Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 209694107

GI number: 209694107

Start: 568435

End: 569160

Strand: Direct

Name: plsC [H]

Synonym: VSAL_I0512

Alternate gene names: 209694107

Gene position: 568435-569160 (Clockwise)

Preceding gene: 209694106

Following gene: 209694115

Centisome position: 17.09

GC content: 40.5

Gene sequence:

>726_bases
ATGATTGCATTGTTACGCCTGATTGCTTTGGCTATCTTTGCTGTCTTTACGTTTGTATTTGGCTGTGGTTATTGCTTATT
AAGCCCACGTAACCCAAAACACGTTTATACTTTTGGTCTTTGGTTTGCTCGTATGTCGCGAGTATTTGGTATTAAACTTG
AAGTGCGAGTTCCTGAAAGTGTTAAAAATTCAGGACCAAGTTTATACATCGCAAACCATCAAAATAGCTGGGATTTGTTT
ACTGTCTCTGGGGCAATTCAACCAAGAACAGTGACTGTAGGTAAAAAAAGCATCGCGTGGATGCCGTTGTTTGGTCAACT
GTATTGGATCACCGGTAATATTCTTATTGACCGTAATAATCGCAGTAAAGCGGTAGGTACGATTTCACAAGTTGCGGATA
ATATTAAGAAACGTAATGTCTCTGTATGGATGTTCCCAGAAGGAACGCGTTCTCGTGGTCGTGGTTTATTGCCATTTAAA
ACGGGTGCATTTCATGCGGCTATCGCTGCTGATGTTCCAGTGACTCCGATTGTGTGTAGTAATACGGAAGGCGTAAAACT
AAATCGTTGGAATAACGGTGTGGTTATTGTCGAAATTTTACCGCCAGTAAGCCTTGATGGTTACACGAAAGCGAACGTTC
GTGAATTAGCGAATGAATGTCGTGAACAAATGAAAGTTAAGCTAGAAGAATTAAATAAAGAAGTTGCAGAACGCAACCAA
GCTTAA

Upstream 100 bases:

>100_bases
GTGGAAACCGGGTATATATGACCCGGTTTTTTATTGTTTGTAATATAAGTACACTGAATTAGATATTGAGTGGAATGTAT
ATATTTTAGGAGAAACACTT

Downstream 100 bases:

>100_bases
ATTTTATAATTATTTTTAAGGGTATACGGATCTCCGTGTACCCTTTTTATTTTGATGTGTAGAAGAAATAATGAAAGAAG
AAGTTGTCCTTGTTAATGCG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIALLRLIALAIFAVFTFVFGCGYCLLSPRNPKHVYTFGLWFARMSRVFGIKLEVRVPESVKNSGPSLYIANHQNSWDLF
TVSGAIQPRTVTVGKKSIAWMPLFGQLYWITGNILIDRNNRSKAVGTISQVADNIKKRNVSVWMFPEGTRSRGRGLLPFK
TGAFHAAIAADVPVTPIVCSNTEGVKLNRWNNGVVIVEILPPVSLDGYTKANVRELANECREQMKVKLEELNKEVAERNQ
A

Sequences:

>Translated_241_residues
MIALLRLIALAIFAVFTFVFGCGYCLLSPRNPKHVYTFGLWFARMSRVFGIKLEVRVPESVKNSGPSLYIANHQNSWDLF
TVSGAIQPRTVTVGKKSIAWMPLFGQLYWITGNILIDRNNRSKAVGTISQVADNIKKRNVSVWMFPEGTRSRGRGLLPFK
TGAFHAAIAADVPVTPIVCSNTEGVKLNRWNNGVVIVEILPPVSLDGYTKANVRELANECREQMKVKLEELNKEVAERNQ
A
>Mature_241_residues
MIALLRLIALAIFAVFTFVFGCGYCLLSPRNPKHVYTFGLWFARMSRVFGIKLEVRVPESVKNSGPSLYIANHQNSWDLF
TVSGAIQPRTVTVGKKSIAWMPLFGQLYWITGNILIDRNNRSKAVGTISQVADNIKKRNVSVWMFPEGTRSRGRGLLPFK
TGAFHAAIAADVPVTPIVCSNTEGVKLNRWNNGVVIVEILPPVSLDGYTKANVRELANECREQMKVKLEELNKEVAERNQ
A

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=223, Percent_Identity=33.6322869955157, Blast_Score=140, Evalue=9e-34,
Organism=Homo sapiens, GI15100175, Length=223, Percent_Identity=33.6322869955157, Blast_Score=140, Evalue=9e-34,
Organism=Homo sapiens, GI6041665, Length=201, Percent_Identity=29.8507462686567, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1789395, Length=242, Percent_Identity=59.504132231405, Blast_Score=311, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI17564032, Length=194, Percent_Identity=34.020618556701, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17568319, Length=215, Percent_Identity=32.093023255814, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320151, Length=225, Percent_Identity=32.8888888888889, Blast_Score=132, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281364648, Length=237, Percent_Identity=31.6455696202532, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582856, Length=237, Percent_Identity=31.6455696202532, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582854, Length=237, Percent_Identity=31.6455696202532, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24641614, Length=221, Percent_Identity=33.0316742081448, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641612, Length=221, Percent_Identity=33.0316742081448, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26908; Mature: 26908

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLRLIALAIFAVFTFVFGCGYCLLSPRNPKHVYTFGLWFARMSRVFGIKLEVRVPES
CHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEHHHHHHHHHHHHEEEEEEECCHH
VKNSGPSLYIANHQNSWDLFTVSGAIQPRTVTVGKKSIAWMPLFGQLYWITGNILIDRNN
HHCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEECCCEEEEEEEEEEEECCC
RSKAVGTISQVADNIKKRNVSVWMFPEGTRSRGRGLLPFKTGAFHAAIAADVPVTPIVCS
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEC
NTEGVKLNRWNNGVVIVEILPPVSLDGYTKANVRELANECREQMKVKLEELNKEVAERNQ
CCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MIALLRLIALAIFAVFTFVFGCGYCLLSPRNPKHVYTFGLWFARMSRVFGIKLEVRVPES
CHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEHHHHHHHHHHHHEEEEEEECCHH
VKNSGPSLYIANHQNSWDLFTVSGAIQPRTVTVGKKSIAWMPLFGQLYWITGNILIDRNN
HHCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEECCCEEEEEEEEEEEECCC
RSKAVGTISQVADNIKKRNVSVWMFPEGTRSRGRGLLPFKTGAFHAAIAADVPVTPIVCS
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEC
NTEGVKLNRWNNGVVIVEILPPVSLDGYTKANVRELANECREQMKVKLEELNKEVAERNQ
CCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]