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The map label for this gene is mtnU [H]

Identifier: 21226386

GI number: 21226386

Start: 383733

End: 384653

Strand: Reverse

Name: mtnU [H]

Synonym: MM_0284

Alternate gene names: 21226386

Gene position: 384653-383733 (Counterclockwise)

Preceding gene: 21226387

Following gene: 21226380

Centisome position: 9.39

GC content: 43.76

Gene sequence:

>921_bases
ATGGTCATAAATATGAAAGTTGCCTGTATCCAGATGGATGTGCTTCAGTGTAAGAAGCAGGAAAACCTTGAAAAAGCCCT
CAGCATGGCTCTTAAAGCTGTTGATAAAGGGGCAGAATTAGTCGTTTTTCCCGAAGTTTTTTCCACAGGCTTTTGCTATG
AAAATATTGACCATGCAGCAGAAACCCTTCCCTCTCCTCTTCTTGAGAACCTGGCGTGTTTTTCCGAAGCCAACGACTGC
ATCATCCTGGGTTCTATCATTCTGAAGGATGGCAACGAATCAGGTGAAGAAAAATATTTTAGAGAGGGAGATGCCTGTTT
TTCAGGAAATGAAAATGAGATGCCGGTAAATAAAAATTCCACTGAATATAAAAATTTCACTGAAAATAAAAATTCCGCTG
AAAATAAAAATTCTCCTTATTATAACCTCGGCTTCTGCTTCGAGTCCGGGGCTCTTGCAGGCACTTACCGCAAAACTCAC
CCTTTCAAAGCCGAAAATAAGTATTTCTCAAAAGGCAGTTCGATAGAGCCCATTTCCCTGAAAAAACAAGACCTGAAAAT
CGGCTTTGAGATCTGCTATGAACTCCGCTTTCCCGAGGTCGCAAGAAAACTGGCTCTTGCCGGCTCTGACCTGCTTGTAA
CCACAGCAGCTTTTCCGAATCCCAGGTCCGAACACTGGAAGGTCCTTGCAAAGGCAAGAGCAATAGAAAACCAGATCCCT
CACATCGCCTGCAACCGCACAGGTTCTGCCCCTGACTGCAGTTATTTCGGGCACTCGATGATTATTGATGCCTGGGGAGA
AGTAAAAGCCGATGCAGGAAGCAAAGAATGTGTAATAGTTCATGACCTTGACATGTCCCAGAAAGATGAGGTCCGAAAAT
TAATCCCTGTTTTTGAAGACAGAAGAGTGGAGCTTTACTGA

Upstream 100 bases:

>100_bases
TACCCTGCTGCCCTGAAAGCCTTTATGCAGATTCTTTGCAGGTCCCGAACCCTGAAACCTTTTACCTGTCCGAACCAGGA
ACGATCTTTAATCAAACCTC

Downstream 100 bases:

>100_bases
TACAGTCTTAACCTTTTTCCGGTCATTTCCAGCTGCCTGGCTGATATTCCATATTTGGATATTTTCCGGCGCGGCTAATG
TTTTCAATTTTATATCCAGT

Product: putative amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVINMKVACIQMDVLQCKKQENLEKALSMALKAVDKGAELVVFPEVFSTGFCYENIDHAAETLPSPLLENLACFSEANDC
IILGSIILKDGNESGEEKYFREGDACFSGNENEMPVNKNSTEYKNFTENKNSAENKNSPYYNLGFCFESGALAGTYRKTH
PFKAENKYFSKGSSIEPISLKKQDLKIGFEICYELRFPEVARKLALAGSDLLVTTAAFPNPRSEHWKVLAKARAIENQIP
HIACNRTGSAPDCSYFGHSMIIDAWGEVKADAGSKECVIVHDLDMSQKDEVRKLIPVFEDRRVELY

Sequences:

>Translated_306_residues
MVINMKVACIQMDVLQCKKQENLEKALSMALKAVDKGAELVVFPEVFSTGFCYENIDHAAETLPSPLLENLACFSEANDC
IILGSIILKDGNESGEEKYFREGDACFSGNENEMPVNKNSTEYKNFTENKNSAENKNSPYYNLGFCFESGALAGTYRKTH
PFKAENKYFSKGSSIEPISLKKQDLKIGFEICYELRFPEVARKLALAGSDLLVTTAAFPNPRSEHWKVLAKARAIENQIP
HIACNRTGSAPDCSYFGHSMIIDAWGEVKADAGSKECVIVHDLDMSQKDEVRKLIPVFEDRRVELY
>Mature_306_residues
MVINMKVACIQMDVLQCKKQENLEKALSMALKAVDKGAELVVFPEVFSTGFCYENIDHAAETLPSPLLENLACFSEANDC
IILGSIILKDGNESGEEKYFREGDACFSGNENEMPVNKNSTEYKNFTENKNSAENKNSPYYNLGFCFESGALAGTYRKTH
PFKAENKYFSKGSSIEPISLKKQDLKIGFEICYELRFPEVARKLALAGSDLLVTTAAFPNPRSEHWKVLAKARAIENQIP
HIACNRTGSAPDCSYFGHSMIIDAWGEVKADAGSKECVIVHDLDMSQKDEVRKLIPVFEDRRVELY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=318, Percent_Identity=27.6729559748428, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI297632350, Length=169, Percent_Identity=34.9112426035503, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI297632348, Length=169, Percent_Identity=34.9112426035503, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI5031947, Length=169, Percent_Identity=34.9112426035503, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1786412, Length=300, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556280, Length=179, Percent_Identity=34.0782122905028, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6323383, Length=319, Percent_Identity=24.1379310344828, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322335, Length=196, Percent_Identity=29.0816326530612, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355835, Length=223, Percent_Identity=30.4932735426009, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17933642, Length=171, Percent_Identity=35.672514619883, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 34213; Mature: 34213

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINMKVACIQMDVLQCKKQENLEKALSMALKAVDKGAELVVFPEVFSTGFCYENIDHAA
CEEEEEEHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHHHHH
ETLPSPLLENLACFSEANDCIILGSIILKDGNESGEEKYFREGDACFSGNENEMPVNKNS
HHCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHCCCCEECCCCCCCCCCCCC
TEYKNFTENKNSAENKNSPYYNLGFCFESGALAGTYRKTHPFKAENKYFSKGSSIEPISL
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEECCCCCCCCCCCCCCHHCCCCCCCCCCC
KKQDLKIGFEICYELRFPEVARKLALAGSDLLVTTAAFPNPRSEHWKVLAKARAIENQIP
CHHHHHHEEHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
HIACNRTGSAPDCSYFGHSMIIDAWGEVKADAGSKECVIVHDLDMSQKDEVRKLIPVFED
EEEECCCCCCCCHHHCCCEEEEECCCCEECCCCCCCEEEEEECCCCCHHHHHHHHCHHCC
RRVELY
CEEECC
>Mature Secondary Structure
MVINMKVACIQMDVLQCKKQENLEKALSMALKAVDKGAELVVFPEVFSTGFCYENIDHAA
CEEEEEEHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHHHHH
ETLPSPLLENLACFSEANDCIILGSIILKDGNESGEEKYFREGDACFSGNENEMPVNKNS
HHCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHCCCCEECCCCCCCCCCCCC
TEYKNFTENKNSAENKNSPYYNLGFCFESGALAGTYRKTHPFKAENKYFSKGSSIEPISL
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEECCCCCCCCCCCCCCHHCCCCCCCCCCC
KKQDLKIGFEICYELRFPEVARKLALAGSDLLVTTAAFPNPRSEHWKVLAKARAIENQIP
CHHHHHHEEHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
HIACNRTGSAPDCSYFGHSMIIDAWGEVKADAGSKECVIVHDLDMSQKDEVRKLIPVFED
EEEECCCCCCCCHHHCCCEEEEECCCCEECCCCCCCEEEEEECCCCCHHHHHHHHCHHCC
RRVELY
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]