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The map label for this gene is fdhB [H]

Identifier: 209694971

GI number: 209694971

Start: 1573197

End: 1573805

Strand: Direct

Name: fdhB [H]

Synonym: VSAL_I1454

Alternate gene names: 209694971

Gene position: 1573197-1573805 (Clockwise)

Preceding gene: 209694970

Following gene: 209694972

Centisome position: 47.31

GC content: 46.47

Gene sequence:

>609_bases
ATGGCTAGAATGAAATTCCTATGCGACACCAAACGTTGTATTGAATGTAACGGCTGTGTCACTGCATGTAAAAACGAAAA
TGATGATGCACTTGAATGGGGCATCCAACGTCGTCGCGTAGTAACACTAAACGACGGTGAACCGGGTGAGACATCAATCT
CTGTCGCTTGTATGCATTGTACAGACGCGCCTTGTATGGCTGTTTGTCCGGCTGATTGTTTTGAGCACACAGAAGATGGC
ATCGTTCGTCACAACAAAGATCTTTGTATCGGTTGTGGTTACTGCCTATTTGCTTGCCCATTTGGTGCGCCGCAGTTCCC
TAAACAGGGTGCGTTTGCTGAGCGTGGCAAAATGGACAAATGTACGTTCTGTGCTGGTGGCCCAGGGGTAGAACCAGGTT
CACAAGAAGAACGTGATAAATACGGCGCAAACCGTATTGCTGAAGGCAAATTACCAATGTGTGCTTCATTATGTTCAACA
AAAGCACTGCTTGCTGGTGATGCAGAGAAAGTCTCTGATATCTTCCGCCAACGTGTTGTAGAACGTGGTGCGAAAGATGC
AGGTTGGACAAATGGTGAAGACTTATCGTTTGATGCGACTAAGAGCTAA

Upstream 100 bases:

>100_bases
CTGCAAACACAGCAACCACCTATGGGTATGATCCTGTGACTCAAATGCAGGAAACGAAAGTAACACTCTGTAATATCACC
AAAGCGTAAGGGGTTATAAA

Downstream 100 bases:

>100_bases
TCCAGTGGAGAGAGTGATGTTGACACAATTAAAACGTCTTTCTCTTTCGTTATTGCTGCCGTTATTGGCAGCATTAACGC
TTTCATTTTCTGTGCCTAGC

Product: formate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MARMKFLCDTKRCIECNGCVTACKNENDDALEWGIQRRRVVTLNDGEPGETSISVACMHCTDAPCMAVCPADCFEHTEDG
IVRHNKDLCIGCGYCLFACPFGAPQFPKQGAFAERGKMDKCTFCAGGPGVEPGSQEERDKYGANRIAEGKLPMCASLCST
KALLAGDAEKVSDIFRQRVVERGAKDAGWTNGEDLSFDATKS

Sequences:

>Translated_202_residues
MARMKFLCDTKRCIECNGCVTACKNENDDALEWGIQRRRVVTLNDGEPGETSISVACMHCTDAPCMAVCPADCFEHTEDG
IVRHNKDLCIGCGYCLFACPFGAPQFPKQGAFAERGKMDKCTFCAGGPGVEPGSQEERDKYGANRIAEGKLPMCASLCST
KALLAGDAEKVSDIFRQRVVERGAKDAGWTNGEDLSFDATKS
>Mature_201_residues
ARMKFLCDTKRCIECNGCVTACKNENDDALEWGIQRRRVVTLNDGEPGETSISVACMHCTDAPCMAVCPADCFEHTEDGI
VRHNKDLCIGCGYCLFACPFGAPQFPKQGAFAERGKMDKCTFCAGGPGVEPGSQEERDKYGANRIAEGKLPMCASLCSTK
ALLAGDAEKVSDIFRQRVVERGAKDAGWTNGEDLSFDATKS

Specific function: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787872, Length=177, Percent_Identity=34.4632768361582, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787122, Length=177, Percent_Identity=32.7683615819209, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789370, Length=208, Percent_Identity=26.4423076923077, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI226510944, Length=182, Percent_Identity=32.967032967033, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790326, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787749, Length=214, Percent_Identity=28.9719626168224, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI2367345, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788811, Length=130, Percent_Identity=32.3076923076923, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789079, Length=101, Percent_Identity=38.6138613861386, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367245, Length=174, Percent_Identity=31.6091954022989, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87082114, Length=91, Percent_Identity=36.2637362637363, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR000813 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 21870; Mature: 21739

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
11.9 %Cys+Met (Translated Protein)
9.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
11.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMKFLCDTKRCIECNGCVTACKNENDDALEWGIQRRRVVTLNDGEPGETSISVACMHC
CCCCCHHHCCCCEEECCCCEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEEEEEC
TDAPCMAVCPADCFEHTEDGIVRHNKDLCIGCGYCLFACPFGAPQFPKQGAFAERGKMDK
CCCCCEEECCHHHHHCCCCCCEECCCCEEEECCHHHHCCCCCCCCCCCCCCCHHCCCCCC
CTFCAGGPGVEPGSQEERDKYGANRIAEGKLPMCASLCSTKALLAGDAEKVSDIFRQRVV
EEEECCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ERGAKDAGWTNGEDLSFDATKS
HCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARMKFLCDTKRCIECNGCVTACKNENDDALEWGIQRRRVVTLNDGEPGETSISVACMHC
CCCCHHHCCCCEEECCCCEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEEEEEC
TDAPCMAVCPADCFEHTEDGIVRHNKDLCIGCGYCLFACPFGAPQFPKQGAFAERGKMDK
CCCCCEEECCHHHHHCCCCCCEECCCCEEEECCHHHHCCCCCCCCCCCCCCCHHCCCCCC
CTFCAGGPGVEPGSQEERDKYGANRIAEGKLPMCASLCSTKALLAGDAEKVSDIFRQRVV
EEEECCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ERGAKDAGWTNGEDLSFDATKS
HCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 4Fe-4S clusters [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1781728; 14500908 [H]