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The map label for this gene is hemY [H]

Identifier: 209693829

GI number: 209693829

Start: 257294

End: 258475

Strand: Reverse

Name: hemY [H]

Synonym: VSAL_I0217

Alternate gene names: 209693829

Gene position: 258475-257294 (Counterclockwise)

Preceding gene: 209693830

Following gene: 209693828

Centisome position: 7.77

GC content: 41.96

Gene sequence:

>1182_bases
ATGATTCGATTGCTTCTTCTGGCCATTGTCTTAGTCGGTGGATTAATCGTTGGGACAACATTCGCAGACCAACAAGGCTA
TGTATTAATTTCCGTCGCTGAGATCACCATTGAAATGAGTTTAACAACACTTGTTCTCTTCATTGGTGCCTTAATTGCGG
GTCTTTTCTTATTAGAAATAGTCGTTAAACGCATTCTGTCAGTCAGTAATTTTACGCGTGGTTGGTTCAGTGCTCGCCAT
CTTAGAAAGGCTCGTTACAACACCTTTAAAGGCATGATTAAACTGCATGAAGGGGAATGGAAAGAAGCCGAACGTTTAAT
CACAAAGGGCGGACGCCATAACGATTTCCCGTTATTAAACTACCTCGCGGCCGCAGAAGCAGCCCAAGGTCGCCAACATA
TCGAGCAACGAGATGCCTACTTAAAGCTCGCTTCAGAACAACCAGGCAGTCACTTAGCTGTCGCATTAACCAGCGCAAAA
TTACAAATGCGTGAAGAACAATATGAATTTGCTCTTGCGACACTTCAGTCGGTTAACGTTGATTACCCTCATAATCCGGT
TTTACTCGATCTTCTAAAAGACTGTTATTTAGCCCTTAATGAATGGCAAGCATTGAAAAACATTATTCATCCGCTTACCA
AAGGGAATTTAATTACAGAGCAACAAGCGCTTGAATTAGAAGAAAAAGTGGAATGTGGCATTCTCGCTTTAATTGCGACG
AATAAGGGCACCACGGGGCTATTAGACCATTGGCAAAGCTTACCGAAAAAGCTAAAAAAACACATCCCCATTTTAGTGTG
TTTAATTCGACAATTACACAATCGCAAAGCCGATTCTGAAGCGTATATCCTATTACGAGATAACCTAAAGAAACGCAATG
ATGATCGCTTAATTGAGTTATTGCCAACCTTAAATCTGCCTGATTATCACCCAGCTACGGTACTGCTTGAAGATTTAGCA
CGCTACGATATTCGTAACCCAATAATTCAAAGCACACTGGCTCAACTTTATATGCGAACTCAAAAATGGCAACCGGCTCG
CGAACATTTTGAAGCGGCATTGGCCATCCGCGAAGACATGTCAGATTACGCCTATCTTGCTCGGGTTTTAGATAAGCAAA
ACAGAAAACAAGCCGCTGCGGACATTTCTCGAAAAGCATTAACCATGGTTGATGATATCTAA

Upstream 100 bases:

>100_bases
TTCTGTCTGATTTCATTTCAGAACGTCTACGCCGCAATATCCAAGCGGTTGGTACAACAACGCCCGAGACTAAAACCGCA
ACAATAGAAGGAGGTAAATC

Downstream 100 bases:

>100_bases
TCCGTAAGCGTGCGGGGAACTACACCTAACAAATAAAATTCATTATGCGTATCTTACGATCTTTCATTTAACGAGAACGT
AATTATGCAAAAAGATAAAA

Product: protein HemY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIRLLLLAIVLVGGLIVGTTFADQQGYVLISVAEITIEMSLTTLVLFIGALIAGLFLLEIVVKRILSVSNFTRGWFSARH
LRKARYNTFKGMIKLHEGEWKEAERLITKGGRHNDFPLLNYLAAAEAAQGRQHIEQRDAYLKLASEQPGSHLAVALTSAK
LQMREEQYEFALATLQSVNVDYPHNPVLLDLLKDCYLALNEWQALKNIIHPLTKGNLITEQQALELEEKVECGILALIAT
NKGTTGLLDHWQSLPKKLKKHIPILVCLIRQLHNRKADSEAYILLRDNLKKRNDDRLIELLPTLNLPDYHPATVLLEDLA
RYDIRNPIIQSTLAQLYMRTQKWQPAREHFEAALAIREDMSDYAYLARVLDKQNRKQAAADISRKALTMVDDI

