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The map label for this gene is ycaI [H]

Identifier: 209400423

GI number: 209400423

Start: 1097318

End: 1099582

Strand: Direct

Name: ycaI [H]

Synonym: ECH74115_1074

Alternate gene names: 209400423

Gene position: 1097318-1099582 (Clockwise)

Preceding gene: 209396562

Following gene: 209398481

Centisome position: 19.69

GC content: 49.67

Gene sequence:

>2265_bases
ATGAAAATAACGACAGTCGGCGTATGCATAATTTGCGGAATTTTTCCGTTGCTGATTTTGCCCCAATTGCCTGGGACATT
AACCCTTGCGTTTCTGACTCTCTTCGCCTGCGTACTGGCATTTATCCCTGTTAAAACCGTCCGTTATATCGCGCTGACGT
TGCTGTTTTTCGTTTGGGGCATATTATCAGCAAAGCAAATTTTGTTGGCAGGAGAAACCTTAACTGGCGCGACGCAGGAT
GCAATTGTTGAGATCACTGCTACTGACGGCATGACCACTCATTACGGTCAAATTACTTATCTACAAGGTCAACGTATATT
CCCTGCGCCAGGCCTTGTGCTGTATGGCGAATATCTTCCGCAAGCGGTTTGTGCCGGACAACTGTGGTCAATGAAACTCA
AAGTTCGTGCCGTTCATGGTCAACTTAATGATGGCGGCTTTGATAGCCAGCGTTATGCCATTGCCCAGCATCAGCCGCTC
ACCGGCCGCTTTCTGCAGGCAAGTGTTATTGAACCGAATTGTAGCCTGCGTGCACAGTATCTGGCGTCACTACAAACAAC
GCTGCAACCCTATCCGTGGAATGCGGTTATTCTTGGTTTAGGTATGGGGGAACGGTTATCCGTCCCTAAAGAAATCAAAA
ATATCATGCGTGATACTGGAACGGCGCATTTAATGGCGATATCGGGATTGCACATCGCTTTTGCGGCGTTGCTGGCTGCC
GGACTCATTCGCAGTGGACAAATTTTTCTGCCTGGGCGCTGGATCCACTGGCAAATGCCATTAATTGGCGGAATCTGCTG
TGCTGCTTTTTATGCCTGGCTGACGGGAATGCAACCTCCTGCATTGCGTACCGTTGTGGCGCTTGCTACGTGGGGTATGC
TTAAGTTAAGTGGGCGACAGTGGAGTGGCTGGGATGTATGGATATGTTGTCTGGCGGCAATTTTGCTGATGGATCCTGTT
GTCATTCTCTCGCAAAGTTTATGGCTCTCTGCCGCTGCGGTCGCGGCATTGATATTTTGGTATCAGTGGTTTCCCTGTCC
TGAGTGGCAACTGCCGCCGGTATTGCGTGCAGTTGTTTCCCTCATCCATCTGCAACTGGGAATCACACTTCTGCTTATGC
CCGTGCAAATCGTCATTTTTCATGGCATTAGTCTGACCTCGTTTATTGCAAATCTATTAGCAATTCCCTTGGTGACATTT
ATCACGGTTCCGTTGATCCTCGCCGCGATGGTTGTGCATTTAAGCGGGCCGTTAATCCTGGATCAAGGGTTATGGTTTCT
TGCCGACCGGTCTTTGGCTTTACTTTTCTTGGGGTTAAAGAGTTTGCCAGAAGGGTGGATCAACATTGCTGAACGTTGGC
AATGGCTATCATTTTCCCCATGGTTCTTACTGGTGGTATGGCGATTAAACGCCTGGCGAACGTTGCCAGCAATGTGTGTG
GCTGTAGGCTTGCTGATGTGCTGGCCGCTGTGGCAAAAACCTCGACCTGACGAGTGGCAAGTGTACATGCTTGATGTCGG
GCAAGGGCTGGCAATGGTGATAGCCAGAAACGGCAAAGCGATTCTCTATGACACGGGACTGGCCTGGCCTGAAGGGGATA
GTGGGCAACAACTGATTATCCCCTGGCTCCACTGGCATAATCTTGAACCGGAAGGCGTTATCCTGAGTCATGAACATCTG
GATCACCGGGGAGGGCTGGACTCAATATTGCATACATGGCCGATGTTATGGATCAGAAGTCCGTTAAACTGGGAACATCA
TCAGCCCTGTGTGCGTGGCGAAGCGTGGCAATGGCAAGGATTGCGTTTCAGCGCGCACTGGCCTTTACAAGGTCGCAACG
ATAAAGGAAATAACCATTCCTGTGTGGTTAAGGTTGATGACGGGACGAATAGCATTCTTCTAACCGGTGATATTGAAGCC
CCAGCTGAACAAAAGATGCTAAGCCGTTACTGGCAGCAAGTGCAGGCAACATTGCTTCAGGTACCTCACCATGGCAGTAA
TACCTCATCATCATTGCCATTAATTCAGCGAGTGAATGGAAAAGTGGCACTCGCATCGGCATCGCGCTATAACGCATGGC
GACTGCCCTCTAACAAAGTTAAGCATCGCTATCAACAACAAGGTTATACGTGGCTTGATACTCCTCATCAGGGGCAAGTA
ACGGTCGATTTTTCAGCGCAAGGCTGGCGGATTAGCAGCCTCAGGGAGCAAATTTTACCTCGTTGGTATCATCAGTGGTT
TGGCGTGCCAGTGGATAACGGGTAG

Upstream 100 bases:

>100_bases
CTTTCGTTAAATTCTTCTGAATGTGCCTCGGGGAACGCAAAATTCCCACCAGACAACCGCTCAACAAAGTTGCACACTTT
CCATAAACAGGGAGGGGTGC

Downstream 100 bases:

>100_bases
AATATGCGGCTATTTCAACAAATGCTGGTTTTTTGAATGCATAACGACAAAGATCTCTCTACGTGGCAGACATTCCGCCG
ACTGTGGCCAACCATTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWGILSAKQILLAGETLTGATQD
AIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLPQAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
VILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTF
ITVPLILAAMVVHLSGPLILDQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG

Sequences:

>Translated_754_residues
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWGILSAKQILLAGETLTGATQD
AIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLPQAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
VILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTF
ITVPLILAAMVVHLSGPLILDQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG
>Mature_754_residues
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWGILSAKQILLAGETLTGATQD
AIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLPQAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
VILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTF
ITVPLILAAMVVHLSGPLILDQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG

Specific function: Unknown

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae Rec2 [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=754, Percent_Identity=97.0822281167109, Blast_Score=1452, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 84445; Mature: 84445

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWG
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSAKQILLAGETLTGATQDAIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLP
HHHHHHHEEECCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCEECCCCCEEEEHHHHH
QAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPLTGRFLQASVIEPNCSLRAQY
HHHHCCCHHEEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHH
LASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQ
HHHCCCCEEECCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCC
WSGWDVWICCLAAILLMDPVVILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVS
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTFITVPLILAAMVVHLSGPLIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
ECCCCEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLII
HHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEEE
PWLHWHNLEPEGVILSHEHLDHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQG
EEHHHCCCCCCCEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC
LRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQ
EEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCEEECCCCCCEE
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWG
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSAKQILLAGETLTGATQDAIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLP
HHHHHHHEEECCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCEECCCCCEEEEHHHHH
QAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPLTGRFLQASVIEPNCSLRAQY
HHHHCCCHHEEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHH
LASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQ
HHHCCCCEEECCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCC
WSGWDVWICCLAAILLMDPVVILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVS
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTFITVPLILAAMVVHLSGPLIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
ECCCCEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLII
HHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEEE
PWLHWHNLEPEGVILSHEHLDHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQG
EEHHHCCCCCCCEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC
LRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQ
EEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCEEECCCCCCEE
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 8094880 [H]