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The map label for this gene is uppP

Identifier: 21240977

GI number: 21240977

Start: 249859

End: 250656

Strand: Reverse

Name: uppP

Synonym: XAC0203

Alternate gene names: 21240977

Gene position: 250656-249859 (Counterclockwise)

Preceding gene: 21240985

Following gene: 21240976

Centisome position: 4.84

GC content: 64.66

Gene sequence:

>798_bases
ATGTCCGATCTGATTTCCGCCCTGTTGTTGGGCATTCTCGAAGGCCTCACCGAATTTCTGCCGATCTCCAGCACCGGCCA
CCTGCTGATCGCCGAACAATGGCTCGGACGCCGTTCTGACTTCTTCAATATCGTCATCCAGGCCGGCGCGATCCTGGCCA
TCTGCCTGGCGCTGCGGCAGCGCTTGTGGAGCCTGGCCACCGGCCTGGGCGAACGCGCCAACCGCGACTACGTGCTCAAG
GTAGGCGTGGCCTTCCTGGTCACAGCGGTGGTCGGGCTGATCGTGCGCAAGGCCGGCTGGCAATTGCCCGAAACGCTGCA
ACCGGTCGCCTGGGCGTTGCTGATCGGCGGGGTGTGGATGCTGGTGGCCGAACACTTCGCCGGCAAGCTGCCCGAGCGCG
ATGTGGTGACCTGGAAGGTGGCCATCGCAGTGGGCCTGGCGCAGGTCGTGGCCGGTGTTTTTCCCGGTACGTCACGCTCG
GCCTCGACGATCTTCATCGCGATGCTGCTGGGCCTGAGCAAGCGCTCGGCAGCGGCGGATTTCGTGTTCATGGTGGGCAT
TCCGACCATGTTCGCGGCCAGCGGTTACGCGCTGCTGGAGATGTACAAGGAAGGCGGTTTCGGCACCGAAAACTGGGCCG
ACGTGGCCGTGGCCTTCGTGGCGGCGACCATCACCGGCTTTGTGGTGGTGAAGTGGCTGCTGGGCTATATCAAGAAGCAC
CGTTTCACGGTGTTTGCGGTGTACCGCATGCTGCTGGGCGCCGCCCTGCTGCTGTGGCTGCCGGCGGCTGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGTATTGCACTATTGAGGTGCAAAAATGGACACGCCGCACCGATGTGGTGCATGCCGCAATGCACTATCCTGGCGCCTC
CCTCACCCCTGCCCAGTCCG

Downstream 100 bases:

>100_bases
CACGCCACGGCACCGCCTGCCTGCACTCCGAGACGGGTGCGATGTGCAGCCAGGGGCGGCCAGCAACGTAAAGCGCCGTC
CCCAAGAAGTTGTGGGTGGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLK
VGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASTIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWADVAVAFVAATITGFVVVKWLLGYIKKH
RFTVFAVYRMLLGAALLLWLPAAAG

Sequences:

>Translated_265_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLK
VGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASTIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWADVAVAFVAATITGFVVVKWLLGYIKKH
RFTVFAVYRMLLGAALLLWLPAAAG
>Mature_264_residues
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQRLWSLATGLGERANRDYVLKV
GVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSA
STIFIAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGTENWADVAVAFVAATITGFVVVKWLLGYIKKHR
FTVFAVYRMLLGAALLLWLPAAAG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=271, Percent_Identity=35.0553505535055, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_XANAC (Q8PQW6)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640559.1
- GeneID:   1154274
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0203
- NMPDR:   fig|190486.1.peg.203
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   XAXO190486:XAC0203-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28494; Mature: 28363

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xc3161dc)-; HASH(0xc93cf60)-; HASH(0xc12a5b0)-; HASH(0xc9512bc)-; HASH(0xc939d98)-; HASH(0xc94e6f8)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RLWSLATGLGERANRDYVLKVGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASTIFIAMLLGLSKRSAAAD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHH
FVFMVGIPTMFAASGYALLEMYKEGGFGTENWADVAVAFVAATITGFVVVKWLLGYIKKH
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTVFAVYRMLLGAALLLWLPAAAG
HHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RLWSLATGLGERANRDYVLKVGVAFLVTAVVGLIVRKAGWQLPETLQPVAWALLIGGVWM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASTIFIAMLLGLSKRSAAAD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHH
FVFMVGIPTMFAASGYALLEMYKEGGFGTENWADVAVAFVAATITGFVVVKWLLGYIKKH
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTVFAVYRMLLGAALLLWLPAAAG
HHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217