Click here to switch to the map view.

The map label for this gene is mviN [H]

Identifier: 21242006

GI number: 21242006

Start: 1427886

End: 1429478

Strand: Direct

Name: mviN [H]

Synonym: XAC1252

Alternate gene names: 21242006

Gene position: 1427886-1429478 (Clockwise)

Preceding gene: 21242004

Following gene: 21242007

Centisome position: 27.59

GC content: 64.91

Gene sequence:

>1593_bases
ATGTTGAGAGGCCTGCTCTCATTCAGCAGTATGACCATGATCTCGCGGGTGCTGGGCCTGATCCGCGACCAGGCGATTTC
CACCACCTTCGGCGCCAATGCGGTGACCGACGCGTTCTGGGTGGCCTTTCGCATTCCCAATTTCCTGCGCCGGCTGTTCG
CCGAGGGCTCGTTCGCCACCGCCTTCGTGCCAGTGTTCACCGAGGTCAAGGAGACCCGCCCGCATGCCGATCTGCGCGAG
CTGATGGCGCGCGTGTCCGGCACCTTGGGCGGGATGTTGTTGCTGATCACCGCACTGGGGTTGATCTTCACCCCGCAACT
GGCCGCGGTATTTTCCGATGGCGCGGCCACCGATCCGGAAAAATACGGTTTGTTGGTCGATCTGTTGCGGCTGACCTTTC
CATTCCTGCTGTTCGTCTCGTTGACGGCGCTGGCCGGTGGCGCGCTCAACAGCTTCCAGCGTTTTGCCATTCCGGCGCTG
ACGCCGGTCATCCTCAATTTGTGCATGATTGCCGGCGCGCTGTGGTTGGCGCCGCGGTTGGAGGTCCCGATCCTGGCGCT
GGGCTGGGCGGTCCTGGTGGCCGGTGCGCTGCAGCTGCTGTTCCAGCTGCCGGCGCTGAAGGGCATCGACCTGCTGACGC
TGCCGCGCTGGGGCTGGAATCACCCGGATGTGCGCAAGGTGCTGACCTTGATGATCCCGACCTTGTTCGGCTCGTCGATT
GCGCAGATCAACCTGATGCTGGATACGGTGATCGCCGCGCGCCTGGCCGATGGGTCCCAATCGTGGCTGTCGCTGGCCGA
TCGCTTTCTGGAACTGCCGCTGGGTGTGTTCGGCGTGGCGCTGGGCACGGTGATCCTGCCGGCGCTGGCCCGCCATCATG
TCAAGACCGATCGCACTGCCTTCTCCGGCGCGCTGGACTGGGGCTTCCGCACCACCCTGCTGATCGCGATGCCGGCCATG
CTGGGCTTGCTGCTGCTGGCCGAACCGCTGGTGGCGACGTTGTTCCAGTACCGCCAGTTCACCGCGTTCGATACCCGCAT
GACCGCGATGTCGGTCTACGGCCTGAGCTTCGGTTTGCCGGCCTACGCCATGCTGAAGGTGCTGTTGCCTGCCTTCTACG
CGCGCCAGGACACCCGCACGCCCGTGCGTGCAGGCGTGGCGGCGCTGATTGCCAACATGGTGTTCAACTTCGCGCTGCTG
GCGGTCGTGTACCAGATCATGGTGCCGCCCGAACTCAAGGCGCAGGGTGTGATGCAGGCGCTGGGCAAGCAGCCGGGCCT
GCATCTGGCGTTGGGTATCGCCAGCGCACTGTCGAGTTATCTCAATCTGGGTTTGCTGTGGTACTGGCTGGGCAAGTCCG
GGGTGTACCAGCGCCGGCCGGGCTGGGGCGGCTATGCGCTGCGTCTGCTGCTGGCATGTGCGGCGATGGTGGCAGTGCTG
TTGAGCTTGCTGTGGTGGCTGCCGTCGTTTACGCAGATGGACAAATGGAACCGCATCGGTTGGCTGGCGGTGCTGGTGGG
CAGCGGCGGGGCGACGTATCTGGTTGCGCAATTGGCGCTGGGGCTGCGGCCGCGGCATCTGCGCGAAGGCTGA

Upstream 100 bases:

>100_bases
AAAATCGGTATGGTGGAAAAAGCAAGCGCGAAAGTATGATGGACCCGGATATGTACGTCAAGTCAGTTGTCAAGAGGGAT
GCAGCGTGAGCAAGCCCGGC

Downstream 100 bases:

>100_bases
GGCGACTACCGAACCAGTGCGCTGCAGGTCGCCTGCACTGTCCAGAGATCGCCCATCCCTGCGCAACCGCAGGCGGTGAC
GCGCCGCCCGCCCGGGTACG

Product: virulence factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MLRGLLSFSSMTMISRVLGLIRDQAISTTFGANAVTDAFWVAFRIPNFLRRLFAEGSFATAFVPVFTEVKETRPHADLRE
LMARVSGTLGGMLLLITALGLIFTPQLAAVFSDGAATDPEKYGLLVDLLRLTFPFLLFVSLTALAGGALNSFQRFAIPAL
TPVILNLCMIAGALWLAPRLEVPILALGWAVLVAGALQLLFQLPALKGIDLLTLPRWGWNHPDVRKVLTLMIPTLFGSSI
AQINLMLDTVIAARLADGSQSWLSLADRFLELPLGVFGVALGTVILPALARHHVKTDRTAFSGALDWGFRTTLLIAMPAM
LGLLLLAEPLVATLFQYRQFTAFDTRMTAMSVYGLSFGLPAYAMLKVLLPAFYARQDTRTPVRAGVAALIANMVFNFALL
AVVYQIMVPPELKAQGVMQALGKQPGLHLALGIASALSSYLNLGLLWYWLGKSGVYQRRPGWGGYALRLLLACAAMVAVL
LSLLWWLPSFTQMDKWNRIGWLAVLVGSGGATYLVAQLALGLRPRHLREG

Sequences:

>Translated_530_residues
MLRGLLSFSSMTMISRVLGLIRDQAISTTFGANAVTDAFWVAFRIPNFLRRLFAEGSFATAFVPVFTEVKETRPHADLRE
LMARVSGTLGGMLLLITALGLIFTPQLAAVFSDGAATDPEKYGLLVDLLRLTFPFLLFVSLTALAGGALNSFQRFAIPAL
TPVILNLCMIAGALWLAPRLEVPILALGWAVLVAGALQLLFQLPALKGIDLLTLPRWGWNHPDVRKVLTLMIPTLFGSSI
AQINLMLDTVIAARLADGSQSWLSLADRFLELPLGVFGVALGTVILPALARHHVKTDRTAFSGALDWGFRTTLLIAMPAM
LGLLLLAEPLVATLFQYRQFTAFDTRMTAMSVYGLSFGLPAYAMLKVLLPAFYARQDTRTPVRAGVAALIANMVFNFALL
AVVYQIMVPPELKAQGVMQALGKQPGLHLALGIASALSSYLNLGLLWYWLGKSGVYQRRPGWGGYALRLLLACAAMVAVL
LSLLWWLPSFTQMDKWNRIGWLAVLVGSGGATYLVAQLALGLRPRHLREG
>Mature_530_residues
MLRGLLSFSSMTMISRVLGLIRDQAISTTFGANAVTDAFWVAFRIPNFLRRLFAEGSFATAFVPVFTEVKETRPHADLRE
LMARVSGTLGGMLLLITALGLIFTPQLAAVFSDGAATDPEKYGLLVDLLRLTFPFLLFVSLTALAGGALNSFQRFAIPAL
TPVILNLCMIAGALWLAPRLEVPILALGWAVLVAGALQLLFQLPALKGIDLLTLPRWGWNHPDVRKVLTLMIPTLFGSSI
AQINLMLDTVIAARLADGSQSWLSLADRFLELPLGVFGVALGTVILPALARHHVKTDRTAFSGALDWGFRTTLLIAMPAM
LGLLLLAEPLVATLFQYRQFTAFDTRMTAMSVYGLSFGLPAYAMLKVLLPAFYARQDTRTPVRAGVAALIANMVFNFALL
AVVYQIMVPPELKAQGVMQALGKQPGLHLALGIASALSSYLNLGLLWYWLGKSGVYQRRPGWGGYALRLLLACAAMVAVL
LSLLWWLPSFTQMDKWNRIGWLAVLVGSGGATYLVAQLALGLRPRHLREG

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=526, Percent_Identity=39.7338403041825, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 57666; Mature: 57666

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGLLSFSSMTMISRVLGLIRDQAISTTFGANAVTDAFWVAFRIPNFLRRLFAEGSFAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AFVPVFTEVKETRPHADLRELMARVSGTLGGMLLLITALGLIFTPQLAAVFSDGAATDPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
KYGLLVDLLRLTFPFLLFVSLTALAGGALNSFQRFAIPALTPVILNLCMIAGALWLAPRL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVPILALGWAVLVAGALQLLFQLPALKGIDLLTLPRWGWNHPDVRKVLTLMIPTLFGSSI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCHH
AQINLMLDTVIAARLADGSQSWLSLADRFLELPLGVFGVALGTVILPALARHHVKTDRTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
FSGALDWGFRTTLLIAMPAMLGLLLLAEPLVATLFQYRQFTAFDTRMTAMSVYGLSFGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AYAMLKVLLPAFYARQDTRTPVRAGVAALIANMVFNFALLAVVYQIMVPPELKAQGVMQA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGKQPGLHLALGIASALSSYLNLGLLWYWLGKSGVYQRRPGWGGYALRLLLACAAMVAVL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSLLWWLPSFTQMDKWNRIGWLAVLVGSGGATYLVAQLALGLRPRHLREG
HHHHHHCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MLRGLLSFSSMTMISRVLGLIRDQAISTTFGANAVTDAFWVAFRIPNFLRRLFAEGSFAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AFVPVFTEVKETRPHADLRELMARVSGTLGGMLLLITALGLIFTPQLAAVFSDGAATDPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
KYGLLVDLLRLTFPFLLFVSLTALAGGALNSFQRFAIPALTPVILNLCMIAGALWLAPRL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVPILALGWAVLVAGALQLLFQLPALKGIDLLTLPRWGWNHPDVRKVLTLMIPTLFGSSI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCHH
AQINLMLDTVIAARLADGSQSWLSLADRFLELPLGVFGVALGTVILPALARHHVKTDRTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
FSGALDWGFRTTLLIAMPAMLGLLLLAEPLVATLFQYRQFTAFDTRMTAMSVYGLSFGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AYAMLKVLLPAFYARQDTRTPVRAGVAALIANMVFNFALLAVVYQIMVPPELKAQGVMQA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGKQPGLHLALGIASALSSYLNLGLLWYWLGKSGVYQRRPGWGGYALRLLLACAAMVAVL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSLLWWLPSFTQMDKWNRIGWLAVLVGSGGATYLVAQLALGLRPRHLREG
HHHHHHCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301 [H]