Sequences:

>Translated_393_residues
MIRLLLLAIVLVGGLIVGTTFADQQGYVLISVAEITIEMSLTTLVLFIGALIAGLFLLEIVVKRILSVSNFTRGWFSARH
LRKARYNTFKGMIKLHEGEWKEAERLITKGGRHNDFPLLNYLAAAEAAQGRQHIEQRDAYLKLASEQPGSHLAVALTSAK
LQMREEQYEFALATLQSVNVDYPHNPVLLDLLKDCYLALNEWQALKNIIHPLTKGNLITEQQALELEEKVECGILALIAT
NKGTTGLLDHWQSLPKKLKKHIPILVCLIRQLHNRKADSEAYILLRDNLKKRNDDRLIELLPTLNLPDYHPATVLLEDLA
RYDIRNPIIQSTLAQLYMRTQKWQPAREHFEAALAIREDMSDYAYLARVLDKQNRKQAAADISRKALTMVDDI
>Mature_393_residues
MIRLLLLAIVLVGGLIVGTTFADQQGYVLISVAEITIEMSLTTLVLFIGALIAGLFLLEIVVKRILSVSNFTRGWFSARH
LRKARYNTFKGMIKLHEGEWKEAERLITKGGRHNDFPLLNYLAAAEAAQGRQHIEQRDAYLKLASEQPGSHLAVALTSAK
LQMREEQYEFALATLQSVNVDYPHNPVLLDLLKDCYLALNEWQALKNIIHPLTKGNLITEQQALELEEKVECGILALIAT
NKGTTGLLDHWQSLPKKLKKHIPILVCLIRQLHNRKADSEAYILLRDNLKKRNDDRLIELLPTLNLPDYHPATVLLEDLA
RYDIRNPIIQSTLAQLYMRTQKWQPAREHFEAALAIREDMSDYAYLARVLDKQNRKQAAADISRKALTMVDDI

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=384, Percent_Identity=32.03125, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 44653; Mature: 44653

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLLLLAIVLVGGLIVGTTFADQQGYVLISVAEITIEMSLTTLVLFIGALIAGLFLLEI
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVKRILSVSNFTRGWFSARHLRKARYNTFKGMIKLHEGEWKEAERLITKGGRHNDFPLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCHHHH
YLAAAEAAQGRQHIEQRDAYLKLASEQPGSHLAVALTSAKLQMREEQYEFALATLQSVNV
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
DYPHNPVLLDLLKDCYLALNEWQALKNIIHPLTKGNLITEQQALELEEKVECGILALIAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEC
NKGTTGLLDHWQSLPKKLKKHIPILVCLIRQLHNRKADSEAYILLRDNLKKRNDDRLIEL
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHH
LPTLNLPDYHPATVLLEDLARYDIRNPIIQSTLAQLYMRTQKWQPAREHFEAALAIREDM
HCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SDYAYLARVLDKQNRKQAAADISRKALTMVDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRLLLLAIVLVGGLIVGTTFADQQGYVLISVAEITIEMSLTTLVLFIGALIAGLFLLEI
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVKRILSVSNFTRGWFSARHLRKARYNTFKGMIKLHEGEWKEAERLITKGGRHNDFPLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCHHHH
YLAAAEAAQGRQHIEQRDAYLKLASEQPGSHLAVALTSAKLQMREEQYEFALATLQSVNV
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
DYPHNPVLLDLLKDCYLALNEWQALKNIIHPLTKGNLITEQQALELEEKVECGILALIAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEC
NKGTTGLLDHWQSLPKKLKKHIPILVCLIRQLHNRKADSEAYILLRDNLKKRNDDRLIEL
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHH
LPTLNLPDYHPATVLLEDLARYDIRNPIIQSTLAQLYMRTQKWQPAREHFEAALAIREDM
HCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SDYAYLARVLDKQNRKQAAADISRKALTMVDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]