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The map label for this gene is appC [H]

Identifier: 209552171

GI number: 209552171

Start: 281379

End: 282272

Strand: Reverse

Name: appC [H]

Synonym: Rleg2_6328

Alternate gene names: 209552171

Gene position: 282272-281379 (Counterclockwise)

Preceding gene: 209552172

Following gene: 209552170

Centisome position: 91.43

GC content: 56.94

Gene sequence:

>894_bases
ATGAGCACTATTCAAAACACTGCTTTGCAAAGGAAGCGCTTCAAGCCGGGCCGCAGCCGTCGGGGCCGTGCCTGGAAAGC
GCTTAGCCGCGCACCACTGAGTGCCTGGTTTGGGATTGTCGTAGTGCTGACATACGCTGGAACGGCGCTTTTCGCTCCCC
AGCTTGCCCCCTATGGCGAAGCGCAGGTATTTCCGGAACCTTTCGCACCTTGGAGCGCCGATTTCGTTCTCGGCACTGAC
CAGCTGGGCAGAGACGTCCTCACGCGCCTCATTTACGGTGCGCGGAATACCCTGGGAATCGCGGTTATAACTACGACATT
GTCGTTCTTCTTTGGGGTCTCGCTTGGTGTCACAGCTGCGCTTCTCAAAGGATGGGTCGATCAGGCACTTTCCCGATCGG
TGGACATTGTACTGTCCATTCCAGGGCTGATCTTCTCGCTTATGCTCCTTGCGATCTTCGGTTCCAACGTGTGGAGTCTC
ATTCTTATCATCGCGGTTCTCGACTCCACGAACTTCTACCGACTGGCACGCACAAGCGGCCTGTCGGTCGCCTCCATGGA
ATTTATCGAAGCCGCACGCCTGCGCGGCGAACGGCCCACATGGATTGTCTTCCGCGAAATCCTACCCAATATTCTCCCCC
CCTTGATTGCGGAGGCAGGCCTTCGCTTCTGTTTCGTTTTTCTGACCATTTCCGCTCTCTCTTTCCTGGGGGTGGGAATA
CAGCCGCCCACCGCCGACTGGGGCTCGATGGTCCGCGAGAACGCAACCTTGATCACGTACGGCGACATCACGCCGCTTCT
ACCGGCCGCAGCGATCGGGCTCCTAACGGTTGCTGTGAACTTCGTTGTCGACTGGTTTCTAACTAATCTGAGCGGAATTA
AAGATGGCCACTGA

Upstream 100 bases:

>100_bases
TTCAGGCCTGTACGCTAATTTTCGCGAGCGCCTACATCCTTCTCAATCTCGTCACCGATCTCGTCACTATTTTGACCAAT
CCGAGGCTGCTGCACCCAAG

Downstream 100 bases:

>100_bases
GACACGCGGCAGCGACGCCCGCCGCAAGGGCGGCAATCTTCTCGAGATGAGAGATCTGAAAATCAATGGTTTCAGCAACG
ACGTCTGGCACGAAATCGTC

Product: binding-protein-dependent transporters inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSTIQNTALQRKRFKPGRSRRGRAWKALSRAPLSAWFGIVVVLTYAGTALFAPQLAPYGEAQVFPEPFAPWSADFVLGTD
QLGRDVLTRLIYGARNTLGIAVITTTLSFFFGVSLGVTAALLKGWVDQALSRSVDIVLSIPGLIFSLMLLAIFGSNVWSL
ILIIAVLDSTNFYRLARTSGLSVASMEFIEAARLRGERPTWIVFREILPNILPPLIAEAGLRFCFVFLTISALSFLGVGI
QPPTADWGSMVRENATLITYGDITPLLPAAAIGLLTVAVNFVVDWFLTNLSGIKDGH

Sequences:

>Translated_297_residues
MSTIQNTALQRKRFKPGRSRRGRAWKALSRAPLSAWFGIVVVLTYAGTALFAPQLAPYGEAQVFPEPFAPWSADFVLGTD
QLGRDVLTRLIYGARNTLGIAVITTTLSFFFGVSLGVTAALLKGWVDQALSRSVDIVLSIPGLIFSLMLLAIFGSNVWSL
ILIIAVLDSTNFYRLARTSGLSVASMEFIEAARLRGERPTWIVFREILPNILPPLIAEAGLRFCFVFLTISALSFLGVGI
QPPTADWGSMVRENATLITYGDITPLLPAAAIGLLTVAVNFVVDWFLTNLSGIKDGH
>Mature_296_residues
STIQNTALQRKRFKPGRSRRGRAWKALSRAPLSAWFGIVVVLTYAGTALFAPQLAPYGEAQVFPEPFAPWSADFVLGTDQ
LGRDVLTRLIYGARNTLGIAVITTTLSFFFGVSLGVTAALLKGWVDQALSRSVDIVLSIPGLIFSLMLLAIFGSNVWSLI
LIIAVLDSTNFYRLARTSGLSVASMEFIEAARLRGERPTWIVFREILPNILPPLIAEAGLRFCFVFLTISALSFLGVGIQ
PPTADWGSMVRENATLITYGDITPLLPAAAIGLLTVAVNFVVDWFLTNLSGIKDGH

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=29.4545454545455, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789964, Length=243, Percent_Identity=37.4485596707819, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787760, Length=274, Percent_Identity=30.2919708029197, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789889, Length=229, Percent_Identity=30.1310043668122, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787549, Length=286, Percent_Identity=30.4195804195804, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787498, Length=207, Percent_Identity=32.3671497584541, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788505, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32306; Mature: 32175

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIQNTALQRKRFKPGRSRRGRAWKALSRAPLSAWFGIVVVLTYAGTALFAPQLAPYGE
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AQVFPEPFAPWSADFVLGTDQLGRDVLTRLIYGARNTLGIAVITTTLSFFFGVSLGVTAA
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLKGWVDQALSRSVDIVLSIPGLIFSLMLLAIFGSNVWSLILIIAVLDSTNFYRLARTSG
HHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHCC
LSVASMEFIEAARLRGERPTWIVFREILPNILPPLIAEAGLRFCFVFLTISALSFLGVGI
CCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPPTADWGSMVRENATLITYGDITPLLPAAAIGLLTVAVNFVVDWFLTNLSGIKDGH
CCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STIQNTALQRKRFKPGRSRRGRAWKALSRAPLSAWFGIVVVLTYAGTALFAPQLAPYGE
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AQVFPEPFAPWSADFVLGTDQLGRDVLTRLIYGARNTLGIAVITTTLSFFFGVSLGVTAA
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLKGWVDQALSRSVDIVLSIPGLIFSLMLLAIFGSNVWSLILIIAVLDSTNFYRLARTSG
HHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHCC
LSVASMEFIEAARLRGERPTWIVFREILPNILPPLIAEAGLRFCFVFLTISALSFLGVGI
CCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPPTADWGSMVRENATLITYGDITPLLPAAAIGLLTVAVNFVVDWFLTNLSGIKDGH
CCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]