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The map label for this gene is yclF [H]

Identifier: 209694404

GI number: 209694404

Start: 917450

End: 918805

Strand: Reverse

Name: yclF [H]

Synonym: VSAL_I0825

Alternate gene names: 209694404

Gene position: 918805-917450 (Counterclockwise)

Preceding gene: 209694406

Following gene: 209694393

Centisome position: 27.63

GC content: 40.49

Gene sequence:

>1356_bases
ATGCCAAATAACAACAAGTTATTAATGGGACACCCTCAAGGGCTTTTCCTACTTTTTGGAACTGAATTATGGGAACGATT
CTCTTATTACGCCATGAGGGCGATTTTAGTCTTATATTTAACAGATAGAACCATTAATGGTGGTTTAGGCTGGACCGTTA
AGGATGCATTAAGCCTATATGGTACCTATACCGCTCTTATGTATATCACACCACTCATTGGTGGTTGGTTAGCAGATAAT
TATCTTGGCCAACGAAAATCATTACTTATTGGTGGTTTTTTAATGGTCATCGGCCAATTTACGTTGGCTCTTCCTCATAA
TACCTTGCCACTCTCGGTTGAGACTCTCTTTTATGTTGGTTTAGGATTCCTTATTGCTGGTAATGGATTATTCAAACCAA
ATGTATCCACAATGGTGGGTGATTTATACCAAAATGGCGATCATCGTCGTGATGGTGCATTCACGATCTTCTATATGGGG
ATCAATTTAGGCTCATTACTGGCTGGTGTTGTTTCTGGTTCTGTTACTGGAATATGGGGATGGAAAGCCGGCTTTGCTGC
TGCAGGTATTGGTATGATTATTAGCTTAATTATTCAGACCTTTTTTGCACAACGCTTCTTAGGTGATATCGGTGTTCGCC
CTGCTGCACACATTGCAAAAGAAAGAGCAGAAGCAAAAGGAACATCCCATCATGTTTTAAGTAAAGTAGAAACCGATCGT
CTAAAAGTTATTATGGTGATGGGATTGTTCGTTATTGTCTTTTGGGCCGGTTTTGAACAAGCTGGTGGCTTAATGAATAT
ATATTCTCAACAATACACAGATAGAATGATTGGTTCATTTGAAGTCCCTGCGGCTTGGTTTCAATCGTTAAATCCATTCT
TCATCATTACATTAGCCCCACTTATTGCCATCCTATGGATAAAATTAGGTCCTAAAGAGCCAAGCTCACCAATAAAGTTT
GCTCTCGCCTTATTCTTTTTAGCGATTGGTTTTCTTTGCATGGTTGGTGCTGTAATGCAGCAAGGTGGGGACTTAACAAT
CAAAACATCAATGTATTGGTTAGTCGGCGCCTATTTCTTTCATACTTTAGGCGAATTATGTTTATCCCCTATTGGGCTCT
CTTTAGTCACTAAATTAGCACCACTACGCTTAGCCTCTTTAATGATGGGGACATGGTTTGGTTTCAATGCTATCTCAAAT
TACATTGCGGGTGTTGTAGGCTCTCACGTCGAGAGTTTAGGGGCACTAGACATCTTTGCTGGTATCGCAATTTCGGCAAC
TATCTCAGGGATTTTACTATTGATGATTTCAGGAACGTTGATCCGCTGGATGCACGGGGCTGAAAAAGCACACTAG

Upstream 100 bases:

>100_bases
TAGATCACATTTATTCAAACTTTGTTGCAGTAATTACATTGAGAGAGTATAAATTTAACTACTATAAAAAATTAAAATAA
AATTGACTAAAGAGAGCATT

Downstream 100 bases:

>100_bases
TTATATCGTAATACTTATTTAAGTAATAACGACATGGCTAAAACTAAAAAGCCATTTCATCGTATGAAATGGCTTTTTTA
GGTAACTATATTATAACTTA

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGLGWTVKDALSLYGTYTALMYITPLIGGWLADN
YLGQRKSLLIGGFLMVIGQFTLALPHNTLPLSVETLFYVGLGFLIAGNGLFKPNVSTMVGDLYQNGDHRRDGAFTIFYMG
INLGSLLAGVVSGSVTGIWGWKAGFAAAGIGMIISLIIQTFFAQRFLGDIGVRPAAHIAKERAEAKGTSHHVLSKVETDR
LKVIMVMGLFVIVFWAGFEQAGGLMNIYSQQYTDRMIGSFEVPAAWFQSLNPFFIITLAPLIAILWIKLGPKEPSSPIKF
ALALFFLAIGFLCMVGAVMQQGGDLTIKTSMYWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISN
YIAGVVGSHVESLGALDIFAGIAISATISGILLLMISGTLIRWMHGAEKAH

Sequences:

>Translated_451_residues
MPNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGLGWTVKDALSLYGTYTALMYITPLIGGWLADN
YLGQRKSLLIGGFLMVIGQFTLALPHNTLPLSVETLFYVGLGFLIAGNGLFKPNVSTMVGDLYQNGDHRRDGAFTIFYMG
INLGSLLAGVVSGSVTGIWGWKAGFAAAGIGMIISLIIQTFFAQRFLGDIGVRPAAHIAKERAEAKGTSHHVLSKVETDR
LKVIMVMGLFVIVFWAGFEQAGGLMNIYSQQYTDRMIGSFEVPAAWFQSLNPFFIITLAPLIAILWIKLGPKEPSSPIKF
ALALFFLAIGFLCMVGAVMQQGGDLTIKTSMYWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISN
YIAGVVGSHVESLGALDIFAGIAISATISGILLLMISGTLIRWMHGAEKAH
>Mature_450_residues
PNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGLGWTVKDALSLYGTYTALMYITPLIGGWLADNY
LGQRKSLLIGGFLMVIGQFTLALPHNTLPLSVETLFYVGLGFLIAGNGLFKPNVSTMVGDLYQNGDHRRDGAFTIFYMGI
NLGSLLAGVVSGSVTGIWGWKAGFAAAGIGMIISLIIQTFFAQRFLGDIGVRPAAHIAKERAEAKGTSHHVLSKVETDRL
KVIMVMGLFVIVFWAGFEQAGGLMNIYSQQYTDRMIGSFEVPAAWFQSLNPFFIITLAPLIAILWIKLGPKEPSSPIKFA
LALFFLAIGFLCMVGAVMQQGGDLTIKTSMYWLVGAYFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISNY
IAGVVGSHVESLGALDIFAGIAISATISGILLLMISGTLIRWMHGAEKAH

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=388, Percent_Identity=28.6082474226804, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226371746, Length=340, Percent_Identity=25.2941176470588, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226371748, Length=335, Percent_Identity=23.5820895522388, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1787922, Length=482, Percent_Identity=28.6307053941909, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1790572, Length=459, Percent_Identity=27.8867102396514, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789911, Length=441, Percent_Identity=29.2517006802721, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1786927, Length=491, Percent_Identity=27.2912423625255, Blast_Score=170, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71987453, Length=332, Percent_Identity=25.3012048192771, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569141, Length=344, Percent_Identity=25.5813953488372, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571098, Length=331, Percent_Identity=27.7945619335347, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24639583, Length=335, Percent_Identity=30.1492537313433, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571102, Length=331, Percent_Identity=27.7945619335347, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571100, Length=331, Percent_Identity=27.7945619335347, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639585, Length=338, Percent_Identity=29.8816568047337, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639581, Length=323, Percent_Identity=30.3405572755418, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49097; Mature: 48966

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGLGWTVKDALSLY
CCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH
GTYTALMYITPLIGGWLADNYLGQRKSLLIGGFLMVIGQFTLALPHNTLPLSVETLFYVG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LGFLIAGNGLFKPNVSTMVGDLYQNGDHRRDGAFTIFYMGINLGSLLAGVVSGSVTGIWG
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEECC
WKAGFAAAGIGMIISLIIQTFFAQRFLGDIGVRPAAHIAKERAEAKGTSHHVLSKVETDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
LKVIMVMGLFVIVFWAGFEQAGGLMNIYSQQYTDRMIGSFEVPAAWFQSLNPFFIITLAP
HHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEHHHHHH
LIAILWIKLGPKEPSSPIKFALALFFLAIGFLCMVGAVMQQGGDLTIKTSMYWLVGAYFF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
HTLGELCLSPIGLSLVTKLAPLRLASLMMGTWFGFNAISNYIAGVVGSHVESLGALDIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAISATISGILLLMISGTLIRWMHGAEKAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PNNNKLLMGHPQGLFLLFGTELWERFSYYAMRAILVLYLTDRTINGGLGWTVKDALSLY
CCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]