| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is pcrA [H]
Identifier: 21226292
GI number: 21226292
Start: 261351
End: 264077
Strand: Direct
Name: pcrA [H]
Synonym: MM_0190
Alternate gene names: 21226292
Gene position: 261351-264077 (Clockwise)
Preceding gene: 21226290
Following gene: 21226294
Centisome position: 6.38
GC content: 38.58
Gene sequence:
>2727_bases ATGGGTGATAAAAGATTTCTGGAATTGATAATTAAAGAACCGAAAGAACTATCTGATAGTCAGAAAAAAGCCGTTCTATC AGACAGAAGACATATCAGGATTATTGCTGGAGCTGGCGCCGGGAAAACTGAAACACTCACAAGAAAAATTGTGTGTTTGC TTCTTTACGAAAATGTTAAACCAGCATCTATTGTTGCTTTCACATTTACGGAAAAAGCAGCGCAGGGGATGAAAAGTCGA GTTTATGATCGTGTCCGCCAACTTGGTGGTGAAGAGATATGTGCCAAACTGGGGGAAATGTACATTGGCACAATACATGG TTACTGCTCTTTTTTACTAGAGAACCATTTTAAGTTTGGAGACTATGGAGTTCTTGACGAAAATCAAGAAACTGCTTTTC TAATGCGTGTGGGATGGGAGCTTGGGTTTGGTAAAAATGGAAATTACACCCAGAACTGCCGGACATTTCTTAAAAATCTT AACGTGGTATATGGGGAGCTAATACCAGAAAACAATCTAAAAAAGAAAGCTCCAGAATTCTATAAGTGTTTTAAAAAATA TGAAGAAATCTTAGATTCCCATAAGAGGTTGACATTTAATAGAATGATCAATCTAGCCCTAACAAATTTACAAGAGAAGC AAAACGTACTCTCAGATGTAAAATATCTGATTGTTGACGAATACCAGGATATAAATAGGGCTCAGGAAAAACTTATACAG TTAATAGGACTGAATTCCGAGATTTTTATTGTGGGAGATCCCAGGCAAACTATTTACCAGTGGCGGGGATCAGATGAGAA GTGTTTTGAAGATTTTGCAGTAAAGCACATAGATGCCGAAACTATTTCTATTAATGAAAATAGAAGGAGTGGCAGGCAAA TTATAGAAGTTTCAAATCAGTTCTCAGATTATTTTGAAGATGAATATGACCATCTTGATCCTGTGAGAAAAGAAGAGGGT GCAGTATATATTGCAAAACTTTCGGATAACATCCATGAAGCAAAATGGATTGCGGATCAGATAGAGAAACATGTAGATGC TGGAAAGTGTTCATATGGTGATATTGGAATACTACTTCGCAGTGTAAATACATCAGCGCCTCCATTCATTGATATATTCA GGGAAAGAAACATACCTTTTATTGTAGGAGGTAAAGTTGGTCTTTTCCGCAGGCCTGAAATTCAAACTATGGGCAAACTT TTCGCCTGGCTTTACGATAAAGGATTCTGGTACGAAAGCCAATGGGATCGAGAAAATAAAGAGGAAGGAGAAGAGCTCCT CTATTCTGCACTTGAAAGCTGGAATGATGGAGTTCCTAGCTGTAAATTACATAGCGAAGTAATTAAAAAGCTCGAAAACT GGAAAAAAAATACGCTTGATTCAAAATACGAAAGCTTTACAGAAGTGTACCATGAACTTCTCGTCCTGTTAAATTACCTT AACCTTGATTCAGAAGATCCAAATCATGCTGTGATAATGGCAAACTTGGGAAGGTTTAGCTCTCTTTTAACTGATTTTGA ATCTGCAAATATGCTTGGTGGCAGGCAGAGAAACTGGGAAAGAGATTTGAAGAATCTCTGCTGGTATATGAATAGTTATG CATCAGGCTCTTATGAAGAGCAGCCGGGAGACGACATCCGAGGAGTAGATGCTGTTCAGTTGATGACAGTACACCAAGCA AAGGGACTTGAATGGCCACTGGTCTTTGTCCCAGCTATGAACGCTAGGCGTTTTCCATCGAGTATGGCAGGAAGAGAGCA AACATGGATGATCCCAAGGAATATGTTTGATGCCGAGAAATATGAGGGAGATATAGAGAGTGAAAAGAAACTTTTCTATG TTGCTCTCACGAGGGCAAAGGATGTGCTTGTTGTTAGCCACTTTGGAACGCTAAACGGCAGAAACTCAGGAGAAAGCACT TTTATCAGTGAAGGGCTTCGGGATTCAAAGACTACGAAATTATCTGCAAAAGACGAACTACCTTTGCATGACCTAACAAG TTCCAAAATTTCAGATGAGATACTTACGTACACCCCCTCCGAGATTATCCTATACCGGAAATGCCCTTACTTTTACAGAT TAAACCAAATCTGGGGTTACGAGCCGGGATTCAAAGAGAGAATCGGTTATGGAAATACTCTACATTTCTGCCTTCAGCAA GCAGCAGATCTGATTAAAAATGAAGGGTACAGCCCCATAAGTGCAATTTCAACAGCAGTCGATGAGAATTTCTATATGCC CTTTGTAAATAAGATACAGGGAGAAAAAATAAAGGAAGCAGCTAAGAGAAAGCTCATAAGTTTTGTGAAAAAGCATGAAA CGGATATGCATAATATACAGGAAGTTGAAGCAAGGATAGAGTTTCCACTCCAAAAAGCCACAATTACTGGAAAAATTGAC GTTATAATTCATGATGGAGATCAGCTGGAAGTTCGTGACTATAAAACATCAGATAGCGTTATCACAGAAGCTGAATCTGC CATGCAAATCCAGATGTACTCAATAGGAATGAAAATTCTTGGGGAAAATGTGACTAAGGGTTCTGTAGCATATCTCTCAG ACGCAAAAGTCGCATATGTGGAAGTAGATGATTCCAGACTTGAAGAAACAAAAAAACAAGTAGAAAGACATATAGAGGGA ATAAAAAACCGTAGCTTCAAACCATGTACAGGGGAATTTTGTAATAAGTGTGAACTTACAAAGATATGTAGATGGAAAAA AAGATGA
Upstream 100 bases:
>100_bases ATAATAAAATAAAAAGGTGTTCATAGAACTATAAAAACATCATTCACATTATATGGAAAGAGTGATATATTAAAAAAACA TACTCTGTTTGTGAAAAAAA
Downstream 100 bases:
>100_bases GACATTTATCAAATTTTATGTTTATGCATAATGAAATCAAAAGTTAAAATTGTATAAGTGTTTGGAGGGAATGGTATGAA AGCAATGTTGTTACGTGTTG
Product: DNA helicase II
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 908; Mature: 907
Protein sequence:
>908_residues MGDKRFLELIIKEPKELSDSQKKAVLSDRRHIRIIAGAGAGKTETLTRKIVCLLLYENVKPASIVAFTFTEKAAQGMKSR VYDRVRQLGGEEICAKLGEMYIGTIHGYCSFLLENHFKFGDYGVLDENQETAFLMRVGWELGFGKNGNYTQNCRTFLKNL NVVYGELIPENNLKKKAPEFYKCFKKYEEILDSHKRLTFNRMINLALTNLQEKQNVLSDVKYLIVDEYQDINRAQEKLIQ LIGLNSEIFIVGDPRQTIYQWRGSDEKCFEDFAVKHIDAETISINENRRSGRQIIEVSNQFSDYFEDEYDHLDPVRKEEG AVYIAKLSDNIHEAKWIADQIEKHVDAGKCSYGDIGILLRSVNTSAPPFIDIFRERNIPFIVGGKVGLFRRPEIQTMGKL FAWLYDKGFWYESQWDRENKEEGEELLYSALESWNDGVPSCKLHSEVIKKLENWKKNTLDSKYESFTEVYHELLVLLNYL NLDSEDPNHAVIMANLGRFSSLLTDFESANMLGGRQRNWERDLKNLCWYMNSYASGSYEEQPGDDIRGVDAVQLMTVHQA KGLEWPLVFVPAMNARRFPSSMAGREQTWMIPRNMFDAEKYEGDIESEKKLFYVALTRAKDVLVVSHFGTLNGRNSGEST FISEGLRDSKTTKLSAKDELPLHDLTSSKISDEILTYTPSEIILYRKCPYFYRLNQIWGYEPGFKERIGYGNTLHFCLQQ AADLIKNEGYSPISAISTAVDENFYMPFVNKIQGEKIKEAAKRKLISFVKKHETDMHNIQEVEARIEFPLQKATITGKID VIIHDGDQLEVRDYKTSDSVITEAESAMQIQMYSIGMKILGENVTKGSVAYLSDAKVAYVEVDDSRLEETKKQVERHIEG IKNRSFKPCTGEFCNKCELTKICRWKKR
Sequences:
>Translated_908_residues MGDKRFLELIIKEPKELSDSQKKAVLSDRRHIRIIAGAGAGKTETLTRKIVCLLLYENVKPASIVAFTFTEKAAQGMKSR VYDRVRQLGGEEICAKLGEMYIGTIHGYCSFLLENHFKFGDYGVLDENQETAFLMRVGWELGFGKNGNYTQNCRTFLKNL NVVYGELIPENNLKKKAPEFYKCFKKYEEILDSHKRLTFNRMINLALTNLQEKQNVLSDVKYLIVDEYQDINRAQEKLIQ LIGLNSEIFIVGDPRQTIYQWRGSDEKCFEDFAVKHIDAETISINENRRSGRQIIEVSNQFSDYFEDEYDHLDPVRKEEG AVYIAKLSDNIHEAKWIADQIEKHVDAGKCSYGDIGILLRSVNTSAPPFIDIFRERNIPFIVGGKVGLFRRPEIQTMGKL FAWLYDKGFWYESQWDRENKEEGEELLYSALESWNDGVPSCKLHSEVIKKLENWKKNTLDSKYESFTEVYHELLVLLNYL NLDSEDPNHAVIMANLGRFSSLLTDFESANMLGGRQRNWERDLKNLCWYMNSYASGSYEEQPGDDIRGVDAVQLMTVHQA KGLEWPLVFVPAMNARRFPSSMAGREQTWMIPRNMFDAEKYEGDIESEKKLFYVALTRAKDVLVVSHFGTLNGRNSGEST FISEGLRDSKTTKLSAKDELPLHDLTSSKISDEILTYTPSEIILYRKCPYFYRLNQIWGYEPGFKERIGYGNTLHFCLQQ AADLIKNEGYSPISAISTAVDENFYMPFVNKIQGEKIKEAAKRKLISFVKKHETDMHNIQEVEARIEFPLQKATITGKID VIIHDGDQLEVRDYKTSDSVITEAESAMQIQMYSIGMKILGENVTKGSVAYLSDAKVAYVEVDDSRLEETKKQVERHIEG IKNRSFKPCTGEFCNKCELTKICRWKKR >Mature_907_residues GDKRFLELIIKEPKELSDSQKKAVLSDRRHIRIIAGAGAGKTETLTRKIVCLLLYENVKPASIVAFTFTEKAAQGMKSRV YDRVRQLGGEEICAKLGEMYIGTIHGYCSFLLENHFKFGDYGVLDENQETAFLMRVGWELGFGKNGNYTQNCRTFLKNLN VVYGELIPENNLKKKAPEFYKCFKKYEEILDSHKRLTFNRMINLALTNLQEKQNVLSDVKYLIVDEYQDINRAQEKLIQL IGLNSEIFIVGDPRQTIYQWRGSDEKCFEDFAVKHIDAETISINENRRSGRQIIEVSNQFSDYFEDEYDHLDPVRKEEGA VYIAKLSDNIHEAKWIADQIEKHVDAGKCSYGDIGILLRSVNTSAPPFIDIFRERNIPFIVGGKVGLFRRPEIQTMGKLF AWLYDKGFWYESQWDRENKEEGEELLYSALESWNDGVPSCKLHSEVIKKLENWKKNTLDSKYESFTEVYHELLVLLNYLN LDSEDPNHAVIMANLGRFSSLLTDFESANMLGGRQRNWERDLKNLCWYMNSYASGSYEEQPGDDIRGVDAVQLMTVHQAK GLEWPLVFVPAMNARRFPSSMAGREQTWMIPRNMFDAEKYEGDIESEKKLFYVALTRAKDVLVVSHFGTLNGRNSGESTF ISEGLRDSKTTKLSAKDELPLHDLTSSKISDEILTYTPSEIILYRKCPYFYRLNQIWGYEPGFKERIGYGNTLHFCLQQA ADLIKNEGYSPISAISTAVDENFYMPFVNKIQGEKIKEAAKRKLISFVKKHETDMHNIQEVEARIEFPLQKATITGKIDV IIHDGDQLEVRDYKTSDSVITEAESAMQIQMYSIGMKILGENVTKGSVAYLSDAKVAYVEVDDSRLEETKKQVERHIEGI KNRSFKPCTGEFCNKCELTKICRWKKR
Specific function: Essential helicase [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=654, Percent_Identity=24.9235474006116, Blast_Score=156, Evalue=6e-39, Organism=Escherichia coli, GI48994965, Length=677, Percent_Identity=24.8153618906942, Blast_Score=122, Evalue=1e-28, Organism=Saccharomyces cerevisiae, GI6322369, Length=322, Percent_Identity=28.8819875776398, Blast_Score=106, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6324477, Length=619, Percent_Identity=23.2633279483037, Blast_Score=92, Evalue=3e-19,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 104578; Mature: 104447
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGDKRFLELIIKEPKELSDSQKKAVLSDRRHIRIIAGAGAGKTETLTRKIVCLLLYENVK CCHHHHHHHHHHCCHHCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC PASIVAFTFTEKAAQGMKSRVYDRVRQLGGEEICAKLGEMYIGTIHGYCSFLLENHFKFG CCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC DYGVLDENQETAFLMRVGWELGFGKNGNYTQNCRTFLKNLNVVYGELIPENNLKKKAPEF CCCCCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHH YKCFKKYEEILDSHKRLTFNRMINLALTNLQEKQNVLSDVKYLIVDEYQDINRAQEKLIQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LIGLNSEIFIVGDPRQTIYQWRGSDEKCFEDFAVKHIDAETISINENRRSGRQIIEVSNQ HHCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH FSDYFEDEYDHLDPVRKEEGAVYIAKLSDNIHEAKWIADQIEKHVDAGKCSYGDIGILLR HHHHHHCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHEE SVNTSAPPFIDIFRERNIPFIVGGKVGLFRRPEIQTMGKLFAWLYDKGFWYESQWDRENK CCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCH EEGEELLYSALESWNDGVPSCKLHSEVIKKLENWKKNTLDSKYESFTEVYHELLVLLNYL HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NLDSEDPNHAVIMANLGRFSSLLTDFESANMLGGRQRNWERDLKNLCWYMNSYASGSYEE CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC QPGDDIRGVDAVQLMTVHQAKGLEWPLVFVPAMNARRFPSSMAGREQTWMIPRNMFDAEK CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCEEECCCHHCCHHH YEGDIESEKKLFYVALTRAKDVLVVSHFGTLNGRNSGESTFISEGLRDSKTTKLSAKDEL HCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCEECCCCCC PLHDLTSSKISDEILTYTPSEIILYRKCPYFYRLNQIWGYEPGFKERIGYGNTLHFCLQQ CCHHCCHHHHCCHHHEECCCCEEEEECCCCCEEHHHHCCCCCCHHHHCCCCCHHHHHHHH AADLIKNEGYSPISAISTAVDENFYMPFVNKIQGEKIKEAAKRKLISFVKKHETDMHNIQ HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH EVEARIEFPLQKATITGKIDVIIHDGDQLEVRDYKTSDSVITEAESAMQIQMYSIGMKIL HHHHHHHCCHHHEEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHEEHHHHHHHHHH GENVTKGSVAYLSDAKVAYVEVDDSRLEETKKQVERHIEGIKNRSFKPCTGEFCNKCELT CCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHH KICRWKKR HHHCCCCC >Mature Secondary Structure GDKRFLELIIKEPKELSDSQKKAVLSDRRHIRIIAGAGAGKTETLTRKIVCLLLYENVK CHHHHHHHHHHCCHHCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC PASIVAFTFTEKAAQGMKSRVYDRVRQLGGEEICAKLGEMYIGTIHGYCSFLLENHFKFG CCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC DYGVLDENQETAFLMRVGWELGFGKNGNYTQNCRTFLKNLNVVYGELIPENNLKKKAPEF CCCCCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHH YKCFKKYEEILDSHKRLTFNRMINLALTNLQEKQNVLSDVKYLIVDEYQDINRAQEKLIQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LIGLNSEIFIVGDPRQTIYQWRGSDEKCFEDFAVKHIDAETISINENRRSGRQIIEVSNQ HHCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH FSDYFEDEYDHLDPVRKEEGAVYIAKLSDNIHEAKWIADQIEKHVDAGKCSYGDIGILLR HHHHHHCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHEE SVNTSAPPFIDIFRERNIPFIVGGKVGLFRRPEIQTMGKLFAWLYDKGFWYESQWDRENK CCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCH EEGEELLYSALESWNDGVPSCKLHSEVIKKLENWKKNTLDSKYESFTEVYHELLVLLNYL HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NLDSEDPNHAVIMANLGRFSSLLTDFESANMLGGRQRNWERDLKNLCWYMNSYASGSYEE CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC QPGDDIRGVDAVQLMTVHQAKGLEWPLVFVPAMNARRFPSSMAGREQTWMIPRNMFDAEK CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCEEECCCHHCCHHH YEGDIESEKKLFYVALTRAKDVLVVSHFGTLNGRNSGESTFISEGLRDSKTTKLSAKDEL HCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCEECCCCCC PLHDLTSSKISDEILTYTPSEIILYRKCPYFYRLNQIWGYEPGFKERIGYGNTLHFCLQQ CCHHCCHHHHCCHHHEECCCCEEEEECCCCCEEHHHHCCCCCCHHHHCCCCCHHHHHHHH AADLIKNEGYSPISAISTAVDENFYMPFVNKIQGEKIKEAAKRKLISFVKKHETDMHNIQ HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH EVEARIEFPLQKATITGKIDVIIHDGDQLEVRDYKTSDSVITEAESAMQIQMYSIGMKIL HHHHHHHCCHHHEEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHEEHHHHHHHHHH GENVTKGSVAYLSDAKVAYVEVDDSRLEETKKQVERHIEGIKNRSFKPCTGEFCNKCELT CCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHH KICRWKKR HHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA