Click here to switch to the map view.

The map label for this gene is ileS

Identifier: 21242008

GI number: 21242008

Start: 1430692

End: 1433523

Strand: Direct

Name: ileS

Synonym: XAC1254

Alternate gene names: 21242008

Gene position: 1430692-1433523 (Clockwise)

Preceding gene: 21242007

Following gene: 21242009

Centisome position: 27.64

GC content: 66.1

Gene sequence:

>2832_bases
GTGACCCAAGATTACAAAGCCACTCTTCATCTGCCTGCGACGGAATTTCCGATGCGCGGCGACCTGCCCAAGCGCGAGCC
GGCGATGCTGGAGCGCTGGGAGCGCGAGGGCTTCTACGCGCAACTGCGTGCCAATGCCGCGGGGCGGCCGCTGTTCGTGC
TGCATGACGGCCCGCCGTATGCGAACGGCCAGATCCACCTCGGCCATGCGGTCAACAAGATCCTCAAGGACATCATCGTC
AAGTCGAAATATCTGGCCGGCTTCGATGCACCGTATATCCCGGGCTGGGATTGCCATGGCCTGCCGATCGAGATCGCGAT
CGAAAAAAAATACGGCAAGGTCGGCGTCAAGCTCGATGCGGCCGAATTTCGGCAGAAGTGCCGCGAATACGCCACCGAGC
AGATCGATCTGCAGCGGCGCGATTTCAAGCGCCTGGGCGTGATCGGCGATTGGGACAACCCATACAAGACGCTGGATTTC
CGCTTCGAAGCCAACGAAATCCGCGCGCTGGCCAAGGTGGTCGATAACGGCCACCTGACCCGCGGCGTCAAGCCGGTGCA
CTGGTGCTTCGATTGCGGTTCGGCGCTGGCCGAGGCCGAGATCGAATACGCCGACAAGGTGTCGCCGACCGTGGATATCG
CCTATCCGGCGCGCGACCCGGCTGCGGTCGCTGCTGCGTTCGGCGCGAGCCTGCCGGCGGGCGTGGGCGTGGCGGTGCCG
ATCTGGACCACCACGCCGTGGACGCTGCCGGCGTCGCTGGCGGTGAGCCTGGGCGCGGAGCTGGACTATGTGCTGGTCGA
AGGTCCGGCCGATCGCGGCCAGCCGCGCTGGCTGGTGATCGCCGAAGCGTTGGCTGCCAAGGCGCTGGCGCGGTACGGCG
TGGGCGAAGTCGTGGTGCATGGGCACGCCAAGGGCGCGGCGCTGGAGCACATGCTGCTGAATCACCCGTTCTATGCCGAA
CGCGAGATCCCGCTGCTGCTGGGCGACCACGTGTCGGCCGAGGATGGTACCGGCGCGGTGCATACGGCACCCGGCCACGG
CCAGGAGGACTATCAGGTCTCCAAGCAATACGGGCTGCTGGAGCGCTACGGCGCTGCGCAGATCAATCCGGTGGACGGGC
GCGGCGTGTATCTGCCGTCGACCCCGCCGCTGCGCGACACCGTGCTGGCCGGGCTGCATATCTGGAAGGCGAACGACGTC
