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The map label for this gene is ftsZ [H]

Identifier: 21226799

GI number: 21226799

Start: 836856

End: 838034

Strand: Direct

Name: ftsZ [H]

Synonym: MM_0697

Alternate gene names: 21226799

Gene position: 836856-838034 (Clockwise)

Preceding gene: 21226797

Following gene: 21226800

Centisome position: 20.43

GC content: 49.02

Gene sequence:

>1179_bases
TTGCAATCTATAGTACAGGAAGCAATGAAGTTCAGCGAAAAAGAAAAGGAATACCGAAAAACGACGTCCGATGAAGAATT
CGAAGAATTCGGACAGCCGAGAATTATGATTGTAGGGTGTGGGGGCGCAGGGAATAATACCGTAAACCGTCTCTACAACA
TTGGAATTGAAGGCGCAGAAACAGTCTGCATCAATACGGATAAGCAGCACCTTGACAATGTAAGGGCTGACAAGAAGATC
CTTGTTGGAAAAACCCTTACAAGAGGACTGGGAGCAGGCGGCTATCCAGAAACAGGGAAAAAAGCCGCAGAACTTGCAAG
AGGCACCCTTGAAGAAGTCCTGAAGGATGTTGACCTTGTTTTCGTTACCGCAGGCCTCGGAGGAGGCACTGGAACAGGAG
TTGCCCCGGTAGTTGCCGAAGTTGCAAAAGAACAGGGAGCAATCGTTGTGGGCATGGTTTCAAGCCCCTTCAGAGTCGAA
AGAGCCCGCATATTTAAAGCCGAAGAGGGTCTCGAAGACCTGCGCAGGGCAGCAGACACGGTAATTGTCCTGGACAACAA
CAGGCTGCTCAATTATGTACCCAACCTTCCCATTGACCAGGCTTTCTCAGTAATGGACCAGTTAATTGCAGAAACCGTAA
AGGGAATAACCGAAACCATTACTGTGCCTTCTCTGATCAACCTTGACTATGCAGATATAAGGACAATCATGAGCTGCGGC
GGAGTTGCCGTAATGCTTGTAGGAGAGTCAAAGAACCAGGACAAGAGCACCGAAGTCGTGAGGACTGCCCTTAACCACCC
GCTGCTTGATGTTGATTATAAGGGCGCAACCGGTAGCCTTGTCCATGTAACAGGCGGGCCTGACCTCAGCCTGAAGGAAG
CCGAAGAAATTGCCTCCATGCTTACCTATGAACTTTCCTCGAACGCCAATGTGATATGGGGCGCAAGGATAAGGGATGAT
TATGAAGGTAAGGTCCGGGTAATGGCAATAATGACCGGTGTCCAGTCTGCCCAGATCCTGGGCCCTCAGGCAGGAGCTGG
AATCCTGGAGTCCAGAGCCGAAGCTGACCCTATCCAGGAAAAAAGATTTGGAAGGCTGTCACTTGAAGCCAGGAAAGCCG
GGACTGCAGGTCCTCTGAGAAAAAAGCACGAAGAATCAATTATTGATTTCATAAATTAA

Upstream 100 bases:

>100_bases
TTAATTGATATCAGCAAAATTTACCCCCCGACAAAGAGGGTGGGGAGTGAAAGAAAAAATAGAGAAGATATAATAAACGA
AATCCGACCGAGGGGATAAA

Downstream 100 bases:

>100_bases
TTACGTTAAGGCAAAAGCCCGAATCTGCAGGTTTTCGGGCTCCCTCAGTTATTTTTTCAGGATATTCGGGGAGCTACCGG
AGACCTGGAGAAACAAATCT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MQSIVQEAMKFSEKEKEYRKTTSDEEFEEFGQPRIMIVGCGGAGNNTVNRLYNIGIEGAETVCINTDKQHLDNVRADKKI
LVGKTLTRGLGAGGYPETGKKAAELARGTLEEVLKDVDLVFVTAGLGGGTGTGVAPVVAEVAKEQGAIVVGMVSSPFRVE
RARIFKAEEGLEDLRRAADTVIVLDNNRLLNYVPNLPIDQAFSVMDQLIAETVKGITETITVPSLINLDYADIRTIMSCG
GVAVMLVGESKNQDKSTEVVRTALNHPLLDVDYKGATGSLVHVTGGPDLSLKEAEEIASMLTYELSSNANVIWGARIRDD
YEGKVRVMAIMTGVQSAQILGPQAGAGILESRAEADPIQEKRFGRLSLEARKAGTAGPLRKKHEESIIDFIN

Sequences:

>Translated_392_residues
MQSIVQEAMKFSEKEKEYRKTTSDEEFEEFGQPRIMIVGCGGAGNNTVNRLYNIGIEGAETVCINTDKQHLDNVRADKKI
LVGKTLTRGLGAGGYPETGKKAAELARGTLEEVLKDVDLVFVTAGLGGGTGTGVAPVVAEVAKEQGAIVVGMVSSPFRVE
RARIFKAEEGLEDLRRAADTVIVLDNNRLLNYVPNLPIDQAFSVMDQLIAETVKGITETITVPSLINLDYADIRTIMSCG
GVAVMLVGESKNQDKSTEVVRTALNHPLLDVDYKGATGSLVHVTGGPDLSLKEAEEIASMLTYELSSNANVIWGARIRDD
YEGKVRVMAIMTGVQSAQILGPQAGAGILESRAEADPIQEKRFGRLSLEARKAGTAGPLRKKHEESIIDFIN
>Mature_392_residues
MQSIVQEAMKFSEKEKEYRKTTSDEEFEEFGQPRIMIVGCGGAGNNTVNRLYNIGIEGAETVCINTDKQHLDNVRADKKI
LVGKTLTRGLGAGGYPETGKKAAELARGTLEEVLKDVDLVFVTAGLGGGTGTGVAPVVAEVAKEQGAIVVGMVSSPFRVE
RARIFKAEEGLEDLRRAADTVIVLDNNRLLNYVPNLPIDQAFSVMDQLIAETVKGITETITVPSLINLDYADIRTIMSCG
GVAVMLVGESKNQDKSTEVVRTALNHPLLDVDYKGATGSLVHVTGGPDLSLKEAEEIASMLTYELSSNANVIWGARIRDD
YEGKVRVMAIMTGVQSAQILGPQAGAGILESRAEADPIQEKRFGRLSLEARKAGTAGPLRKKHEESIIDFIN

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Assemble at the Inner Surface of the Cytoplasmic Membrane. [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=39.7260273972603, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 42235; Mature: 42235

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01134 FTSZ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIVQEAMKFSEKEKEYRKTTSDEEFEEFGQPRIMIVGCGGAGNNTVNRLYNIGIEGAE
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
TVCINTDKQHLDNVRADKKILVGKTLTRGLGAGGYPETGKKAAELARGTLEEVLKDVDLV
EEEEECCHHHHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
FVTAGLGGGTGTGVAPVVAEVAKEQGAIVVGMVSSPFRVERARIFKAEEGLEDLRRAADT
EEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCE
VIVLDNNRLLNYVPNLPIDQAFSVMDQLIAETVKGITETITVPSLINLDYADIRTIMSCG
EEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCC
GVAVMLVGESKNQDKSTEVVRTALNHPLLDVDYKGATGSLVHVTGGPDLSLKEAEEIASM
CEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHH
LTYELSSNANVIWGARIRDDYEGKVRVMAIMTGVQSAQILGPQAGAGILESRAEADPIQE
HHHHHCCCCCEEEECEECCCCCCCEEEEEEECCCCHHHHCCCCCCCHHHHHCCCCCCHHH
KRFGRLSLEARKAGTAGPLRKKHEESIIDFIN
HHCCCEEEHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSIVQEAMKFSEKEKEYRKTTSDEEFEEFGQPRIMIVGCGGAGNNTVNRLYNIGIEGAE
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
TVCINTDKQHLDNVRADKKILVGKTLTRGLGAGGYPETGKKAAELARGTLEEVLKDVDLV
EEEEECCHHHHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
FVTAGLGGGTGTGVAPVVAEVAKEQGAIVVGMVSSPFRVERARIFKAEEGLEDLRRAADT
EEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCE
VIVLDNNRLLNYVPNLPIDQAFSVMDQLIAETVKGITETITVPSLINLDYADIRTIMSCG
EEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCC
GVAVMLVGESKNQDKSTEVVRTALNHPLLDVDYKGATGSLVHVTGGPDLSLKEAEEIASM
CEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHH
LTYELSSNANVIWGARIRDDYEGKVRVMAIMTGVQSAQILGPQAGAGILESRAEADPIQE
HHHHHCCCCCEEEECEECCCCCCCEEEEEEECCCCHHHHCCCCCCCHHHHHCCCCCCHHH
KRFGRLSLEARKAGTAGPLRKKHEESIIDFIN
HHCCCEEEHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8631708; 11016950 [H]