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The map label for this gene is ygeV [H]

Identifier: 209400999

GI number: 209400999

Start: 3846736

End: 3848514

Strand: Reverse

Name: ygeV [H]

Synonym: ECH74115_4159

Alternate gene names: 209400999

Gene position: 3848514-3846736 (Counterclockwise)

Preceding gene: 209400720

Following gene: 209398939

Centisome position: 69.07

GC content: 45.81

Gene sequence:

>1779_bases
ATGGAGCTTGCTACTACGCAGTCAGTATTGATGCAAATTCAACCGACAATTCAGCGTTTTGCCAGAATGCTTGCCAGCGT
TTTGCAGCTTGAGGTTGAGATCGTTGATGAAAACTTGTATCGCGTCGCCGGAACGGGCGCGTATGGGAAGTTTCTTGGTC
GCCAGTTGAGCGGCAACTCACGCCTGCTCTGCCACGTCCTGGAAACGAAAACTGAAAAAGTTGTGACACAGTCTCGCTTC
GATCCCCTTTGCGAAGGTTGCGATAGTAAAGAAAATTGCCGCGAAAAAGCATTTCTGGGTACGCCTGTCATTTTACAGGA
TCGTTGTGTTGGGGTGATAAGTTTGATTGCCGTTACCCACGAGCAACAAGAGCATATCAGTGATAATTTACGCGAATTTT
CTGATTATGTTCGCCATATATCCACCATTTTTGTTTCGAAACTTCTGGAGGATCAGGGGCCAGGAGATAACATCAGTAAA
ATATTCGCGACCATGATCGATAATATGGATCAGGGCGTATTAGTTGTTGATGATGAAAGTCGGGTTCAGTTTGTTAATCA
GACTGCCTTAAAAACACTTGGTGTTGTGCAAAATAATATTATTGGGAAACCTATCCGTTTCAGACCATTAACATTTGAGA
GTAATTTTACCCATGGACATATGCAGCATATTGTTTCGTGGGACGATAAAAGTGAATTAATCATTGGTCAATTGCATAAC
ATTCAGGGCCGACAATTATTTTTAATGGCGTTTCACCAATCGCATACCAGTTTTTCTGTAGCAAATGCACCTGATGAACC
GCATATTGAACAATTGGTTGGCGAGTGCCGTGTTATGCGGCAATTAAAACGACTCATTAGCCGTATTGCACCCAGCCCAT
CCAGCGTTATGGTGGTTGGTGAAAGCGGCACGGGTAAAGAAGTTGTCGCCCGTGCAATCCATAAGTTGAGCGGAAGACGG
AATAAACCCTTTATTGCTATCAACTGTGCCGCGATTCCGGAGCAGCTTCTGGAGAGCGAACTGTTCGGTTATGTTAAAGG
CGCATTTACTGGCGCTTCTGCCAACGGTAAAACAGGGTTGATTCAGGCGGCGAATACGGGCACGCTGTTTCTCGATGAAA
TAGGTGATATGCCATTAATGTTGCAGGCTAAATTACTGCGCGCTATTGAGGCACGTGAAATTCTGCCGATTGGTGCCAGT
AGCCCAATACAAGTCGACATTCGCATCATTTCTGCAACTAACCAGAATTTGGCCCAGTTCATTGCCGAAGGTAAATTCCG
CGAAGATCTCTTCTACCGACTTAATGTTATCCCGATAACTCTGCCACCGCTGCGTGAACGTCAGGAAGATATTGAACTAC
TGGTGCATTACTTTTTACATCTGCATACCCGTCGTCTGGGATCGGTTTATCCTGGCATTGCTCCCGATGTCGTCGAAATA
TTGCGTAAGCATCGTTGGCCCGGAAACCTGCGCGAGTTAAGCAATTTGATGGAATATCTGGTTAACGTTGTTCCTTCAGG
TGAAGTTATCGACAGCACGCTATTGCCGCCAAATCTGCTGAATAATGGCACAACGGAGCAAAGTGATGTAACAGAGGTTA
CTGAGGCACACCTGTCACTCGATGATGCGGGCGGCACGGCGCTGGAGGAGATGGAAAAGCAAATGATCCGCGAGGCGCTT
TCACGTCATAACAGCAAGAAGCAAGTTGCTGATGAACTGGGCATCGGCATTGCTACGCTCTATCGCAAGATTAAGAAATA
TGAGTTGTTAAACACATAA

Upstream 100 bases:

>100_bases
TTTTATCAAAGCCAATTTCGCCTGAGTTAATATGATCATGATCTGTGAACCATCAACGTCTTCAATGATCGACTTTTAAG
TAAGTCTGGAAGGTAAAGCT

Downstream 100 bases:

>100_bases
CATCAGTGAATCCGGCCTGAATTCAGGCCGGATATCCTTTTACTTCGTTTTCTCGCAATCCAGAACTGTATTTACAATCA
TCTGATACCCCGTGCAGCGA

Product: sigma-54 dependent transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNSRLLCHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNT

Sequences:

>Translated_592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNSRLLCHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNT
>Mature_592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNSRLLCHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNT

Specific function: Unknown

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=592, Percent_Identity=99.3243243243243, Blast_Score=1206, Evalue=0.0,
Organism=Escherichia coli, GI1788550, Length=306, Percent_Identity=47.7124183006536, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=43.4650455927052, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI87082117, Length=328, Percent_Identity=42.3780487804878, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1790437, Length=318, Percent_Identity=42.4528301886792, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789087, Length=321, Percent_Identity=42.3676012461059, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1788905, Length=252, Percent_Identity=48.4126984126984, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1786524, Length=330, Percent_Identity=38.4848484848485, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=38.8198757763975, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=44.8275862068966, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1787583, Length=349, Percent_Identity=32.6647564469914, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789828, Length=264, Percent_Identity=35.6060606060606, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081858, Length=450, Percent_Identity=28.6666666666667, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66091; Mature: 66091

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHHHCCCCC
RLLCHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTH
EEEEEHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCH
RVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHHCC
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVG
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQF
EEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEECCCHHHHHH
IAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
HHCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCC
DDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHHHCCCCC
RLLCHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTH
EEEEEHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCH
RVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHHCC
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVG
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQF
EEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEECCCHHHHHH
IAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
HHCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCC
DDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]