLDAAEERMLALYGERAELADGQRILELGCGWGSLTLWMAERYPNASITAV
SNSRPQRAHILEQCRVRGLSNVQVITADVNALTLPSGDFDRVVSVEMFEHMRNYRDLLARVGSWLAPGGKLFVHIFCHRD
LAYPFEVAGEDNWMGRHFFTGGLMPAADTLLHFQQDVVIEQRWLLSGEHYEKTANAWLENQDRHRDQIMPLLKQTYGDDA
QRWWQRWRMFWLACAELFGYDQGREWGVAHYRFVKR
>Mature_355_residues
STVTVPPSAQPEEAFATRLAESGVLPDAVLRHGIRRLCAQRLRDERGNDADVNGERQRAFIDSLRASAIAIETDAANRQH
YELPPQFFTLCLGRRLKYSSCYWDATTPNLDAAEERMLALYGERAELADGQRILELGCGWGSLTLWMAERYPNASITAVS
NSRPQRAHILEQCRVRGLSNVQVITADVNALTLPSGDFDRVVSVEMFEHMRNYRDLLARVGSWLAPGGKLFVHIFCHRDL
AYPFEVAGEDNWMGRHFFTGGLMPAADTLLHFQQDVVIEQRWLLSGEHYEKTANAWLENQDRHRDQIMPLLKQTYGDDAQ
RWWQRWRMFWLACAELFGYDQGREWGVAHYRFVKR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=223, Percent_Identity=30.4932735426009, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI133904226, Length=285, Percent_Identity=23.859649122807, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 40920; Mature: 40789

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVTVPPSAQPEEAFATRLAESGVLPDAVLRHGIRRLCAQRLRDERGNDADVNGERQRA
CCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FIDSLRASAIAIETDAANRQHYELPPQFFTLCLGRRLKYSSCYWDATTPNLDAAEERMLA
HHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
LYGERAELADGQRILELGCGWGSLTLWMAERYPNASITAVSNSRPQRAHILEQCRVRGLS
HHCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCC
NVQVITADVNALTLPSGDFDRVVSVEMFEHMRNYRDLLARVGSWLAPGGKLFVHIFCHRD
CCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
LAYPFEVAGEDNWMGRHFFTGGLMPAADTLLHFQQDVVIEQRWLLSGEHYEKTANAWLEN
CCCCEEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
QDRHRDQIMPLLKQTYGDDAQRWWQRWRMFWLACAELFGYDQGREWGVAHYRFVKR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
STVTVPPSAQPEEAFATRLAESGVLPDAVLRHGIRRLCAQRLRDERGNDADVNGERQRA
CEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FIDSLRASAIAIETDAANRQHYELPPQFFTLCLGRRLKYSSCYWDATTPNLDAAEERMLA
HHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
LYGERAELADGQRILELGCGWGSLTLWMAERYPNASITAVSNSRPQRAHILEQCRVRGLS
HHCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCC
NVQVITADVNALTLPSGDFDRVVSVEMFEHMRNYRDLLARVGSWLAPGGKLFVHIFCHRD
CCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
LAYPFEVAGEDNWMGRHFFTGGLMPAADTLLHFQQDVVIEQRWLLSGEHYEKTANAWLEN
CCCCEEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
QDRHRDQIMPLLKQTYGDDAQRWWQRWRMFWLACAELFGYDQGREWGVAHYRFVKR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]