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The map label for this gene is serC [H]

Identifier: 209695490

GI number: 209695490

Start: 2187397

End: 2188479

Strand: Direct

Name: serC [H]

Synonym: VSAL_I2041

Alternate gene names: 209695490

Gene position: 2187397-2188479 (Clockwise)

Preceding gene: 209695489

Following gene: 209695494

Centisome position: 65.78

GC content: 39.89

Gene sequence:

>1083_bases
ATGGAAAAAGTATTTAACTTTTGTGCTGGTCCAGCAATGCTGCCAGTAGACGTTCTAGCCCAAGCTCAAAAGGAATTGGT
GAATTGGAACGGTTTAGGGACTTCTGTTATGGAGATCAGCCACCGTAGCAAAGAGTTCATTAAAGTTGCGGAAGAGTCTG
AGCAAGACTTACGTGATTTGTTGGCTATTCCTGATAATTATAAAGTCCTTTTTTGCCAAGGTGGTGCGCGTGCTCAATTT
GCAGCAGTACCACTTAATCTATTAGGTGATAAAACAAAAGCCGATTATGTCGATGCTGGCTATTGGGCACAAAGTGCTGT
CGCGGAAGCGAATAAGTATTGTGAGCCTAATGTCATTGAAGCAATTACCGATTGTGATGGTAAACGCGCTGTTATCCCTG
CATCGCAGTGGCCGTTAAGTGATGATGCTGCTTATGTTCATTTTTGCCCAAATGAAACCATTGATGGTATTGAGATTAAT
GATTTACCAATAACAGATAAGCCAATTGTTGCTGATATGTCGTCGACTATTTTATCTCGTCAAATTGATATTTCTAAATA
CGGTGTTATTTATGCGGGAGCTCAAAAAAATATTGGCCCTGCCGGATTAACGATTGTGATTGTTCGCGATGATCTTTTAG
ATTTAGCGGCACAGTCATTACCAAGCGTATTAAATTATGGTGTTTTAGCAACCCAAGAATCAATGTTTAATACGCCACCA
ACATATGCTTGGTATTTAGCTGGTTTAGTTTTTAAATGGTTAAAATCGAATGGCGGCATTGAAGCGATGGAAGCGCACAA
TCGTAAGAAAGCGGCTGCATTGTATGAGTATATCGACGAATCTGATTTTTATCGCAATGACGTACATACAAATAATCGTT
CGTTAATGAATGTACCCTTTCAATTAGCAAACTCAGACTTGGATGCTCAATTTTTGGCATTAGCAGATGACGCTGGGTTA
AAAGCATTAAAAGGCCATCGAGTCGTCGGTGGTATGCGCGCTTCTATTTATAATGCAATGCCATTAGAAGGTGTTCAGGC
ACTTGTTGATTTTATGAAAGCATTTGAAGCAAAATACGCGTAA

Upstream 100 bases:

>100_bases
CACTTTCTGATTTATTTGTAAGAGAAAAGGTGTTATTAATTTCTATAGAGTGATTTAACAAATCTTATTTAATATTAAAT
AGCAGGAGCCTTTGAGAAAC

Downstream 100 bases:

>100_bases
TTACTGATAAATAAAAAAGCCGATACTGTATTTATAGTATCGGCTTTTTTATTGGTGTTTTGTAAGCGTGCGGGGAACTA
CACCTTGTCTTTTACATTCC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDLLAIPDNYKVLFCQGGARAQF
AAVPLNLLGDKTKADYVDAGYWAQSAVAEANKYCEPNVIEAITDCDGKRAVIPASQWPLSDDAAYVHFCPNETIDGIEIN
DLPITDKPIVADMSSTILSRQIDISKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLAAQSLPSVLNYGVLATQESMFNTPP
TYAWYLAGLVFKWLKSNGGIEAMEAHNRKKAAALYEYIDESDFYRNDVHTNNRSLMNVPFQLANSDLDAQFLALADDAGL
KALKGHRVVGGMRASIYNAMPLEGVQALVDFMKAFEAKYA

Sequences:

>Translated_360_residues
MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDLLAIPDNYKVLFCQGGARAQF
AAVPLNLLGDKTKADYVDAGYWAQSAVAEANKYCEPNVIEAITDCDGKRAVIPASQWPLSDDAAYVHFCPNETIDGIEIN
DLPITDKPIVADMSSTILSRQIDISKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLAAQSLPSVLNYGVLATQESMFNTPP
TYAWYLAGLVFKWLKSNGGIEAMEAHNRKKAAALYEYIDESDFYRNDVHTNNRSLMNVPFQLANSDLDAQFLALADDAGL
KALKGHRVVGGMRASIYNAMPLEGVQALVDFMKAFEAKYA
>Mature_360_residues
MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDLLAIPDNYKVLFCQGGARAQF
AAVPLNLLGDKTKADYVDAGYWAQSAVAEANKYCEPNVIEAITDCDGKRAVIPASQWPLSDDAAYVHFCPNETIDGIEIN
DLPITDKPIVADMSSTILSRQIDISKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLAAQSLPSVLNYGVLATQESMFNTPP
TYAWYLAGLVFKWLKSNGGIEAMEAHNRKKAAALYEYIDESDFYRNDVHTNNRSLMNVPFQLANSDLDAQFLALADDAGL
KALKGHRVVGGMRASIYNAMPLEGVQALVDFMKAFEAKYA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=363, Percent_Identity=48.7603305785124, Blast_Score=340, Evalue=9e-94,
Organism=Homo sapiens, GI10863955, Length=359, Percent_Identity=44.2896935933148, Blast_Score=291, Evalue=8e-79,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=68.5082872928177, Blast_Score=516, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17506897, Length=361, Percent_Identity=43.213296398892, Blast_Score=300, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=42.7461139896373, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21356589, Length=360, Percent_Identity=47.5, Blast_Score=333, Evalue=9e-92,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39459; Mature: 39459

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDL
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIPDNYKVLFCQGGARAQFAAVPLNLLGDKTKADYVDAGYWAQSAVAEANKYCEPNVIE
HCCCCCCEEEEECCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AITDCDGKRAVIPASQWPLSDDAAYVHFCPNETIDGIEINDLPITDKPIVADMSSTILSR
HHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
QIDISKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLAAQSLPSVLNYGVLATQESMFNTPP
HCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHEEHHHHCCCCC
TYAWYLAGLVFKWLKSNGGIEAMEAHNRKKAAALYEYIDESDFYRNDVHTNNRSLMNVPF
HHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
QLANSDLDAQFLALADDAGLKALKGHRVVGGMRASIYNAMPLEGVQALVDFMKAFEAKYA
HHCCCCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDL
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIPDNYKVLFCQGGARAQFAAVPLNLLGDKTKADYVDAGYWAQSAVAEANKYCEPNVIE
HCCCCCCEEEEECCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AITDCDGKRAVIPASQWPLSDDAAYVHFCPNETIDGIEINDLPITDKPIVADMSSTILSR
HHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
QIDISKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLAAQSLPSVLNYGVLATQESMFNTPP
HCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHEEHHHHCCCCC
TYAWYLAGLVFKWLKSNGGIEAMEAHNRKKAAALYEYIDESDFYRNDVHTNNRSLMNVPF
HHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
QLANSDLDAQFLALADDAGLKALKGHRVVGGMRASIYNAMPLEGVQALVDFMKAFEAKYA
HHCCCCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA