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The map label for this gene is yeeO [C]

Identifier: 21226450

GI number: 21226450

Start: 454925

End: 456394

Strand: Reverse

Name: yeeO [C]

Synonym: MM_0348

Alternate gene names: 21226450

Gene position: 456394-454925 (Counterclockwise)

Preceding gene: 21226455

Following gene: 21226449

Centisome position: 11.14

GC content: 47.41

Gene sequence:

>1470_bases
ATGAGCAGGGAAGCAGTAGAACAAAAGGGGCAGGGAGAGGAAGACTCAAAGGAAAACAGGGATCAAGAAAGAAAAACGGA
AACGAAATCCCCTCATAAAGTTACAGAAGGCGTGGATATCCTCCTTGGGGACCCCGAAAAAGCTGTAATCAAGCTCTCCA
TTCCTATTATAGTTGCAATGGGTGTACAGACCATTTACAGCCTCACCGATACCTTCTGGGTCGCAGGCCTTGGTGCGGAT
GCCCTGGCTGCCGTAGGTTTTGCATTCCCTTTTTTTGTAATCCAGATGGCTCTTACAGGCGGGCTTGGAGTCGGTGGCGG
TGCTGCAATTTCCCGCAGGATAGGGGCCAGGGATAAAGCCGGAGCGGACAATGTTGCAGTACATACATTTGTAATTATGC
TGGTACTGACCGTTGTTCTCACAGGGATAGGGCTTTCTCTTGTGAGAGACTTATTCGTATTCAGCGGGGCAGGAGAAACT
ACTCCACTCGGAGTTGCGTACGCAAGGGTACTTTTTGCAGGCAGTTTTGTGTTCTTCTTTACAAATGTCGCAAACTCCAT
ACTCAGGAGTGAAGGAGATTCAAAAAGAGCTATGCAGTCGATGGTCCTTGGATCTCTCCTGAACGTCGTCCTTGACCCGA
TTTTTATATATGTGCTGGACCTGGGAGTTGCAGGAGCAGCCCTTGCTACAGTATTCTCCTTCTCCTGTTCCGGACTGCTT
ATGTTTTACTGGTTTTTTATCAAAAAAAATACCTATATATCATTCGCTTTCCGTTCCTTCAAATTCAACCGGGATATTGC
AAAAGACATTTTCAGGGTAGCCATACCTTCTTCAATAGAACAGGTTGCTCTCGCCCTTACTGCCCTGATAATGAATTATA
TTATAGTGAATGTCAGCAATACTGACGGGGTTGCTGTTTACGCTACAGCCTGGAGGATTACAAGCATTGCGGTTTCCCCT
CTAATAGGAATTTCAATCTCCGTGGTCTCGATTTCGGGAGCAGCTTTCGGGGAAAGGAGTTATAAAAAAGCAAGAAGCGC
TCTTCTTTATGCAACAAGGACAGGTTTTCTGGTAGAAGCAGCAGTCGCAGTTGCAGTATATATCTTCGCTCCGTATATTG
CTGGCGCCTTTACGCAGGCAGAAAATACTGCCCAGATAGCCCCTGAACTGACAAGGCTGCTTAAAATCATGACCGTATTT
TATCCGGCTGTTGCTTTCGGAATGCTCTCTGCCTCTCTTTTTCAGGGTGCGGGAAAGGGTACAAGCGCACTTATTGCCAC
ACTCCTTAGAAGTTTGATACTGACGCCGGTATTTGCCCTGCTTTTTGCCTTTACATTCGGCTGGGGGTTGTCCGGAGTCT
GGTGGGGGCTTGTTATGGGAACAGTTGTTGGGTCGCTGGTCACCTTTGCGTGGGCGCAGGTTTATTTGAGGCGCATGATA
AAGGTAGAAGGAGAGGGAGAGAAGTGTTGA

Upstream 100 bases:

>100_bases
ATTACATATGAGAAAATGTTAAAGGCTGAGAGACTAAAGAAGAATAGGGCAAAAACTTTTGTTAGAATGAAAATATGATA
GTCCAAAAACGGTGTGGAAA

Downstream 100 bases:

>100_bases
AAACTCAGAGTCCTCCCATTACTCCACGTGCAGTCTATCCGCTCAACCCCATATAATCCTGCTCAGCATCATACAACTTT
TTTACTTTCTTATTTGTGCC

Product: putative cation efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSREAVEQKGQGEEDSKENRDQERKTETKSPHKVTEGVDILLGDPEKAVIKLSIPIIVAMGVQTIYSLTDTFWVAGLGAD
ALAAVGFAFPFFVIQMALTGGLGVGGGAAISRRIGARDKAGADNVAVHTFVIMLVLTVVLTGIGLSLVRDLFVFSGAGET
TPLGVAYARVLFAGSFVFFFTNVANSILRSEGDSKRAMQSMVLGSLLNVVLDPIFIYVLDLGVAGAALATVFSFSCSGLL
MFYWFFIKKNTYISFAFRSFKFNRDIAKDIFRVAIPSSIEQVALALTALIMNYIIVNVSNTDGVAVYATAWRITSIAVSP
LIGISISVVSISGAAFGERSYKKARSALLYATRTGFLVEAAVAVAVYIFAPYIAGAFTQAENTAQIAPELTRLLKIMTVF
YPAVAFGMLSASLFQGAGKGTSALIATLLRSLILTPVFALLFAFTFGWGLSGVWWGLVMGTVVGSLVTFAWAQVYLRRMI
KVEGEGEKC

Sequences:

>Translated_489_residues
MSREAVEQKGQGEEDSKENRDQERKTETKSPHKVTEGVDILLGDPEKAVIKLSIPIIVAMGVQTIYSLTDTFWVAGLGAD
ALAAVGFAFPFFVIQMALTGGLGVGGGAAISRRIGARDKAGADNVAVHTFVIMLVLTVVLTGIGLSLVRDLFVFSGAGET
TPLGVAYARVLFAGSFVFFFTNVANSILRSEGDSKRAMQSMVLGSLLNVVLDPIFIYVLDLGVAGAALATVFSFSCSGLL
MFYWFFIKKNTYISFAFRSFKFNRDIAKDIFRVAIPSSIEQVALALTALIMNYIIVNVSNTDGVAVYATAWRITSIAVSP
LIGISISVVSISGAAFGERSYKKARSALLYATRTGFLVEAAVAVAVYIFAPYIAGAFTQAENTAQIAPELTRLLKIMTVF
YPAVAFGMLSASLFQGAGKGTSALIATLLRSLILTPVFALLFAFTFGWGLSGVWWGLVMGTVVGSLVTFAWAQVYLRRMI
KVEGEGEKC
>Mature_488_residues
SREAVEQKGQGEEDSKENRDQERKTETKSPHKVTEGVDILLGDPEKAVIKLSIPIIVAMGVQTIYSLTDTFWVAGLGADA
LAAVGFAFPFFVIQMALTGGLGVGGGAAISRRIGARDKAGADNVAVHTFVIMLVLTVVLTGIGLSLVRDLFVFSGAGETT
PLGVAYARVLFAGSFVFFFTNVANSILRSEGDSKRAMQSMVLGSLLNVVLDPIFIYVLDLGVAGAALATVFSFSCSGLLM
FYWFFIKKNTYISFAFRSFKFNRDIAKDIFRVAIPSSIEQVALALTALIMNYIIVNVSNTDGVAVYATAWRITSIAVSPL
IGISISVVSISGAAFGERSYKKARSALLYATRTGFLVEAAVAVAVYIFAPYIAGAFTQAENTAQIAPELTRLLKIMTVFY
PAVAFGMLSASLFQGAGKGTSALIATLLRSLILTPVFALLFAFTFGWGLSGVWWGLVMGTVVGSLVTFAWAQVYLRRMIK
VEGEGEKC

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=455, Percent_Identity=23.956043956044, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52368; Mature: 52237

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCCC
>Mature Secondary Structure 
SREAVEQKGQGEEDSKENRDQERKTETKSPHKVTEGVDILLGDPEKAVIKLSIPIIVAM
CCHHHHHCCCCCCCHHHCCHHHHHHCCCCCCHHHCCCEEEECCCCCEEEEEEHHHHHHH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HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]