ATCATCGAAGCGCTGCGCGAGACCGGCGTGCTGCTGGCGGCCAGCAAGATGGAGCACAGCTACCCGCATTGCTGGCGCCA
CAAGACGCCGATTGCGTTCCGTGCCACGCCGCAGTGGTTCATCTCGATGGAGCAGGCCAACCTGCGTGCCGATGCGCTCA
AGGCCATCGAAAACGTGCATTGGTATCCGTCCTGGGGCCAGGCGCGTATCGCCGGCATGGTCGACGGGCGCCCGGACTGG
ACCATCTCGCGGCAGCGCACCTGGGGCGTGCCGATCGCCTTGTTCGTGCATCGCGAAACCGGCGAGCCGCATCCGCGCAG
CACCGAGTTGCTGCGCCAGGTCGCCGACCGCGTGGAGCAGGGCGGCGTGGATGTCTGGTACACGCTGGACGCGTCCGAGC
TGCTGAGTAGCGAGGCCGCAGATTACGAGAAGATCACCGACATCCTGGATGTGTGGTTCGACTCCGGCGTGACGCACGAA
GCGGTGCTTCCGGATCGTGGGCTGCCCAAGCCGGCCGACCTGTATCTGGAGGGTTCCGATCAGCATCGCGGCTGGTTCCA
GTCGTCGCTGCTGAGCGGCGTGGCGATGGACAAGGCGGCGCCCTACAAGCAGTGCCTGACCCACGGTTTTACCGTGGACG
AGCACGGCCGCAAGATGTCCAAGTCGCTGGGCAACGGCATCGAGCCGCAGGACATCATGAAGACGCTGGGCGCGGACATC
CTGCGCCTGTGGATCGCCTCGGCCGACTACAGCAACGAGATGTCGCTGTCGCAGGAGATCCTCAAGCGCAACGCCGATGC
CTACCGCCGCCTGCGCAATACCGCGCGCTTCCTGCTCGGTAACCTGCATGGCTTCGATCCGCTGCAGCACCTGGTGGCGC
TGGACGAGATGGTGCTGCTGGACCGCTGGATCGTGCATCGCGCGCACGAGCTGCAGGAAAAGATCGTGGCCGCCTACGCG
CGCTACGACTTCGCCGAGATCGTGCAGGCACTGCTGAACTTCTGCAGCGTGGACCTGGGCTCGCTGTACCTGGATGTCAC
CAAGGACCGCCTGTACACGATGGCCGAAGACGCGCGCGGCCGCCGGTCGGCGCAGAGCGCGATGTACCACGTGGCCGAGG
CGTTCGTGCGCTGGATCGCGCCGGTATTGAGCTTCACTGCCGAGGAACTGTGGGGCTACCTGCCGGGCAAGCATGTCGAC
AACGTGCTCTTCGCCACCTGGTACGACGGCCTTGCGCCGTTGCCGGCCGACGCTGCGTTGAGCGGTGCGGATTTCGACAA
GTTGCTGGTCCTGCGCGAGCAGGTGGCCAAGGTGCTGGAGCCGATGCGTGCCAATGGCGCGATCGGTGCGGCGCTGGAAG
CGGAAATCACCGTGGCCGCCGATGCGCAGACCGCTGCGCGCTGGCAGCCGCTGGCCGAGGAACTGCGCTTCTTGTTCATC
AGTGGCGACGTCACCGTGACCGCGGCCAGTACCGACGACATTTTCGTCAGTGCGCAGCCCACGACCAAGGCCAAGTGCGT
GCGCTGCTGGCACCACCAGGCCAGCGTGGGCAGCGACCCGCGTCACCCGGAACTGTGCAGCCGTTGCGTCAGCAATATCG
AAGGTCCGGGCGAGCGGCGTCGCTGGTTCTGA

Upstream 100 bases:

>100_bases
GCGTTCTGAGCAACAACCCTCGACTACGGCGAGTCCCTCGCAAGAGCCCGCACGTCCATGTGCGGACTTCTCAAGCAATC
CAGCGCAACGGTAGGTTCCT

Downstream 100 bases:

>100_bases
GGCCGCCTCGCCGGCGGCGCGTGGCAGGGACCTGGCCACGCACTGCCGGCGTCTGGCGCTGGCGCAGTCCGCGTCAGACG
CCGGGGTAGCCCTGGTTGCT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 943; Mature: 942

Protein sequence:

>943_residues
MTQDYKATLHLPATEFPMRGDLPKREPAMLERWEREGFYAQLRANAAGRPLFVLHDGPPYANGQIHLGHAVNKILKDIIV
KSKYLAGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVKLDAAEFRQKCREYATEQIDLQRRDFKRLGVIGDWDNPYKTLDF
RFEANEIRALAKVVDNGHLTRGVKPVHWCFDCGSALAEAEIEYADKVSPTVDIAYPARDPAAVAAAFGASLPAGVGVAVP
IWTTTPWTLPASLAVSLGAELDYVLVEGPADRGQPRWLVIAEALAAKALARYGVGEVVVHGHAKGAALEHMLLNHPFYAE
REIPLLLGDHVSAEDGTGAVHTAPGHGQEDYQVSKQYGLLERYGAAQINPVDGRGVYLPSTPPLRDTVLAGLHIWKANDV
IIEALRETGVLLAASKMEHSYPHCWRHKTPIAFRATPQWFISMEQANLRADALKAIENVHWYPSWGQARIAGMVDGRPDW
TISRQRTWGVPIALFVHRETGEPHPRSTELLRQVADRVEQGGVDVWYTLDASELLSSEAADYEKITDILDVWFDSGVTHE
AVLPDRGLPKPADLYLEGSDQHRGWFQSSLLSGVAMDKAAPYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMKTLGADI
LRLWIASADYSNEMSLSQEILKRNADAYRRLRNTARFLLGNLHGFDPLQHLVALDEMVLLDRWIVHRAHELQEKIVAAYA
RYDFAEIVQALLNFCSVDLGSLYLDVTKDRLYTMAEDARGRRSAQSAMYHVAEAFVRWIAPVLSFTAEELWGYLPGKHVD
NVLFATWYDGLAPLPADAALSGADFDKLLVLREQVAKVLEPMRANGAIGAALEAEITVAADAQTAARWQPLAEELRFLFI
SGDVTVTAASTDDIFVSAQPTTKAKCVRCWHHQASVGSDPRHPELCSRCVSNIEGPGERRRWF

Sequences:

>Translated_943_residues
MTQDYKATLHLPATEFPMRGDLPKREPAMLERWEREGFYAQLRANAAGRPLFVLHDGPPYANGQIHLGHAVNKILKDIIV
KSKYLAGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVKLDAAEFRQKCREYATEQIDLQRRDFKRLGVIGDWDNPYKTLDF
RFEANEIRALAKVVDNGHLTRGVKPVHWCFDCGSALAEAEIEYADKVSPTVDIAYPARDPAAVAAAFGASLPAGVGVAVP
IWTTTPWTLPASLAVSLGAELDYVLVEGPADRGQPRWLVIAEALAAKALARYGVGEVVVHGHAKGAALEHMLLNHPFYAE
REIPLLLGDHVSAEDGTGAVHTAPGHGQEDYQVSKQYGLLERYGAAQINPVDGRGVYLPSTPPLRDTVLAGLHIWKANDV
IIEALRETGVLLAASKMEHSYPHCWRHKTPIAFRATPQWFISMEQANLRADALKAIENVHWYPSWGQARIAGMVDGRPDW
TISRQRTWGVPIALFVHRETGEPHPRSTELLRQVADRVEQGGVDVWYTLDASELLSSEAADYEKITDILDVWFDSGVTHE
AVLPDRGLPKPADLYLEGSDQHRGWFQSSLLSGVAMDKAAPYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMKTLGADI
LRLWIASADYSNEMSLSQEILKRNADAYRRLRNTARFLLGNLHGFDPLQHLVALDEMVLLDRWIVHRAHELQEKIVAAYA
RYDFAEIVQALLNFCSVDLGSLYLDVTKDRLYTMAEDARGRRSAQSAMYHVAEAFVRWIAPVLSFTAEELWGYLPGKHVD
NVLFATWYDGLAPLPADAALSGADFDKLLVLREQVAKVLEPMRANGAIGAALEAEITVAADAQTAARWQPLAEELRFLFI
SGDVTVTAASTDDIFVSAQPTTKAKCVRCWHHQASVGSDPRHPELCSRCVSNIEGPGERRRWF
>Mature_942_residues
TQDYKATLHLPATEFPMRGDLPKREPAMLERWEREGFYAQLRANAAGRPLFVLHDGPPYANGQIHLGHAVNKILKDIIVK
SKYLAGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVKLDAAEFRQKCREYATEQIDLQRRDFKRLGVIGDWDNPYKTLDFR
FEANEIRALAKVVDNGHLTRGVKPVHWCFDCGSALAEAEIEYADKVSPTVDIAYPARDPAAVAAAFGASLPAGVGVAVPI
WTTTPWTLPASLAVSLGAELDYVLVEGPADRGQPRWLVIAEALAAKALARYGVGEVVVHGHAKGAALEHMLLNHPFYAER
EIPLLLGDHVSAEDGTGAVHTAPGHGQEDYQVSKQYGLLERYGAAQINPVDGRGVYLPSTPPLRDTVLAGLHIWKANDVI
IEALRETGVLLAASKMEHSYPHCWRHKTPIAFRATPQWFISMEQANLRADALKAIENVHWYPSWGQARIAGMVDGRPDWT
ISRQRTWGVPIALFVHRETGEPHPRSTELLRQVADRVEQGGVDVWYTLDASELLSSEAADYEKITDILDVWFDSGVTHEA
VLPDRGLPKPADLYLEGSDQHRGWFQSSLLSGVAMDKAAPYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMKTLGADIL
RLWIASADYSNEMSLSQEILKRNADAYRRLRNTARFLLGNLHGFDPLQHLVALDEMVLLDRWIVHRAHELQEKIVAAYAR
YDFAEIVQALLNFCSVDLGSLYLDVTKDRLYTMAEDARGRRSAQSAMYHVAEAFVRWIAPVLSFTAEELWGYLPGKHVDN
VLFATWYDGLAPLPADAALSGADFDKLLVLREQVAKVLEPMRANGAIGAALEAEITVAADAQTAARWQPLAEELRFLFIS
GDVTVTAASTDDIFVSAQPTTKAKCVRCWHHQASVGSDPRHPELCSRCVSNIEGPGERRRWF

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI46852147, Length=984, Percent_Identity=35.1626016260163, Blast_Score=555, Evalue=1e-158,
Organism=Homo sapiens, GI94721239, Length=828, Percent_Identity=29.4685990338164, Blast_Score=317, Evalue=4e-86,
Organism=Homo sapiens, GI94721241, Length=828, Percent_Identity=29.4685990338164, Blast_Score=317, Evalue=4e-86,
Organism=Homo sapiens, GI5454158, Length=823, Percent_Identity=23.8153098420413, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI268370293, Length=882, Percent_Identity=23.6961451247166, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI268370297, Length=882, Percent_Identity=23.6961451247166, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI268370295, Length=854, Percent_Identity=23.6533957845433, Blast_Score=163, Evalue=9e-40,
Organism=Escherichia coli, GI2367096, Length=956, Percent_Identity=55.2301255230126, Blast_Score=1082, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=881, Percent_Identity=22.0204313280363, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71980946, Length=845, Percent_Identity=32.5443786982249, Blast_Score=404, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17541896, Length=947, Percent_Identity=26.7159450897571, Blast_Score=286, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17510661, Length=824, Percent_Identity=24.1504854368932, Blast_Score=190, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI72001587, Length=806, Percent_Identity=23.5732009925558, Blast_Score=165, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325217, Length=997, Percent_Identity=30.1905717151454, Blast_Score=477, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6319395, Length=818, Percent_Identity=28.7286063569682, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6321531, Length=831, Percent_Identity=23.9470517448857, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281366294, Length=962, Percent_Identity=34.0956340956341, Blast_Score=489, Evalue=1e-138,
Organism=Drosophila melanogaster, GI28574730, Length=827, Percent_Identity=27.5695284159613, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24668547, Length=827, Percent_Identity=27.5695284159613, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24668543, Length=827, Percent_Identity=27.5695284159613, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI21355675, Length=876, Percent_Identity=24.6575342465753, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17864482, Length=912, Percent_Identity=22.2587719298246, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24653289, Length=912, Percent_Identity=22.2587719298246, Blast_Score=169, Evalue=1e-41,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_XANAC (Q8PN19)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641590.1
- ProteinModelPortal:   Q8PN19
- GeneID:   1155325
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1254
- NMPDR:   fig|190486.1.peg.1234
- HOGENOM:   HBG577712
- OMA:   KQVLTHG
- ProtClustDB:   PRK05743
- BioCyc:   XAXO190486:XAC1254-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02002
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- InterPro:   IPR010663
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF06827 zf-FPG_IleRS; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 104740; Mature: 104609

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 577-577 BINDING 621-621

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDYKATLHLPATEFPMRGDLPKREPAMLERWEREGFYAQLRANAAGRPLFVLHDGPPY
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCC
ANGQIHLGHAVNKILKDIIVKSKYLAGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVKLDA
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECH
AEFRQKCREYATEQIDLQRRDFKRLGVIGDWDNPYKTLDFRFEANEIRALAKVVDNGHLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC
RGVKPVHWCFDCGSALAEAEIEYADKVSPTVDIAYPARDPAAVAAAFGASLPAGVGVAVP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEE
IWTTTPWTLPASLAVSLGAELDYVLVEGPADRGQPRWLVIAEALAAKALARYGVGEVVVH
EECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEE
GHAKGAALEHMLLNHPFYAEREIPLLLGDHVSAEDGTGAVHTAPGHGQEDYQVSKQYGLL
CCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHCHH
ERYGAAQINPVDGRGVYLPSTPPLRDTVLAGLHIWKANDVIIEALRETGVLLAASKMEHS
HHCCCCCCCCCCCCEEECCCCCCHHHHHHHHEEEECCHHHHHHHHHHCCEEEEEHHHCCC
YPHCWRHKTPIAFRATPQWFISMEQANLRADALKAIENVHWYPSWGQARIAGMVDGRPDW
CCHHHCCCCCEEEECCCHHEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
TISRQRTWGVPIALFVHRETGEPHPRSTELLRQVADRVEQGGVDVWYTLDASELLSSEAA
EEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCC
DYEKITDILDVWFDSGVTHEAVLPDRGLPKPADLYLEGSDQHRGWFQSSLLSGVAMDKAA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMKTLGADILRLWIASADYSNEMSLSQEI
CHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LKRNADAYRRLRNTARFLLGNLHGFDPLQHLVALDEMVLLDRWIVHRAHELQEKIVAAYA
HHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYDFAEIVQALLNFCSVDLGSLYLDVTKDRLYTMAEDARGRRSAQSAMYHVAEAFVRWIA
HCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PVLSFTAEELWGYLPGKHVDNVLFATWYDGLAPLPADAALSGADFDKLLVLREQVAKVLE
HHHHHHHHHHHHCCCCCHHCCCEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PMRANGAIGAALEAEITVAADAQTAARWQPLAEELRFLFISGDVTVTAASTDDIFVSAQP
HHHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCEEEEEECCEEEEEECCCCEEEECCC
TTKAKCVRCWHHQASVGSDPRHPELCSRCVSNIEGPGERRRWF
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQDYKATLHLPATEFPMRGDLPKREPAMLERWEREGFYAQLRANAAGRPLFVLHDGPPY
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCC
ANGQIHLGHAVNKILKDIIVKSKYLAGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVKLDA
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECH
AEFRQKCREYATEQIDLQRRDFKRLGVIGDWDNPYKTLDFRFEANEIRALAKVVDNGHLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC
RGVKPVHWCFDCGSALAEAEIEYADKVSPTVDIAYPARDPAAVAAAFGASLPAGVGVAVP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEE
IWTTTPWTLPASLAVSLGAELDYVLVEGPADRGQPRWLVIAEALAAKALARYGVGEVVVH
EECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEE
GHAKGAALEHMLLNHPFYAEREIPLLLGDHVSAEDGTGAVHTAPGHGQEDYQVSKQYGLL
CCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHCHH
ERYGAAQINPVDGRGVYLPSTPPLRDTVLAGLHIWKANDVIIEALRETGVLLAASKMEHS
HHCCCCCCCCCCCCEEECCCCCCHHHHHHHHEEEECCHHHHHHHHHHCCEEEEEHHHCCC
YPHCWRHKTPIAFRATPQWFISMEQANLRADALKAIENVHWYPSWGQARIAGMVDGRPDW
CCHHHCCCCCEEEECCCHHEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
TISRQRTWGVPIALFVHRETGEPHPRSTELLRQVADRVEQGGVDVWYTLDASELLSSEAA
EEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCC
DYEKITDILDVWFDSGVTHEAVLPDRGLPKPADLYLEGSDQHRGWFQSSLLSGVAMDKAA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMKTLGADILRLWIASADYSNEMSLSQEI
CHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LKRNADAYRRLRNTARFLLGNLHGFDPLQHLVALDEMVLLDRWIVHRAHELQEKIVAAYA
HHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYDFAEIVQALLNFCSVDLGSLYLDVTKDRLYTMAEDARGRRSAQSAMYHVAEAFVRWIA
HCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PVLSFTAEELWGYLPGKHVDNVLFATWYDGLAPLPADAALSGADFDKLLVLREQVAKVLE
HHHHHHHHHHHHCCCCCHHCCCEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PMRANGAIGAALEAEITVAADAQTAARWQPLAEELRFLFISGDVTVTAASTDDIFVSAQP
HHHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCEEEEEECCEEEEEECCCCEEEECCC
TTKAKCVRCWHHQASVGSDPRHPELCSRCVSNIEGPGERRRWF
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217