Click here to switch to the map view.

The map label for this gene is mreD [H]

Identifier: 209694080

GI number: 209694080

Start: 542927

End: 543418

Strand: Direct

Name: mreD [H]

Synonym: VSAL_I0485

Alternate gene names: 209694080

Gene position: 542927-543418 (Clockwise)

Preceding gene: 209694079

Following gene: 209694081

Centisome position: 16.33

GC content: 40.24

Gene sequence:

>492_bases
ATGACGAGTAGTCATCTTATGCGTGGAAGAGTCATTATTTGGCTCTCTTTTTTGATCGCATTAATATTACAGGCGGCACC
TTGGCCTGGAACATTAGAAGTATTACGACCTTCTTGGATCATATTAGTGACTTTCTATTGGGTATTAGCATTGCCTCATC
GGGTTAATGTTGGTACTGCCATGATACTTGGGATCTTATGGGATCTATTACTTGGCACAACGCTTGGTATCCGTGGAATG
ACGATGGCGATTTTGGTCTATCTGGTTGCTGCGAATTTTAAGTTGTTGAGAAACCTTGCTCTTTGGCAACAAGCTGCAAT
CTTCTCAGCATTAACGTTACTGGGTAAACTCTTAGAATTTTTAGGCGAATTTTTAGTTCATGATGTGTCATTCAACGGAC
ATTTTTTATGGGCGGGCGTGTTAAACTTTATTTTGTGGCCTTGGTTATTTTTATTGATGCGTAGAGTTCGCCGTCATTGG
TCTATTCGATAA

Upstream 100 bases:

>100_bases
GCATCGATAGAATTAGAAACTGCGGTTGAATTTGATAAATTAAGATATTTATTACTCGTATGGCCAACAGAAATTGAAGG
TAAGATAAAGGAAGTGACTA

Downstream 100 bases:

>100_bases
GGAAGTAAAATGTCGAATCAATTATTTTTAGCATCTGGTTCTCCACGTAGAAAGGAACTGCTGCAACAGTTAGGGTATCA
GTTTGAGATAGTTACTGTTG

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTSSHLMRGRVIIWLSFLIALILQAAPWPGTLEVLRPSWIILVTFYWVLALPHRVNVGTAMILGILWDLLLGTTLGIRGM
TMAILVYLVAANFKLLRNLALWQQAAIFSALTLLGKLLEFLGEFLVHDVSFNGHFLWAGVLNFILWPWLFLLMRRVRRHW
SIR

Sequences:

>Translated_163_residues
MTSSHLMRGRVIIWLSFLIALILQAAPWPGTLEVLRPSWIILVTFYWVLALPHRVNVGTAMILGILWDLLLGTTLGIRGM
TMAILVYLVAANFKLLRNLALWQQAAIFSALTLLGKLLEFLGEFLVHDVSFNGHFLWAGVLNFILWPWLFLLMRRVRRHW
SIR
>Mature_162_residues
TSSHLMRGRVIIWLSFLIALILQAAPWPGTLEVLRPSWIILVTFYWVLALPHRVNVGTAMILGILWDLLLGTTLGIRGMT
MAILVYLVAANFKLLRNLALWQQAAIFSALTLLGKLLEFLGEFLVHDVSFNGHFLWAGVLNFILWPWLFLLMRRVRRHWS
IR

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=161, Percent_Identity=52.1739130434783, Blast_Score=172, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18775; Mature: 18644

Theoretical pI: Translated: 12.10; Mature: 12.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSHLMRGRVIIWLSFLIALILQAAPWPGTLEVLRPSWIILVTFYWVLALPHRVNVGTA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
MILGILWDLLLGTTLGIRGMTMAILVYLVAANFKLLRNLALWQQAAIFSALTLLGKLLEF
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEFLVHDVSFNGHFLWAGVLNFILWPWLFLLMRRVRRHWSIR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSSHLMRGRVIIWLSFLIALILQAAPWPGTLEVLRPSWIILVTFYWVLALPHRVNVGTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
MILGILWDLLLGTTLGIRGMTMAILVYLVAANFKLLRNLALWQQAAIFSALTLLGKLLEF
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEFLVHDVSFNGHFLWAGVLNFILWPWLFLLMRRVRRHWSIR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]