Definition Methanosarcina mazei Go1 chromosome, complete genome.
Accession NC_003901
Length 4,096,345

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The map label for this gene is cheA [H]

Identifier: 21226430

GI number: 21226430

Start: 432728

End: 435373

Strand: Reverse

Name: cheA [H]

Synonym: MM_0328

Alternate gene names: 21226430

Gene position: 435373-432728 (Counterclockwise)

Preceding gene: 161485682

Following gene: 21226429

Centisome position: 10.63

GC content: 43.12

Gene sequence:

>2646_bases
ATGGAAAGTGATATGGCAGCCTATAAAAGCGATTTCCTTCAGGAAGTATACGAGTGCCTTGATATATTCAACCAGTCTTT
TGTGGACCTGGAAAATGGGGACACTGCTGCAATTGATGAAATCTTCAGGATAACCCATACAATAAAAGGAATGGCTGGAT
TTCTCGGCTATGCTTCACTCGAACATCTGTGCCATACCATGGAAGAAGTCCTCTGCGGCATAAAAAATGGAGATATAGAG
ATAGATGGCGAACTTGTTGATATCCTGCTTTCAACAGTCGACCGGATCACGGATATTGTCAAACAGATCGAGAATGCGGA
TAACGATAATGTAAAAATTGACGACCTGGTAGAAGCTTTTGAAAATTATGATAAAATAAAGAACGGAGAACATGAATCTC
TCTGCCCTTTATCCGCAGACAACAGTGTCCCATCTCCTGCAATAGAATCCTCACAGAATTCGGAGAAAAATATTTCTCCG
AGTCCGGAATATCAGAAGGATAAAGCCGAAAACAGAGGGACATGCAGTACGGATGGCTGCAACCTTATGAACAGAGGAAC
ATGCAGTACGGATGAGTGCAACCTTGTTCTTGATGTAACCCTTGTTAAGGATTGTGCCATGAAAGGTCTGAGAGCATCGT
TGATTATAGAGTCTCTCAAAGATATCAGTAAACTGGCTAAAACAGAGCCTGATGAAAACGACATGGAGAACGGCTTTGAC
GGTTGCTTTAAAGTATTCCTTTCAGGGGACAGCAGTAAGGTAGAAGAACTGATGGATAGAATTTCAGAAATCGAACAATT
TAATATTTCTGAAATTAAACCGCTTAATGGTGCCTCTGATAAAGAAATAAAACGTAATAATTCTATTTCGGAGAAGTCTC
AGCCGGATGTCATATCAACTACCATTCTGCCGTCTGAAACCCTTTCCGTTCCTTCTGATACAACGTCTGTTTCGGAGGTG
AACAGCAGAAATTCACTCCACTCATACATATACGGTTTAATAGCAAGGATGCACCGCATTCTGGACGGAATTGGTAAATC
CGTAAACTGTTTTAAAAAGACCGAATCCGCCGGAGTGCTCCTGAAGAAAAAATGTAAGGATTCCAGGGGAGATATTCCGG
AGCAGCAGGAAACTCTAGAGCAACAGGAAACTCTAGAGCAGCAGAAAACTCCAGCTTCCGAACTGGATATTGAACTGGGT
CCTGCAGTTTCCGATCAAAAGCTGCAGATAGAAGAATTCGGGATTCCTGATCATGTTCCAGAAAAGGTTTCTGAGGAGGA
TCTTCCGGACTGGAACATCTCGGACAGGATCATTGATGGTCTGGAGATAAAGCCGGATAAATTCCAATCTCCTGCAGAAA
ATATTAACGGCTCTTCTCCTCAGTTACTGGAGTTATGCGAAGCTTCCGGGACTGAAGAATCCGAACCGGGTTCAAACAAC
CACCTCTCCGAATCAGAATCCTCCACAAAAGCGATGTTTGACCCAAAAAGGCAGGAAACCATCCGTGTCAGGACCTCCAA
TCTGGATAATATAATGAATCTTGTGGGTGAGCTCGTCATAAACAAAGGGCGCCTGCTCCAGATATCCCAGCAGTACAACC
TGCCTGAACTTGGGGAGGCAACCGGGACTCTGGACAAATCGATTTCGAGCCTTCAGGATGAGGTAATGAGAATAAGGATG
GTAAAAATTGAGAGGGTCTTCAGCAAGTTTCCGCGTATGGTAAGAGACCTGAGCAGGAAATTCAACAAAAATATCGAGTT
TGAAATTGAAGGTCAGGATACGGAACTTGACAGGACTATTCTGGATGATATCAGTGATCCTCTGGTTCACCTTGTAAGAA
ACTCGGTTGACCACGGTATTGAACTCCCTGAAGAGCGTTCAAAAGCCGGAAAAAGTGAAGTCGGGCAAATAAAGCTCTCT
GCAAGAAGAGAGAAAAACAACGTAATCATCGAGATAGAAGACGACGGCAGAGGCATAGATGTTGAAGTAATAAAGAAGAA
GGCTGTTGAGAAAGGACTATTGTCTTCATTTGATGTGGAGAGCCTGAGCGAAGAAGAAGTCAGGATGCTGATCTTTGCTC
CGGGGTTTTCAACAAAGGACGTCCCGACAGAGATCTCAGGCAGGGGCGTGGGTATGGACGCAGTAAAAACTGCTGTTGAA
AAACTTGGTGGAAAGGTCAGGATATATTCAAAGAAAGGGGAATTTACAAAAATCAGAATTGACCTGCCTCCAACAGTTGC
TATAATCAAATCCCTGCTTGTAGATGTCGGTCCCGAGACCTATGCTATTCCTATCTCCAATGTTGTGAAAGCTTTGAGCG
TCGGCAGCAGTGATTATAAACTCATTAAAGAAACCCCCCTGCTCTATATCAGGGATAAATTGATACCGATTCTCGAATTG
AAAGAATTCTTCGATATCGAATGCGAAAAACCCGACCGGCAGATTGCCATAATCGTTGAAAAAGAAAACGAGGAAGTTGG
CCTGATAGTTGATTCTATCATTGACCAGCAGGAAATTGTCATTAAACCACTCGGAAATGTTTTATCGAACTCAAAAGGAT
TCATCGGTGCCACCATACTGGGAGATGGGCGTGTGATACCGATTATAGATGTTTCAATGCTTATAAAAGGTGATATTGAT
GACTGA

Upstream 100 bases:

>100_bases
GGAATGCCAAAAGCTGCAATAGCAGCCGGCGGTATTGATACGGTAAAACCCATTTTTGAGATCCCTGAAGAAATAGTAAG
GATGTCGGAGGTGAAATGCA

Downstream 100 bases:

>100_bases
TCTGGATAAGCTTGGTGAAGAGGAAATGGATGTTTTGAAGGAACTCGGCAATATCGGAACCGGACACGCTGCAACATCTC
TTTCCAAGCTGCTTAATAAA

Product: chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 881; Mature: 881

Protein sequence:

>881_residues
MESDMAAYKSDFLQEVYECLDIFNQSFVDLENGDTAAIDEIFRITHTIKGMAGFLGYASLEHLCHTMEEVLCGIKNGDIE
IDGELVDILLSTVDRITDIVKQIENADNDNVKIDDLVEAFENYDKIKNGEHESLCPLSADNSVPSPAIESSQNSEKNISP
SPEYQKDKAENRGTCSTDGCNLMNRGTCSTDECNLVLDVTLVKDCAMKGLRASLIIESLKDISKLAKTEPDENDMENGFD
GCFKVFLSGDSSKVEELMDRISEIEQFNISEIKPLNGASDKEIKRNNSISEKSQPDVISTTILPSETLSVPSDTTSVSEV
NSRNSLHSYIYGLIARMHRILDGIGKSVNCFKKTESAGVLLKKKCKDSRGDIPEQQETLEQQETLEQQKTPASELDIELG
PAVSDQKLQIEEFGIPDHVPEKVSEEDLPDWNISDRIIDGLEIKPDKFQSPAENINGSSPQLLELCEASGTEESEPGSNN
HLSESESSTKAMFDPKRQETIRVRTSNLDNIMNLVGELVINKGRLLQISQQYNLPELGEATGTLDKSISSLQDEVMRIRM
VKIERVFSKFPRMVRDLSRKFNKNIEFEIEGQDTELDRTILDDISDPLVHLVRNSVDHGIELPEERSKAGKSEVGQIKLS
ARREKNNVIIEIEDDGRGIDVEVIKKKAVEKGLLSSFDVESLSEEEVRMLIFAPGFSTKDVPTEISGRGVGMDAVKTAVE
KLGGKVRIYSKKGEFTKIRIDLPPTVAIIKSLLVDVGPETYAIPISNVVKALSVGSSDYKLIKETPLLYIRDKLIPILEL
KEFFDIECEKPDRQIAIIVEKENEEVGLIVDSIIDQQEIVIKPLGNVLSNSKGFIGATILGDGRVIPIIDVSMLIKGDID
D

Sequences:

>Translated_881_residues
MESDMAAYKSDFLQEVYECLDIFNQSFVDLENGDTAAIDEIFRITHTIKGMAGFLGYASLEHLCHTMEEVLCGIKNGDIE
IDGELVDILLSTVDRITDIVKQIENADNDNVKIDDLVEAFENYDKIKNGEHESLCPLSADNSVPSPAIESSQNSEKNISP
SPEYQKDKAENRGTCSTDGCNLMNRGTCSTDECNLVLDVTLVKDCAMKGLRASLIIESLKDISKLAKTEPDENDMENGFD
GCFKVFLSGDSSKVEELMDRISEIEQFNISEIKPLNGASDKEIKRNNSISEKSQPDVISTTILPSETLSVPSDTTSVSEV
NSRNSLHSYIYGLIARMHRILDGIGKSVNCFKKTESAGVLLKKKCKDSRGDIPEQQETLEQQETLEQQKTPASELDIELG
PAVSDQKLQIEEFGIPDHVPEKVSEEDLPDWNISDRIIDGLEIKPDKFQSPAENINGSSPQLLELCEASGTEESEPGSNN
HLSESESSTKAMFDPKRQETIRVRTSNLDNIMNLVGELVINKGRLLQISQQYNLPELGEATGTLDKSISSLQDEVMRIRM
VKIERVFSKFPRMVRDLSRKFNKNIEFEIEGQDTELDRTILDDISDPLVHLVRNSVDHGIELPEERSKAGKSEVGQIKLS
ARREKNNVIIEIEDDGRGIDVEVIKKKAVEKGLLSSFDVESLSEEEVRMLIFAPGFSTKDVPTEISGRGVGMDAVKTAVE
KLGGKVRIYSKKGEFTKIRIDLPPTVAIIKSLLVDVGPETYAIPISNVVKALSVGSSDYKLIKETPLLYIRDKLIPILEL
KEFFDIECEKPDRQIAIIVEKENEEVGLIVDSIIDQQEIVIKPLGNVLSNSKGFIGATILGDGRVIPIIDVSMLIKGDID
D
>Mature_881_residues
MESDMAAYKSDFLQEVYECLDIFNQSFVDLENGDTAAIDEIFRITHTIKGMAGFLGYASLEHLCHTMEEVLCGIKNGDIE
IDGELVDILLSTVDRITDIVKQIENADNDNVKIDDLVEAFENYDKIKNGEHESLCPLSADNSVPSPAIESSQNSEKNISP
SPEYQKDKAENRGTCSTDGCNLMNRGTCSTDECNLVLDVTLVKDCAMKGLRASLIIESLKDISKLAKTEPDENDMENGFD
GCFKVFLSGDSSKVEELMDRISEIEQFNISEIKPLNGASDKEIKRNNSISEKSQPDVISTTILPSETLSVPSDTTSVSEV
NSRNSLHSYIYGLIARMHRILDGIGKSVNCFKKTESAGVLLKKKCKDSRGDIPEQQETLEQQETLEQQKTPASELDIELG
PAVSDQKLQIEEFGIPDHVPEKVSEEDLPDWNISDRIIDGLEIKPDKFQSPAENINGSSPQLLELCEASGTEESEPGSNN
HLSESESSTKAMFDPKRQETIRVRTSNLDNIMNLVGELVINKGRLLQISQQYNLPELGEATGTLDKSISSLQDEVMRIRM
VKIERVFSKFPRMVRDLSRKFNKNIEFEIEGQDTELDRTILDDISDPLVHLVRNSVDHGIELPEERSKAGKSEVGQIKLS
ARREKNNVIIEIEDDGRGIDVEVIKKKAVEKGLLSSFDVESLSEEEVRMLIFAPGFSTKDVPTEISGRGVGMDAVKTAVE
KLGGKVRIYSKKGEFTKIRIDLPPTVAIIKSLLVDVGPETYAIPISNVVKALSVGSSDYKLIKETPLLYIRDKLIPILEL
KEFFDIECEKPDRQIAIIVEKENEEVGLIVDSIIDQQEIVIKPLGNVLSNSKGFIGATILGDGRVIPIIDVSMLIKGDID
D

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=381, Percent_Identity=43.8320209973753, Blast_Score=301, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97770; Mature: 97770

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESDMAAYKSDFLQEVYECLDIFNQSFVDLENGDTAAIDEIFRITHTIKGMAGFLGYASL
CCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLCHTMEEVLCGIKNGDIEIDGELVDILLSTVDRITDIVKQIENADNDNVKIDDLVEAF
HHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHH
ENYDKIKNGEHESLCPLSADNSVPSPAIESSQNSEKNISPSPEYQKDKAENRGTCSTDGC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
NLMNRGTCSTDECNLVLDVTLVKDCAMKGLRASLIIESLKDISKLAKTEPDENDMENGFD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GCFKVFLSGDSSKVEELMDRISEIEQFNISEIKPLNGASDKEIKRNNSISEKSQPDVIST
HHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEE
TILPSETLSVPSDTTSVSEVNSRNSLHSYIYGLIARMHRILDGIGKSVNCFKKTESAGVL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHH
LKKKCKDSRGDIPEQQETLEQQETLEQQKTPASELDIELGPAVSDQKLQIEEFGIPDHVP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCEEHHHCCCCCCCC
EKVSEEDLPDWNISDRIIDGLEIKPDKFQSPAENINGSSPQLLELCEASGTEESEPGSNN
HHCCCCCCCCCCCHHHHHCCCCCCCHHCCCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
HLSESESSTKAMFDPKRQETIRVRTSNLDNIMNLVGELVINKGRLLQISQQYNLPELGEA
CCCCCCCCCHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
TGTLDKSISSLQDEVMRIRMVKIERVFSKFPRMVRDLSRKFNKNIEFEIEGQDTELDRTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
LDDISDPLVHLVRNSVDHGIELPEERSKAGKSEVGQIKLSARREKNNVIIEIEDDGRGID
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCEEEEEEECCCCCEEEEECCCCCCCH
VEVIKKKAVEKGLLSSFDVESLSEEEVRMLIFAPGFSTKDVPTEISGRGVGMDAVKTAVE
HHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
KLGGKVRIYSKKGEFTKIRIDLPPTVAIIKSLLVDVGPETYAIPISNVVKALSVGSSDYK
HCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCH
LIKETPLLYIRDKLIPILELKEFFDIECEKPDRQIAIIVEKENEEVGLIVDSIIDQQEIV
HHHCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCHHHH
IKPLGNVLSNSKGFIGATILGDGRVIPIIDVSMLIKGDIDD
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHEECCCCC
>Mature Secondary Structure
MESDMAAYKSDFLQEVYECLDIFNQSFVDLENGDTAAIDEIFRITHTIKGMAGFLGYASL
CCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLCHTMEEVLCGIKNGDIEIDGELVDILLSTVDRITDIVKQIENADNDNVKIDDLVEAF
HHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHH
ENYDKIKNGEHESLCPLSADNSVPSPAIESSQNSEKNISPSPEYQKDKAENRGTCSTDGC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
NLMNRGTCSTDECNLVLDVTLVKDCAMKGLRASLIIESLKDISKLAKTEPDENDMENGFD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GCFKVFLSGDSSKVEELMDRISEIEQFNISEIKPLNGASDKEIKRNNSISEKSQPDVIST
HHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEE
TILPSETLSVPSDTTSVSEVNSRNSLHSYIYGLIARMHRILDGIGKSVNCFKKTESAGVL
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHH
LKKKCKDSRGDIPEQQETLEQQETLEQQKTPASELDIELGPAVSDQKLQIEEFGIPDHVP
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCEEHHHCCCCCCCC
EKVSEEDLPDWNISDRIIDGLEIKPDKFQSPAENINGSSPQLLELCEASGTEESEPGSNN
HHCCCCCCCCCCCHHHHHCCCCCCCHHCCCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
HLSESESSTKAMFDPKRQETIRVRTSNLDNIMNLVGELVINKGRLLQISQQYNLPELGEA
CCCCCCCCCHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
TGTLDKSISSLQDEVMRIRMVKIERVFSKFPRMVRDLSRKFNKNIEFEIEGQDTELDRTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
LDDISDPLVHLVRNSVDHGIELPEERSKAGKSEVGQIKLSARREKNNVIIEIEDDGRGID
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCEEEEEEECCCCCEEEEECCCCCCCH
VEVIKKKAVEKGLLSSFDVESLSEEEVRMLIFAPGFSTKDVPTEISGRGVGMDAVKTAVE
HHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
KLGGKVRIYSKKGEFTKIRIDLPPTVAIIKSLLVDVGPETYAIPISNVVKALSVGSSDYK
HCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCH
LIKETPLLYIRDKLIPILELKEFFDIECEKPDRQIAIIVEKENEEVGLIVDSIIDQQEIV
HHHCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCHHHH
IKPLGNVLSNSKGFIGATILGDGRVIPIIDVSMLIKGDIDD
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]