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The map label for this gene is 209549385

Identifier: 209549385

GI number: 209549385

Start: 1840114

End: 1841424

Strand: Reverse

Name: 209549385

Synonym: Rleg2_1791

Alternate gene names: NA

Gene position: 1841424-1840114 (Counterclockwise)

Preceding gene: 209549387

Following gene: 209549384

Centisome position: 40.58

GC content: 61.94

Gene sequence:

>1311_bases
ATGGCACTGCTGACCTCTTTGAACCACAGGCTTCTATCGCGACGCGCGCTGCTGTCAGCGGGTGCCGCGGCCGGCTTATC
CGCCGTTCTGCTTCCGCTGGCGTCGGAAGCCGCCGACGTTATAGGCACCCCAGCCGGGGAAATCCGACCATTCAGGGCCG
ACATCCCCGAGGCAGCGCTTGAGGATCTCAGGCGGCGACTTGCCGAAACCCGATGGCCCGACGGCGAAACCGTCACGGAT
CGTTCGCAGGGTGTTGAGCCTGACAGGCTGAAGGAGCTGGTGGGCTACTGGCAATCGTCCTACGACTGGCGCAAGGCAGA
GAGCCGGCTGAATGCCTTTCCGCAATTTCTCACCAATATCGACGGTGTGGACATCCATTTCATCCATGTCCGTTCCCGCC
ATGAAAACGCCCTGCCGTTGATCATGACCCATGGCTGGCCGGGTTCGGTGTTCGAACTGCTCGATGTCATCGGGCCGCTC
ACGGACCCGACGGCGCATGGCGGTACGGCCGAGGATGCTTTCCACCTGGTGATCCCTTCGATTCCGGGATTCGGCTTCTC
CGGGAAGCCGTCGACGACGGGTTGGAACCCGCAGCGGATAGCGGCTGCCTGGGACGTGCTGATGAAACGGCTCGACTATA
TCAGCTATGTCGCGCAAGGCGGCGACTGGGGCGCCATCATCAGCGACGCCCTGGGTCGCGAGGCACCCGATGGGCTGCTC
GCCATCCATGTCAACAGGATCGAGCGGGCGACGACGTTCCCATCGGACGCAGCCCAGGCTCTTAGAAATGGAGGGACGGC
TCCCGACAATCTGTCTGCGGACGAGAAGCTCGTCTTCGACGAGGCGCGGAACTTCCTCAACAACGGCTTCGGCTATGCCG
CGATCATGAGCACACGTCCGGAGACAGTCGGTTACGGCATTGCGGATTCGCCAGTTGGCCTTGCCGCCTGGCTTTACGAC
AAGATCGCCGACTGGGTGTTCACCCGAGGCGATCCGGAACAGGCGCTTGGCAAGGAGGCGATCCTCGACAATATCACGCT
GTACTGGCTGACGAACACCGGCCCCTCGAGTGGCCGCATCTATTTCGAAAACGCCATGGCAGGCGCGAAGCTCTCGGAGG
TCAAAGTGCCGGTCGCCGTCACCATATTCCCCGGAGAGGTCTACAAACCGCCGAAGCACTGGTTGTCGAAGGCCTATCCG
AAGCTGGTGTACTATAACCGCGCGTCCAAGGGCGGCCACTTCGCGGCCTGGGAGGAGCCGGAACTCTTCAGTCAGGAGAT
CAGGGCAGGGTTCAAAACGGTGCGATCATGA

Upstream 100 bases:

>100_bases
GGAAGAGCTGATATGACTGACATCACATTGAACCCGTCACCAATGGCACCCCTTGCCGAACCTGTCCGTTGACTCTCGAT
GTCATGAAAGGACACACGTC

Downstream 100 bases:

>100_bases
GCAACCGTCGATAGTAATTGCCGAAGTTTCAGTGGCGGGGGCAGGGCGAGCTTTGCGTCCGCCAGACAGGTCGTCGATTG
ACGTCGATTACGCAACGCTT

Product: Epoxide hydrolase domain-containing protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MALLTSLNHRLLSRRALLSAGAAAGLSAVLLPLASEAADVIGTPAGEIRPFRADIPEAALEDLRRRLAETRWPDGETVTD
RSQGVEPDRLKELVGYWQSSYDWRKAESRLNAFPQFLTNIDGVDIHFIHVRSRHENALPLIMTHGWPGSVFELLDVIGPL
TDPTAHGGTAEDAFHLVIPSIPGFGFSGKPSTTGWNPQRIAAAWDVLMKRLDYISYVAQGGDWGAIISDALGREAPDGLL
AIHVNRIERATTFPSDAAQALRNGGTAPDNLSADEKLVFDEARNFLNNGFGYAAIMSTRPETVGYGIADSPVGLAAWLYD
KIADWVFTRGDPEQALGKEAILDNITLYWLTNTGPSSGRIYFENAMAGAKLSEVKVPVAVTIFPGEVYKPPKHWLSKAYP
KLVYYNRASKGGHFAAWEEPELFSQEIRAGFKTVRS

Sequences:

>Translated_436_residues
MALLTSLNHRLLSRRALLSAGAAAGLSAVLLPLASEAADVIGTPAGEIRPFRADIPEAALEDLRRRLAETRWPDGETVTD
RSQGVEPDRLKELVGYWQSSYDWRKAESRLNAFPQFLTNIDGVDIHFIHVRSRHENALPLIMTHGWPGSVFELLDVIGPL
TDPTAHGGTAEDAFHLVIPSIPGFGFSGKPSTTGWNPQRIAAAWDVLMKRLDYISYVAQGGDWGAIISDALGREAPDGLL
AIHVNRIERATTFPSDAAQALRNGGTAPDNLSADEKLVFDEARNFLNNGFGYAAIMSTRPETVGYGIADSPVGLAAWLYD
KIADWVFTRGDPEQALGKEAILDNITLYWLTNTGPSSGRIYFENAMAGAKLSEVKVPVAVTIFPGEVYKPPKHWLSKAYP
KLVYYNRASKGGHFAAWEEPELFSQEIRAGFKTVRS
>Mature_435_residues
ALLTSLNHRLLSRRALLSAGAAAGLSAVLLPLASEAADVIGTPAGEIRPFRADIPEAALEDLRRRLAETRWPDGETVTDR
SQGVEPDRLKELVGYWQSSYDWRKAESRLNAFPQFLTNIDGVDIHFIHVRSRHENALPLIMTHGWPGSVFELLDVIGPLT
DPTAHGGTAEDAFHLVIPSIPGFGFSGKPSTTGWNPQRIAAAWDVLMKRLDYISYVAQGGDWGAIISDALGREAPDGLLA
IHVNRIERATTFPSDAAQALRNGGTAPDNLSADEKLVFDEARNFLNNGFGYAAIMSTRPETVGYGIADSPVGLAAWLYDK
IADWVFTRGDPEQALGKEAILDNITLYWLTNTGPSSGRIYFENAMAGAKLSEVKVPVAVTIFPGEVYKPPKHWLSKAYPK
LVYYNRASKGGHFAAWEEPELFSQEIRAGFKTVRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=399, Percent_Identity=35.5889724310777, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI209862837, Length=399, Percent_Identity=35.5889724310777, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17564944, Length=416, Percent_Identity=34.1346153846154, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI193207462, Length=408, Percent_Identity=26.9607843137255, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI20130139, Length=407, Percent_Identity=32.9238329238329, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI19922580, Length=417, Percent_Identity=29.4964028776978, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24655327, Length=405, Percent_Identity=29.6296296296296, Blast_Score=175, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 47724; Mature: 47593

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLTSLNHRLLSRRALLSAGAAAGLSAVLLPLASEAADVIGTPAGEIRPFRADIPEAAL
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
EDLRRRLAETRWPDGETVTDRSQGVEPDRLKELVGYWQSSYDWRKAESRLNAFPQFLTNI
HHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
DGVDIHFIHVRSRHENALPLIMTHGWPGSVFELLDVIGPLTDPTAHGGTAEDAFHLVIPS
CCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
IPGFGFSGKPSTTGWNPQRIAAAWDVLMKRLDYISYVAQGGDWGAIISDALGREAPDGLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEE
AIHVNRIERATTFPSDAAQALRNGGTAPDNLSADEKLVFDEARNFLNNGFGYAAIMSTRP
EEEEHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
ETVGYGIADSPVGLAAWLYDKIADWVFTRGDPEQALGKEAILDNITLYWLTNTGPSSGRI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEE
YFENAMAGAKLSEVKVPVAVTIFPGEVYKPPKHWLSKAYPKLVYYNRASKGGHFAAWEEP
EEECCCCCCCHHHEECCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCH
ELFSQEIRAGFKTVRS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALLTSLNHRLLSRRALLSAGAAAGLSAVLLPLASEAADVIGTPAGEIRPFRADIPEAAL
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
EDLRRRLAETRWPDGETVTDRSQGVEPDRLKELVGYWQSSYDWRKAESRLNAFPQFLTNI
HHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
DGVDIHFIHVRSRHENALPLIMTHGWPGSVFELLDVIGPLTDPTAHGGTAEDAFHLVIPS
CCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
IPGFGFSGKPSTTGWNPQRIAAAWDVLMKRLDYISYVAQGGDWGAIISDALGREAPDGLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEE
AIHVNRIERATTFPSDAAQALRNGGTAPDNLSADEKLVFDEARNFLNNGFGYAAIMSTRP
EEEEHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
ETVGYGIADSPVGLAAWLYDKIADWVFTRGDPEQALGKEAILDNITLYWLTNTGPSSGRI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEE
YFENAMAGAKLSEVKVPVAVTIFPGEVYKPPKHWLSKAYPKLVYYNRASKGGHFAAWEEP
EEECCCCCCCHHHEECCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCH
ELFSQEIRAGFKTVRS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]