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The map label for this gene is luxS

Identifier: 209694236

GI number: 209694236

Start: 718309

End: 718827

Strand: Direct

Name: luxS

Synonym: VSAL_I0645

Alternate gene names: 209694236

Gene position: 718309-718827 (Clockwise)

Preceding gene: 209694235

Following gene: 209694239

Centisome position: 21.6

GC content: 36.42

Gene sequence:

>519_bases
ATGCCATTATTAGACAGTTTTACTGTAGATCATACCCGTATGGAAGCACCCGCGGTACGTGTTGCAAAGAAAATGCAAAC
GCCTAAAGGTGATACTATCACCGTATTTGATTTACGCTTTACTGCACCAAATAAAGATATTTTATCTGAAAAAGGTATTC
ACACATTAGAGCATCTATATGCAGGGTTCATGCGTAATCATTTGAATGGTACGGATGTAGAAATTATTGATATTTCACCA
ATGGGATGTCGTACTGGTTTTTACATGAGCTTAATTGGTACACCTGTAGAACAAACGGTTGCTAACGCTTGGATTGCATC
AATGGAAGATGTTCTTAATGTTGAAGACCAGAATAAAATACCTGAATTAAATGAATATCAATGTGGTACATATACCATGC
ATTCTTTAGAAGAAGCGAAAGCGATTGCTACCGCTATTTTAGCCGCAGGTATTCAAGTAAATAAAAATGATGACTTGGCT
CTTCCTGAGTCAATGCTTAAAGAACTATCTGTAGATTAA

Upstream 100 bases:

>100_bases
AACGTATGGTTGGCAATTAAAACAATGTAAAGTTGAGCTTGAAAGACAAAGTAGTTGGTGGTGGTAAGTCACCGCTATCC
ATAAATTAAAGGAATAAATT

Downstream 100 bases:

>100_bases
TTTCATTTCGAATTTAAAAAGCCCGCATTAGAAATCTAATACGGGCTTTTTTGTGCTTGTATATAAGCTAATTATTATCG
CTACTAGGGAATACTTTAAC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPLLDSFTVDHTRMEAPAVRVAKKMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGTDVEIIDISP
MGCRTGFYMSLIGTPVEQTVANAWIASMEDVLNVEDQNKIPELNEYQCGTYTMHSLEEAKAIATAILAAGIQVNKNDDLA
LPESMLKELSVD

Sequences:

>Translated_172_residues
MPLLDSFTVDHTRMEAPAVRVAKKMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGTDVEIIDISP
MGCRTGFYMSLIGTPVEQTVANAWIASMEDVLNVEDQNKIPELNEYQCGTYTMHSLEEAKAIATAILAAGIQVNKNDDLA
LPESMLKELSVD
>Mature_171_residues
PLLDSFTVDHTRMEAPAVRVAKKMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGTDVEIIDISPM
GCRTGFYMSLIGTPVEQTVANAWIASMEDVLNVEDQNKIPELNEYQCGTYTMHSLEEAKAIATAILAAGIQVNKNDDLAL
PESMLKELSVD

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=74.2690058479532, Blast_Score=278, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_ALISL (B6EGB5)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262164.1
- GeneID:   6986582
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0645
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 19055; Mature: 18924

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMEAPAVRVAKKMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRNHLNGTDVEIIDISPMGCRTGFYMSLIGTPVEQTVANAWIASMEDVLNVEDQNKI
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PELNEYQCGTYTMHSLEEAKAIATAILAAGIQVNKNDDLALPESMLKELSVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMEAPAVRVAKKMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLY
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRNHLNGTDVEIIDISPMGCRTGFYMSLIGTPVEQTVANAWIASMEDVLNVEDQNKI
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
PELNEYQCGTYTMHSLEEAKAIATAILAAGIQVNKNDDLALPESMLKELSVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA