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The map label for this gene is purC

Identifier: 209695191

GI number: 209695191

Start: 1793641

End: 1794744

Strand: Direct

Name: purC

Synonym: VSAL_I1698

Alternate gene names: 209695191

Gene position: 1793641-1794744 (Clockwise)

Preceding gene: 209695186

Following gene: 209695194

Centisome position: 53.94

GC content: 38.77

Gene sequence:

>1104_bases
ATGAGCCTTTCCGAACAAGTACTTGCCGTGAATGATGATTTACCAATCCGTACGGACAAGCCTGTGCATAGCGGTAAAGT
CCGTTCAGTTTATTGGTTAACAGAGGAAGATAGCCGTCGTCTTATCAAAGAGAAAGGCTATAACGTGGCACCTGACGCCC
CTCTTGCTATTATGGTGATCAGTGACCGCATCTCAGCATTTGATTGTATTTGGCACGGTGAAGGCGGACTTAAAGGGATT
CCTGGAAAAGGCGCGGCTCTAAATGCTATCTCGAATCACTGGTTCCAATTATTTAAAGATAATAATTTAGCAGATAGCCA
TATTTTAGATATTCCTCATCCATTTGTTTGGATTGTTCAAAAAGCAAAACCAGTCATGATTGAAGCGATTTGCCGTCAAT
ACATTACGGGTTCAATGTGGCGCGCTTACACCAATGGTGAACGTGAATTCTGTGGTATTCAGATCCCTGAACGCCTAGAA
AAAGACGAAGAACTGGCTGATCTTTTATTAACCCCATCAACAAAAGGCGTTTTAAAAGGCATTGAAGGTGTTTCTGAAGT
TGATGATGTAAACATTACGCGTAAGGACATTGAAAACAATTTTAGTGCTTTCAACTTCTCTTCGATTGAAGATATCGCCT
TATACGAAAAACTGTTAAAAGAAGGTTTTGCGGTTATCTCTAAAGCCTTAAATGACATTGACCAAATTTTTGTTGATACA
AAATTTGAGTTTGGTTATGTTAATGACGCACAAGGCAACGAAAAATTAATTTACATGGATGAAGTTGGTACGCCTGATTC
ATCACGTATTTGGGATAAAAACGCCTACCGTTCTGGTCATATTATTGAAAATTCAAAAGAAGGTTTCCGTCAGTTCTTGT
TGAACCACTTCCCTGAACCTGACATTCTTTTGAATAAGAACCGTATGGATGAGCGCTTTGCGTTAGCAACTGAGAACTCA
TTGCCACTCGAAGCAATGATGGACTTATCAAAAACATACTTAGATATTGCCGCTAAAATTACTGGTGCACCAATTATGTT
AAGTGATAATCCAAAAGCGGAAATAATTAAAGTATTAAAAGAGCAGTATCAACTGGTTGATTAA

Upstream 100 bases:

>100_bases
AACATAAAAAGCAATCGTTTGCTTTTTATACTGGCAGAGATCCAGAGTTCTGGTATGATGCTCTCTGTTTTTACACATAA
GTTTATATAGGAATTCTATA

Downstream 100 bases:

>100_bases
TACCAATAATCGTAACTAACTATTCTATTGATTACTAATAAAAATGGCGACCGCATTGGTCGCCATTTTTGTATCTCTCT
ATTTCAAATAAAAACAAACA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLSEQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGGLKGI
PGKGAALNAISNHWFQLFKDNNLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTNGEREFCGIQIPERLE
KDEELADLLLTPSTKGVLKGIEGVSEVDDVNITRKDIENNFSAFNFSSIEDIALYEKLLKEGFAVISKALNDIDQIFVDT
KFEFGYVNDAQGNEKLIYMDEVGTPDSSRIWDKNAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMDERFALATENS
LPLEAMMDLSKTYLDIAAKITGAPIMLSDNPKAEIIKVLKEQYQLVD

Sequences:

>Translated_367_residues
MSLSEQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGGLKGI
PGKGAALNAISNHWFQLFKDNNLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTNGEREFCGIQIPERLE
KDEELADLLLTPSTKGVLKGIEGVSEVDDVNITRKDIENNFSAFNFSSIEDIALYEKLLKEGFAVISKALNDIDQIFVDT
KFEFGYVNDAQGNEKLIYMDEVGTPDSSRIWDKNAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMDERFALATENS
LPLEAMMDLSKTYLDIAAKITGAPIMLSDNPKAEIIKVLKEQYQLVD
>Mature_366_residues
SLSEQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVISDRISAFDCIWHGEGGLKGIP
GKGAALNAISNHWFQLFKDNNLADSHILDIPHPFVWIVQKAKPVMIEAICRQYITGSMWRAYTNGEREFCGIQIPERLEK
DEELADLLLTPSTKGVLKGIEGVSEVDDVNITRKDIENNFSAFNFSSIEDIALYEKLLKEGFAVISKALNDIDQIFVDTK
FEFGYVNDAQGNEKLIYMDEVGTPDSSRIWDKNAYRSGHIIENSKEGFRQFLLNHFPEPDILLNKNRMDERFALATENSL
PLEAMMDLSKTYLDIAAKITGAPIMLSDNPKAEIIKVLKEQYQLVD

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=295, Percent_Identity=29.1525423728814, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_ALISL (B6EMJ7)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263120.1
- GeneID:   6987308
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1698
- HOGENOM:   HBG555040
- OMA:   SSRIWDG
- ProtClustDB:   PRK13960
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR02735

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 41501; Mature: 41370

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSEQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVI
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWHGEGGLKGIPGKGAALNAISNHWFQLFKDNNLADSHILDIPHPFVWIVQ
ECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEE
KAKPVMIEAICRQYITGSMWRAYTNGEREFCGIQIPERLEKDEELADLLLTPSTKGVLKG
CCCHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCCHHHHCCHHHHHHHHCCCCCHHHHHH
IEGVSEVDDVNITRKDIENNFSAFNFSSIEDIALYEKLLKEGFAVISKALNDIDQIFVDT
HCCCHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVNDAQGNEKLIYMDEVGTPDSSRIWDKNAYRSGHIIENSKEGFRQFLLNHFPEP
CEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCC
DILLNKNRMDERFALATENSLPLEAMMDLSKTYLDIAAKITGAPIMLSDNPKAEIIKVLK
CEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH
EQYQLVD
HHHHCCC
>Mature Secondary Structure 
SLSEQVLAVNDDLPIRTDKPVHSGKVRSVYWLTEEDSRRLIKEKGYNVAPDAPLAIMVI
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIWHGEGGLKGIPGKGAALNAISNHWFQLFKDNNLADSHILDIPHPFVWIVQ
ECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEE
KAKPVMIEAICRQYITGSMWRAYTNGEREFCGIQIPERLEKDEELADLLLTPSTKGVLKG
CCCHHHHHHHHHHHHCCHHHHHHCCCCCEEECCCCHHHHCCHHHHHHHHCCCCCHHHHHH
IEGVSEVDDVNITRKDIENNFSAFNFSSIEDIALYEKLLKEGFAVISKALNDIDQIFVDT
HCCCHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVNDAQGNEKLIYMDEVGTPDSSRIWDKNAYRSGHIIENSKEGFRQFLLNHFPEP
CEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCC
DILLNKNRMDERFALATENSLPLEAMMDLSKTYLDIAAKITGAPIMLSDNPKAEIIKVLK
CEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH
EQYQLVD
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA