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The map label for this gene is hbpA [H]

Identifier: 209551970

GI number: 209551970

Start: 33381

End: 34937

Strand: Reverse

Name: hbpA [H]

Synonym: Rleg2_6105

Alternate gene names: 209551970

Gene position: 34937-33381 (Counterclockwise)

Preceding gene: 209551971

Following gene: 209551963

Centisome position: 11.32

GC content: 54.34

Gene sequence:

>1557_bases
ATGCTGGATTTGAACCGTAGAACGCTACTAAAAGGTGCAGCCGCCGCTGCGGCATACACGTTTACTTCTTTGGGCCCGGC
AAGGGCTACTTCAAGCTCGCCGCGCCGAGGAGGGCATCTTCGCATCGGTCTTTGGGGAGGATCCTCACAGGACACGCTAG
ATCCGGCTAGCATCACTACCGATGCGGGGTTCCTCACGGCGGCCACCGCACGGAACAAGTTGTTAGAGGTCGAACCGAAT
GGTGAGCTTACCCCAGCCCTCGCATTAAAGTGGGAGCCATCGGATGACCTCATGCGTTGGACCTTTGAAATTCGGCCTGG
GGTGACTTTTCACAGCGGCAAGTCGCTTGAAATGTCGGACATCGTCGCTTCGCTCAACCTGCATCGCGGAAAGGACTCAA
CCTCTCCCGCAAAATCCTTCCTTGACGCGGTCACTGATATCAAGGCCGAGGGCAGTAACAGAGTTGTCGTCTCGCTCAAT
GCTCCGAACGTCGACTTTCCAAGTGCCCTCGCGGACCTCTCGCTGTCCATCGTGCCCGCGAAGGATGGGGTAGCAGATCG
GAACACGATGGACGGTACTGGCCCGTACGCAATCGAGAGCTTTGAGCCTGGCCAGCGCATAAGGTTCAAGCGAAACCCTA
ATTACTGGAATCTGGATAAGGCTGCATTCTTCGACTCGGCCGAGGTCCTGATCCTCGCTGATGCCGCTACAAGAATGAAC
GCTTTGCGCTCGGGTCAGGTTGATTTGATAAACCAAGCCGACCTTAAGACACTTAGCATGCTTCAGCGGGTCCCGGGAAT
AACCGTTGAAGACGTGCCCAGCGGCCGGTTTTATATTTTTGGCATGATGTCGGACGTTGCTCCTTTCAATGACAAGGATG
TACGACAGGCTCTGAAATTTGCGATCAACCGAAAGGAGATGACCCAGAAGATTCTCCTTGGGCATGGGAGCATTGGGAAT
GACCAGCCTATCAAGCCCAGCCACAAGTACTTCAATACGAACCTTCCGCAACGTGAGTATGATCCCGAAAAAGCGAAATT
TCATCTTAAACAAGCTGGCGTGACGTCACTTCAAGTACCTTTGAGTGTGGCCGAGGCCGCATTCGCCGGGGCTGTAAATG
CGGGGCAGCTTTTTGTCGCCTCGGCTGCTGAAGCAGGCATCAACATCGTCGCAACGCGGGAGCCCGATGATGGTTACTTC
GACAACGTTTGGCTGAAAAAGCCGTTTACCGCCGACTATTGGACTGAACTGCCGTCCGCTGATGCGCAGTTCACGCAAGG
CTATGCTAAGGGAGCAGCTTGGAACGAGACGCACTTCGACAACCCTCGCTTCAACGAACTCTTGCTGAAGGCCCGAGCTA
CGCTGGATGAGCAGCAGCGCGCGGGGATGTACCACGAAATGCAACAACTCATCCATGATGAAAGCGGTGCGATCATTCCA
ATGTTCGCGAACAATACCTGGGCTTCCAAATCAACGTTGAAGCATCAGGACGGATTGTCCAGCCATCGCGATCTCGATGA
TTTCCGTTGCATTGAGAGGTGGTGGTTCGAATCCTAA

Upstream 100 bases:

>100_bases
GTCTTTCAGTTCCGCCCCGAAATCCGGTTGACATCTCCGCAGGCACGCCTAAGATACTATATCGTATAAAAAACTACAAA
CCGGTATCGGAGGGGTTTTC

Downstream 100 bases:

>100_bases
GCGAGCGGCAGAGTGGCCTCTCTGTGTCGATGAGCAGTCGCAACTGCGAAAATCGATACTCTTATCAAGCGAAGATGGTT
ACGGCACGGGCGGGTATGTG

Product: extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLDLNRRTLLKGAAAAAAYTFTSLGPARATSSSPRRGGHLRIGLWGGSSQDTLDPASITTDAGFLTAATARNKLLEVEPN
GELTPALALKWEPSDDLMRWTFEIRPGVTFHSGKSLEMSDIVASLNLHRGKDSTSPAKSFLDAVTDIKAEGSNRVVVSLN
APNVDFPSALADLSLSIVPAKDGVADRNTMDGTGPYAIESFEPGQRIRFKRNPNYWNLDKAAFFDSAEVLILADAATRMN
ALRSGQVDLINQADLKTLSMLQRVPGITVEDVPSGRFYIFGMMSDVAPFNDKDVRQALKFAINRKEMTQKILLGHGSIGN
DQPIKPSHKYFNTNLPQREYDPEKAKFHLKQAGVTSLQVPLSVAEAAFAGAVNAGQLFVASAAEAGINIVATREPDDGYF
DNVWLKKPFTADYWTELPSADAQFTQGYAKGAAWNETHFDNPRFNELLLKARATLDEQQRAGMYHEMQQLIHDESGAIIP
MFANNTWASKSTLKHQDGLSSHRDLDDFRCIERWWFES

Sequences:

>Translated_518_residues
MLDLNRRTLLKGAAAAAAYTFTSLGPARATSSSPRRGGHLRIGLWGGSSQDTLDPASITTDAGFLTAATARNKLLEVEPN
GELTPALALKWEPSDDLMRWTFEIRPGVTFHSGKSLEMSDIVASLNLHRGKDSTSPAKSFLDAVTDIKAEGSNRVVVSLN
APNVDFPSALADLSLSIVPAKDGVADRNTMDGTGPYAIESFEPGQRIRFKRNPNYWNLDKAAFFDSAEVLILADAATRMN
ALRSGQVDLINQADLKTLSMLQRVPGITVEDVPSGRFYIFGMMSDVAPFNDKDVRQALKFAINRKEMTQKILLGHGSIGN
DQPIKPSHKYFNTNLPQREYDPEKAKFHLKQAGVTSLQVPLSVAEAAFAGAVNAGQLFVASAAEAGINIVATREPDDGYF
DNVWLKKPFTADYWTELPSADAQFTQGYAKGAAWNETHFDNPRFNELLLKARATLDEQQRAGMYHEMQQLIHDESGAIIP
MFANNTWASKSTLKHQDGLSSHRDLDDFRCIERWWFES
>Mature_518_residues
MLDLNRRTLLKGAAAAAAYTFTSLGPARATSSSPRRGGHLRIGLWGGSSQDTLDPASITTDAGFLTAATARNKLLEVEPN
GELTPALALKWEPSDDLMRWTFEIRPGVTFHSGKSLEMSDIVASLNLHRGKDSTSPAKSFLDAVTDIKAEGSNRVVVSLN
APNVDFPSALADLSLSIVPAKDGVADRNTMDGTGPYAIESFEPGQRIRFKRNPNYWNLDKAAFFDSAEVLILADAATRMN
ALRSGQVDLINQADLKTLSMLQRVPGITVEDVPSGRFYIFGMMSDVAPFNDKDVRQALKFAINRKEMTQKILLGHGSIGN
DQPIKPSHKYFNTNLPQREYDPEKAKFHLKQAGVTSLQVPLSVAEAAFAGAVNAGQLFVASAAEAGINIVATREPDDGYF
DNVWLKKPFTADYWTELPSADAQFTQGYAKGAAWNETHFDNPRFNELLLKARATLDEQQRAGMYHEMQQLIHDESGAIIP
MFANNTWASKSTLKHQDGLSSHRDLDDFRCIERWWFES

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=456, Percent_Identity=24.3421052631579, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789887, Length=518, Percent_Identity=23.9382239382239, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787495, Length=483, Percent_Identity=23.6024844720497, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787762, Length=465, Percent_Identity=24.7311827956989, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787551, Length=456, Percent_Identity=24.5614035087719, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787052, Length=453, Percent_Identity=23.6203090507726, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789397, Length=286, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57043; Mature: 57043

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLNRRTLLKGAAAAAAYTFTSLGPARATSSSPRRGGHLRIGLWGGSSQDTLDPASITT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEC
DAGFLTAATARNKLLEVEPNGELTPALALKWEPSDDLMRWTFEIRPGVTFHSGKSLEMSD
CCCCEEEECCCCCEEEECCCCCCCCEEEEEECCCCCEEEEEEEECCCEEECCCCCCCHHH
IVASLNLHRGKDSTSPAKSFLDAVTDIKAEGSNRVVVSLNAPNVDFPSALADLSLSIVPA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCEEEEEEC
KDGVADRNTMDGTGPYAIESFEPGQRIRFKRNPNYWNLDKAAFFDSAEVLILADAATRMN
CCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHCCCCCEEEEECCHHHHH
ALRSGQVDLINQADLKTLSMLQRVPGITVEDVPSGRFYIFGMMSDVAPFNDKDVRQALKF
HHHCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
AINRKEMTQKILLGHGSIGNDQPIKPSHKYFNTNLPQREYDPEKAKFHLKQAGVTSLQVP
HHCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHEEHHHCCCCEEECH
LSVAEAAFAGAVNAGQLFVASAAEAGINIVATREPDDGYFDNVWLKKPFTADYWTELPSA
HHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHHCCCC
DAQFTQGYAKGAAWNETHFDNPRFNELLLKARATLDEQQRAGMYHEMQQLIHDESGAIIP
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCHHHHHHHHHHCCCCCEEE
MFANNTWASKSTLKHQDGLSSHRDLDDFRCIERWWFES
EECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLDLNRRTLLKGAAAAAAYTFTSLGPARATSSSPRRGGHLRIGLWGGSSQDTLDPASITT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEC
DAGFLTAATARNKLLEVEPNGELTPALALKWEPSDDLMRWTFEIRPGVTFHSGKSLEMSD
CCCCEEEECCCCCEEEECCCCCCCCEEEEEECCCCCEEEEEEEECCCEEECCCCCCCHHH
IVASLNLHRGKDSTSPAKSFLDAVTDIKAEGSNRVVVSLNAPNVDFPSALADLSLSIVPA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCEEEEEEC
KDGVADRNTMDGTGPYAIESFEPGQRIRFKRNPNYWNLDKAAFFDSAEVLILADAATRMN
CCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHCCCCCEEEEECCHHHHH
ALRSGQVDLINQADLKTLSMLQRVPGITVEDVPSGRFYIFGMMSDVAPFNDKDVRQALKF
HHHCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
AINRKEMTQKILLGHGSIGNDQPIKPSHKYFNTNLPQREYDPEKAKFHLKQAGVTSLQVP
HHCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHEEHHHCCCCEEECH
LSVAEAAFAGAVNAGQLFVASAAEAGINIVATREPDDGYFDNVWLKKPFTADYWTELPSA
HHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHHCCCC
DAQFTQGYAKGAAWNETHFDNPRFNELLLKARATLDEQQRAGMYHEMQQLIHDESGAIIP
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCHHHHHHHHHHCCCCCEEE
MFANNTWASKSTLKHQDGLSSHRDLDDFRCIERWWFES
EECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]