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The map label for this gene is caiD [C]

Identifier: 209552177

GI number: 209552177

Start: 287599

End: 288399

Strand: Reverse

Name: caiD [C]

Synonym: Rleg2_6335

Alternate gene names: 209552177

Gene position: 288399-287599 (Counterclockwise)

Preceding gene: 209552178

Following gene: 209552176

Centisome position: 93.41

GC content: 57.3

Gene sequence:

>801_bases
ATGCACATACAGAAAATCATCGATGACGGCACCCTCTGGCTCACCTTGAGCAATCCTGAACAGATGAACTGTCTTGGGCT
CGCCGAATACAATGGACTCGCTGACGCCATCATCGAAGCAAGCGCCGACGATAGCCTCGATGTAATCGCCATCACCGGTT
CCGGGCGTGCATTCTGCACAGGAGGGAACCTCAAGGAAATTCAGGCCGAGCAGGCGAAGGGGGAACTGCCCGGTAAGCTA
GTCGTCCAAAAGTTTGCGGACGCGTCCTTGCGACTCTTCCAGTCTATGGAAAGCACATCAAAGACTGTAGTTGCAATTGT
AAACGGGCACTGCCATGCGGGCGGCCTGAGCATCGTTTTGAGCGCCGATATTTCGCTAGCCAGCGACCGTGCGGACTTCT
GTATACCCGAAGCAAAAGTCGGCCTTGCCGACCCCTATGCGCCTCTTCGGCTTGGCCGCGCCGTCGGGTTACCGATGGCG
CGGTGGATGATGTACACGGCCGATCGGATAACTGCGACCAAGGCACTGGAGATTTCGCTCGTCAATAAGGTTGTCCCTCA
CGATACGCTTGCTGAACAGGCGCGTTCCCTGGTCCGACAAGTTCAAAGGACTGCTCCCACCAGCCGCGCCATTTTTAAAA
GGTGCCTCAACACGGACCTACCGGCCTTCAATCGCGAGGCGATGATCGCTGCGAACGCGTCACCCGATGCGGTCGAGGGA
CTGAAGGCATTCGTCGCGCGCCGCGACCCCGTTTGGCCGTCGAGACCACTCAGGGCGAATAAGCCAAATATCAATCCCTG
A

Upstream 100 bases:

>100_bases
GTAGCGTTCATGACACTCAGCGAAATCTGCGACACCTGGAAAGATTGAACGTTCGGCGTCTCTGGCAAGTGACGCTCGCG
CGCTGTCGAATGGATAAGAC

Downstream 100 bases:

>100_bases
ACTAAGCATTTTCGATGCTGCCAGACTGACTGCAAGGAAGAAAAGATCATGTTTTCAGATGAAACAAACAGGCTGCTTGC
CCGAGGTTCCGCGATCAGTC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MHIQKIIDDGTLWLTLSNPEQMNCLGLAEYNGLADAIIEASADDSLDVIAITGSGRAFCTGGNLKEIQAEQAKGELPGKL
VVQKFADASLRLFQSMESTSKTVVAIVNGHCHAGGLSIVLSADISLASDRADFCIPEAKVGLADPYAPLRLGRAVGLPMA
RWMMYTADRITATKALEISLVNKVVPHDTLAEQARSLVRQVQRTAPTSRAIFKRCLNTDLPAFNREAMIAANASPDAVEG
LKAFVARRDPVWPSRPLRANKPNINP

Sequences:

>Translated_266_residues
MHIQKIIDDGTLWLTLSNPEQMNCLGLAEYNGLADAIIEASADDSLDVIAITGSGRAFCTGGNLKEIQAEQAKGELPGKL
VVQKFADASLRLFQSMESTSKTVVAIVNGHCHAGGLSIVLSADISLASDRADFCIPEAKVGLADPYAPLRLGRAVGLPMA
RWMMYTADRITATKALEISLVNKVVPHDTLAEQARSLVRQVQRTAPTSRAIFKRCLNTDLPAFNREAMIAANASPDAVEG
LKAFVARRDPVWPSRPLRANKPNINP
>Mature_266_residues
MHIQKIIDDGTLWLTLSNPEQMNCLGLAEYNGLADAIIEASADDSLDVIAITGSGRAFCTGGNLKEIQAEQAKGELPGKL
VVQKFADASLRLFQSMESTSKTVVAIVNGHCHAGGLSIVLSADISLASDRADFCIPEAKVGLADPYAPLRLGRAVGLPMA
RWMMYTADRITATKALEISLVNKVVPHDTLAEQARSLVRQVQRTAPTSRAIFKRCLNTDLPAFNREAMIAANASPDAVEG
LKAFVARRDPVWPSRPLRANKPNINP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI194097323, Length=244, Percent_Identity=28.2786885245902, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI221142681, Length=268, Percent_Identity=29.8507462686567, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788597, Length=251, Percent_Identity=27.8884462151394, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=26.3565891472868, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=26.9035532994924, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082183, Length=180, Percent_Identity=23.8888888888889, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=28.4, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=28.5140562248996, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=238, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=215, Percent_Identity=26.5116279069767, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=213, Percent_Identity=25.8215962441315, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=227, Percent_Identity=23.7885462555066, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=232, Percent_Identity=23.7068965517241, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=28.8065843621399, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=28.8065843621399, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=24.9027237354086, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650670, Length=249, Percent_Identity=28.1124497991968, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28644; Mature: 28644

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIQKIIDDGTLWLTLSNPEQMNCLGLAEYNGLADAIIEASADDSLDVIAITGSGRAFCT
CCHHHEECCCEEEEEECCCCCCCEEEEHHHCCHHHHHHHCCCCCCEEEEEEECCCEEEEE
GGNLKEIQAEQAKGELPGKLVVQKFADASLRLFQSMESTSKTVVAIVNGHCHAGGLSIVL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEE
SADISLASDRADFCIPEAKVGLADPYAPLRLGRAVGLPMARWMMYTADRITATKALEISL
ECCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VNKVVPHDTLAEQARSLVRQVQRTAPTSRAIFKRCLNTDLPAFNREAMIAANASPDAVEG
HHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHH
LKAFVARRDPVWPSRPLRANKPNINP
HHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHIQKIIDDGTLWLTLSNPEQMNCLGLAEYNGLADAIIEASADDSLDVIAITGSGRAFCT
CCHHHEECCCEEEEEECCCCCCCEEEEHHHCCHHHHHHHCCCCCCEEEEEEECCCEEEEE
GGNLKEIQAEQAKGELPGKLVVQKFADASLRLFQSMESTSKTVVAIVNGHCHAGGLSIVL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEE
SADISLASDRADFCIPEAKVGLADPYAPLRLGRAVGLPMARWMMYTADRITATKALEISL
ECCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VNKVVPHDTLAEQARSLVRQVQRTAPTSRAIFKRCLNTDLPAFNREAMIAANASPDAVEG
HHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHH
LKAFVARRDPVWPSRPLRANKPNINP
HHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA