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The map label for this gene is comDE [H]

Identifier: 21226236

GI number: 21226236

Start: 166296

End: 167453

Strand: Direct

Name: comDE [H]

Synonym: MM_0134

Alternate gene names: 21226236

Gene position: 166296-167453 (Clockwise)

Preceding gene: 21226235

Following gene: 21226239

Centisome position: 4.06

GC content: 46.89

Gene sequence:

>1158_bases
ATGTTAAACCCGGAAGAAGAAGTAATAACACTCATGAAAAAAGCAGGGATTGACCTCGTGGCAACCCTGCCCTGTGACAG
GATTAAAAATCTGCTTCCCCTGGTCTCAAAAAATTTTCCAGAAATCAAGATGACAAGGGAAGAAAACGGGGTGGGAATTT
GCGCCGGGTTCTATCTTGCAGGCGGAAAGCCCTTAATGCTGATTCAAAGCACAGGGCTGGGGAATATGATCAATGCCCTT
GAATCCCTGAACGTGACCTGTAAAATACCCCTGCCTGTCCTGACGAGCTGGCGTGGTGTTTACAAAGAAGCAATTGAAGC
CCAGGTTCCTCTCGGAGTCCACCTGCCTGCGATTCTTGAAGGGGCAGGGCTTGCATACACAATAATCGATGAGGTTGAAA
AACTCCACCAGATTGAAAATGTAATCAGTGACGCCTTTGAAAATTCCAGGCCCCATATAGCCCTGATCTCCCCAAAAGTC
TGGGAAGCTTCAGAGTGCTGCGCCTGGCAGGGTGCAGGAATGCCAGAAAAGCCGGAGGTTATGGAAAGGACATGCAGTAT
TTTCCTCAAAAAAGAGGTCCTCAAGCCGGTAATGCTGAGAAACGATGCCATCTGCGCAATAGCTTCAGAGCTTGATGACG
AAGTTACTGTAACAAACCTGGGAGTCCCCTGCAAGGAACTTTATGCCTGTAAAGACAGGGACCTTAATTTCTATATGTTT
GGCTCAATGGGGCTTGTCTCTTCCATAGGTATGGGAATTGCCCTCCGTTCCGAAAAAACAGTTGTCGCTTTTGACGGAGA
CGGAAGCCTGCTTATGAACCCAAATGCCCTTCTTGAGATTGCAAAAGAATCCCCGAAAAACCTCATTATTATTGCCCTTG
ATAACGGCGCCTACGGGTCTACAGGTTCCCAGGAAACCTGCGCTCTCAGGTACATTGACCTCGAAATATTTGCAAACGCC
TGCGGGATCACAAACACAGCCAAAGTAAATGCCAGAGAAGAACTGATAAAAATATTCAAAAAGTTTAGAGACATGAAAGA
GCTGGCTTTGATCCACGTAATCCTGAAGCCGGGAAATACAAACGCTCCAAACATTCCACTGAGCCCCGAAGGTGCCGCAA
AGCGATTCAAAGAAGCCCTTGAAGCAAAAAAGAATTAA

Upstream 100 bases:

>100_bases
AAAAAACATAACAAAAATCTGTGTAAATCTGTTAATAGAAACCTGTAAGAAAAACAGGCTCAGAATACTCATAAGCATAA
GCACGTCAGAAGGTATAGGC

Downstream 100 bases:

>100_bases
AAGGGTTTGATTCAGGCTTATTGAGATTTGATCAGGGGTTAATCTCTCAAGCTTTATTCTTTAACCCTTTATTCTCTCCA
GCTTATTTTCTCAACCGGTT

Product: sulfopyruvate decarboxylase subunit alpha

Products: NA

Alternate protein names: SpyrDC [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLNPEEEVITLMKKAGIDLVATLPCDRIKNLLPLVSKNFPEIKMTREENGVGICAGFYLAGGKPLMLIQSTGLGNMINAL
ESLNVTCKIPLPVLTSWRGVYKEAIEAQVPLGVHLPAILEGAGLAYTIIDEVEKLHQIENVISDAFENSRPHIALISPKV
WEASECCAWQGAGMPEKPEVMERTCSIFLKKEVLKPVMLRNDAICAIASELDDEVTVTNLGVPCKELYACKDRDLNFYMF
GSMGLVSSIGMGIALRSEKTVVAFDGDGSLLMNPNALLEIAKESPKNLIIIALDNGAYGSTGSQETCALRYIDLEIFANA
CGITNTAKVNAREELIKIFKKFRDMKELALIHVILKPGNTNAPNIPLSPEGAAKRFKEALEAKKN

