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The map label for this gene is nadA [H]

Identifier: 209695368

GI number: 209695368

Start: 2034338

End: 2035387

Strand: Direct

Name: nadA [H]

Synonym: VSAL_I1901

Alternate gene names: 209695368

Gene position: 2034338-2035387 (Clockwise)

Preceding gene: 209695367

Following gene: 209695371

Centisome position: 61.18

GC content: 40.67

Gene sequence:

>1050_bases
ATGGGCCATATTCTAGATCATGTCAACACTGTATATCCTTTCCCTCCAAAACCTACAAAATTAAGTGCTGACGAAAAGAC
TCAGTACATTGCTAAAATCAAACAATTATTAAAAGATAAAAATGCGGTGTTAATTGCCCATTATTATACTGATCCTGAAA
TCCAGGCATTAGCCGAAGAAACAGGCGGCTTTGTTGGTGATTCTTTAGAGATGGCTAAATTTGGTAATCGTCATGATGCA
AAAACATTAGTGATTGCTGGTGTGCGTTTCATGGGAGAATCAGCAAAAATATTAACGCCTGAAAAAACAATCTTAATGCC
AACGTTAGACGCCGAGTGTTCTTTGGATCTTGGTTGTCCTGCAGATAAGTTTACTGAATTTTGTGATGCTCACCCAGATC
ATACCGTTGTTGTGTATGCGAATACCTCAGCAGCCGTTAAAGCCCGTGCTGATTGGGTTGTGACGTCAAGTATTGCATTA
GAAATTGTAGAGCATTTAGATGACGAAGATAAGAAAATTATCTGGGGACCCGATCGCCATTTAGGTTCGTATATTGCGAA
TAAAACAGGCGCAGATATGCTGTTATGGCAGGGCGAATGTATCGTTCATGATGAATTTTCTGCAAAAGCATTAAAAGATG
CGAAAGCACTGCACCCTGATGCCGCGGTTCTTGTTCACCCTGAATCACCTGCAAGTGTGGTTGAATTAGCGGATGCCGTT
GGATCTACAAGCCAATTAATTAAAGCGGCTAAAGAGCTACCACAACAAAAAATGATTGTGGCAACGGATAAAGGCATCTT
CTTTAAGATGCAGCAAATGGTACCAAAAAAAGAATTATTAGAAGCTCCAACAGCAGGTGCGGGTGCAACGTGTCGTAGTT
GTGCACATTGCCCTTGGATGGCGATGAATGGTTTAGTCGCCATTGAAAAAGCATTAAACGAAGGTGGTGCAGGTCATGAG
ATTTTTGTTGATGAAGAGATCCGTATTAAATCACTTATTCCATTAAACCGTATGTTAGATTTTGCTGAGCAGCTAAATGC
CCGTAAATAG

Upstream 100 bases:

>100_bases
AAAAGGAGCTGATTTGCTCCTTTTTTATTTCCCTTAACTTGATGACCCCCTAAGAAGAGGTATAATGTTCAGATTATTTT
AAAAATTAATGAGCTGAGCA

Downstream 100 bases:

>100_bases
TAAATAAGTAGTTGAAATAAACATGGCGACCACACATTGGTCGCCATTTTTTGATCGGTTCTTTTGTAAGCGTGATTAAT
TATTTTTTTTGTCACTTAAA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGHILDHVNTVYPFPPKPTKLSADEKTQYIAKIKQLLKDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHDA
KTLVIAGVRFMGESAKILTPEKTILMPTLDAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPKKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKALNEGGAGHE
IFVDEEIRIKSLIPLNRMLDFAEQLNARK

Sequences:

>Translated_349_residues
MGHILDHVNTVYPFPPKPTKLSADEKTQYIAKIKQLLKDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHDA
KTLVIAGVRFMGESAKILTPEKTILMPTLDAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPKKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKALNEGGAGHE
IFVDEEIRIKSLIPLNRMLDFAEQLNARK
>Mature_348_residues
GHILDHVNTVYPFPPKPTKLSADEKTQYIAKIKQLLKDKNAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHDAK
TLVIAGVRFMGESAKILTPEKTILMPTLDAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALE
IVEHLDDEDKKIIWGPDRHLGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAVG
STSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPKKELLEAPTAGAGATCRSCAHCPWMAMNGLVAIEKALNEGGAGHEI
FVDEEIRIKSLIPLNRMLDFAEQLNARK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=69.9421965317919, Blast_Score=526, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38107; Mature: 37976

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHILDHVNTVYPFPPKPTKLSADEKTQYIAKIKQLLKDKNAVLIAHYYTDPEIQALAEE
CCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHDAKTLVIAGVRFMGESAKILTPEKTILMPTLDAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDDEDKKIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPKKELLEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLVAIEKALNEGGAGHEIFVDEEIRIKSLIPLNRMLDFAEQLNARK
HHCCHHHHHHHHHCCCCCCEEEECCCEEEHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GHILDHVNTVYPFPPKPTKLSADEKTQYIAKIKQLLKDKNAVLIAHYYTDPEIQALAEE
CCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHH
TGGFVGDSLEMAKFGNRHDAKTLVIAGVRFMGESAKILTPEKTILMPTLDAECSLDLGCP
HCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEECCCCEEEEECCCCCCCCCCCCC
ADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDDEDKKIIWGPDRH
HHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCHH
LGSYIANKTGADMLLWQGECIVHDEFSAKALKDAKALHPDAAVLVHPESPASVVELADAV
HHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIKAAKELPQQKMIVATDKGIFFKMQQMVPKKELLEAPTAGAGATCRSCAHCPWM
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHCCCCHH
AMNGLVAIEKALNEGGAGHEIFVDEEIRIKSLIPLNRMLDFAEQLNARK
HHCCHHHHHHHHHCCCCCCEEEECCCEEEHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA