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The map label for this gene is aceB [H]

Identifier: 209695863

GI number: 209695863

Start: 2611482

End: 2613086

Strand: Reverse

Name: aceB [H]

Synonym: VSAL_I2439

Alternate gene names: 209695863

Gene position: 2613086-2611482 (Counterclockwise)

Preceding gene: 209695864

Following gene: 209695862

Centisome position: 78.59

GC content: 41.0

Gene sequence:

>1605_bases
ATGACAGATACCATGACAACCACAGAACAATCACTCTCAATAATTGCTCCTAATAGCTTACAAAGAGAAGAAATATTAAC
GTCTGGCGCAATACGTTTCCTTACTCATGTTGTCGATAAGTTTGCTCACCGCATTCCAGAATTACTTAATACTCGTCAGG
ATCGTCAGAGACAAATTGATGCAGGCCAATTGCCCGATTTTTTACAAGAAACGCGCTCTATTCGAGAATCTGAATGGACG
ATTCAAGGGATACCCACTGACCTTCAAGACCGAAGAGTTGAAATTACTGGACCGACAGATAGAAAAATGGTGATCAATGC
ATTGAATGCGAATGTAAAAGTATTCATGGCCGATTTTGAAGATTCATTAGCACCTTCTTGGGAGGCTGTGCTAGATGGAC
AGATAAACCTGAGAGATGCAATGAACGGCACGATTCAGTACACCAACCCAGAAACGGGGAAGGTGTACCAACTAAAACAA
GATCCTGCTGTATTGATTTGTCGCGTTCGTGGTCTACATCTTCCTGAAAAACATGTGCTATTTAATGGTGTACCTATTCC
CGGTGCTTTATTTGATTTTGCTCTCTATTTTTACCACAATTATCAAACGTCATTAAAGAAAGGCAGTGGTCCTTACTTTT
ATCTGCCTAAATTACAAGCTTACCAAGAAGCCGCGTGGTGGAGTGATGTGTTTAGTTTTGCAGAGCGAGAATTCGGATTA
AAGCAAGGCACAATAAAAGCAACAGTATTGATTGAAACATTGCCTGCTGTGTTTGAGATGGATGAAATATTATATAGCCT
TAAAGAGCATATTGTTGGATTGAACTGTGGTCGATGGGATTACATTTTTAGCTACATTAAAACACTTAAAAATCATCCCG
ACCGTGTATTGCCCGATCGCCAAGCGGTGACAATGGAAAAACCGTTTTTAAATGCCTATTCACGATTACTGATCAGAACC
TGTCACCGAAGAGCCGCATTTGCGATGGGAGGAATGGCCGCCTTTATTCCATCAAAAGACCCGGTAAAAAATGATTGGGT
TTTAAATAAAATTAAAACGGATAAATCATTAGAAGCAAATAATGGACACGACGGAAGTTGGGTTGCTCATCCGGGACTGG
CTGATACCGCAAGAGCTGAATTTGACAAGGTATTGGGTGAGCGCTCTAACCAGTTAGACATTAGCCGAGATACTGATGCG
CCAATTACGGCTGAAGAACTATTAGCACGGTGTGAAGGCGAAAGAACAGAAGAGGGAATGCGTCATAATATTCGAGTCGC
AGTTCAATACATTGAAGCGTGGATAACGGGTAATGGATGCGTCCCTATTTATGGATTAATGGAAGATGCCGCAACGGCAG
AAATATCACGAACGTCTATTTGGCAATGGATACAACATGGAAAGACACTAGATAACGGTGACACAGTGACCGCGGATCTG
TTTAGAACCATGTTATTAGAAGAAATGAAAATAATAGAAGAGGAGTTGGGAACTGAACGTTTTGATTCAGGACAATTTAT
TCAAGCAGCAAAACTGATGGAGCAATTAACCACCAGCGATCAACTAACGGACTTTTTAACACTCACTGGCTATGACTATT
TATAA

Upstream 100 bases:

>100_bases
TGTAATAGGAGTTCACGGAAAAACAGTTTAATAGGATGAGACATAAAAACTAAAAGGTAGTTTTTTAGTTACAAATGTAA
TTTTGCCGGAGGCGTAAACT

Downstream 100 bases:

>100_bases
AAGAGGGAACTATTATGACTACATTTAAACCGCAAACTCGCCAACAGCAAATTGATGCGTTAAAAAAAGATTGGGCTGAA
AATCCTCGTTGGAATGGGGT

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTDTMTTTEQSLSIIAPNSLQREEILTSGAIRFLTHVVDKFAHRIPELLNTRQDRQRQIDAGQLPDFLQETRSIRESEWT
IQGIPTDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSLAPSWEAVLDGQINLRDAMNGTIQYTNPETGKVYQLKQ
DPAVLICRVRGLHLPEKHVLFNGVPIPGALFDFALYFYHNYQTSLKKGSGPYFYLPKLQAYQEAAWWSDVFSFAEREFGL
KQGTIKATVLIETLPAVFEMDEILYSLKEHIVGLNCGRWDYIFSYIKTLKNHPDRVLPDRQAVTMEKPFLNAYSRLLIRT
CHRRAAFAMGGMAAFIPSKDPVKNDWVLNKIKTDKSLEANNGHDGSWVAHPGLADTARAEFDKVLGERSNQLDISRDTDA
PITAEELLARCEGERTEEGMRHNIRVAVQYIEAWITGNGCVPIYGLMEDAATAEISRTSIWQWIQHGKTLDNGDTVTADL
FRTMLLEEMKIIEEELGTERFDSGQFIQAAKLMEQLTTSDQLTDFLTLTGYDYL

Sequences:

>Translated_534_residues
MTDTMTTTEQSLSIIAPNSLQREEILTSGAIRFLTHVVDKFAHRIPELLNTRQDRQRQIDAGQLPDFLQETRSIRESEWT
IQGIPTDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSLAPSWEAVLDGQINLRDAMNGTIQYTNPETGKVYQLKQ
DPAVLICRVRGLHLPEKHVLFNGVPIPGALFDFALYFYHNYQTSLKKGSGPYFYLPKLQAYQEAAWWSDVFSFAEREFGL
KQGTIKATVLIETLPAVFEMDEILYSLKEHIVGLNCGRWDYIFSYIKTLKNHPDRVLPDRQAVTMEKPFLNAYSRLLIRT
CHRRAAFAMGGMAAFIPSKDPVKNDWVLNKIKTDKSLEANNGHDGSWVAHPGLADTARAEFDKVLGERSNQLDISRDTDA
PITAEELLARCEGERTEEGMRHNIRVAVQYIEAWITGNGCVPIYGLMEDAATAEISRTSIWQWIQHGKTLDNGDTVTADL
FRTMLLEEMKIIEEELGTERFDSGQFIQAAKLMEQLTTSDQLTDFLTLTGYDYL
>Mature_533_residues
TDTMTTTEQSLSIIAPNSLQREEILTSGAIRFLTHVVDKFAHRIPELLNTRQDRQRQIDAGQLPDFLQETRSIRESEWTI
QGIPTDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSLAPSWEAVLDGQINLRDAMNGTIQYTNPETGKVYQLKQD
PAVLICRVRGLHLPEKHVLFNGVPIPGALFDFALYFYHNYQTSLKKGSGPYFYLPKLQAYQEAAWWSDVFSFAEREFGLK
QGTIKATVLIETLPAVFEMDEILYSLKEHIVGLNCGRWDYIFSYIKTLKNHPDRVLPDRQAVTMEKPFLNAYSRLLIRTC
HRRAAFAMGGMAAFIPSKDPVKNDWVLNKIKTDKSLEANNGHDGSWVAHPGLADTARAEFDKVLGERSNQLDISRDTDAP
ITAEELLARCEGERTEEGMRHNIRVAVQYIEAWITGNGCVPIYGLMEDAATAEISRTSIWQWIQHGKTLDNGDTVTADLF
RTMLLEEMKIIEEELGTERFDSGQFIQAAKLMEQLTTSDQLTDFLTLTGYDYL

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=534, Percent_Identity=72.8464419475655, Blast_Score=816, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=537, Percent_Identity=49.9068901303538, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71982926, Length=431, Percent_Identity=51.9721577726218, Blast_Score=424, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322222, Length=525, Percent_Identity=45.7142857142857, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6324212, Length=525, Percent_Identity=45.3333333333333, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 60687; Mature: 60555

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTMTTTEQSLSIIAPNSLQREEILTSGAIRFLTHVVDKFAHRIPELLNTRQDRQRQID
CCCCCCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
AGQLPDFLQETRSIRESEWTIQGIPTDLQDRRVEITGPTDRKMVINALNANVKVFMADFE
CCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHEECCCEEEEEECCC
DSLAPSWEAVLDGQINLRDAMNGTIQYTNPETGKVYQLKQDPAVLICRVRGLHLPEKHVL
CCCCCCHHHHHCCCEEEHHCCCCCEEECCCCCCCEEEECCCCEEEEEEECCCCCCCHHHE
FNGVPIPGALFDFALYFYHNYQTSLKKGSGPYFYLPKLQAYQEAAWWSDVFSFAEREFGL
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
KQGTIKATVLIETLPAVFEMDEILYSLKEHIVGLNCGRWDYIFSYIKTLKNHPDRVLPDR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
QAVTMEKPFLNAYSRLLIRTCHRRAAFAMGGMAAFIPSKDPVKNDWVLNKIKTDKSLEAN
CCEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHCCCCCCCCC
NGHDGSWVAHPGLADTARAEFDKVLGERSNQLDISRDTDAPITAEELLARCEGERTEEGM
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHH
RHNIRVAVQYIEAWITGNGCVPIYGLMEDAATAEISRTSIWQWIQHGKTLDNGDTVTADL
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FRTMLLEEMKIIEEELGTERFDSGQFIQAAKLMEQLTTSDQLTDFLTLTGYDYL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDTMTTTEQSLSIIAPNSLQREEILTSGAIRFLTHVVDKFAHRIPELLNTRQDRQRQID
CCCCCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
AGQLPDFLQETRSIRESEWTIQGIPTDLQDRRVEITGPTDRKMVINALNANVKVFMADFE
CCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHEECCCEEEEEECCC
DSLAPSWEAVLDGQINLRDAMNGTIQYTNPETGKVYQLKQDPAVLICRVRGLHLPEKHVL
CCCCCCHHHHHCCCEEEHHCCCCCEEECCCCCCCEEEECCCCEEEEEEECCCCCCCHHHE
FNGVPIPGALFDFALYFYHNYQTSLKKGSGPYFYLPKLQAYQEAAWWSDVFSFAEREFGL
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
KQGTIKATVLIETLPAVFEMDEILYSLKEHIVGLNCGRWDYIFSYIKTLKNHPDRVLPDR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
QAVTMEKPFLNAYSRLLIRTCHRRAAFAMGGMAAFIPSKDPVKNDWVLNKIKTDKSLEAN
CCEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHCCCCCCCCC
NGHDGSWVAHPGLADTARAEFDKVLGERSNQLDISRDTDAPITAEELLARCEGERTEEGM
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHH
RHNIRVAVQYIEAWITGNGCVPIYGLMEDAATAEISRTSIWQWIQHGKTLDNGDTVTADL
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FRTMLLEEMKIIEEELGTERFDSGQFIQAAKLMEQLTTSDQLTDFLTLTGYDYL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]