Sequences:

>Translated_385_residues
MLNPEEEVITLMKKAGIDLVATLPCDRIKNLLPLVSKNFPEIKMTREENGVGICAGFYLAGGKPLMLIQSTGLGNMINAL
ESLNVTCKIPLPVLTSWRGVYKEAIEAQVPLGVHLPAILEGAGLAYTIIDEVEKLHQIENVISDAFENSRPHIALISPKV
WEASECCAWQGAGMPEKPEVMERTCSIFLKKEVLKPVMLRNDAICAIASELDDEVTVTNLGVPCKELYACKDRDLNFYMF
GSMGLVSSIGMGIALRSEKTVVAFDGDGSLLMNPNALLEIAKESPKNLIIIALDNGAYGSTGSQETCALRYIDLEIFANA
CGITNTAKVNAREELIKIFKKFRDMKELALIHVILKPGNTNAPNIPLSPEGAAKRFKEALEAKKN
>Mature_385_residues
MLNPEEEVITLMKKAGIDLVATLPCDRIKNLLPLVSKNFPEIKMTREENGVGICAGFYLAGGKPLMLIQSTGLGNMINAL
ESLNVTCKIPLPVLTSWRGVYKEAIEAQVPLGVHLPAILEGAGLAYTIIDEVEKLHQIENVISDAFENSRPHIALISPKV
WEASECCAWQGAGMPEKPEVMERTCSIFLKKEVLKPVMLRNDAICAIASELDDEVTVTNLGVPCKELYACKDRDLNFYMF
GSMGLVSSIGMGIALRSEKTVVAFDGDGSLLMNPNALLEIAKESPKNLIIIALDNGAYGSTGSQETCALRYIDLEIFANA
CGITNTAKVNAREELIKIFKKFRDMKELALIHVILKPGNTNAPNIPLSPEGAAKRFKEALEAKKN

Specific function: Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate [H]

COG id: COG4032

COG function: function code R; Predicted thiamine-pyrophosphate-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022502
- InterPro:   IPR022494
- InterPro:   IPR012001
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.79 [H]

Molecular weight: Translated: 41989; Mature: 41989

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPEEEVITLMKKAGIDLVATLPCDRIKNLLPLVSKNFPEIKMTREENGVGICAGFYLA
CCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEC
GGKPLMLIQSTGLGNMINALESLNVTCKIPLPVLTSWRGVYKEAIEAQVPLGVHLPAILE
CCCEEEEEECCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEECHHHHC
GAGLAYTIIDEVEKLHQIENVISDAFENSRPHIALISPKVWEASECCAWQGAGMPEKPEV
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCCCCCCCCHHH
MERTCSIFLKKEVLKPVMLRNDAICAIASELDDEVTVTNLGVPCKELYACKDRDLNFYMF
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEEE
GSMGLVSSIGMGIALRSEKTVVAFDGDGSLLMNPNALLEIAKESPKNLIIIALDNGAYGS
CCCHHHHHCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHCCCCCEEEEEECCCCCCC
TGSQETCALRYIDLEIFANACGITNTAKVNAREELIKIFKKFRDMKELALIHVILKPGNT
CCCCCEEEEEEEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
NAPNIPLSPEGAAKRFKEALEAKKN
CCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNPEEEVITLMKKAGIDLVATLPCDRIKNLLPLVSKNFPEIKMTREENGVGICAGFYLA
CCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEC
GGKPLMLIQSTGLGNMINALESLNVTCKIPLPVLTSWRGVYKEAIEAQVPLGVHLPAILE
CCCEEEEEECCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEECHHHHC
GAGLAYTIIDEVEKLHQIENVISDAFENSRPHIALISPKVWEASECCAWQGAGMPEKPEV
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCCCCCCCCHHH
MERTCSIFLKKEVLKPVMLRNDAICAIASELDDEVTVTNLGVPCKELYACKDRDLNFYMF
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEEE
GSMGLVSSIGMGIALRSEKTVVAFDGDGSLLMNPNALLEIAKESPKNLIIIALDNGAYGS
CCCHHHHHCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHCCCCCEEEEEECCCCCCC
TGSQETCALRYIDLEIFANACGITNTAKVNAREELIKIFKKFRDMKELALIHVILKPGNT
CCCCCEEEEEEEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
NAPNIPLSPEGAAKRFKEALEAKKN
CCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]