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The map label for this gene is hyi [H]

Identifier: 209550689

GI number: 209550689

Start: 3182721

End: 3183491

Strand: Direct

Name: hyi [H]

Synonym: Rleg2_3113

Alternate gene names: 209550689

Gene position: 3182721-3183491 (Clockwise)

Preceding gene: 209550686

Following gene: 209550691

Centisome position: 70.14

GC content: 65.11

Gene sequence:

>771_bases
ATGCGACATTATTCAGCCTGCATAGAGTGGCTGTTTGCCGAAGAAGGCGACAGCTTTCCCGATCGCATCCGCCGCGCCCA
TGCCGACGGCCTGACGGCGATCGAATTCTGGCGCTGGACCGACAAGGATCTGGACGCGATCGAGGCGGCGCTTGATGAAA
CCGGCCTTGCCGTCACCAGCATCGTCGCCGAGCCGATGATCGCGCTGACCGACGCCGGCAACCGGCAGGCATGGCTGAAA
GGCTTGGCCCAATCCGTCGCCGCCGCAAAGCGTCTCGGCGCGCCCGTGCTGATTGCCCAGGCCGGCAACGATCTTCCGGG
CGTGACCCGCGAGCAGCAGCGCCGGGCGCTCACCGAAACGCTGAAGGCGGGCGCCGATATTCTTCGCGGCAGCGGTGTGC
GCCTCGGCGTCGAGCCGCTCAACATCCGCATCGACCATATCGGCTATTTTCTCGATTCAACTAGCGAAGGTCTCGACATC
ATCGATGACATCGCCCGCCCCGAGATCGGCATCGTCTACGACATCTACCATTCCGCCGTGATGGGCGAGCGCACGGAAGA
GGTGCTGGACGGCCGTCTCGACCGTGTTTTCCACGTCCATGTCGCCGATCATCCCGGCCGCAACGAACCGGGCTCAGGCG
GCATCGACCTGGCCCACCGCCTCGGCTGGATCTTCGACAACGGCTATGACGGCGCCGTCGGGCTGGAATACCGGCCGACC
AGACCCGGCGCAGACGCAGTCAGGGCCGCGATCGCCTCGCTTGACGGTTAG

Upstream 100 bases:

>100_bases
CGAATGTTCCGCCAATGAAACCGCGCGTCAAGCACTGAGATGCCTCTTGCGGCGGGCACCGATCTGTCGCAGCCTGCATC
CCCACATGCGAGGAGTTTTC

Downstream 100 bases:

>100_bases
GTCGGGTTTGCGCCTTCGGCAAAGGCTTCAAGCTCGGGGTCGAAATCGACCTCGACGACATTGTTGAAGACGGCAGTGGC
CAGCATGATACCGGCAAAGG

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRHYSACIEWLFAEEGDSFPDRIRRAHADGLTAIEFWRWTDKDLDAIEAALDETGLAVTSIVAEPMIALTDAGNRQAWLK
GLAQSVAAAKRLGAPVLIAQAGNDLPGVTREQQRRALTETLKAGADILRGSGVRLGVEPLNIRIDHIGYFLDSTSEGLDI
IDDIARPEIGIVYDIYHSAVMGERTEEVLDGRLDRVFHVHVADHPGRNEPGSGGIDLAHRLGWIFDNGYDGAVGLEYRPT
RPGADAVRAAIASLDG

Sequences:

>Translated_256_residues
MRHYSACIEWLFAEEGDSFPDRIRRAHADGLTAIEFWRWTDKDLDAIEAALDETGLAVTSIVAEPMIALTDAGNRQAWLK
GLAQSVAAAKRLGAPVLIAQAGNDLPGVTREQQRRALTETLKAGADILRGSGVRLGVEPLNIRIDHIGYFLDSTSEGLDI
IDDIARPEIGIVYDIYHSAVMGERTEEVLDGRLDRVFHVHVADHPGRNEPGSGGIDLAHRLGWIFDNGYDGAVGLEYRPT
RPGADAVRAAIASLDG
>Mature_256_residues
MRHYSACIEWLFAEEGDSFPDRIRRAHADGLTAIEFWRWTDKDLDAIEAALDETGLAVTSIVAEPMIALTDAGNRQAWLK
GLAQSVAAAKRLGAPVLIAQAGNDLPGVTREQQRRALTETLKAGADILRGSGVRLGVEPLNIRIDHIGYFLDSTSEGLDI
IDDIARPEIGIVYDIYHSAVMGERTEEVLDGRLDRVFHVHVADHPGRNEPGSGGIDLAHRLGWIFDNGYDGAVGLEYRPT
RPGADAVRAAIASLDG

Specific function: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) [H]

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=249, Percent_Identity=31.7269076305221, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI300068964, Length=244, Percent_Identity=31.1475409836066, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1786718, Length=247, Percent_Identity=29.5546558704453, Blast_Score=103, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17530883, Length=246, Percent_Identity=27.2357723577236, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017643
- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =5.3.1.22 [H]

Molecular weight: Translated: 27829; Mature: 27829

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHYSACIEWLFAEEGDSFPDRIRRAHADGLTAIEFWRWTDKDLDAIEAALDETGLAVTS
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHH
IVAEPMIALTDAGNRQAWLKGLAQSVAAAKRLGAPVLIAQAGNDLPGVTREQQRRALTET
HHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
LKAGADILRGSGVRLGVEPLNIRIDHIGYFLDSTSEGLDIIDDIARPEIGIVYDIYHSAV
HHHHHHHHCCCCCEECCCEEEEEEEHHHHHHCCCCCCHHHHHHHCCCCCCEEHHHHHHHH
MGERTEEVLDGRLDRVFHVHVADHPGRNEPGSGGIDLAHRLGWIFDNGYDGAVGLEYRPT
HCCHHHHHHCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCEECCC
RPGADAVRAAIASLDG
CCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRHYSACIEWLFAEEGDSFPDRIRRAHADGLTAIEFWRWTDKDLDAIEAALDETGLAVTS
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHH
IVAEPMIALTDAGNRQAWLKGLAQSVAAAKRLGAPVLIAQAGNDLPGVTREQQRRALTET
HHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
LKAGADILRGSGVRLGVEPLNIRIDHIGYFLDSTSEGLDIIDDIARPEIGIVYDIYHSAV
HHHHHHHHCCCCCEECCCEEEEEEEHHHHHHCCCCCCHHHHHHHCCCCCCEEHHHHHHHH
MGERTEEVLDGRLDRVFHVHVADHPGRNEPGSGGIDLAHRLGWIFDNGYDGAVGLEYRPT
HCCHHHHHHCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCEECCC
RPGADAVRAAIASLDG
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8440684; 10561547; 9278503 [H]