Click here to switch to the map view.

The map label for this gene is kynB [H]

Identifier: 21226708

GI number: 21226708

Start: 737371

End: 738099

Strand: Reverse

Name: kynB [H]

Synonym: MM_0606

Alternate gene names: 21226708

Gene position: 738099-737371 (Counterclockwise)

Preceding gene: 21226709

Following gene: 21226706

Centisome position: 18.02

GC content: 43.21

Gene sequence:

>729_bases
ATGTTTCCTCCGGAAAAAATGCCTTTCAAGGGAAAAATTACAGATATTACAGTTCCAATTTCTCCTTCCACTCCTATCTT
TCCCGGAGACCCGGAACCTTCAATCGAAAGTGCCTTTACTATAGAAAAAGACGGGTGTGCAGTATCCAGGCTGATTTTAG
GAAGCCATACAGGCACGCACGTCGATGCTCCTTCTCACATCCTGAAAGATGGACTCGCTGTTGACGATTTAAATCTTGAA
AATCTTATAGGTCAGGCGGTTGTTCTGGATTTCTCCTTCAGAAATGGGGCATTGACAGACTATATTCTTGACAAAGCTTA
CAATCACCTGAAGAACACTGACCATGTCTCAATTCTACTTCTAAAGACAAAACCTTCTTTCCATTATGAAAATAACTCAA
GGGTTTCAGGTCTTCAGGCGGGCGAAAGCAATAAAGGAATAGAATTTGAGGAGCCGCCTGAAAATTCTGTTTATCTTGAT
TCCGGCGCTGCGGAATGGATTGTCCGGAATGGGTTCAAAACAGTTGGAATTGACAGCTTTTCCGTTGACAATCTCTCTTC
GGAAAATCTGTCTGCCCATCATATATTGCTTTCAAACAACGTGAATATAGTGGAATGCCTTGACATGAGTTCGGTGGAAG
CAGGAATTTATTTTTTCCTGTGCCTGCCTCTGAAAATTGAGGGCTGCGACGGTGCTCCGGCAAGAGCATTGCTGATACCT
TACTCCTGA

Upstream 100 bases:

>100_bases
GCAAAGCAAGATGGGAACTGAAGAAAATTAGAATGAATTTAGAGAAAAAACTAAAATGAAACCTAAAAGAGTCAGAAAAT
TCAGGAAAAGGTGAAATGAG

Downstream 100 bases:

>100_bases
TTTTCCCCGGTTTTTTCTGAATTTCCCTTTCCCCTCTGGCTTTCGCCTGTTTTTTTCCTGACTTTCAGAAGCGCGCCATT
GTATACCTTGTACCGTTGTG

Product: hypothetical protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MFPPEKMPFKGKITDITVPISPSTPIFPGDPEPSIESAFTIEKDGCAVSRLILGSHTGTHVDAPSHILKDGLAVDDLNLE
NLIGQAVVLDFSFRNGALTDYILDKAYNHLKNTDHVSILLLKTKPSFHYENNSRVSGLQAGESNKGIEFEEPPENSVYLD
SGAAEWIVRNGFKTVGIDSFSVDNLSSENLSAHHILLSNNVNIVECLDMSSVEAGIYFFLCLPLKIEGCDGAPARALLIP
YS

Sequences:

>Translated_242_residues
MFPPEKMPFKGKITDITVPISPSTPIFPGDPEPSIESAFTIEKDGCAVSRLILGSHTGTHVDAPSHILKDGLAVDDLNLE
NLIGQAVVLDFSFRNGALTDYILDKAYNHLKNTDHVSILLLKTKPSFHYENNSRVSGLQAGESNKGIEFEEPPENSVYLD
SGAAEWIVRNGFKTVGIDSFSVDNLSSENLSAHHILLSNNVNIVECLDMSSVEAGIYFFLCLPLKIEGCDGAPARALLIP
YS
>Mature_242_residues
MFPPEKMPFKGKITDITVPISPSTPIFPGDPEPSIESAFTIEKDGCAVSRLILGSHTGTHVDAPSHILKDGLAVDDLNLE
NLIGQAVVLDFSFRNGALTDYILDKAYNHLKNTDHVSILLLKTKPSFHYENNSRVSGLQAGESNKGIEFEEPPENSVYLD
SGAAEWIVRNGFKTVGIDSFSVDNLSSENLSAHHILLSNNVNIVECLDMSSVEAGIYFFLCLPLKIEGCDGAPARALLIP
YS

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 26317; Mature: 26317

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPPEKMPFKGKITDITVPISPSTPIFPGDPEPSIESAFTIEKDGCAVSRLILGSHTGTH
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCC
VDAPSHILKDGLAVDDLNLENLIGQAVVLDFSFRNGALTDYILDKAYNHLKNTDHVSILL
CCCCHHHHHCCCEEECCCHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
LKTKPSFHYENNSRVSGLQAGESNKGIEFEEPPENSVYLDSGAAEWIVRNGFKTVGIDSF
EECCCCEEECCCCEECEEECCCCCCCCCCCCCCCCCEEEECCCCEEHHHCCCEEECCCCC
SVDNLSSENLSAHHILLSNNVNIVECLDMSSVEAGIYFFLCLPLKIEGCDGAPARALLIP
CCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCCCEEEEEE
YS
CC
>Mature Secondary Structure
MFPPEKMPFKGKITDITVPISPSTPIFPGDPEPSIESAFTIEKDGCAVSRLILGSHTGTH
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCC
VDAPSHILKDGLAVDDLNLENLIGQAVVLDFSFRNGALTDYILDKAYNHLKNTDHVSILL
CCCCHHHHHCCCEEECCCHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
LKTKPSFHYENNSRVSGLQAGESNKGIEFEEPPENSVYLDSGAAEWIVRNGFKTVGIDSF
EECCCCEEECCCCEECEEECCCCCCCCCCCCCCCCCEEEECCCCEEHHHCCCEEECCCCC
SVDNLSSENLSAHHILLSNNVNIVECLDMSSVEAGIYFFLCLPLKIEGCDGAPARALLIP
CCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCCCEEEEEE
YS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA