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The map label for this gene is ampC [C]

Identifier: 209550524

GI number: 209550524

Start: 3004012

End: 3005166

Strand: Direct

Name: ampC [C]

Synonym: Rleg2_2947

Alternate gene names: 209550524

Gene position: 3004012-3005166 (Clockwise)

Preceding gene: 209550522

Following gene: 209550525

Centisome position: 66.2

GC content: 58.44

Gene sequence:

>1155_bases
ATGAAAAGCATTCGGATAAGAATATTATCGGCGGTTTTGCTCTCGGCCGGCGCTGCCACCAGCGCTTTTGCCGCCGACGA
GACCAATTTGAAGGCGATCACGGATGCGGCGATCAAGCCGATCATCGAGAAATACGCCATTCCCGGCATTGCCGTCGCCA
TCACCGCTAACGGCCAGGACCACATCTTCAACTATGGTGTCGAATCCAAGGACACCGGCAGGCCGGTGGCGCCGACCACG
CTCTTCGAACTCGGATCGATCAGCAAGACCTTCACGGTGACGCTGGCATCCTACGCGGAAGCAAGCGGACCGCTCTCGCT
GTCGGACAAGGCCGGCAAATTTCTGCCTGGAATGAAGGGTAAGCCGTTCGGCGATATCGCCCTGATGAACCTGGGCACCC
ACACGGCGGGCGGATTTCCGCTGCAGCTTCCCGATGAGATCAAAACCGAAAAACAGCTGCTCGGCTATTTCGAGACCTGG
CAGCCCTCCTATACCGCTGGGGCGCAGAGAAGTTATGCCAATCCCAGCATCGGCATGCTCGGCTATATCGTGGCAAAAGC
CATGCATGCGGATTTTGCGGCTTTGATGCAGGGCAAGCTGTTTGCCGGGCTCGGCTTGAAAAGCACCTATATCAATGTGC
CGAAAGCGCGGCTGGCGGATTATGCGCAAGGTTATAAGCGCAGCGGCGAGCCCGCCCGGATGACACCTGCCGTTCTCTCA
TCCGAAGCCTATGGCGTAAAATCCACCGCAGGCGACATGATCCGCTTCGTCGCCGCCAATATGGGCCTGGTCAAGCTCGA
CGAAAAACTGCAGCAGGCGATCACCAGCACCCATATCGGATATTTCAAAGCAGGGGCGATGACCCAGGATCTCATCTGGG
AGCAATATGCCTATCCCGCCGCGTTGAACGACTTGCTGGCGGGCAATTCCCCCGCAATGCTGAAGACCATGCCGGTCTCG
GAACTGCGGCCGCCGATGAAGCCGCGCGACGATGTGTGGATCAACAAGACCGGCTCGACCAACGGCTTCGGCGCCTATGT
CGCCTTCATCCCCAAACAACGGCTCGGCATCGTCATCCTGGCCAACAAGAACTATCCCAACGAGGATCGCGTCGCCGCAG
CCTATCAGATATTGACGGCGCTTGCGGCCGACTGA

Upstream 100 bases:

>100_bases
AGATATCATCATTTGTGATTGCAAAATAGCGCCGTTAAACGTCGTACCCATGCGCTTTTGCGCTTGTTTTGGCTGCTCTG
TCGATTGGAGGATGACGGTT

Downstream 100 bases:

>100_bases
TCGGAAAACAGGCTCCGGCCTCCGCGGCAAGGCGCACGGCATCGCTTCTGGATCACCCCTCCGGAAATCGAGTCAGACTT
TAGCCCGATGCCGAGCCAGC

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKSIRIRILSAVLLSAGAATSAFAADETNLKAITDAAIKPIIEKYAIPGIAVAITANGQDHIFNYGVESKDTGRPVAPTT
LFELGSISKTFTVTLASYAEASGPLSLSDKAGKFLPGMKGKPFGDIALMNLGTHTAGGFPLQLPDEIKTEKQLLGYFETW
QPSYTAGAQRSYANPSIGMLGYIVAKAMHADFAALMQGKLFAGLGLKSTYINVPKARLADYAQGYKRSGEPARMTPAVLS
SEAYGVKSTAGDMIRFVAANMGLVKLDEKLQQAITSTHIGYFKAGAMTQDLIWEQYAYPAALNDLLAGNSPAMLKTMPVS
ELRPPMKPRDDVWINKTGSTNGFGAYVAFIPKQRLGIVILANKNYPNEDRVAAAYQILTALAAD

Sequences:

>Translated_384_residues
MKSIRIRILSAVLLSAGAATSAFAADETNLKAITDAAIKPIIEKYAIPGIAVAITANGQDHIFNYGVESKDTGRPVAPTT
LFELGSISKTFTVTLASYAEASGPLSLSDKAGKFLPGMKGKPFGDIALMNLGTHTAGGFPLQLPDEIKTEKQLLGYFETW
QPSYTAGAQRSYANPSIGMLGYIVAKAMHADFAALMQGKLFAGLGLKSTYINVPKARLADYAQGYKRSGEPARMTPAVLS
SEAYGVKSTAGDMIRFVAANMGLVKLDEKLQQAITSTHIGYFKAGAMTQDLIWEQYAYPAALNDLLAGNSPAMLKTMPVS
ELRPPMKPRDDVWINKTGSTNGFGAYVAFIPKQRLGIVILANKNYPNEDRVAAAYQILTALAAD
>Mature_384_residues
MKSIRIRILSAVLLSAGAATSAFAADETNLKAITDAAIKPIIEKYAIPGIAVAITANGQDHIFNYGVESKDTGRPVAPTT
LFELGSISKTFTVTLASYAEASGPLSLSDKAGKFLPGMKGKPFGDIALMNLGTHTAGGFPLQLPDEIKTEKQLLGYFETW
QPSYTAGAQRSYANPSIGMLGYIVAKAMHADFAALMQGKLFAGLGLKSTYINVPKARLADYAQGYKRSGEPARMTPAVLS
SEAYGVKSTAGDMIRFVAANMGLVKLDEKLQQAITSTHIGYFKAGAMTQDLIWEQYAYPAALNDLLAGNSPAMLKTMPVS
ELRPPMKPRDDVWINKTGSTNGFGAYVAFIPKQRLGIVILANKNYPNEDRVAAAYQILTALAAD

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=375, Percent_Identity=44, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1786574, Length=387, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 41032; Mature: 41032

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIRIRILSAVLLSAGAATSAFAADETNLKAITDAAIKPIIEKYAIPGIAVAITANGQD
CCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
HIFNYGVESKDTGRPVAPTTLFELGSISKTFTVTLASYAEASGPLSLSDKAGKFLPGMKG
CEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
KPFGDIALMNLGTHTAGGFPLQLPDEIKTEKQLLGYFETWQPSYTAGAQRSYANPSIGML
CCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
GYIVAKAMHADFAALMQGKLFAGLGLKSTYINVPKARLADYAQGYKRSGEPARMTPAVLS
HHHHHHHHHHHHHHHHHCCHHCCCCCCHHEECCCHHHHHHHHHHHHCCCCCCCCCHHHHC
SEAYGVKSTAGDMIRFVAANMGLVKLDEKLQQAITSTHIGYFKAGAMTQDLIWEQYAYPA
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCHH
ALNDLLAGNSPAMLKTMPVSELRPPMKPRDDVWINKTGSTNGFGAYVAFIPKQRLGIVIL
HHHHHHCCCCCCEEEECCHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEE
ANKNYPNEDRVAAAYQILTALAAD
ECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSIRIRILSAVLLSAGAATSAFAADETNLKAITDAAIKPIIEKYAIPGIAVAITANGQD
CCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
HIFNYGVESKDTGRPVAPTTLFELGSISKTFTVTLASYAEASGPLSLSDKAGKFLPGMKG
CEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
KPFGDIALMNLGTHTAGGFPLQLPDEIKTEKQLLGYFETWQPSYTAGAQRSYANPSIGML
CCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
GYIVAKAMHADFAALMQGKLFAGLGLKSTYINVPKARLADYAQGYKRSGEPARMTPAVLS
HHHHHHHHHHHHHHHHHCCHHCCCCCCHHEECCCHHHHHHHHHHHHCCCCCCCCCHHHHC
SEAYGVKSTAGDMIRFVAANMGLVKLDEKLQQAITSTHIGYFKAGAMTQDLIWEQYAYPA
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCHH
ALNDLLAGNSPAMLKTMPVSELRPPMKPRDDVWINKTGSTNGFGAYVAFIPKQRLGIVIL
HHHHHHCCCCCCEEEECCHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEE
ANKNYPNEDRVAAAYQILTALAAD
ECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8703429 [H]