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The map label for this gene is dctB [H]

Identifier: 209550298

GI number: 209550298

Start: 2764482

End: 2766353

Strand: Direct

Name: dctB [H]

Synonym: Rleg2_2718

Alternate gene names: 209550298

Gene position: 2764482-2766353 (Clockwise)

Preceding gene: 209550296

Following gene: 209550299

Centisome position: 60.92

GC content: 64.9

Gene sequence:

>1872_bases
ATGCACAAATCCGCCATGTCCCTGTCTCTGTCATCGCTGTGGCCTTCCCTGCCCCTGCGGCACCGCATCCGCCGGATGTG
GTGGGCTTATGCGGTGATCGCGCTTGTTGCCGCCGCCCTCGGCCTGTGGGCAAGCGGCGAGATCGGCCGGCGCCATGCCG
AGGCGGCTCTCGAAGAACAGGCCCGCACCGATGCCAGGCTGAATGCGGCATTGCTGCGCACGGTTCTCGAAAAATACCGG
GCGCTACCCTTCGTGCTGTCGCAGGATACGGCACTCGCCGCAGCGCTTGCGGGAAACGATGCCGGCACCTTCGAGCGGCT
CAGCCAGAAGCTGGAGATGCTGGCGGCGGGCACCAAGGCGGCGGTCATCTACGTCATCGACAAGGACGGCATGGCGGTTG
CGGCCAGCAACTGGCGCGAACCGACGAGCTTTGTCGGCAACGACTATCGTTTTCGGGAATATTTTCAGGGTGCGGTCGCT
GAAGGACAGGCCGAGCACTTCGCGCTCGGCACCGTCAGCAAGAAACCCGGCCTTTATATCTCCGAGCGGATATCAGGCAG
CACCGGGCTGCTCGGGGTCGTCGTTGTGAAGGTCGAGTTCGACGACGTCGAGGCGGATTGGAGCGCCACGGACGCCCCCT
CCTATGTGATCGACGACCGCGGTATCGTCCTCATCACCAGCATTCCCTCCTGGCGATTTATGACGATCGGGCGGATTGCC
GACGACAAGTTGACGGCGATCCGCGAAAGCCTGCAATTCGGCGACGCGCCGCTGCAGCCGCTGCCGCTCGATACCGGGCG
AAGTCTGGGCGAGAACCTCGACGTCGTCGAAATCGTCATGCCGGGCGGCGCCGGGAAAACCAGCTTTCTCGATGTCGGAA
TGCCGGTTCCCGCGACCGCCTGGCATTTGCAGCATCTCGTGGCGCTGGGTCCGTCCGTCGATGCCGGCATTCGCGAGGCC
CGCATGCTGGCGCTGCTGACGCTCTTGCCGCTGTTGGCCGGCGCCGCCTTCCTGCTGCGCCGCCGCCAGGCTGTCACTCT
CAGGATATTGAGCGAACAGCAGGCGCGGGAGGAACTGGAACGGCGTGTCGCCGAACGGACACAGGATCTCAGCCAGGCGC
GGGATCGGCTGCAGGCCGAAATCGTCGGCCACAGGAGCACCGAGCAGAAATTGCAGGCGGTGCAGCAGGATCTGGTGCAG
GCCAACCGGCTGGCAATCCTCGGCCAGGTGGCCGCCGGCGTCGCCCATGAGATCAACCAGCCGGTGGCCACCATCCGCGC
CTATGCCGATAATGCCCGCACCTTTCTCGACCGCGGCCAGACGGCGCCGGCCGGTGAAAATCTCGAAAGCATCGCGGCGC
TGACGGAACGCATCGGCTCGATCACCGAGGAGCTGAAGAGCTTTGCCCGCAAAGGCCGCGGCAGCGCTGAGCCGACAGGC
TTGAAGGATGTGATCGAAGGGGCGGTGATGCTGTTGCGCAGCCGCTTTGCCGGCCGCATGGACACGCTCGACATCGACCT
GCCGCCGCCCGACCTGCAGGTCATGGGCAACAGGATCCGCCTCGAACAGGTGCTGATCAACCTGCTTCAGAACGCGCTGG
AAGCGGTGGCGCCGAAGGCCGACGAGGCGCGTGTCGAGGTCAGGACGTCAAGCGAAGGGGACATGGTGACGTTGACGGTC
GCCGATAACGGCCCCGGCATTTCACCTGAAATCCGCAAGGGCTTGTTCACGCCGTTCAACACCTCGAAGGAAAGCGGCCT
CGGCCTCGGGCTGGTCATCTCCAAGGACATCGTCGGCGATTACGGCGGGCGGATGGAGGTTGACAGCGACGGCGGCGGGA
CCCGGTTCGTCGTTCATCTGAGGAAGGCTTGA

Upstream 100 bases:

>100_bases
CAAAATATTGATTTTATTCAATAAAAATTTTTAAGGCCGCTGACAGCCCATTAAGAAATGCGGAAATCCGCACAAATCTA
TTTGCAACCAGTGCAGAAAA

Downstream 100 bases:

>100_bases
GATCATGGCCACACCGATGCCCGTTGCGCTGATCGACGACGACAAGGATTTGCGCCGCGCCACCGCCCAGACGCTCGAAC
TCGCCGGATTCTCGGTTTTC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MHKSAMSLSLSSLWPSLPLRHRIRRMWWAYAVIALVAAALGLWASGEIGRRHAEAALEEQARTDARLNAALLRTVLEKYR
ALPFVLSQDTALAAALAGNDAGTFERLSQKLEMLAAGTKAAVIYVIDKDGMAVAASNWREPTSFVGNDYRFREYFQGAVA
EGQAEHFALGTVSKKPGLYISERISGSTGLLGVVVVKVEFDDVEADWSATDAPSYVIDDRGIVLITSIPSWRFMTIGRIA
DDKLTAIRESLQFGDAPLQPLPLDTGRSLGENLDVVEIVMPGGAGKTSFLDVGMPVPATAWHLQHLVALGPSVDAGIREA
RMLALLTLLPLLAGAAFLLRRRQAVTLRILSEQQAREELERRVAERTQDLSQARDRLQAEIVGHRSTEQKLQAVQQDLVQ
ANRLAILGQVAAGVAHEINQPVATIRAYADNARTFLDRGQTAPAGENLESIAALTERIGSITEELKSFARKGRGSAEPTG
LKDVIEGAVMLLRSRFAGRMDTLDIDLPPPDLQVMGNRIRLEQVLINLLQNALEAVAPKADEARVEVRTSSEGDMVTLTV
ADNGPGISPEIRKGLFTPFNTSKESGLGLGLVISKDIVGDYGGRMEVDSDGGGTRFVVHLRKA

Sequences:

>Translated_623_residues
MHKSAMSLSLSSLWPSLPLRHRIRRMWWAYAVIALVAAALGLWASGEIGRRHAEAALEEQARTDARLNAALLRTVLEKYR
ALPFVLSQDTALAAALAGNDAGTFERLSQKLEMLAAGTKAAVIYVIDKDGMAVAASNWREPTSFVGNDYRFREYFQGAVA
EGQAEHFALGTVSKKPGLYISERISGSTGLLGVVVVKVEFDDVEADWSATDAPSYVIDDRGIVLITSIPSWRFMTIGRIA
DDKLTAIRESLQFGDAPLQPLPLDTGRSLGENLDVVEIVMPGGAGKTSFLDVGMPVPATAWHLQHLVALGPSVDAGIREA
RMLALLTLLPLLAGAAFLLRRRQAVTLRILSEQQAREELERRVAERTQDLSQARDRLQAEIVGHRSTEQKLQAVQQDLVQ
ANRLAILGQVAAGVAHEINQPVATIRAYADNARTFLDRGQTAPAGENLESIAALTERIGSITEELKSFARKGRGSAEPTG
LKDVIEGAVMLLRSRFAGRMDTLDIDLPPPDLQVMGNRIRLEQVLINLLQNALEAVAPKADEARVEVRTSSEGDMVTLTV
ADNGPGISPEIRKGLFTPFNTSKESGLGLGLVISKDIVGDYGGRMEVDSDGGGTRFVVHLRKA
>Mature_623_residues
MHKSAMSLSLSSLWPSLPLRHRIRRMWWAYAVIALVAAALGLWASGEIGRRHAEAALEEQARTDARLNAALLRTVLEKYR
ALPFVLSQDTALAAALAGNDAGTFERLSQKLEMLAAGTKAAVIYVIDKDGMAVAASNWREPTSFVGNDYRFREYFQGAVA
EGQAEHFALGTVSKKPGLYISERISGSTGLLGVVVVKVEFDDVEADWSATDAPSYVIDDRGIVLITSIPSWRFMTIGRIA
DDKLTAIRESLQFGDAPLQPLPLDTGRSLGENLDVVEIVMPGGAGKTSFLDVGMPVPATAWHLQHLVALGPSVDAGIREA
RMLALLTLLPLLAGAAFLLRRRQAVTLRILSEQQAREELERRVAERTQDLSQARDRLQAEIVGHRSTEQKLQAVQQDLVQ
ANRLAILGQVAAGVAHEINQPVATIRAYADNARTFLDRGQTAPAGENLESIAALTERIGSITEELKSFARKGRGSAEPTG
LKDVIEGAVMLLRSRFAGRMDTLDIDLPPPDLQVMGNRIRLEQVLINLLQNALEAVAPKADEARVEVRTSSEGDMVTLTV
ADNGPGISPEIRKGLFTPFNTSKESGLGLGLVISKDIVGDYGGRMEVDSDGGGTRFVVHLRKA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=30.7407407407407, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=29.9145299145299, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=29.6, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=28.7671232876712, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=28.4584980237154, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=29.5652173913043, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789808, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=282, Percent_Identity=27.3049645390071, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=145, Percent_Identity=33.1034482758621, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1789149, Length=282, Percent_Identity=25.177304964539, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67510; Mature: 67510

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSAMSLSLSSLWPSLPLRHRIRRMWWAYAVIALVAAALGLWASGEIGRRHAEAALEEQ
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ARTDARLNAALLRTVLEKYRALPFVLSQDTALAAALAGNDAGTFERLSQKLEMLAAGTKA
HHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCE
AVIYVIDKDGMAVAASNWREPTSFVGNDYRFREYFQGAVAEGQAEHFALGTVSKKPGLYI
EEEEEECCCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEE
SERISGSTGLLGVVVVKVEFDDVEADWSATDAPSYVIDDRGIVLITSIPSWRFMTIGRIA
ECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCEEEEECCCC
DDKLTAIRESLQFGDAPLQPLPLDTGRSLGENLDVVEIVMPGGAGKTSFLDVGMPVPATA
CHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEECCCCCCHHH
WHLQHLVALGPSVDAGIREARMLALLTLLPLLAGAAFLLRRRQAVTLRILSEQQAREELE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRVAERTQDLSQARDRLQAEIVGHRSTEQKLQAVQQDLVQANRLAILGQVAAGVAHEINQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVATIRAYADNARTFLDRGQTAPAGENLESIAALTERIGSITEELKSFARKGRGSAEPTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LKDVIEGAVMLLRSRFAGRMDTLDIDLPPPDLQVMGNRIRLEQVLINLLQNALEAVAPKA
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
DEARVEVRTSSEGDMVTLTVADNGPGISPEIRKGLFTPFNTSKESGLGLGLVISKDIVGD
CCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCC
YGGRMEVDSDGGGTRFVVHLRKA
CCCEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MHKSAMSLSLSSLWPSLPLRHRIRRMWWAYAVIALVAAALGLWASGEIGRRHAEAALEEQ
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ARTDARLNAALLRTVLEKYRALPFVLSQDTALAAALAGNDAGTFERLSQKLEMLAAGTKA
HHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCE
AVIYVIDKDGMAVAASNWREPTSFVGNDYRFREYFQGAVAEGQAEHFALGTVSKKPGLYI
EEEEEECCCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEE
SERISGSTGLLGVVVVKVEFDDVEADWSATDAPSYVIDDRGIVLITSIPSWRFMTIGRIA
ECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCEEEEECCCC
DDKLTAIRESLQFGDAPLQPLPLDTGRSLGENLDVVEIVMPGGAGKTSFLDVGMPVPATA
CHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEECCCCCCHHH
WHLQHLVALGPSVDAGIREARMLALLTLLPLLAGAAFLLRRRQAVTLRILSEQQAREELE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRVAERTQDLSQARDRLQAEIVGHRSTEQKLQAVQQDLVQANRLAILGQVAAGVAHEINQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVATIRAYADNARTFLDRGQTAPAGENLESIAALTERIGSITEELKSFARKGRGSAEPTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LKDVIEGAVMLLRSRFAGRMDTLDIDLPPPDLQVMGNRIRLEQVLINLLQNALEAVAPKA
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
DEARVEVRTSSEGDMVTLTVADNGPGISPEIRKGLFTPFNTSKESGLGLGLVISKDIVGD
CCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCC
YGGRMEVDSDGGGTRFVVHLRKA
CCCEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]