| Definition | Aliivibrio salmonicida LFI1238 chromosome 1, complete genome. |
|---|---|
| Accession | NC_011312 |
| Length | 3,325,165 |
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The map label for this gene is uvrA [H]
Identifier: 209694046
GI number: 209694046
Start: 500682
End: 503510
Strand: Reverse
Name: uvrA [H]
Synonym: VSAL_I0447
Alternate gene names: 209694046
Gene position: 503510-500682 (Counterclockwise)
Preceding gene: 209694047
Following gene: 209694045
Centisome position: 15.14
GC content: 40.16
Gene sequence:
>2829_bases ATGGATAAAATTGAAGTTAGAGGGGCCAGAACCCACAACCTAAAAAATATTAGCTTAACACTCCCACGTGATAAATTAAT TGTGATAACTGGGTTATCTGGGTCAGGTAAATCTTCTTTGGCATTTGATACATTATATGCAGAAGGTCAACGACGTTATG TTGAGTCATTATCTGCTTATGCCCGTCAATTTTTATCTCTTATGGAAAAACCCGATGTAGACCATATCGAAGGGTTGTCT CCTGCTATCTCTATCGAACAAAAATCCACATCTCATAACCCAAGATCTACCGTGGGTACCATTACTGAAATCTACGATTA TTTGCGTTTACTATACGCTCGTATTGGTGAACCCCGCTGCCCTGAGCATCATGTCGAACTTACTGCTCAAACCGTTAGTC AAATGGTAGATAAAGCCTTAGAACTGCCGGAAGGCACTAAGCTTATGTTACTCGCTCCTATTATTAAGGAGCGTAAAGGC GAGCATGTTAAAACATTAGAAAATCTAGCAGCACAAGGCTTTATTCGAGCCCGTATTGATGGTGAAGTATGTGATCTTTC CGATCCACCCACATTAGAGTTACACAAAAAACACACCATTGAAGTTGTCGTTGATCGGTTTAAAGTCCGTTCAGATCTTC AACAGCGTTTAGCAGAATCGTTTGAAACGGCATTAGAACTAACCGGTGGCATTGCCGTTATCGACTATATGGATAAGACC GATAATGAACCACTGATCTTTTCGGCTAATTTTGCTTGCCCACATTGTGGTTATAGCATGCAAGAACTCGAACCTCGCTT ATTCTCTTTCAATAATCCAGCAGGGGCTTGTGGTACCTGTGATGGCTTAGGTGTACAACAATATTTCGATGCCGATAGAA TCGTTTTAGATAACAAACTTAGTATTGCTGAAGGGGCGATCAAAGGATGGGATCAAAAGAACTATTACTACTTCCAAATG CTAACTTCTCTCGCTGAACACTATACTTTTGACCTTTTCTCACCCTTTAAATCATTGTCAAAAAAAATTCAACAAATCAT CCTTAATGGCTCTGGTAATGAAGAAGTTGAATTTCATTACAGTAATGACCGGGGTGATTTACGTGTAAAACGTCACCCAT TTGAAGGTATTTTAAATACTTTAGATCGCCGCTATAAAGAAACAGAATCAAGCTCCGTTCGTGATGATTTATCCAAATAC ATTTCTACACAATCTTGCTCTAGTTGCCATGGGACTCGCCTACGCTTAGAAGCAAGAAGCGTTTTTGTCGCTGATACCAC GTTATCTGAAATCTGTGAAATGAGCATTCAAGATTCGATGGCATTTTTCAGCTCATTAACCTTAACAGGACAAAAAGCAC AAATTGCCGATAAGATAATGAAAGAAATAAACGAGCGCTTAAATTTTCTTATTAATGTTGGTCTAAATTACCTTAATTTA TCGCGCGGTGCGGACACCCTTTCTGGCGGAGAAGCTCAACGAATACGTCTTGCTAGTCAAATTGGCGCAGGGCTTGTAGG TGTTATGTATGTACTTGATGAACCATCAATTGGGCTCCATCAACGCGACAATGAACGATTATTAAAAACGTTGAATCATT TACGTGATCTCGGAAATACGGTGATTGTCGTTGAGCATGATGAAGATGCAATTCGAAGTGCCGATCATATTATTGATATA GGCCCTGGAGCCGGTGTTCATGGTGGATATATTGTTGCTGAAGGCGATTATGCGGCAATCATTAATAACCCAGACTCTTT AACAGGCCAATACTTAAGTGGCGCAAAAAAAATCCCGGTACCAAAAGAACGAGTTAAAGCGGACCCTAAAAAACAAGTAG AACTGATTGGCGCGACTGGTAATAATTTAAAAAATGTCACATTAAAATTACCGGTTGGTCTCTTTACTTGTATCACTGGT GTTTCTGGTTCTGGTAAATCGACACTCATTAACGATACTTTTTTCAAGATTGCACATACTCAATTAAATGGAGCGACAAC TTCAGAGCCCGCGCCTTATAAAAAAATTAAAGGCATCGAACACTTTGATAAAGTCATCGATATAGATCAAAGTCCAATAG GCCGAACCCCTCGCTCAAACCCCGCGACTTATACTGGTATTTTTACTCCAATACGAGAGTTATTCTCTGGAACACCGGAA TCCCGATCTCGTGGCTATAAACCTGGACGCTTTAGTTTTAATGTTCGAGGTGGCCGTTGTGAAGCTTGCCAAGGTGATGG GGTTATAAAAGTAGAAATGCATTTCTTACCTGATGTTTATGTACCATGTGATGTGTGTAAGAGTAAACGCTACAACCGTG AAACGCTTGAAGTAAAATATAAAGGTAAGAGTATTGATGAAGTTCTTCAGATGACTATTGAAGATGCTCATACTTTCTTT GCTCCTGTTCCCGTGATTGCTCGCAAATTAAAAACACTCATGGATGTAGGACTCTCTTACATTCGTTTAGGTCAAGCGGC AACGACTTTGTCTGGAGGGGAGGCTCAACGAGTCAAACTAGCTCGAGAATTATCGAAAAGAGATACTGGAAAAACACTCT ATATTTTAGATGAGCCAACTACTGGTTTGCATTTTCATGATATTCAACAACTATTGACTGTGCTTCATCACTTACGTGAA CGAGGAAATACCATTGTGGTTATTGAGCATAATCTAGATGTAGTAAAAACAGCTGACTGGGTGGTAGATTTAGGGCCAGA AGGTGGTAATGGTGGTGGAGAGATTATTGCAGAAGGAACCCCCGAAGAAGTTGCACTTGTTGAAGGCTCACATACGGCAC GCTTCTTAAAACCAATGCTTTCCTTATAA
Upstream 100 bases:
>100_bases CTACCTTATCATTACTGTTTTTTTATCCAGTACCTCTTTGTTGTTCTAATAGTCTGTGCAATACTTAGTCTTCAGTCATT ATTTATGCAGTGAGATCCCA
Downstream 100 bases:
>100_bases AATTCCATACTTATTAAGTATTATCGGATAGAATAAAGCCAGCACTTTGCTGGCTTTATTACAGGGATTAATTGAAAAAA TGGCAACCTTACTTACTCAG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 942; Mature: 942
Protein sequence:
>942_residues MDKIEVRGARTHNLKNISLTLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARIGEPRCPEHHVELTAQTVSQMVDKALELPEGTKLMLLAPIIKERKG EHVKTLENLAAQGFIRARIDGEVCDLSDPPTLELHKKHTIEVVVDRFKVRSDLQQRLAESFETALELTGGIAVIDYMDKT DNEPLIFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDADRIVLDNKLSIAEGAIKGWDQKNYYYFQM LTSLAEHYTFDLFSPFKSLSKKIQQIILNGSGNEEVEFHYSNDRGDLRVKRHPFEGILNTLDRRYKETESSSVRDDLSKY ISTQSCSSCHGTRLRLEARSVFVADTTLSEICEMSIQDSMAFFSSLTLTGQKAQIADKIMKEINERLNFLINVGLNYLNL SRGADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLNHLRDLGNTVIVVEHDEDAIRSADHIIDI GPGAGVHGGYIVAEGDYAAIINNPDSLTGQYLSGAKKIPVPKERVKADPKKQVELIGATGNNLKNVTLKLPVGLFTCITG VSGSGKSTLINDTFFKIAHTQLNGATTSEPAPYKKIKGIEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTPE SRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKSKRYNRETLEVKYKGKSIDEVLQMTIEDAHTFF APVPVIARKLKTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHHLRE RGNTIVVIEHNLDVVKTADWVVDLGPEGGNGGGEIIAEGTPEEVALVEGSHTARFLKPMLSL
Sequences:
>Translated_942_residues MDKIEVRGARTHNLKNISLTLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARIGEPRCPEHHVELTAQTVSQMVDKALELPEGTKLMLLAPIIKERKG EHVKTLENLAAQGFIRARIDGEVCDLSDPPTLELHKKHTIEVVVDRFKVRSDLQQRLAESFETALELTGGIAVIDYMDKT DNEPLIFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDADRIVLDNKLSIAEGAIKGWDQKNYYYFQM LTSLAEHYTFDLFSPFKSLSKKIQQIILNGSGNEEVEFHYSNDRGDLRVKRHPFEGILNTLDRRYKETESSSVRDDLSKY ISTQSCSSCHGTRLRLEARSVFVADTTLSEICEMSIQDSMAFFSSLTLTGQKAQIADKIMKEINERLNFLINVGLNYLNL SRGADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLNHLRDLGNTVIVVEHDEDAIRSADHIIDI GPGAGVHGGYIVAEGDYAAIINNPDSLTGQYLSGAKKIPVPKERVKADPKKQVELIGATGNNLKNVTLKLPVGLFTCITG VSGSGKSTLINDTFFKIAHTQLNGATTSEPAPYKKIKGIEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTPE SRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKSKRYNRETLEVKYKGKSIDEVLQMTIEDAHTFF APVPVIARKLKTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHHLRE RGNTIVVIEHNLDVVKTADWVVDLGPEGGNGGGEIIAEGTPEEVALVEGSHTARFLKPMLSL >Mature_942_residues MDKIEVRGARTHNLKNISLTLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARIGEPRCPEHHVELTAQTVSQMVDKALELPEGTKLMLLAPIIKERKG EHVKTLENLAAQGFIRARIDGEVCDLSDPPTLELHKKHTIEVVVDRFKVRSDLQQRLAESFETALELTGGIAVIDYMDKT DNEPLIFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDADRIVLDNKLSIAEGAIKGWDQKNYYYFQM LTSLAEHYTFDLFSPFKSLSKKIQQIILNGSGNEEVEFHYSNDRGDLRVKRHPFEGILNTLDRRYKETESSSVRDDLSKY ISTQSCSSCHGTRLRLEARSVFVADTTLSEICEMSIQDSMAFFSSLTLTGQKAQIADKIMKEINERLNFLINVGLNYLNL SRGADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLNHLRDLGNTVIVVEHDEDAIRSADHIIDI GPGAGVHGGYIVAEGDYAAIINNPDSLTGQYLSGAKKIPVPKERVKADPKKQVELIGATGNNLKNVTLKLPVGLFTCITG VSGSGKSTLINDTFFKIAHTQLNGATTSEPAPYKKIKGIEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTPE SRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKSKRYNRETLEVKYKGKSIDEVLQMTIEDAHTFF APVPVIARKLKTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHHLRE RGNTIVVIEHNLDVVKTADWVVDLGPEGGNGGGEIIAEGTPEEVALVEGSHTARFLKPMLSL
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=78.936170212766, Blast_Score=1540, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104329; Mature: 104329
Theoretical pI: Translated: 6.63; Mature: 6.63
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKIEVRGARTHNLKNISLTLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARIGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHHVELTAQTVSQMVDKALELPEGTKLMLLAPIIKERKGEHVKTLENLAAQGFIRARID CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPTLELHKKHTIEVVVDRFKVRSDLQQRLAESFETALELTGGIAVIDYMDKT CCEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC DNEPLIFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDADRIVLDNKL CCCCEEEECCCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCC SIAEGAIKGWDQKNYYYFQMLTSLAEHYTFDLFSPFKSLSKKIQQIILNGSGNEEVEFHY HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEE SNDRGDLRVKRHPFEGILNTLDRRYKETESSSVRDDLSKYISTQSCSSCHGTRLRLEARS CCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECE VFVADTTLSEICEMSIQDSMAFFSSLTLTGQKAQIADKIMKEINERLNFLINVGLNYLNL EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE SRGADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLNHLRDLGNT CCCCCCCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCE VIVVEHDEDAIRSADHIIDIGPGAGVHGGYIVAEGDYAAIINNPDSLTGQYLSGAKKIPV EEEEECCHHHHHCCCCEEECCCCCCCCCCEEEECCCEEEEECCCCHHCHHHHCCCCCCCC PKERVKADPKKQVELIGATGNNLKNVTLKLPVGLFTCITGVSGSGKSTLINDTFFKIAHT CHHHHCCCCCCCEEEEECCCCCCEEEEEEECHHHHHHHHCCCCCCCCEEECCHHHEEEEE QLNGATTSEPAPYKKIKGIEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTPE ECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCC SRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKSKRYNRETLEVKY HHHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEE KGKSIDEVLQMTIEDAHTFFAPVPVIARKLKTLMDVGLSYIRLGQAATTLSGGEAQRVKL CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHCCCCCCHHHHHH ARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHHLRERGNTIVVIEHNLDVVKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE VVDLGPEGGNGGGEIIAEGTPEEVALVEGSHTARFLKPMLSL EEEECCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHCC >Mature Secondary Structure MDKIEVRGARTHNLKNISLTLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARIGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHHVELTAQTVSQMVDKALELPEGTKLMLLAPIIKERKGEHVKTLENLAAQGFIRARID CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPTLELHKKHTIEVVVDRFKVRSDLQQRLAESFETALELTGGIAVIDYMDKT CCEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC DNEPLIFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDADRIVLDNKL CCCCEEEECCCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCC SIAEGAIKGWDQKNYYYFQMLTSLAEHYTFDLFSPFKSLSKKIQQIILNGSGNEEVEFHY HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEE SNDRGDLRVKRHPFEGILNTLDRRYKETESSSVRDDLSKYISTQSCSSCHGTRLRLEARS CCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECE VFVADTTLSEICEMSIQDSMAFFSSLTLTGQKAQIADKIMKEINERLNFLINVGLNYLNL EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE SRGADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLNHLRDLGNT CCCCCCCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCE VIVVEHDEDAIRSADHIIDIGPGAGVHGGYIVAEGDYAAIINNPDSLTGQYLSGAKKIPV EEEEECCHHHHHCCCCEEECCCCCCCCCCEEEECCCEEEEECCCCHHCHHHHCCCCCCCC PKERVKADPKKQVELIGATGNNLKNVTLKLPVGLFTCITGVSGSGKSTLINDTFFKIAHT CHHHHCCCCCCCEEEEECCCCCCEEEEEEECHHHHHHHHCCCCCCCCEEECCHHHEEEEE QLNGATTSEPAPYKKIKGIEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTPE ECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCC SRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKSKRYNRETLEVKY HHHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEE KGKSIDEVLQMTIEDAHTFFAPVPVIARKLKTLMDVGLSYIRLGQAATTLSGGEAQRVKL CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHCCCCCCHHHHHH ARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHHLRERGNTIVVIEHNLDVVKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE VVDLGPEGGNGGGEIIAEGTPEEVALVEGSHTARFLKPMLSL EEEECCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]