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The map label for this gene is argI [H]

Identifier: 209694113

GI number: 209694113

Start: 574311

End: 575315

Strand: Reverse

Name: argI [H]

Synonym: VSAL_I0520

Alternate gene names: 209694113

Gene position: 575315-574311 (Counterclockwise)

Preceding gene: 209694114

Following gene: 209694112

Centisome position: 17.3

GC content: 40.5

Gene sequence:

>1005_bases
ATGGCTTTTAATTTACGTAATAGAAATTTTCTTAAACTGTTGGATTTCACACCTAAAGAAATTCAGCATTTACTCGATTT
ATCTGCTGATTTAAAAAAAGCAAAATACGCAGGTTATGAACAACCGCGTTTATCGGGTAAAAATATTGCGCTTATTTTTG
AAAAGTCATCCACTCGAACTCGATGCGCTTTTGAAGTCGCGGCCTTTGATCAAGGAGCTAAAGTCACTTATCTTGGGCCT
TCTGGATCTCAAATTGGTCACAAAGAATCAATAAAAGATACGGCTCGTGTATTGGGCCGTATGTATGATGGCATTGAATA
TCGTGGCTTTGGGCAATCGATTGTTGAAGAGCTTGGTAAATACGCAGGGGTTCCAGTATGGAATGGGCTCACTGATGAAT
TTCATCCAACTCAAATTCTCGCTGATTTCCTTACTATGCAAGAATACGCAGAAGATAAGCAATTAAATCAAATCAAATTT
GCCTACCTTGGGGATGCCCGCAATAACATGGGTAACTCACTAATGGTAGGGGCAGCGAAAATGGGCATGGAGATCCGTCT
CGTTGCACCAAAACAATTTTGGCCAGAAGATACGCTAGTAACACAATGCCAAGAAATTGCGAGTCAAACAGGCGCTAAAA
TCATTCTAACCGAAGACGTAACAACGGGTGTTGAAGGGTGTGATTTTTTATATACCGATGTTTGGGTTTCTATGGGCGAA
GCCCCTGAAGCTTGGGATGAACGTGTCGCTCTGATGACGCCATATCAAATCAATATGAACGTAATAAAAGCCACTAATAA
CCCCAATGTTAAATTCATGCATTGTTTACCTGCCTTCCATAATGATGAAACCGCTCTAGGTAAAGAGATAGCAGAAAAAT
ACGGGATGAATGGGTTAGAAGTGACCGATGAAGTTTTTGAATCGGATTACTCCATTGTATTTGATGAAGCCGAAAATCGC
ATGCACACAATAAAAGCCATAATGGTCGCAACTCTAGGCCAGTAA

Upstream 100 bases:

>100_bases
TTTAATAAAACCCACAAAACAATAAAATATATATTCACATTTAATGCATTTATATGTTTAAATGAATTTTCAGATTTGGC
ACAACACCAAGGAGCATGGT

Downstream 100 bases:

>100_bases
ATCTAAGATACCGAATAAGAACAAGAATAATCAAAAGAAGTTTGATGCAAACGCTTGCTTAGGATTTTGATACGAGTATA
ATTTCGCGCAATTTACTAGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAFNLRNRNFLKLLDFTPKEIQHLLDLSADLKKAKYAGYEQPRLSGKNIALIFEKSSTRTRCAFEVAAFDQGAKVTYLGP
SGSQIGHKESIKDTARVLGRMYDGIEYRGFGQSIVEELGKYAGVPVWNGLTDEFHPTQILADFLTMQEYAEDKQLNQIKF
AYLGDARNNMGNSLMVGAAKMGMEIRLVAPKQFWPEDTLVTQCQEIASQTGAKIILTEDVTTGVEGCDFLYTDVWVSMGE
APEAWDERVALMTPYQINMNVIKATNNPNVKFMHCLPAFHNDETALGKEIAEKYGMNGLEVTDEVFESDYSIVFDEAENR
MHTIKAIMVATLGQ

Sequences:

>Translated_334_residues
MAFNLRNRNFLKLLDFTPKEIQHLLDLSADLKKAKYAGYEQPRLSGKNIALIFEKSSTRTRCAFEVAAFDQGAKVTYLGP
SGSQIGHKESIKDTARVLGRMYDGIEYRGFGQSIVEELGKYAGVPVWNGLTDEFHPTQILADFLTMQEYAEDKQLNQIKF
AYLGDARNNMGNSLMVGAAKMGMEIRLVAPKQFWPEDTLVTQCQEIASQTGAKIILTEDVTTGVEGCDFLYTDVWVSMGE
APEAWDERVALMTPYQINMNVIKATNNPNVKFMHCLPAFHNDETALGKEIAEKYGMNGLEVTDEVFESDYSIVFDEAENR
MHTIKAIMVATLGQ
>Mature_333_residues
AFNLRNRNFLKLLDFTPKEIQHLLDLSADLKKAKYAGYEQPRLSGKNIALIFEKSSTRTRCAFEVAAFDQGAKVTYLGPS
GSQIGHKESIKDTARVLGRMYDGIEYRGFGQSIVEELGKYAGVPVWNGLTDEFHPTQILADFLTMQEYAEDKQLNQIKFA
YLGDARNNMGNSLMVGAAKMGMEIRLVAPKQFWPEDTLVTQCQEIASQTGAKIILTEDVTTGVEGCDFLYTDVWVSMGEA
PEAWDERVALMTPYQINMNVIKATNNPNVKFMHCLPAFHNDETALGKEIAEKYGMNGLEVTDEVFESDYSIVFDEAENRM
HTIKAIMVATLGQ

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=329, Percent_Identity=38.6018237082067, Blast_Score=214, Evalue=9e-56,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=67.7811550151976, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=66.2650602409639, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI48994908, Length=374, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=32.3170731707317, Blast_Score=155, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322331, Length=276, Percent_Identity=27.1739130434783, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37432; Mature: 37301

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNLRNRNFLKLLDFTPKEIQHLLDLSADLKKAKYAGYEQPRLSGKNIALIFEKSSTRT
CEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC
RCAFEVAAFDQGAKVTYLGPSGSQIGHKESIKDTARVLGRMYDGIEYRGFGQSIVEELGK
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFLTMQEYAEDKQLNQIKFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEHHH
MGMEIRLVAPKQFWPEDTLVTQCQEIASQTGAKIILTEDVTTGVEGCDFLYTDVWVSMGE
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
APEAWDERVALMTPYQINMNVIKATNNPNVKFMHCLPAFHNDETALGKEIAEKYGMNGLE
CCCHHHCCEEEECCEEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
VTDEVFESDYSIVFDEAENRMHTIKAIMVATLGQ
CCHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFNLRNRNFLKLLDFTPKEIQHLLDLSADLKKAKYAGYEQPRLSGKNIALIFEKSSTRT
EECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC
RCAFEVAAFDQGAKVTYLGPSGSQIGHKESIKDTARVLGRMYDGIEYRGFGQSIVEELGK
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFLTMQEYAEDKQLNQIKFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEHHH
MGMEIRLVAPKQFWPEDTLVTQCQEIASQTGAKIILTEDVTTGVEGCDFLYTDVWVSMGE
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
APEAWDERVALMTPYQINMNVIKATNNPNVKFMHCLPAFHNDETALGKEIAEKYGMNGLE
CCCHHHCCEEEECCEEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
VTDEVFESDYSIVFDEAENRMHTIKAIMVATLGQ
CCHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA