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The map label for this gene is accA

Identifier: 209695835

GI number: 209695835

Start: 2578658

End: 2579617

Strand: Reverse

Name: accA

Synonym: VSAL_I2411

Alternate gene names: 209695835

Gene position: 2579617-2578658 (Counterclockwise)

Preceding gene: 209695836

Following gene: 209695834

Centisome position: 77.58

GC content: 39.48

Gene sequence:

>960_bases
ATGAGCCTAAATTTTCTTGAATTTGAAAAACCAATTGCAGAACTAGAAGCTAAAATTGAAGCGCTGCGTGATATTTCTCG
TCGTGGTGGTGATAATGCACTTGATCTAGATAAAGAAATTAAGCAATTAGAAGATAAATGTTTAGATCTTAAAAAGAAAA
CATTTAGTGATTTAGGTGCGTGGGAAGTTGCTCAACTTGCTCGTCACCCAGAACGTCCATATGTATTAGATTACATTGAA
CTTATGTTTACTGAGTTTGATGAATTAGCCGGTGATCGTGCTTTTGCTGATGATAAAGCATTAGTGGGTGGTATGGCTCG
TTTAGATGGCCGTCCTGTGATGATAATTGGTCATCAAAAAGGACGTGGCACGAAAGAAAAAGTACGTCGCAATTTTGGTA
TGCCAAAACCTGAAGGTTACCGTAAGGCAAAACGTTTAATGCAAATGGCTGAGCGTTTTAAAATGCCGATCATTACTTTT
ATTGATACTGCTGGTGCTTATCCAGGTGTTGGTGCTGAAGAACGTGGTCAATCTGAAGCCATTGCTACGAACCTTAAAAT
CATGTCTGAGCTAAGTGTTCCTGTGATTTGTAATGTTGTTGGTGAAGGCGGTTCTGGTGGTGCTCTTGCTATCGGTGTAG
GTGATTATGTTAACATGCTTCAATACTCTACGTATTCAGTGATTTCTCCTGAAGGTTGTGCTTCAATTTTATGGCGTGAT
TCAGATAAAGCACCTCAAGCGGCTGAAGCAATGGGACTTGTTGCTCCTCGTTTAAAAGAGCTAGAGTTGATTGATACGAT
CATTGATGAACCATTAGGTGGTGCGCATCGTAATCATAAAGCAACGGCTGAGAATATTAAGCAACGTTTAATTGAACAAT
TGAACGAGCTTGAAGGTTTTGATGAAGAAGCGTTGCTTGAACGTCGTTATCAACGTTTAATGAATTACGGTTACTGCTAA

Upstream 100 bases:

>100_bases
TTTGAAGTCGTTGCTTGGCGAACAGCAAGTCGAGCTTGAATTTAACTAGAATAAGTAAGGCTGCTAATTTGAGCGGCCTT
GAACTAACAAGGATTCTTTA

Downstream 100 bases:

>100_bases
TAATTATGAGTAAAGTTCGGAACTAGATTCGCGAATTTTAATAATATAGAGTAAAGTGAAAACGAGCCTTAGTGCTCGTT
TTTTTCATTTTTAGGTTTTA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLNFLEFEKPIAELEAKIEALRDISRRGGDNALDLDKEIKQLEDKCLDLKKKTFSDLGAWEVAQLARHPERPYVLDYIE
LMFTEFDELAGDRAFADDKALVGGMARLDGRPVMIIGHQKGRGTKEKVRRNFGMPKPEGYRKAKRLMQMAERFKMPIITF
IDTAGAYPGVGAEERGQSEAIATNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRNHKATAENIKQRLIEQLNELEGFDEEALLERRYQRLMNYGYC

Sequences:

>Translated_319_residues
MSLNFLEFEKPIAELEAKIEALRDISRRGGDNALDLDKEIKQLEDKCLDLKKKTFSDLGAWEVAQLARHPERPYVLDYIE
LMFTEFDELAGDRAFADDKALVGGMARLDGRPVMIIGHQKGRGTKEKVRRNFGMPKPEGYRKAKRLMQMAERFKMPIITF
IDTAGAYPGVGAEERGQSEAIATNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRNHKATAENIKQRLIEQLNELEGFDEEALLERRYQRLMNYGYC
>Mature_318_residues
SLNFLEFEKPIAELEAKIEALRDISRRGGDNALDLDKEIKQLEDKCLDLKKKTFSDLGAWEVAQLARHPERPYVLDYIEL
MFTEFDELAGDRAFADDKALVGGMARLDGRPVMIIGHQKGRGTKEKVRRNFGMPKPEGYRKAKRLMQMAERFKMPIITFI
DTAGAYPGVGAEERGQSEAIATNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDS
DKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRNHKATAENIKQRLIEQLNELEGFDEEALLERRYQRLMNYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=73.0407523510972, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_ALISL (B6EJW4)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263765.1
- GeneID:   6989298
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2411
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35587; Mature: 35456

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLEFEKPIAELEAKIEALRDISRRGGDNALDLDKEIKQLEDKCLDLKKKTFSDLGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
WEVAQLARHPERPYVLDYIELMFTEFDELAGDRAFADDKALVGGMARLDGRPVMIIGHQK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRGTKEKVRRNFGMPKPEGYRKAKRLMQMAERFKMPIITFIDTAGAYPGVGAEERGQSEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCCCHHCCCHHH
IATNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRNHKATAENIKQRLIEQLNELEGF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DEEALLERRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNFLEFEKPIAELEAKIEALRDISRRGGDNALDLDKEIKQLEDKCLDLKKKTFSDLGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
WEVAQLARHPERPYVLDYIELMFTEFDELAGDRAFADDKALVGGMARLDGRPVMIIGHQK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRGTKEKVRRNFGMPKPEGYRKAKRLMQMAERFKMPIITFIDTAGAYPGVGAEERGQSEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCCCHHCCCHHH
IATNLKIMSELSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDTIIDEPLGGAHRNHKATAENIKQRLIEQLNELEGF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DEEALLERRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA