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The map label for this gene is tktA [H]

Identifier: 209694147

GI number: 209694147

Start: 605768

End: 607765

Strand: Direct

Name: tktA [H]

Synonym: VSAL_I0554

Alternate gene names: 209694147

Gene position: 605768-607765 (Clockwise)

Preceding gene: 209694138

Following gene: 209694148

Centisome position: 18.22

GC content: 46.05

Gene sequence:

>1998_bases
ATGTCTTCACGTAAACATTTAGCAAATGCAATCCGCGCTTTAAGCATGGACGGTGTACAACAAGCAAATTCTGGTCACCC
AGGAGCACCAATGGGCATGGCAGACATCGCTGAAGTATTATGGCGTAGTCACCTAAATCACAACCCACAGAATCCAGAGT
GGGCTGATCGCGACCGTTTCATTCTTTCTAACGGCCACGGCTCTATGCTGATTTATTCTCTGCTTCATCTTTCAGGTTAT
AACCTGTCTATCGAAGACTTAAAGAACTTCCGTCAATTGCATTCTAAAACTCCGGGTCACCCTGAGTACGGCTATGCACC
AGGTATTGAAACAACAACGGGTCCATTAGGCCAAGGCATCACTAATGGCGTTGGTATGGCAATGGCTGAAAAAGCATTGG
CAGCACAATTTAACCGTGAAGGCCACGACATCGTTGACCATAATACGTATGTGTTCATGGGCGATGGTTGTTTAATGGAA
GGTATTTCTCACGAAGCGTGTTCACTTGCTGGCACACTAGGCCTAGGCAAACTGGTTGCTTTCTGGGATGACAACGGTAT
TTCTATCGATGGTGAAGTGGAAGGTTGGTTCTCTGACGATACCCCTAAACGTTTTGAAGCGTACGGCTGGCATGTAATTC
CTGCGGTTGATGGTCACGATGCTGACGCAATCAATGCGGCGATTGAAGCGGCAAAAGCAGAAACAGGTCGTCCTACTTTG
ATTTGTACTAAAACTATCATCGGTTTTGGTTCTCCAAATAAAGAAGGTACGCACGACTGTCACGGTGCTCCACTAGGTGC
TGATGAGATTGTTGCGACTAAAGCGAAACTTGGTTGGGAGTTTGGTCCTTTTGACATTCCTACTGATGTATATGCTGAGT
GGAACGCAAAAGAAGCAGGCAAAGCAAAAGAAGCGTCTTGGAATGCTAAATTTGATGCCTACGCTGCTGCACACCCTGAA
CTAGCTGCTGAATATAAGCGTCGTGTCAACGGTGGTTTACCTGCTGAGTGGGAAGAAAAAACATCGGCAATCATTGCTGA
TCTTCAAGCTAATCCTGCAAACATCGCATCACGTAAAGCATCGCAAAATGCACTAGAAGCGTTTGGTGCAATGTTACCTG
AATTCATGGGCGGCTCTGCTGACCTTGCACCGTCTAACTTGACGATGTGGTCTGGCTCTAAATCATTAACCGCTGATGAT
TTCTCTGGTAACTACATTCACTACGGTGTACGTGAATTTGCGATGACAGCAATCATGAACGGTATCGCTCTGCACGGTGG
TTTCGTACCCTATGGCGCAACGTTCCTAATGTTCATGGAATACGCGCGTAACGCAATGCGTATGGCTGCACTGATGAAAA
TTCAGAACATCCAAGTGTACACTCACGATTCAATCGGTCTAGGTGAAGATGGTCCAACTCACCAACCTGTTGAGCAAATC
GCTTCACTGCGTTTAACTCCGAACATGAGCACATGGCGCCCATGTGACCAAGTTGAATCTGCGGTTGCTTGGAAACTCGC
GATTGAACGTCGTGATGGTCCTACGGCTCTGATCTTCTCTCGTCAAAACCTTGCACAACAAGATCGTGATGCAGAGCAAG
TCGCTAATATAGCAAAGGGTGGTTACATCCTGAAAGATTGTGAAGGTCAACCTGAGCTTATCTTTATCGCTACTGGTTCA
GAAGTTGAACTTGCAGTTGAAGCTGCGGCTCAACTTACAGCGGAAGGGAAAGCGGTACGTGTTGTATCAATGCCAGCAAC
AGATGCATTTGATAAGCAAGATGAAGCCTACCGTGAATCAGTACTTCCATCAGCAGTAACAAAACGTGTTGCTATTGAAG
CGGGTATTGCTGACTTCTGGTATAAGTATGTTGGTTTCGGTGGCAAGATCATCGGTATGACAACGTTTGGTGAATCAGCG
CCTGCTGACGAGCTATTCAAAATGTTTGGTTTCACTACTGAAAATGCAGTGAAAACAGCAAAAGAGCTTTTAGCTTAA

Upstream 100 bases:

>100_bases
TACGGCGCTGCAAATTTAAGTTAATCCATAAATATGGGTAACTAATCAAGAGTTAACTAGCTCAATAAATATATAGTCCT
TCGAATTCTCAGGAGCAGGC

Downstream 100 bases:

>100_bases
TCAAGAGTTATTCGCTTAATAAAAGCGAGTAATTGAATAAAAAGCGAAGTTATCGAAAGGTGGCTTCGCTTTTTTGATCC
TTTAAGAAAAAAGTGAAAAG

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGY
NLSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLME
GISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTL
ICTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAGKAKEASWNAKFDAYAAAHPE
LAAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADD
FSGNYIHYGVREFAMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQI
ASLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGQPELIFIATGS
EVELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRESVLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESA
PADELFKMFGFTTENAVKTAKELLA

Sequences:

>Translated_665_residues
MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGY
NLSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLME
GISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTL
ICTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAGKAKEASWNAKFDAYAAAHPE
LAAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADD
FSGNYIHYGVREFAMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQI
ASLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGQPELIFIATGS
EVELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRESVLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESA
PADELFKMFGFTTENAVKTAKELLA
>Mature_664_residues
SSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGYN
LSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLMEG
ISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTLI
CTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAGKAKEASWNAKFDAYAAAHPEL
AAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADDF
SGNYIHYGVREFAMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQIA
SLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGQPELIFIATGSE
VELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRESVLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESAP
ADELFKMFGFTTENAVKTAKELLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=685, Percent_Identity=26.7153284671533, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI4507521, Length=685, Percent_Identity=26.7153284671533, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI133778974, Length=681, Percent_Identity=25.697503671072, Blast_Score=142, Evalue=9e-34,
Organism=Escherichia coli, GI48994911, Length=664, Percent_Identity=75.9036144578313, Blast_Score=1080, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=662, Percent_Identity=69.9395770392749, Blast_Score=991, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=680, Percent_Identity=24.8529411764706, Blast_Score=158, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=673, Percent_Identity=48.8855869242199, Blast_Score=601, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=44.8736998514116, Blast_Score=555, Evalue=1e-159,
Organism=Drosophila melanogaster, GI45551847, Length=683, Percent_Identity=26.6471449487555, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI45550715, Length=683, Percent_Identity=26.6471449487555, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24645119, Length=649, Percent_Identity=26.1941448382126, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24666278, Length=673, Percent_Identity=24.0713224368499, Blast_Score=145, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71862; Mature: 71730

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
ILSNGHGSMLIYSLLHLSGYNLSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
TNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLMEGISHEACSLAGTLGLGKLVA
HCCHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCHHHHCCCHHHHHHHHHCCCCCEEE
FWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTL
EECCCCEEECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
ICTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAG
EEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHCC
KAKEASWNAKFDAYAAAHPELAAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKA
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCCHHHHHHHH
SQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADDFSGNYIHYGVREFAMTAIMN
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
GIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHH
ASLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKG
HHEECCCCCCCCCCHHHHHHHHEEEEEEECCCCCEEEEEECHHHHHHCCCHHHHHHHHCC
GYILKDCEGQPELIFIATGSEVELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRES
CEEEECCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
VLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESAPADELFKMFGFTTENAVKTA
HCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHH
KELLA
HHHHC
>Mature Secondary Structure 
SSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
ILSNGHGSMLIYSLLHLSGYNLSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
TNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLMEGISHEACSLAGTLGLGKLVA
HCCHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCHHHHCCCHHHHHHHHHCCCCCEEE
FWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTL
EECCCCEEECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
ICTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAG
EEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHCC
KAKEASWNAKFDAYAAAHPELAAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKA
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCCHHHHHHHH
SQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADDFSGNYIHYGVREFAMTAIMN
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
GIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHH
ASLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKG
HHEECCCCCCCCCCHHHHHHHHEEEEEEECCCCCEEEEEECHHHHHHCCCHHHHHHHHCC
GYILKDCEGQPELIFIATGSEVELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRES
CEEEECCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
VLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESAPADELFKMFGFTTENAVKTA
HCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHH
KELLA
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA