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The map label for this gene is dcuB [H]

Identifier: 209694272

GI number: 209694272

Start: 767012

End: 768346

Strand: Reverse

Name: dcuB [H]

Synonym: VSAL_I0683

Alternate gene names: 209694272

Gene position: 768346-767012 (Counterclockwise)

Preceding gene: 209694273

Following gene: 209694267

Centisome position: 23.11

GC content: 42.17

Gene sequence:

>1335_bases
ATGAATATTGATTTTTGGCTACAGCTTGCTGTAGTTTTAGGCTGTATCGGTATTGGCGGACGATTTGGCGGAGTTGGATT
AGGTGCCGCTGGTGGTTTAGGTGTCTGTTTATTAGTCTTAGGTTTTGGTCTACAGCCTGCATCTCCTCCAGTAACGGTAC
TACTAATCATTATCGCTGTAATCGCTTGTACCAGCGTACTACAAGGCGCTGGCGGTCTCGATTTTTTAGTTCGTATCGCT
GAAAAACTTCTTCGTAAGAAGCCGAGTGCTATTACATTTCTCGGCCCTTTAATTTCCTCAATGTTTGTTATTTTTTGTGG
TACATCTTATGTAGCATTCGCAGTTTATCCAGTTATTGCCGAAGTTGCTGCTGAAGCAAAAATCCGCCCAGAGCGTCCTA
TGTCAATGGCTGTTATAGCTTCAGGTATTGCGATTACAGCAAGCCCAATGAGTGCTGCAACAGCAGGTATGATCGCCTCA
CTTTCTCTTTATGACGTATCCTTCTTCCAAATCCTTGCCGTTAGTATGCCTGCATTTTTAATTGGGGCATTATGCGGCTG
TGCATTCGTATACAAGCGTGGTTTAGAACTTGAGCAAGATCCTGAATTTCAGCGTCGCGTCGCATCAGGTGAATATCAAC
TTATTCATGAAGATGTCAATTCACCAGAAGAAGAATACAAACCGTCAACAGGGGTTAAGGCAAGCGTACTTGTGTTCGGA
TTAGGTGTTGCTACTGTTATTTTATTTGGTACTTTTAAGAGCCTACTACCATCTTGGGATATTGACGGTAAAACGGTTGT
ACTATCTACACCGATGCTAATCCAAATGGTGATGTTAGCCAGTGCATTATTTATCATCGTGTTTGCCAAAGTACCAAGTG
ACAAGTTTGCATCAGGATCAGTATTCCGTTCTGGTCTTATTGGTGTCGTGGGTGTATTCGGTATTTCTTGGATGACAGGA
ACGTTCTTCAATGCTTACCAGCCATTCTTTGAAACAACCTTTGAAGGTATGGTAGAAACAGCACCAATGATGTTCGGTTT
GATTTTGTTCTGTTTTTCTGCGGTTATCTTTAGCCCATCAGCAACTGTTTCTGCATTAATGCCCCTTGGCGCAGCAATGG
GGATCCCTCCTGGTTTACTCGTTGCACTATACCCTGCAACCTGTGGAGATTTCATAGTTCCAGGTACAGGTCAAATTGGT
TGTTTATCTTTTGACCGTACAGGCACAACCCGATTAGGCACTTATGTTATAAACCATAGTTACATACTTCCTGGTTTTGT
CATGGTTATTTCATCGGTAACTGCTGGTTACTTCATTTCAAAAATTGTTTTTTAA

Upstream 100 bases:

>100_bases
AATTAGAACAACACAGGCTACTCGCTGGAATTCGGCTAGTAGCCTCCCTTCTTATTTTTAATTATTAACAACTACTTAAC
CGTATGATAGGTATTTCTTT

Downstream 100 bases:

>100_bases
CGTTTGCACTCTTTGCTAGAATCGATACGTTATTAATAAATGCATCGCTATATAAAATAGACTACCAACTAAAATTGGTG
GTCTATTTTTAGATGGACTC

Product: anaerobic c4-dicarboxylate transporter DcuB

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNIDFWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAVIACTSVLQGAGGLDFLVRIA
EKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIAEVAAEAKIRPERPMSMAVIASGIAITASPMSAATAGMIAS
LSLYDVSFFQILAVSMPAFLIGALCGCAFVYKRGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFG
LGVATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGSVFRSGLIGVVGVFGISWMTG
TFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPSATVSALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQIG
CLSFDRTGTTRLGTYVINHSYILPGFVMVISSVTAGYFISKIVF

Sequences:

>Translated_444_residues
MNIDFWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAVIACTSVLQGAGGLDFLVRIA
EKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIAEVAAEAKIRPERPMSMAVIASGIAITASPMSAATAGMIAS
LSLYDVSFFQILAVSMPAFLIGALCGCAFVYKRGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFG
LGVATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGSVFRSGLIGVVGVFGISWMTG
TFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPSATVSALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQIG
CLSFDRTGTTRLGTYVINHSYILPGFVMVISSVTAGYFISKIVF
>Mature_444_residues
MNIDFWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAVIACTSVLQGAGGLDFLVRIA
EKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIAEVAAEAKIRPERPMSMAVIASGIAITASPMSAATAGMIAS
LSLYDVSFFQILAVSMPAFLIGALCGCAFVYKRGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFG
LGVATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGSVFRSGLIGVVGVFGISWMTG
TFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPSATVSALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQIG
CLSFDRTGTTRLGTYVINHSYILPGFVMVISSVTAGYFISKIVF

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=403, Percent_Identity=35.2357320099256, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790580, Length=433, Percent_Identity=36.0277136258661, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46746; Mature: 46746

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDFWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAV
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IACTSVLQGAGGLDFLVRIAEKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIA
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVAAEAKIRPERPMSMAVIASGIAITASPMSAATAGMIASLSLYDVSFFQILAVSMPAFL
HHHHHCCCCCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGALCGCAFVYKRGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFG
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEHHHCCCCHHHCCCCCCCCHHHHHHH
LGVATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGS
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VFRSGLIGVVGVFGISWMTGTFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATVSALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQIGCLSFDRTGTTRLGTYVINHS
HHHHHHHHHHHHHCCCCHHHHEEECCCCCCEEECCCCCEEEEEECCCCCCCHHEEEECCC
YILPGFVMVISSVTAGYFISKIVF
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIDFWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAV
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IACTSVLQGAGGLDFLVRIAEKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIA
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVAAEAKIRPERPMSMAVIASGIAITASPMSAATAGMIASLSLYDVSFFQILAVSMPAFL
HHHHHCCCCCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGALCGCAFVYKRGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFG
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEHHHCCCCHHHCCCCCCCCHHHHHHH
LGVATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGS
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VFRSGLIGVVGVFGISWMTGTFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATVSALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQIGCLSFDRTGTTRLGTYVINHS
HHHHHHHHHHHHHCCCCHHHHEEECCCCCCEEECCCCCEEEEEECCCCCCCHHEEEECCC
YILPGFVMVISSVTAGYFISKIVF
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]