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The map label for this gene is murA

Identifier: 209694106

GI number: 209694106

Start: 567032

End: 568300

Strand: Direct

Name: murA

Synonym: VSAL_I0511

Alternate gene names: 209694106

Gene position: 567032-568300 (Clockwise)

Preceding gene: 209694105

Following gene: 209694107

Centisome position: 17.05

GC content: 43.03

Gene sequence:

>1269_bases
ATGTATAAGTTCCGAATTCAAGGAAGCGATAAACCACTTTCAGGAGAGGTTACGATTTCTGGTGCAAAAAATGCTGCACT
ACCAATTTTATTCGCTGCATTACTTGCTGAAGAGCCAGTAGAAGTTGCCAATGTTCCTAAACTTCGTGATGTTGATACAA
CGATAGAGTTACTGCAACGCTTAGGCGCTAAGGTTTCTCGTAATGGTTCAGTTCATATTGATGCAAGCGAAGTTAATAAC
TTTTGTGCACCGTATGATTTAGTTAAAACGATGCGTGCATCAATTTGGGCACTCGGTCCATTGGTTGCACGTTTTGGTAA
AGGCCAAGTATCTTTACCTGGTGGTTGTGCTATTGGTGCTCGTCCTGTTGACCTTCATATTCACGGTCTTGAGCAACTGG
GTGCAACTATTAAGCTTGAAGACGGTTACGTTAAAGCTGAAGTTGATGGCCGCTTAAAAGGCGCACACATCGTTATGGAT
AAAGTCAGTGTTGGCGCAACCATCACGGTTATGTGTGCAGCGACTTTGGCTGAAGGCACGACTATTTTAGAAAACGCAGC
GCGTGAACCTGAGATTGTAGATACTGCTCATTTCCTTAATGCTATTGGTGCGAAAGTATCAGGTATGGGAACCGATACGA
TTACTATTGAAGGCGTTGAACGTCTTGGTGGTGGATATCATGAAGTGGTTGCTGACCGTATAGAAACGGGGACATTCCTT
GTCGCAGCTGCTGTATCTGGCGGTAAAGTCGTATGTAAAAATACGAAAGCGAGCCTACTTGAATCTGTTTTGGCTAAGCT
TGAAGAAGCGGGCGCTAAAGTTGAATCTGGTGAAGACTGGATCAGTTTAGACATGACAGGCCGAGAGCTAAAAGCGGTAA
ATATCCGTACGGCTCCACATCCTGCATTTCCAACAGACATGCAAGCGCAATTCACATTGTTAAATATGATGGCGAAAGGT
CCAGGTATTATTACGGAAACGATTTTTGAAAACCGTTTCATGCACATTCCTGAATTGCAACGTATGGGTGCTCACGCTGA
GATTGAAGGTAATACTGCTATTTGTGGTGATACTGATGGTTTAAGTGGTGCTCAAGTAATGGCAACAGATTTAAGAGCCT
CTGCAAGCCTTGTTATCGCAGGTTGTATAGCAAAAGGTGAAACAATTGTTGATCGTATTTATCATATCGACCGTGGTTAT
GATAAGATCGAAGACAAGTTAACCGCATTAGGCGCGAATATCGAAAGAGTTCGTAGTAGCGAATTATAA

Upstream 100 bases:

>100_bases
CTCAACAAATACTATTCACGCTCTATCAATCAAAGCGTTTACTCCGGAAGAGTGGGCACGTGATAAAAAATTAAATAGCT
TATTCTAAGAGGCCTTTTGA

Downstream 100 bases:

>100_bases
TCTTCACGATTATTTAGGCTACATCAGTACTAAAGTGGAAACCGGGTATATATGACCCGGTTTTTTATTGTTTGTAATAT
AAGTACACTGAATTAGATAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFAALLAEEPVEVANVPKLRDVDTTIELLQRLGAKVSRNGSVHIDASEVNN
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEDGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTILENAAREPEIVDTAHFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKVVCKNTKASLLESVLAKLEEAGAKVESGEDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
PGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGY
DKIEDKLTALGANIERVRSSEL

Sequences:

>Translated_422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFAALLAEEPVEVANVPKLRDVDTTIELLQRLGAKVSRNGSVHIDASEVNN
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEDGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTILENAAREPEIVDTAHFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKVVCKNTKASLLESVLAKLEEAGAKVESGEDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
PGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGY
DKIEDKLTALGANIERVRSSEL
>Mature_422_residues
MYKFRIQGSDKPLSGEVTISGAKNAALPILFAALLAEEPVEVANVPKLRDVDTTIELLQRLGAKVSRNGSVHIDASEVNN
FCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEDGYVKAEVDGRLKGAHIVMD
KVSVGATITVMCAATLAEGTTILENAAREPEIVDTAHFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
VAAAVSGGKVVCKNTKASLLESVLAKLEEAGAKVESGEDWISLDMTGRELKAVNIRTAPHPAFPTDMQAQFTLLNMMAKG
PGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGY
DKIEDKLTALGANIERVRSSEL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=79.9043062200957, Blast_Score=694, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_ALISL (B6EMB5)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262034.1
- GeneID:   6986533
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0511
- HOGENOM:   HBG482701
- OMA:   ICGDTDG
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44767; Mature: 44767

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFRIQGSDKPLSGEVTISGAKNAALPILFAALLAEEPVEVANVPKLRDVDTTIELLQR
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHH
LGAKVSRNGSVHIDASEVNNFCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGA
HCCHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDLHIHGLEQLGATIKLEDGYVKAEVDGRLKGAHIVMDKVSVGATITVMCAATLAEGT
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEHHHHHCCH
TILENAAREPEIVDTAHFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHCCCEEE
VAAAVSGGKVVCKNTKASLLESVLAKLEEAGAKVESGEDWISLDMTGRELKAVNIRTAPH
EEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEECCCC
PAFPTDMQAQFTLLNMMAKGPGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEEECCCCC
LSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGYDKIEDKLTALGANIERVRSS
CCCCCEEHHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCC
EL
CC
>Mature Secondary Structure
MYKFRIQGSDKPLSGEVTISGAKNAALPILFAALLAEEPVEVANVPKLRDVDTTIELLQR
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHH
LGAKVSRNGSVHIDASEVNNFCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGA
HCCHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDLHIHGLEQLGATIKLEDGYVKAEVDGRLKGAHIVMDKVSVGATITVMCAATLAEGT
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEHHHHHCCH
TILENAAREPEIVDTAHFLNAIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHCCCEEE
VAAAVSGGKVVCKNTKASLLESVLAKLEEAGAKVESGEDWISLDMTGRELKAVNIRTAPH
EEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEECCCC
PAFPTDMQAQFTLLNMMAKGPGIITETIFENRFMHIPELQRMGAHAEIEGNTAICGDTDG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEEECCCCC
LSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGYDKIEDKLTALGANIERVRSS
CCCCCEEHHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCC
EL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA