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The map label for this gene is mdcH [H]

Identifier: 21241337

GI number: 21241337

Start: 666996

End: 667916

Strand: Direct

Name: mdcH [H]

Synonym: XAC0566

Alternate gene names: 21241337

Gene position: 666996-667916 (Clockwise)

Preceding gene: 21241336

Following gene: 21241338

Centisome position: 12.89

GC content: 69.82

Gene sequence:

>921_bases
ATGAGCCTGGCCTTGCTCTGCCCGGGCCAAGGCGGCCAACACGCCGAGATGTTCGCGCGTGTCGCAGACGCGCCTGCGGC
GGCCGCCGTCTTCGCCAGCGCACAGCGCGTGCTTGGCGTCGCACCACAAGCACTGGCCGCAGATCCGGGCCGCTACGCCA
ACGCCATCGCTCAACCACTGGTCTGCGCCGGCACGCTGGCGCATTGGCAGGCACTGTGTGCGCAACTCCCCACGCCGCTG
CTGGTGCTCGGTTATAGCGTTGGCGAGCTTGCCGCACATGCGGTGGCCGGCAGCATGTCCATCGACACCTGCCTGCAGCT
GGCGGCGACGCGTGCCCGGTTGATGGATGCGGCCAGCCCGCAGCAGGCAGGGCTGATGGCGGTGATCGGTGTGCCACTGC
GCGCCCTGGAAACGCTGTGCCAGACGCACGGCGCGGCGCTGGCCATCATCAACGGCGACGATCACGCCGTGCTCGGCGGC
CCGCGCGCTGCATTGCAGGCGCTTGGCGAGGCTGCCAGCGCACAAGGTGCGCGCGTCACGCTGCTGCCGGTCGGCGTGCC
GGCGCACACGCCGTGGTTGAGCGCGGCCGCCGAAGGCTTTGCCATTGAACTGGCCACCGCACAGCTCGCCGCGCCCAGGC
TGCGCGTCTTGGCAGGCATCGATGCACGTGCGGTCGGTACGCAGGCCTTGGTGGTCGACACGCTGTCCAGACAGATCGCA
CAGACCGTGCGTTGGTACGACGTGCTGGTACAAGCCGCCGAACGCGGCGCACGCGTGTTCCTCGAACTCGGCCCCGGCAG
CGCATTGGCGCGGATGGCGCGCGAGGTGCTGCCGGCATGCGAAGCGCGCTCGGTGGACGAATTCCACAGCACCGACGGTG
TTCTCGAATGGGTCATGGCTGCGTGCGAGCGCGCGGCATGA

Upstream 100 bases:

>100_bases
TCAATCTCCGCGTCCAGGTTTCCCGGCGGCACATCGCGCGCAATCCGGAACACGACAGGGTGCGCGCACGACATTCCTGC
GAACGCAGTCAGGCCACCGC

Downstream 100 bases:

>100_bases
CGATCAGGCAGGTGCTGCACACGGTGTGACCCCAGGATGGCGGGCGGCCATCCGTGTTGTACGCGTATCAGGTGTCTGGG
AGGGCGCATGACCCCGCAAA

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSLALLCPGQGGQHAEMFARVADAPAAAAVFASAQRVLGVAPQALAADPGRYANAIAQPLVCAGTLAHWQALCAQLPTPL
LVLGYSVGELAAHAVAGSMSIDTCLQLAATRARLMDAASPQQAGLMAVIGVPLRALETLCQTHGAALAIINGDDHAVLGG
PRAALQALGEAASAQGARVTLLPVGVPAHTPWLSAAAEGFAIELATAQLAAPRLRVLAGIDARAVGTQALVVDTLSRQIA
QTVRWYDVLVQAAERGARVFLELGPGSALARMAREVLPACEARSVDEFHSTDGVLEWVMAACERAA

Sequences:

>Translated_306_residues
MSLALLCPGQGGQHAEMFARVADAPAAAAVFASAQRVLGVAPQALAADPGRYANAIAQPLVCAGTLAHWQALCAQLPTPL
LVLGYSVGELAAHAVAGSMSIDTCLQLAATRARLMDAASPQQAGLMAVIGVPLRALETLCQTHGAALAIINGDDHAVLGG
PRAALQALGEAASAQGARVTLLPVGVPAHTPWLSAAAEGFAIELATAQLAAPRLRVLAGIDARAVGTQALVVDTLSRQIA
QTVRWYDVLVQAAERGARVFLELGPGSALARMAREVLPACEARSVDEFHSTDGVLEWVMAACERAA
>Mature_305_residues
SLALLCPGQGGQHAEMFARVADAPAAAAVFASAQRVLGVAPQALAADPGRYANAIAQPLVCAGTLAHWQALCAQLPTPLL
VLGYSVGELAAHAVAGSMSIDTCLQLAATRARLMDAASPQQAGLMAVIGVPLRALETLCQTHGAALAIINGDDHAVLGGP
RAALQALGEAASAQGARVTLLPVGVPAHTPWLSAAAEGFAIELATAQLAAPRLRVLAGIDARAVGTQALVVDTLSRQIAQ
TVRWYDVLVQAAERGARVFLELGPGSALARMAREVLPACEARSVDEFHSTDGVLEWVMAACERAA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=313, Percent_Identity=26.8370607028754, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787334, Length=296, Percent_Identity=28.3783783783784, Blast_Score=95, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=27.8523489932886, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31317; Mature: 31186

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLALLCPGQGGQHAEMFARVADAPAAAAVFASAQRVLGVAPQALAADPGRYANAIAQPL
CCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHH
VCAGTLAHWQALCAQLPTPLLVLGYSVGELAAHAVAGSMSIDTCLQLAATRARLMDAASP
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
QQAGLMAVIGVPLRALETLCQTHGAALAIINGDDHAVLGGPRAALQALGEAASAQGARVT
CCCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHCCCCCEEE
LLPVGVPAHTPWLSAAAEGFAIELATAQLAAPRLRVLAGIDARAVGTQALVVDTLSRQIA
EEEECCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
QTVRWYDVLVQAAERGARVFLELGPGSALARMAREVLPACEARSVDEFHSTDGVLEWVMA
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHH
ACERAA
HHHHCC
>Mature Secondary Structure 
SLALLCPGQGGQHAEMFARVADAPAAAAVFASAQRVLGVAPQALAADPGRYANAIAQPL
CEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHH
VCAGTLAHWQALCAQLPTPLLVLGYSVGELAAHAVAGSMSIDTCLQLAATRARLMDAASP
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
QQAGLMAVIGVPLRALETLCQTHGAALAIINGDDHAVLGGPRAALQALGEAASAQGARVT
CCCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHCCCCCEEE
LLPVGVPAHTPWLSAAAEGFAIELATAQLAAPRLRVLAGIDARAVGTQALVVDTLSRQIA
EEEECCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
QTVRWYDVLVQAAERGARVFLELGPGSALARMAREVLPACEARSVDEFHSTDGVLEWVMA
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHH
ACERAA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]