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The map label for this gene is ynfJ [C]

Identifier: 21226600

GI number: 21226600

Start: 619683

End: 621452

Strand: Direct

Name: ynfJ [C]

Synonym: MM_0498

Alternate gene names: 21226600

Gene position: 619683-621452 (Clockwise)

Preceding gene: 21226599

Following gene: 21226601

Centisome position: 15.13

GC content: 50.23

Gene sequence:

>1770_bases
TTGGAAGTTAAGCCAGAGTCCAGATTCGGTATCCACAGAATAAAAGAATACCCCAGGCTAATCGAGTACATCAGCAGATT
TGATACAGAAGCTACCAGGGTCAATTCAATTGCCATTTTAATAGGACTCCTGACAGGGCTCGTTATAGGAGTTTATGACC
GCGCTCTCCAGTACAGCAATACTCTTTTTGGGATGCAGCAGGGGTTCTCTTTACACGAATTCCCGCATTACTACGTAATC
TTCATGCCCGCCCTCGGAGGGCTGGTGGTGGGGGCGATCTCTCACTTCCTGATAAAAAAGAGGTACGGTGTAGAAGGTCT
TATAGAAACCGTAACCCTCAGAGGAGCAAGAATAAAGCTCACTGATGTTTTTCTGGAAGTATTCACTTCAATAATTACTA
TCAGCTCCGGAGGCGCTCTCGGAAAGGAGGCTCCGGGGGTCCTTGCAGGAGCAGGGACAGGCTCTTTTGTCGGGAAAATC
CTGAAAAGCCCGGAAAGACAGCTCCAGGTCCTTCTCGGGTGCGGGGCTGCCGGAGGGATTGCAGCTGCTTTCAGCGCTCC
GCTTGCAGGCGTGGTCTTCGTGGTGGAAGTGATTTACGGGGAACTTGAAACAAAAACCTTTATTCCGATAGTAATTTCAT
CCGTCTTTGCAACCCTTGTCTCAAGCACTCTTTTCGGGATAAAACCCATAGAGATCTCTTCCTACCAGCTGGTCAGCCCC
TATAAAGAGGTCGGGCTCTGCCTTATCCTCGGGCTCCTTGCAGGAGTGATCTCAACTATCCTTATCCAGGCTCTCTATTA
TATGAAAGACCTTTTTTCGGAAATCCCTGTCCACCCCGTCTTCAAGCCTGCCCTTGGCGGTCTTGCGGTGGGCGCACTCG
GCCTATTTTATCCCAGAGTTCTCGGGATGGGATATAACGTTATCATGGATGCCCTGAACAACCAGCTTGCCTTTAACCTC
CTGTTAATCCTTCTCTTCCTGAAAATACTCGCATTCTCCCTGAGCCTGGGCTCGGGAGGTTCAGGAGGAACAATTGTGCC
CTCTCTTTTCACAGGCGCAATGCTTGGAGGAGCCTTCGGGACAGCTGCAAACCTCCTCTTTCCGGGGACAATAGCAGAGC
CGGGAGCCTATGCCATGATAGGGATGGGGGCTGTCTTTGCCGGAACTGCGAGGGCGCCACTTACCGCTATCCTGATCCTT
TTTGAGATGACCAGAGACTACAGCCTTATTCTTCCACTTATGTTTTCCTGCGTCCTGAGCAACGTGATGTCAAATGCCCT
GTACCCGGAGTCGATTTTCACGGAAGGGCTCCGCAGGAAAGGGTTCAAGATCCGGAAAGGCAGGGAAGTAGATATTATGG
ACTCCATGCTTGTGAAAGATGCAATGGTCACACATGTCCAGACCGTCTCGGAAGAAAAAAATGTGGGGACCCTTATCGCC
CTCATGCAGGCGAGCCGTCATGCCGGTTTTCCGGTGCTGGATTCAAAAGGCAAACTTTCAGGGATAGTAACACTTTCAGA
CCTCCGCAGCAAAGTAAAGTATGGAGAAGTTGACAAGAAAATAGGGGACATCGCTACCCGCACCGTAGAAGTAGCCTATC
CCGACGAAACCCTTGAAGCCGTTCTCAGACGCCTTGGATCAAAGCAGATAGGCAGGCTTCCTGTCGTGGACCACGAGGAA
AAGACAAAACTCCTGGGTCTCATTACCCGGAGCGACGTCGTAAACTCATACAACAAGAAAGTGATAGAAAAAGTTAGGGA
TACGGAATAA

Upstream 100 bases:

>100_bases
ATTCAGGCAGATTAATATTAAGAGTTATTCAGAGCCCTGAGGATTTACTTTTTTCAAAAAAAGAGTTGAAGCGTAAAAAA
CTCCTGAGAGGCGCGAACAT

Downstream 100 bases:

>100_bases
TTGCTTCACCCGTAAAATACAGGCATTTGAAAGTGGTGAACAAAAAGTCCCTCACACAAGAGATATTCTAATCATACTCG
ATTCATTAAAAAATTGATTT

Product: putative chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MEVKPESRFGIHRIKEYPRLIEYISRFDTEATRVNSIAILIGLLTGLVIGVYDRALQYSNTLFGMQQGFSLHEFPHYYVI
FMPALGGLVVGAISHFLIKKRYGVEGLIETVTLRGARIKLTDVFLEVFTSIITISSGGALGKEAPGVLAGAGTGSFVGKI
LKSPERQLQVLLGCGAAGGIAAAFSAPLAGVVFVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIEISSYQLVSP
YKEVGLCLILGLLAGVISTILIQALYYMKDLFSEIPVHPVFKPALGGLAVGALGLFYPRVLGMGYNVIMDALNNQLAFNL
LLILLFLKILAFSLSLGSGGSGGTIVPSLFTGAMLGGAFGTAANLLFPGTIAEPGAYAMIGMGAVFAGTARAPLTAILIL
FEMTRDYSLILPLMFSCVLSNVMSNALYPESIFTEGLRRKGFKIRKGREVDIMDSMLVKDAMVTHVQTVSEEKNVGTLIA
LMQASRHAGFPVLDSKGKLSGIVTLSDLRSKVKYGEVDKKIGDIATRTVEVAYPDETLEAVLRRLGSKQIGRLPVVDHEE
KTKLLGLITRSDVVNSYNKKVIEKVRDTE

Sequences:

>Translated_589_residues
MEVKPESRFGIHRIKEYPRLIEYISRFDTEATRVNSIAILIGLLTGLVIGVYDRALQYSNTLFGMQQGFSLHEFPHYYVI
FMPALGGLVVGAISHFLIKKRYGVEGLIETVTLRGARIKLTDVFLEVFTSIITISSGGALGKEAPGVLAGAGTGSFVGKI
LKSPERQLQVLLGCGAAGGIAAAFSAPLAGVVFVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIEISSYQLVSP
YKEVGLCLILGLLAGVISTILIQALYYMKDLFSEIPVHPVFKPALGGLAVGALGLFYPRVLGMGYNVIMDALNNQLAFNL
LLILLFLKILAFSLSLGSGGSGGTIVPSLFTGAMLGGAFGTAANLLFPGTIAEPGAYAMIGMGAVFAGTARAPLTAILIL
FEMTRDYSLILPLMFSCVLSNVMSNALYPESIFTEGLRRKGFKIRKGREVDIMDSMLVKDAMVTHVQTVSEEKNVGTLIA
LMQASRHAGFPVLDSKGKLSGIVTLSDLRSKVKYGEVDKKIGDIATRTVEVAYPDETLEAVLRRLGSKQIGRLPVVDHEE
KTKLLGLITRSDVVNSYNKKVIEKVRDTE
>Mature_589_residues
MEVKPESRFGIHRIKEYPRLIEYISRFDTEATRVNSIAILIGLLTGLVIGVYDRALQYSNTLFGMQQGFSLHEFPHYYVI
FMPALGGLVVGAISHFLIKKRYGVEGLIETVTLRGARIKLTDVFLEVFTSIITISSGGALGKEAPGVLAGAGTGSFVGKI
LKSPERQLQVLLGCGAAGGIAAAFSAPLAGVVFVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIEISSYQLVSP
YKEVGLCLILGLLAGVISTILIQALYYMKDLFSEIPVHPVFKPALGGLAVGALGLFYPRVLGMGYNVIMDALNNQLAFNL
LLILLFLKILAFSLSLGSGGSGGTIVPSLFTGAMLGGAFGTAANLLFPGTIAEPGAYAMIGMGAVFAGTARAPLTAILIL
FEMTRDYSLILPLMFSCVLSNVMSNALYPESIFTEGLRRKGFKIRKGREVDIMDSMLVKDAMVTHVQTVSEEKNVGTLIA
LMQASRHAGFPVLDSKGKLSGIVTLSDLRSKVKYGEVDKKIGDIATRTVEVAYPDETLEAVLRRLGSKQIGRLPVVDHEE
KTKLLGLITRSDVVNSYNKKVIEKVRDTE

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI189217923, Length=565, Percent_Identity=24.4247787610619, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI189217921, Length=565, Percent_Identity=24.4247787610619, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4557473, Length=566, Percent_Identity=24.3816254416961, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI153252026, Length=561, Percent_Identity=23.5294117647059, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI167466160, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI119433677, Length=443, Percent_Identity=23.2505643340858, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI14149607, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081943, Length=308, Percent_Identity=32.4675324675325, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786350, Length=402, Percent_Identity=31.0945273631841, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17532615, Length=551, Percent_Identity=23.5934664246824, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24665008, Length=538, Percent_Identity=24.7211895910781, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 63408; Mature: 63408

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKPESRFGIHRIKEYPRLIEYISRFDTEATRVNSIAILIGLLTGLVIGVYDRALQYSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFGMQQGFSLHEFPHYYVIFMPALGGLVVGAISHFLIKKRYGVEGLIETVTLRGARIKL
HHHHHHCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEHH
TDVFLEVFTSIITISSGGALGKEAPGVLAGAGTGSFVGKILKSPERQLQVLLGCGAAGGI
HHHHHHHHHHHHEECCCCCCCCCCCCCEEECCCHHHHHHHHHCHHHHHHHHHHCCCCCHH
AAAFSAPLAGVVFVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIEISSYQLVSP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHCC
YKEVGLCLILGLLAGVISTILIQALYYMKDLFSEIPVHPVFKPALGGLAVGALGLFYPRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LGMGYNVIMDALNNQLAFNLLLILLFLKILAFSLSLGSGGSGGTIVPSLFTGAMLGGAFG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
TAANLLFPGTIAEPGAYAMIGMGAVFAGTARAPLTAILILFEMTRDYSLILPLMFSCVLS
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NVMSNALYPESIFTEGLRRKGFKIRKGREVDIMDSMLVKDAMVTHVQTVSEEKNVGTLIA
HHHHCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LMQASRHAGFPVLDSKGKLSGIVTLSDLRSKVKYGEVDKKIGDIATRTVEVAYPDETLEA
HHHHHHCCCCCEECCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHEEEEECCCHHHHH
VLRRLGSKQIGRLPVVDHEEKTKLLGLITRSDVVNSYNKKVIEKVRDTE
HHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEVKPESRFGIHRIKEYPRLIEYISRFDTEATRVNSIAILIGLLTGLVIGVYDRALQYSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFGMQQGFSLHEFPHYYVIFMPALGGLVVGAISHFLIKKRYGVEGLIETVTLRGARIKL
HHHHHHCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEHH
TDVFLEVFTSIITISSGGALGKEAPGVLAGAGTGSFVGKILKSPERQLQVLLGCGAAGGI
HHHHHHHHHHHHEECCCCCCCCCCCCCEEECCCHHHHHHHHHCHHHHHHHHHHCCCCCHH
AAAFSAPLAGVVFVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIEISSYQLVSP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHCC
YKEVGLCLILGLLAGVISTILIQALYYMKDLFSEIPVHPVFKPALGGLAVGALGLFYPRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LGMGYNVIMDALNNQLAFNLLLILLFLKILAFSLSLGSGGSGGTIVPSLFTGAMLGGAFG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
TAANLLFPGTIAEPGAYAMIGMGAVFAGTARAPLTAILILFEMTRDYSLILPLMFSCVLS
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NVMSNALYPESIFTEGLRRKGFKIRKGREVDIMDSMLVKDAMVTHVQTVSEEKNVGTLIA
HHHHCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LMQASRHAGFPVLDSKGKLSGIVTLSDLRSKVKYGEVDKKIGDIATRTVEVAYPDETLEA
HHHHHHCCCCCEECCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHEEEEECCCHHHHH
VLRRLGSKQIGRLPVVDHEEKTKLLGLITRSDVVNSYNKKVIEKVRDTE
HHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]