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The map label for this gene is ubiE [C]

Identifier: 21226832

GI number: 21226832

Start: 880280

End: 881011

Strand: Reverse

Name: ubiE [C]

Synonym: MM_0730

Alternate gene names: 21226832

Gene position: 881011-880280 (Counterclockwise)

Preceding gene: 21226837

Following gene: 21226831

Centisome position: 21.51

GC content: 46.45

Gene sequence:

>732_bases
GTGGTGCATACTCCTCTGAATTTCAAATTCTCTGAAAAAAGAGAAGAATGGAACCTGCGGTTTTGCAGGAATGTCGGAGT
CTCCATTGTGGAACTGGTTACAGCCGATGCCAGCAGTGCTTACGTGAGGGGTTTGATGGCTGTTAACGGGTCAAAAGTCT
ATTCTATCCTTCCTTTCATCTCAATAGATGCAGAAAAAGCAAAAAAAGCTAAATTCCCTGAAGACCGCATGTCCGGTGTA
AGGGGCAAGGTGATCCCATCCGTGCTTCCGGAAATAAAAGGGGAAACTATCCTTGATATTGGCTGCGGTTTCGGGACACT
CACAATGGAGCTTGCAAAAAATAACCCTGAATCGCAGGTTTACGGCATTGACCTTCATGATTCCCTCACAGGCCAGGCAG
AAATGAATGCTGAAGTCCTCGGATTGCCAAATGTTGAGTTCAGGACAGGAAGCGCCTATGCCCTGCCTTTTGAAAAGGAC
TCGATAGACGCTGTAACCTGCTTTTTAATGCTCCATCACCTGGAGGATATTAAGTTCGCACTTTTTGAGATCAAAAGAGT
GTTGAAAAAAGGCGGGTCATTAACTGCAGTTGAGCCGCTGGCACACCAGCACCATCACGGGCCCCAGCTTTCGGAAGCCG
AATGGAAAGAGCTTTTTGAGGAAGCAGGTTTTGGTACGGAAACCGAAAATATGGAAGGAGCAGTTGTTTTGAGAGCCGTG
AAAAGAGAATAA

Upstream 100 bases:

>100_bases
GCAAATCCTCTCCCTTTTCAGGGAAAGCATAAGCGAAATTCGCCTGAATGAACCTGAATCAGTATCAGCATACTTCAGCC
CCAGCTATTCGTATTATATC

Downstream 100 bases:

>100_bases
TATTAATATTGAGATGAGTGATTTTAAAAATGGATTGAAAGATTTTCAGAACATGATTATGAATTTTATTTTCTTTCAAT
CCATCTTATCAGCTGTTCAT

Product: SAM-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MVHTPLNFKFSEKREEWNLRFCRNVGVSIVELVTADASSAYVRGLMAVNGSKVYSILPFISIDAEKAKKAKFPEDRMSGV
RGKVIPSVLPEIKGETILDIGCGFGTLTMELAKNNPESQVYGIDLHDSLTGQAEMNAEVLGLPNVEFRTGSAYALPFEKD
SIDAVTCFLMLHHLEDIKFALFEIKRVLKKGGSLTAVEPLAHQHHHGPQLSEAEWKELFEEAGFGTETENMEGAVVLRAV
KRE

Sequences:

>Translated_243_residues
MVHTPLNFKFSEKREEWNLRFCRNVGVSIVELVTADASSAYVRGLMAVNGSKVYSILPFISIDAEKAKKAKFPEDRMSGV
RGKVIPSVLPEIKGETILDIGCGFGTLTMELAKNNPESQVYGIDLHDSLTGQAEMNAEVLGLPNVEFRTGSAYALPFEKD
SIDAVTCFLMLHHLEDIKFALFEIKRVLKKGGSLTAVEPLAHQHHHGPQLSEAEWKELFEEAGFGTETENMEGAVVLRAV
KRE
>Mature_243_residues
MVHTPLNFKFSEKREEWNLRFCRNVGVSIVELVTADASSAYVRGLMAVNGSKVYSILPFISIDAEKAKKAKFPEDRMSGV
RGKVIPSVLPEIKGETILDIGCGFGTLTMELAKNNPESQVYGIDLHDSLTGQAEMNAEVLGLPNVEFRTGSAYALPFEKD
SIDAVTCFLMLHHLEDIKFALFEIKRVLKKGGSLTAVEPLAHQHHHGPQLSEAEWKELFEEAGFGTETENMEGAVVLRAV
KRE

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26906; Mature: 26906

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHTPLNFKFSEKREEWNLRFCRNVGVSIVELVTADASSAYVRGLMAVNGSKVYSILPFI
CCCCCCCCCCCCCHHHHCHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCCCCCEEEEECEE
SIDAEKAKKAKFPEDRMSGVRGKVIPSVLPEIKGETILDIGCGFGTLTMELAKNNPESQV
ECCHHHHHHCCCCHHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCEE
YGIDLHDSLTGQAEMNAEVLGLPNVEFRTGSAYALPFEKDSIDAVTCFLMLHHLEDIKFA
EEEECCCCCCCCCCCCEEEEECCCCEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LFEIKRVLKKGGSLTAVEPLAHQHHHGPQLSEAEWKELFEEAGFGTETENMEGAVVLRAV
HHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
KRE
CCC
>Mature Secondary Structure
MVHTPLNFKFSEKREEWNLRFCRNVGVSIVELVTADASSAYVRGLMAVNGSKVYSILPFI
CCCCCCCCCCCCCHHHHCHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCCCCCEEEEECEE
SIDAEKAKKAKFPEDRMSGVRGKVIPSVLPEIKGETILDIGCGFGTLTMELAKNNPESQV
ECCHHHHHHCCCCHHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCEE
YGIDLHDSLTGQAEMNAEVLGLPNVEFRTGSAYALPFEKDSIDAVTCFLMLHHLEDIKFA
EEEECCCCCCCCCCCCEEEEECCCCEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LFEIKRVLKKGGSLTAVEPLAHQHHHGPQLSEAEWKELFEEAGFGTETENMEGAVVLRAV
HHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
KRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]