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The map label for this gene is argS

Identifier: 209695554

GI number: 209695554

Start: 2258762

End: 2260495

Strand: Direct

Name: argS

Synonym: VSAL_I2110

Alternate gene names: 209695554

Gene position: 2258762-2260495 (Clockwise)

Preceding gene: 209695552

Following gene: 209695556

Centisome position: 67.93

GC content: 42.85

Gene sequence:

>1734_bases
TTGAATATTCAATCACTTATTAACGACAAAGTTTCTCAAGCGTTAGAAGCAGCCGGCGCGCCAGCGGGCAGCCCTGCCGC
CGTTCGTCAATCTGCAAAAGCTCAATTTGGTGACTACCAAGCTAACGGCGTAATGGGCGTAGCTAAGCGACTAGGTACAA
ACCCGCGAGAATTTGCTCAGAAAGTACTGGATGTTTTAGATCTTGATGGCATCGCTAGCAAAACTGAAATTGCAGGCCCT
GGCTTCATTAACATTTTCTTGTCTGAAGAATTTCTAGCTAAGCAAGCAGAAGCAGCTTTAGCTGACGAACGTCTAGGCGT
AGCACTAGAAACCAAACAAAATATCGTAGCCGATTACTCAGCACCAAACGTTGCTAAAGAAATGCACGTAGGTCACCTTC
GTTCAACCATCATTGGTGATGCTGTTGTTCGTACTCTTGAGTTTTTAGGCCACAACGTGACTCGTGCTAACCACATCGGT
GACTGGGGTACTCAGTTTGGTATGCTTATCGCAAACCTTGAGCGCATCCAAAAAGAGAAAGGCGAAGTTTCTATGGAACT
GTCTGATCTTGAAGGTTTCTACCGTGAATCTAAAAAACTGTACGACGAAGATGAAGAGTTTGCCGTAACGGCCCGTGGTT
ACGTTGTAAAACTTCAAGGTGGCGACGCTTTCTGTGCAGACATGTGGAAAAAATTAGTCGACGTTACAATGGTTCAAAAC
CAACGTAATTATGACCGTCTAAACGTATCATTAACTCGTGATAACGTGATGGGCGAAAGTATGTATAACAGCATGCTTGC
ACCTATTGTTGCTGATCTTCAAGAAAAAGGCCTAGCAGTAGAAAGTGATGGCGCTCAAGTTGTTTACCTTGACGAATACA
AGAACAAAGATGGCGATCCAATGGGTGTTATCGTTCAAAAACGTGATGGTGGCTTCCTTTACACAACAACAGATATTGCT
TGTGCTAAATACCGTTTCGAAGAACTGAACGCAGATCGCGTACTTTACTTCATCGATTCACGTCAACACCAACACCTAAT
GCAAGCATGGACTATCGTTCGTAAAGCAGGTTATGTTCCTGAGAGCGTATCTTTAGAACACCACGCGTTTGGCATGATGC
TAGGTAAAGATGGTCGTCCATTCAAAACTCGTGCCGGTGGCACCGTTCGTCTTGCTGATCTTCTTGATGAAGCAGAGCAA
CGCGCAATTGCACTGATCGAAGAGAAAAACAAAGATCTATCAACTGAAGAAAAAGCAAAAATTGCAACGACCGTCGCAAT
GGCTGCCGTGAAGTACTCAGATCTTTCTAAGCACCGTACAACCGATTACATCTTTGATTGGGACAACATACTTGCCTTTG
AAGGTAATACTGCCCCTTATATGCAATATGCTTACACTCGTGTAGCATCTATCTTCAGCAAAGCAGACCTATCTATGGAT
AATCTAGCGGGCGAAGTTAAGATCACTGATGAGAAAGAGAAAGCATTAATTACTAAATTAATGCAGTTTGAAGAAGCAGT
ACAAGCAGTAGCAAGTGAAGGTCAACCTCACTTAATGTGTGCGTACTTATTTGAACTTGCTGGCCAGTTCTCTAGCTTCT
ATGAAGCCTGTCCAATTCTAAACAACGACGATGAATCAATTAAACAAAGTCGTCTAAAATTGGCTGCATTAACAGCAAAA
ACAATCAAACAAGGTTTAGATTTATTAGGTATTGAAACGCTAGAGCGTATGTAA

Upstream 100 bases:

>100_bases
GAAACTATTAAATATCCCCTATTTTATTGCTATTATTAGCGACTATTTTGCTTTCCATGCAACAGCATTCCTGTTTAACA
GCGATATGAAGGATAACTCT

Downstream 100 bases:

>100_bases
TCTCTATCTAAACCATAAGATCAAAAAAAGGAGCTAATTAGCTCCTTTTTTTATTTCTAGATTTATTGTAATAAAGTATT
AAAACCAACGTTCTAATGCT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVALETKQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQGGDAFCADMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQEKGLAVESDGAQVVYLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEQ
RAIALIEEKNKDLSTEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNILAFEGNTAPYMQYAYTRVASIFSKADLSMD
NLAGEVKITDEKEKALITKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNDDESIKQSRLKLAALTAK
TIKQGLDLLGIETLERM

Sequences:

>Translated_577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVALETKQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQGGDAFCADMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQEKGLAVESDGAQVVYLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEQ
RAIALIEEKNKDLSTEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNILAFEGNTAPYMQYAYTRVASIFSKADLSMD
NLAGEVKITDEKEKALITKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNDDESIKQSRLKLAALTAK
TIKQGLDLLGIETLERM
>Mature_577_residues
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQKVLDVLDLDGIASKTEIAGP
GFINIFLSEEFLAKQAEAALADERLGVALETKQNIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIG
DWGTQFGMLIANLERIQKEKGEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQGGDAFCADMWKKLVDVTMVQN
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQEKGLAVESDGAQVVYLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEQ
RAIALIEEKNKDLSTEEKAKIATTVAMAAVKYSDLSKHRTTDYIFDWDNILAFEGNTAPYMQYAYTRVASIFSKADLSMD
NLAGEVKITDEKEKALITKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPILNNDDESIKQSRLKLAALTAK
TIKQGLDLLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=596, Percent_Identity=38.4228187919463, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI197100773, Length=528, Percent_Identity=28.219696969697, Blast_Score=210, Evalue=3e-54,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=71.1571675302245, Blast_Score=859, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=37.3109243697479, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=38.3658969804618, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17532153, Length=483, Percent_Identity=27.1221532091097, Blast_Score=152, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=551, Percent_Identity=31.2159709618875, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321883, Length=527, Percent_Identity=28.6527514231499, Blast_Score=220, Evalue=4e-58,
Organism=Drosophila melanogaster, GI18859963, Length=564, Percent_Identity=38.1205673758865, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=30.8488612836439, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ALISL (B6EI57)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263483.1
- ProteinModelPortal:   B6EI57
- GeneID:   6987595
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2110
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63968; Mature: 63968

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLDLDGIASKTEIAGPGFINIFLSEEFLAKQAEAALADERLGVALETKQNIVADYS
HHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEECCCCCEECCC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIGDWGTQFGMLIANLERIQKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQGGDAFCADMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQEKGLAVESDGAQVVYLDEYKNKDGDP
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRFEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEQRAIALIEEKNKDLSTEEKAK
CCCCCCHHHEEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IATTVAMAAVKYSDLSKHRTTDYIFDWDNILAFEGNTAPYMQYAYTRVASIFSKADLSMD
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
NLAGEVKITDEKEKALITKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPIL
HCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NNDDESIKQSRLKLAALTAKTIKQGLDLLGIETLERM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MNIQSLINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKRLGTNPREFAQ
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLDLDGIASKTEIAGPGFINIFLSEEFLAKQAEAALADERLGVALETKQNIVADYS
HHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEECCCCCEECCC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVTRANHIGDWGTQFGMLIANLERIQKEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GEVSMELSDLEGFYRESKKLYDEDEEFAVTARGYVVKLQGGDAFCADMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDNVMGESMYNSMLAPIVADLQEKGLAVESDGAQVVYLDEYKNKDGDP
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRFEELNADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAEQRAIALIEEKNKDLSTEEKAK
CCCCCCHHHEEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IATTVAMAAVKYSDLSKHRTTDYIFDWDNILAFEGNTAPYMQYAYTRVASIFSKADLSMD
HHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
NLAGEVKITDEKEKALITKLMQFEEAVQAVASEGQPHLMCAYLFELAGQFSSFYEACPIL
HCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
NNDDESIKQSRLKLAALTAKTIKQGLDLLGIETLERM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA