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The map label for this gene is pqqE [H]

Identifier: 21226411

GI number: 21226411

Start: 412310

End: 413509

Strand: Direct

Name: pqqE [H]

Synonym: MM_0309

Alternate gene names: 21226411

Gene position: 412310-413509 (Clockwise)

Preceding gene: 21226410

Following gene: 21226413

Centisome position: 10.07

GC content: 48.83

Gene sequence:

>1200_bases
ATGATAGGAATTTCAAAACTTTACTGCGGAACCGTGGAACCTTCTGACGCCCTTCGTTATGGAAGGGACTCAAAGAAGCT
CCCCTCTCACCTTCTGCAGTTTTCAAAAGATAAAAAGCCGGTTGTGGTCTGGAACATGACCCGCCGCTGCAACCTGAAGT
GTGTCCACTGTTACGCTCAGGCAAAGGATGAAGAGTTCAAAAACGAGCTCTCAACAGAAGAAGGAAAAGCCCTTATCGAT
GACCTTGCAGCTTTTGGGTCCCCGGTTATGCTCTTTTCGGGTGGCGAGCCCACTATTCGAAAGGACCTGCCCGAACTTGC
AGCCTATGCCCGCGAAAAAGGTATGAGAGCTGTAATCTCAACAAATGGCACCCTCATTGATAAGGACCTGGCAAAAAAGC
TAAAGGAAGTCGGGCTTTCTTATGTGGGGATCTCGCTTGACGGCATAAGGGAGACTAACGATAAATTCAGGGGCATGTCT
GGAGCTTTTGATGCGGCTCTCAGGGGCCTGTACAACTGCCAGGAAGAAGGCATAAAGGTAGGTCTTCGCTTTACAATCAA
CAAACAAAATGTAAAGGATATTCCTGCGATCTTTGACCTTCTTGAGAAAGAAAATATCCCCAGGATCTGCTTTTACCACC
TTGTCTATGCCGGCAGGGGCTCGAAAATGGTGGATGAAGACCTCTCTCTTGAAGATTCCAGAAAGGCTGTTGACCTGATC
ATGCAAAGGACCAGGGAACTGCACGAAAAAGGCTTCCCTGCAGAAGTACTTACCGTGGACAACCACTGCGACGGCCCCTA
CATTTACCTGAAAATGCTGAAAGAAAACCCTGAAAGGGCTGCCGAAATTTTTGAGCTCCTTTCAATGAACCAGGGAAATT
CCTCAGGAATAGGGATAGGATGCGTTTCCTGGGACGGTTCGGTCCACGCCGACCAGTTCTGGAGGCACTACTCCTTCGGA
AATGTGCGGGAAAGACCTTTCAGCGAGATCTGGACCGACCTCAGTGACGAACTTATGGCAGGGCTCAAGTACAGGAAGCC
CCTCATCCAGGCTAACGGAGACCGATGTGCAAAATGCAAATGGTTTGATGTATGCAACGGAAACTTCAGGGTAAGAGCCG
AAGCAGTATACGGAAACGTATGGGCGGATGACCCGGCTTGCTATCTTACAAAAGAAGAAATAGGATACGATGAAGCCTGA

Upstream 100 bases:

>100_bases
CCAGAGCCGGTTAAAAATATTTCCAGTTAAAAAACAATATTTATTATAGTTCTGTGGAACAATCTGGTTCTGGAAAACAA
TCTCACTTTTAAGGATCAAT

Downstream 100 bases:

>100_bases
AAACAATTCAGGCTTTATTAAATTTCAATGTTTCTTTTAAATTTCAATGTTCCTTAATTCCTGTTATTTTTTGAACTATA
CCATTCTGGTATGAATGTTT

Product: metallo cofactor biosynthesis protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIGISKLYCGTVEPSDALRYGRDSKKLPSHLLQFSKDKKPVVVWNMTRRCNLKCVHCYAQAKDEEFKNELSTEEGKALID
DLAAFGSPVMLFSGGEPTIRKDLPELAAYAREKGMRAVISTNGTLIDKDLAKKLKEVGLSYVGISLDGIRETNDKFRGMS
GAFDAALRGLYNCQEEGIKVGLRFTINKQNVKDIPAIFDLLEKENIPRICFYHLVYAGRGSKMVDEDLSLEDSRKAVDLI
MQRTRELHEKGFPAEVLTVDNHCDGPYIYLKMLKENPERAAEIFELLSMNQGNSSGIGIGCVSWDGSVHADQFWRHYSFG
NVRERPFSEIWTDLSDELMAGLKYRKPLIQANGDRCAKCKWFDVCNGNFRVRAEAVYGNVWADDPACYLTKEEIGYDEA

Sequences:

>Translated_399_residues
MIGISKLYCGTVEPSDALRYGRDSKKLPSHLLQFSKDKKPVVVWNMTRRCNLKCVHCYAQAKDEEFKNELSTEEGKALID
DLAAFGSPVMLFSGGEPTIRKDLPELAAYAREKGMRAVISTNGTLIDKDLAKKLKEVGLSYVGISLDGIRETNDKFRGMS
GAFDAALRGLYNCQEEGIKVGLRFTINKQNVKDIPAIFDLLEKENIPRICFYHLVYAGRGSKMVDEDLSLEDSRKAVDLI
MQRTRELHEKGFPAEVLTVDNHCDGPYIYLKMLKENPERAAEIFELLSMNQGNSSGIGIGCVSWDGSVHADQFWRHYSFG
NVRERPFSEIWTDLSDELMAGLKYRKPLIQANGDRCAKCKWFDVCNGNFRVRAEAVYGNVWADDPACYLTKEEIGYDEA
>Mature_399_residues
MIGISKLYCGTVEPSDALRYGRDSKKLPSHLLQFSKDKKPVVVWNMTRRCNLKCVHCYAQAKDEEFKNELSTEEGKALID
DLAAFGSPVMLFSGGEPTIRKDLPELAAYAREKGMRAVISTNGTLIDKDLAKKLKEVGLSYVGISLDGIRETNDKFRGMS
GAFDAALRGLYNCQEEGIKVGLRFTINKQNVKDIPAIFDLLEKENIPRICFYHLVYAGRGSKMVDEDLSLEDSRKAVDLI
MQRTRELHEKGFPAEVLTVDNHCDGPYIYLKMLKENPERAAEIFELLSMNQGNSSGIGIGCVSWDGSVHADQFWRHYSFG
NVRERPFSEIWTDLSDELMAGLKYRKPLIQANGDRCAKCKWFDVCNGNFRVRAEAVYGNVWADDPACYLTKEEIGYDEA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

Organism=Escherichia coli, GI87081923, Length=340, Percent_Identity=25.2941176470588, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 45008; Mature: 45008

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGISKLYCGTVEPSDALRYGRDSKKLPSHLLQFSKDKKPVVVWNMTRRCNLKCVHCYAQ
CCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEHH
AKDEEFKNELSTEEGKALIDDLAAFGSPVMLFSGGEPTIRKDLPELAAYAREKGMRAVIS
CCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
TNGTLIDKDLAKKLKEVGLSYVGISLDGIRETNDKFRGMSGAFDAALRGLYNCQEEGIKV
CCCCEECHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCEEE
GLRFTINKQNVKDIPAIFDLLEKENIPRICFYHLVYAGRGSKMVDEDLSLEDSRKAVDLI
EEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
MQRTRELHEKGFPAEVLTVDNHCDGPYIYLKMLKENPERAAEIFELLSMNQGNSSGIGIG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHCCHHHHHHHHHHHHCCCCCCCCEEEE
CVSWDGSVHADQFWRHYSFGNVRERPFSEIWTDLSDELMAGLKYRKPLIQANGDRCAKCK
EEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCHHCCCCCCCCCEE
WFDVCNGNFRVRAEAVYGNVWADDPACYLTKEEIGYDEA
EEEEECCCEEEEEEEEECCEECCCCCEEEEHHHCCCCCC
>Mature Secondary Structure
MIGISKLYCGTVEPSDALRYGRDSKKLPSHLLQFSKDKKPVVVWNMTRRCNLKCVHCYAQ
CCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEHH
AKDEEFKNELSTEEGKALIDDLAAFGSPVMLFSGGEPTIRKDLPELAAYAREKGMRAVIS
CCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
TNGTLIDKDLAKKLKEVGLSYVGISLDGIRETNDKFRGMSGAFDAALRGLYNCQEEGIKV
CCCCEECHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCEEE
GLRFTINKQNVKDIPAIFDLLEKENIPRICFYHLVYAGRGSKMVDEDLSLEDSRKAVDLI
EEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
MQRTRELHEKGFPAEVLTVDNHCDGPYIYLKMLKENPERAAEIFELLSMNQGNSSGIGIG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHCCHHHHHHHHHHHHCCCCCCCCEEEE
CVSWDGSVHADQFWRHYSFGNVRERPFSEIWTDLSDELMAGLKYRKPLIQANGDRCAKCK
EEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCHHCCCCCCCCCEE
WFDVCNGNFRVRAEAVYGNVWADDPACYLTKEEIGYDEA
EEEEECCCEEEEEEEEECCEECCCCCEEEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA