Click here to switch to the map view.

The map label for this gene is lptA [H]

Identifier: 209694095

GI number: 209694095

Start: 559768

End: 560268

Strand: Reverse

Name: lptA [H]

Synonym: VSAL_I0500

Alternate gene names: 209694095

Gene position: 560268-559768 (Counterclockwise)

Preceding gene: 209694096

Following gene: 209694094

Centisome position: 16.85

GC content: 37.13

Gene sequence:

>501_bases
ATGAAGCTTTCACACGTTAGTCTACTTGCCGGTTTATTATTCAGTTCTTCAAGTTGGGCATTAAGCACCGATACAGAACA
ACCGATTCATATTAATTCAGACACTCAAAACTTTGATATGCAAAGTAACAGAGTGACCTTCAACGGTGATGTTACTTTAA
AACAAGGCAGCATTAAGATATTTGCAGATAAACTTATTGTTATACGTCCTCAAGGCCAAGAAGGCAGAGAAATTCTTGAA
GCGTACGGAAAGCCAGCTCGTTTTAGTCAATTAACCGATGACGGTAAAACACTGAGAGGGAAAGCAAATAAATTGCGTTA
TGAGCTAGAAAATGAATTTCTAACAATGACGGACAATGCTGAACTAACCCAAGACGACAGTGTTATTCAGGGTAAAGTGA
TTACCTATAATATGAAGACACAAAAGTTAATTGCGGATGGTGGTAAAGACGAACGAGTCACTACTATTCTCCAACCTAGT
CAATTGAATAAAAAACAATAA

Upstream 100 bases:

>100_bases
GTCAATCTGGTTGGCCCAACTTTCGAAACTACTGGTGTAGGAATGAAAGGTAATTTCACTAGCCAACAAACGACCCTATT
AGAGAATGTACAAGGTATCT

Downstream 100 bases:

>100_bases
TTATGGCCATATTAGAAGCAAAAAACCTCGCAAAAACATACGGCAGCCGTAAAGTCGTATCTGATGTAAGCCTAACGGTT
GAGTCAGGGAAAATTGTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKLSHVSLLAGLLFSSSSWALSTDTEQPIHINSDTQNFDMQSNRVTFNGDVTLKQGSIKIFADKLIVIRPQGQEGREILE
AYGKPARFSQLTDDGKTLRGKANKLRYELENEFLTMTDNAELTQDDSVIQGKVITYNMKTQKLIADGGKDERVTTILQPS
QLNKKQ

Sequences:

>Translated_166_residues
MKLSHVSLLAGLLFSSSSWALSTDTEQPIHINSDTQNFDMQSNRVTFNGDVTLKQGSIKIFADKLIVIRPQGQEGREILE
AYGKPARFSQLTDDGKTLRGKANKLRYELENEFLTMTDNAELTQDDSVIQGKVITYNMKTQKLIADGGKDERVTTILQPS
QLNKKQ
>Mature_166_residues
MKLSHVSLLAGLLFSSSSWALSTDTEQPIHINSDTQNFDMQSNRVTFNGDVTLKQGSIKIFADKLIVIRPQGQEGREILE
AYGKPARFSQLTDDGKTLRGKANKLRYELENEFLTMTDNAELTQDDSVIQGKVITYNMKTQKLIADGGKDERVTTILQPS
QLNKKQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=166, Percent_Identity=50.6024096385542, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 18607; Mature: 18607

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSHVSLLAGLLFSSSSWALSTDTEQPIHINSDTQNFDMQSNRVTFNGDVTLKQGSIKI
CCCHHHHHHHHHHHCCCCCEEECCCCCCEEECCCCCCCCCCCCEEEECCCEEEECCCEEE
FADKLIVIRPQGQEGREILEAYGKPARFSQLTDDGKTLRGKANKLRYELENEFLTMTDNA
EEEEEEEEECCCCCHHHHHHHCCCCCCHHHCCCCCCEECCCCHHEEEEECCCEEEEECCC
ELTQDDSVIQGKVITYNMKTQKLIADGGKDERVTTILQPSQLNKKQ
CCCCCCCEEEEEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKLSHVSLLAGLLFSSSSWALSTDTEQPIHINSDTQNFDMQSNRVTFNGDVTLKQGSIKI
CCCHHHHHHHHHHHCCCCCEEECCCCCCEEECCCCCCCCCCCCEEEECCCEEEECCCEEE
FADKLIVIRPQGQEGREILEAYGKPARFSQLTDDGKTLRGKANKLRYELENEFLTMTDNA
EEEEEEEEECCCCCHHHHHHHCCCCCCHHHCCCCCCEECCCCHHEEEEECCCEEEEECCC
ELTQDDSVIQGKVITYNMKTQKLIADGGKDERVTTILQPSQLNKKQ
CCCCCCCEEEEEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]