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The map label for this gene is dsdA [H]

Identifier: 209549220

GI number: 209549220

Start: 1647489

End: 1648811

Strand: Reverse

Name: dsdA [H]

Synonym: Rleg2_1621

Alternate gene names: 209549220

Gene position: 1648811-1647489 (Counterclockwise)

Preceding gene: 209549221

Following gene: 209549215

Centisome position: 36.33

GC content: 62.81

Gene sequence:

>1323_bases
ATGAACACGATACTGCCAGCCGACCCCGCTCGAGACGAGGTTCTCGCGGGCCGCCCCACCCTCTGGGTCAATCCGTCCTA
CCGGAAACGGGCGATCGACACGTCAGACCTGCCGGTTTCACGGGACGACGTACAGATTGCGCGCCTGAACTGGCAGCGCC
TGGCGCCGCTTCTTGCCGAGTGCTTTCCGGAACTGAAGGATTCCGACGGCGAGATCCGCTCCGAACTGGTGGAGCTCAAG
GAACTCCGCGAGGCGCTCGGCTATCGAACGAGAGAGTTCGGGAATGTTTTCATCAAGGCTGACAGCCACCTGCCGGTCGC
CGGCTCGATCAAGGCTCGCGGCGGCGTCTATGAGGTTTTCCTGTTTGCCGAGAATCTCGCCCGTCAGAACGGACTGCTCG
GCGATGGCGAAGATATCCGCAAGCTGGCAGCGGAGGAGGCCCGCTCGTTTTTCTCCGGCTATACCGTGGCGGTGGGCAGT
ACCGGCAATCTGGGCCTGAGCGTCGGCATTGCCGCGCGGGCCCTGGGCTTCAAAGCCACGGTTCACATGTCTTCCGACGC
GAAGGCCTGGAAAGTCGAGCGCCTCCGGCGGCTTGGAGTGGAAGTCATCCAGCACGAAGCGGATTATACGAGTGCGGTCG
AAAACGCCCGCGACATAGCCGACGCCGATCCGACGATCTATTTCGTCGACGACGAACAATCGCGGCACCTGTTCCTCGGT
TATAGCGCAGCGGCGTCGGAGCTGGCAGCGCAGCTCGACGAGCGTGGGATAACGATCGACGAGGAAAATCCCCTATTCCT
CTACCTTCCGTGCGGCATCGGTGGAGCGCCGGGCGGTGTTGCCTTCGGTGCCAAAGCGATCTTCGGCGACAATGTGCACG
CGTTCTTCGTCGAGCCGGTTCAGTCGCCCTGCACCCTCGTCCATATGATGTCGGGTTCGCAGGAGCTGGTGTCGGTCTAC
GACGTCGGCCTGACGAACAAGACCGAAGCCGACGGCATGGCCGTCGCCCGCATGTCGGCCTTCGTCGCCAAGGTGATGCG
CGAGATGCTCGCCGGCGTCTACACGGCCGCCGACGACGATCTGTTCAAGCTGCTTCGCATGGCATGGATCACCCAAAGAC
AAAAGCTGGAGCCCTCTGCCGCCGCCGCCTTGCTCGGCCCGCACTTCCTCGTGCACCATGGGGAAGGTCGGCGCTTCCAG
GCAGAACAGGGCATCGAGGAGAAGATGTCGCGGGCGACGCACATCCTCTGGACAACAGGCGGCTCATTCGTTCCGGAGGA
GCAGTTCCAGAACTTCCTTCGTCAGGCCGAAGCCGTCGGTTAG

Upstream 100 bases:

>100_bases
TCGACAATCCGAAAAGCGACCGCGCTCGCTCCTTCCTCGCACGCGTCCTAAAACACTGACCGCCCCAACGCAGACCGACC
CACGAACACTGGAAATCCGC

Downstream 100 bases:

>100_bases
TCCCATTCCGCCTGGTGCCGCAGGCGCGGGTCGGGAATGATCCGCGCCTGCGGATTCCGCTTCGTTTGCGCGACAGGCGT
TAGAATCGACGCGGGCCTTC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAECFPELKDSDGEIRSELVELK
ELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVFLFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGS
TGNLGLSVGIAARALGFKATVHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLG
YSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPVQSPCTLVHMMSGSQELVSVY
DVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDDLFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQ
AEQGIEEKMSRATHILWTTGGSFVPEEQFQNFLRQAEAVG

Sequences:

>Translated_440_residues
MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAECFPELKDSDGEIRSELVELK
ELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVFLFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGS
TGNLGLSVGIAARALGFKATVHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLG
YSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPVQSPCTLVHMMSGSQELVSVY
DVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDDLFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQ
AEQGIEEKMSRATHILWTTGGSFVPEEQFQNFLRQAEAVG
>Mature_440_residues
MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAECFPELKDSDGEIRSELVELK
ELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVFLFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGS
TGNLGLSVGIAARALGFKATVHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLG
YSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPVQSPCTLVHMMSGSQELVSVY
DVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDDLFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQ
AEQGIEEKMSRATHILWTTGGSFVPEEQFQNFLRQAEAVG

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=440, Percent_Identity=45.9090909090909, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17508781, Length=349, Percent_Identity=24.6418338108883, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 48178; Mature: 48178

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAE
CCCCCCCCCCCCCHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
CFPELKDSDGEIRSELVELKELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVF
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGSTGNLGLSVGIAARALGFKAT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHCCEEE
VHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
YSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPV
EHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCCHHHCCHHEECCCEEEEEECCC
QSPCTLVHMMSGSQELVSVYDVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDD
CCCHHEEHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQAEQGIEEKMSRATHILWTTG
HHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCEECHHCCHHHHHHHHEEEEEECC
GSFVPEEQFQNFLRQAEAVG
CCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTILPADPARDEVLAGRPTLWVNPSYRKRAIDTSDLPVSRDDVQIARLNWQRLAPLLAE
CCCCCCCCCCCCCHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
CFPELKDSDGEIRSELVELKELREALGYRTREFGNVFIKADSHLPVAGSIKARGGVYEVF
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LFAENLARQNGLLGDGEDIRKLAAEEARSFFSGYTVAVGSTGNLGLSVGIAARALGFKAT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHCCEEE
VHMSSDAKAWKVERLRRLGVEVIQHEADYTSAVENARDIADADPTIYFVDDEQSRHLFLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
YSAAASELAAQLDERGITIDEENPLFLYLPCGIGGAPGGVAFGAKAIFGDNVHAFFVEPV
EHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCCHHHCCHHEECCCEEEEEECCC
QSPCTLVHMMSGSQELVSVYDVGLTNKTEADGMAVARMSAFVAKVMREMLAGVYTAADDD
CCCHHEEHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFKLLRMAWITQRQKLEPSAAAALLGPHFLVHHGEGRRFQAEQGIEEKMSRATHILWTTG
HHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCEECHHCCHHHHHHHHEEEEEECC
GSFVPEEQFQNFLRQAEAVG
CCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA