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The map label for this gene is yrbG [H]

Identifier: 209694099

GI number: 209694099

Start: 562544

End: 563512

Strand: Reverse

Name: yrbG [H]

Synonym: VSAL_I0504

Alternate gene names: 209694099

Gene position: 563512-562544 (Counterclockwise)

Preceding gene: 209694108

Following gene: 209694098

Centisome position: 16.95

GC content: 40.76

Gene sequence:

>969_bases
ATGACAGAGCTGCTTATGCCATCTCTACTTCTTGTCGTAGGACTCTCTTTACTTGTTTGGGGCGCCGATAAATTGGTATT
TGGTTCTGCCGCATTAGCGAAGAACTATGGTATCTCTCCCCTTGTCATTGGTATGACTATATTAGCGATGGGTTCATCTG
CCCCAGAAATGATGGTTTCTGCTGCTGCCGCCTTAGATGGAAAAACAGATACCGCTGTTGGTAATGTCATTGGCTCTAAC
ATCGCTAACATCGCATTAATTTTAGGTATTACTGCCTTAATTAAACCACTAGCCATTAGCTCTGGCATCATTCGCCGTGA
ACTACCTCTGATGTTGATCGTAACATTGCTGGCTGGTGGCATCATGTATGATAACTACCTAGGATTTAATGAAGGCATTT
TACTTGTTGCTCTTTTCATCGCTTTTATTCTTGCGATGTTATATATCAGCCGAAAAGAACAACCCAATGGTGACACGCTA
CTTAATGAACAAGAATCAGAGATCCCTGATGGTGTTCCTAACGGAAAAGCAATTTTCTGGGTGGTAGTTGGCCTTGCACT
GTTACCATTAGGCGCAAATATGCTGATTGATAACGCGGTTATTATTGCAAAACATTTTGGTATGAGTGATTTAGTTATTG
GTTTAACAATTATTGCTATCGGAACAAGTCTTCCTGAACTTGCCGCATCTGTTGCGGGTGTATTGAAAGGCGAAGATGAC
ATGGCTGTTGGTAATATTATTGGTTCTAACGTATTCAATATTCTTGCCGTTATGGGGATCCCTGCACTTCTACACCCATC
AAGTATCAGTGAATATATTATGAGCCGTGACTTCTACGTAATGTTAGGCGTTTCTGTTTTACTTCTTATTATGGCGTTGG
GTAAAAGTCGCAGCATTAACCGTATTGAAGGTGGTATTTTAGTGACGTGTTTCCTTATATATCAAGGATTCCTTTTCTAC
ACGATGTAA

Upstream 100 bases:

>100_bases
CATCATTTAAAGACAACCTTTTTCCTTTCTTTTTTGTCATATAAACGTCAAAATTAGGGGTTAACTATAATAATCATCAT
TACAAAAGGAAATTAATACA

Downstream 100 bases:

>100_bases
TCATCTACCCCGTTTAATAGAAAAATAGGTAGGTTAGTTAATAAAAAACACTTTATTAATTAGCTACCTATCTATTTTTT
ACCTCCCCCTCCTTATAACT

Product: sodium/calcium exchanger protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTELLMPSLLLVVGLSLLVWGADKLVFGSAALAKNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSN
IANIALILGITALIKPLAISSGIIRRELPLMLIVTLLAGGIMYDNYLGFNEGILLVALFIAFILAMLYISRKEQPNGDTL
LNEQESEIPDGVPNGKAIFWVVVGLALLPLGANMLIDNAVIIAKHFGMSDLVIGLTIIAIGTSLPELAASVAGVLKGEDD
MAVGNIIGSNVFNILAVMGIPALLHPSSISEYIMSRDFYVMLGVSVLLLIMALGKSRSINRIEGGILVTCFLIYQGFLFY
TM

Sequences:

>Translated_322_residues
MTELLMPSLLLVVGLSLLVWGADKLVFGSAALAKNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSN
IANIALILGITALIKPLAISSGIIRRELPLMLIVTLLAGGIMYDNYLGFNEGILLVALFIAFILAMLYISRKEQPNGDTL
LNEQESEIPDGVPNGKAIFWVVVGLALLPLGANMLIDNAVIIAKHFGMSDLVIGLTIIAIGTSLPELAASVAGVLKGEDD
MAVGNIIGSNVFNILAVMGIPALLHPSSISEYIMSRDFYVMLGVSVLLLIMALGKSRSINRIEGGILVTCFLIYQGFLFY
TM
>Mature_321_residues
TELLMPSLLLVVGLSLLVWGADKLVFGSAALAKNYGISPLVIGMTILAMGSSAPEMMVSAAAALDGKTDTAVGNVIGSNI
ANIALILGITALIKPLAISSGIIRRELPLMLIVTLLAGGIMYDNYLGFNEGILLVALFIAFILAMLYISRKEQPNGDTLL
NEQESEIPDGVPNGKAIFWVVVGLALLPLGANMLIDNAVIIAKHFGMSDLVIGLTIIAIGTSLPELAASVAGVLKGEDDM
AVGNIIGSNVFNILAVMGIPALLHPSSISEYIMSRDFYVMLGVSVLLLIMALGKSRSINRIEGGILVTCFLIYQGFLFYT
M

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI45504369, Length=387, Percent_Identity=26.0981912144703, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789587, Length=304, Percent_Identity=44.4078947368421, Blast_Score=240, Evalue=7e-65,
Organism=Drosophila melanogaster, GI24583109, Length=124, Percent_Identity=38.7096774193548, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24583111, Length=124, Percent_Identity=38.7096774193548, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33912; Mature: 33781

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELLMPSLLLVVGLSLLVWGADKLVFGSAALAKNYGISPLVIGMTILAMGSSAPEMMVS
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
AAAALDGKTDTAVGNVIGSNIANIALILGITALIKPLAISSGIIRRELPLMLIVTLLAGG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
IMYDNYLGFNEGILLVALFIAFILAMLYISRKEQPNGDTLLNEQESEIPDGVPNGKAIFW
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCHHHH
VVVGLALLPLGANMLIDNAVIIAKHFGMSDLVIGLTIIAIGTSLPELAASVAGVLKGEDD
HHHHHHHHHCCCHHHHCCCEEEEHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
MAVGNIIGSNVFNILAVMGIPALLHPSSISEYIMSRDFYVMLGVSVLLLIMALGKSRSIN
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCH
RIEGGILVTCFLIYQGFLFYTM
HHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TELLMPSLLLVVGLSLLVWGADKLVFGSAALAKNYGISPLVIGMTILAMGSSAPEMMVS
CHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
AAAALDGKTDTAVGNVIGSNIANIALILGITALIKPLAISSGIIRRELPLMLIVTLLAGG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
IMYDNYLGFNEGILLVALFIAFILAMLYISRKEQPNGDTLLNEQESEIPDGVPNGKAIFW
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCHHHH
VVVGLALLPLGANMLIDNAVIIAKHFGMSDLVIGLTIIAIGTSLPELAASVAGVLKGEDD
HHHHHHHHHCCCHHHHCCCEEEEHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
MAVGNIIGSNVFNILAVMGIPALLHPSSISEYIMSRDFYVMLGVSVLLLIMALGKSRSIN
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCH
RIEGGILVTCFLIYQGFLFYTM
HHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]